http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 서동석 (검색결과 136 건)
- 무료
- 기관 내 무료
- 유료
-
-
-
제 2형 당뇨모델 OLETF 랫드에서 동충하초의 항당뇨 효과
서동석,강종구,정미혜,권민,박철범 한국식품위생안전성학회 2013 한국식품위생안전성학회지 Vol.28 No.2
본 연구는 동충하초(Isaria tenuipes)를 유전적 당뇨 질환동물모델인 OLETF 랫드에서 4주간 경구 투여하여 항당뇨효과에 대한 연구결과로써, OLETF 랫드 동충하초(Isariatenuipes) 투여군은 당뇨대조군과 비교하여 투여 4주에는사료 섭취량과 체중이 증가하였다. 이는 동충하초(Isariatenuipes)를 섭취한 OLETF 랫드는 고지방식 사료만 섭취한 OLETF 랫드에 비해 당뇨 유발이 개선된 결과로 판단된다. 혈중 포도당 농도, 인슐린 농도 및 인슐린 저항성 지표인 HOMA-IR 수치가 용량 의존적으로 감소하였다. 또한GLUT4 유전자 발현을 측정한 결과 대조군에 비해 동충하초(Isaria tenuipes) 투여군의 mRNA 및 단백질이 용량의존적으로 증가하는 경향을 보였다. 따라서, 동충하초(Isaria tenuipes)의 섭취가 제2형 당뇨에서 인슐린의 감수성이나 저항성에 영향을 미치고, 혈당을 강화시키는 것으로 사료되므로 당뇨병환자의 혈당저하에 기여할 것이라기대한다. 이에 본 연구는 천연물질을 이용한 당뇨병의 예방 및 치료에 동충하초(Isaria tenuipes)를 사용할 수 있는이론적 토대를 제공할 것으로 생각된다. We evaluated the anti-diabetic effects of Isaria tenuipes in diabetes mellitus type 2. For the experiments,the diabetic animal model OLETF rats were divided to 4 groups: Isaria tenuipes was administered mixed with the high fat diet 45% at dose levels of 0.0%, 0.1%, 1.0%, and 5.0% for 4 weeks. All animals have free access to water and high fat diet 45%. The diabetic clinical markers, including clinical signs, body weight and food intake, organ weights, blood glucose level, insulin level and HOMA-IR index, oral glucose tolerance test, GLUT4 mRNA and protein were measured at a time. After administration for 4 weeks, the blood glucose levels, insulin levels and HOMAIR index of test groups were decreased compared with control group in dose-dependent manner. The body weight and diet consumptions were reduced in control group at 4 weeks. The treatments of Isaria tenuipes also showed high expression of GLUT4 mRNA and protein in the muscle of OLETF rats. The results suggest that Isaria tenuipes has anti-hyperglycemic effect attenuating blood glucose in the animal model of type 2 diabetes and might be useful as a functional diet for human diabetic diseases.
-
徐東錫 亞洲大學校 1983 論文集 Vol.6 No.-
This paper examines the changing pattern of revealed comparative advantage among the Advanced Industrialized Countries in the Pacific Basin (AICS), EEC, EFTA, the Asian Newly Industrializing Countries (NICS), and the ASEAN in the OECD market for the year 1971-1981. This analysis demonstrates that the traditional commodity group of Korea gradually lose their revealed comparative advantage in OECD market, while the non-traditional commodity group such as iron and steel and electronic machinery gain their competitiveness in OECD market. There exists a complex structure consisting of both competitive and complementary elements in the structure of comparative advantage of manufactured goods among the nation's group. This analysis also shows that the dynamic catch-up process among the AICS, NICS, and ASEAN in the manufactured goods is under way.
