플랜트 건설공사의 벤더관리 발전방향 기초연구

박환표 ( Park Hwan-pyo ),한재구 ( Han Jae-goo ),진경호 ( Chin Kyung-ho ) 한국건축시공학회 2011 한국건축시공학회 학술발표대회 논문집 Vol.11 No.2

반건양건 단일 4가닥을 이용한 전방십자인대 재건술의 중기 추시 결과

박호원(Ho-Won Park),김희준(Hee-June Kim),경희수(Hee-Soo Kyung),한정원(Jung-Won Han) 대한정형외과학회 2015 대한정형외과학회지 Vol.50 No.5

목적: 반건양건 단일 4가닥을 이용하여 단일 다발 전방십자인대 재건술을 시행한 후 중기 추시 결과를 조사했다. 대상 및 방법: 2006년 6월부터 2009년 6월 사이 경북대학교병원에서 반건양건 단일 4가닥을 이용한 단일 다발 전방십자인대 재건술을 시행받은 81명 84예에 대해 분석하였다. 평균 나이 28.8세, 수상 후 수술까지의 기간은 평균 9개월, 평균 추시 기간은 72개월이었다. 임상적 평가로 Lachman 검사, pivot-shift 검사, KT-2000 관절계 검사, Lysholm 점수, Tegner 활동점수, International Knee Documentation Committee (IKDC) 주관적 점수, 수상 전 운동 상태로의 복귀를 조사하였고, 방사선 검사로 관절 간격 협소 등을 관찰하였다. 결과: 전체 예에서 관절 운동범위는 정상으로 회복됐고, Lachman 검사 양성 4예, pivot-shift 검사 양성 3예, Lysholm 점수 92.2점, Tegner 활동점수 6점, IKDC 주관적 점수 86.5점, KT-2000 관절계 계측상 건측과 2.3 ㎜ 차이, 수상 전 활동으로 복귀가 80.2%였다. 방사선적 관절간격의 변화는 수술 전, 후 의미 있는 차이는 