-
Ca/P 비에 따른 수산화아파타이트 생체재료의 표면용해 특성
서동석,김환,이종국,Seo, Dong-Seok,Kim, Hwan,Lee, Jong-Kook 한국세라믹학회 2004 한국세라믹학회지 Vol.41 No.1
Ca/P 비가 각각 1.62, 1.67, 1.72인 수산화아파타이트(Hydroxyapatite, HA) 세라믹스를 제조하고, HA 표면에서 수용액에 의하여 일어나는 용해현상을 고찰하였다. 수용액에서 3일간 침적시킨 경우 입계에서부터 용해가 시작되었으며, 침적시간이 10일로 증가하면서 이러한 입계용해에 의한 HA 세라믹스의 미세구조적 분해 현상은 비화학양론적 조성, 즉 Ca/P 비가 1.62 또는 1.72인 시편에서 두드러지게 나타났다. 주목할만한 것은, 용해가 진행되는 동안 세라믹스의 표면에는 골식세포의 흡수 과정에서 흔히 볼 수 있는 표면 결함(lacunae)과 매우 유사한 모양을 갖는 원형의 빈 공간(cavity)이 형성되었다. Hydroxyapatite (HA) ceramics with the Ca/P ratios of 1.62, 1.67 and 1.72 were prepared and their dissolution behaviors in distilled water at $37^{\circ}C$ were investigated. It appeared that surface dissolution of the ceramics was initiated from grain boundaries after 3 days of immersion in water. Following 10 days of immersion, microstructural disintergration of HA was severs for non-stoichiometric compounds, I.e Ca/P ratios of 1.62 and 1.72. Notably, a micron-sized circular cavity similar to lacunae, which can be generally formed in osteoclastic resorption process, was observed.
-
상용 인산칼슘계 분말로 제조된 생체세라믹스의 표면용해 특성
서동석,김환,이종국,Seo D. S,Kim H,Lee J. K 한국재료학회 2004 한국재료학회지 Vol.14 No.1
In this study, dissolution characteristics of four types of commercial calcium phosphate ceramics were investigated in distilled water with respect to chemical composition and microstructure. For all samples, no significant damage was observed after 3 days of immersion. Following the 7 days of immersion, surface dissolution of the ceramics containing a crystalline phase susceptible to water such as TCP, even pure hydroxyapatite, was initiated at grain boundaries and the dissolution was extended interior to the material along the grain boundaries. In the considerably dissolved area, there was grain separation followed by the formation of 20 $\mu\textrm{m}$ of cavities. In at least one case, the residual pores on the surface appeared to initiate dissolution. In a dissolved area, a crack during the fracture propagates along the grain boundaries resulting in intergranular fracture, while transgranular fracture occurs in a dense area without significant dissolution.
-
서동석,이종국,김환,Seo, Dong-Seok,Lee, Jong-Kook,Kim, Hwan 한국세라믹학회 2000 한국세라믹학회지 Vol.37 No.7
Titanium hydroxide precipitate was obtained by the reaction of 0.5M TiOCl2 and 5M NH4OH solutions, then anatase TiO2 powder with nanotubes was prepared by the digestion of the heat-treated powder in 5M NaOH solution. Nanotube was formed for anatase TiO2 powder digested at 10$0^{\circ}C$ above, and the amount and length of nanotube increased with the digestion temperature. In the case of the powder digested at 15$0^{\circ}C$ for 12h, the formed nanotube was 100~150nm in length, 10~20 nm in diameter, and 2nm in width of the walls on both sides of the nanotube. The powder digested at 15$0^{\circ}C$ for 12h showed the highest specific surface area of 270$m^2$/g.
-
-
徐東錫 亞洲大學校 1983 論文集 Vol.6 No.-
This paper has sought to determine the factors impacting on the growht of loan of foreign banking branch in Korea. It was hypotesized that six factors could be expected to determine this growth: the volume of trade, the size of Korea domestic market, the credit condition of Korean financial market (host country), the credit condition of home countries, the seasonal variable, and the changes of economic policy in host country affecting the level of loan of foreign banking branch. The empirical results suggested that these factors tended to impact on the loan activity of Korean branches of U.S. banks in a different manner from Korean officies of Japanese banks, with the loan pattern of multinational banks from the U.S.A. more affected by their credit conditions of home countries and less concerned with credit conditions of the host country. The export volume of host country appeared to have a negative effect on the underlying growth of loan of the Japanese multinational banks while U.S. based multinational banks had been relatively unaffected.
-
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
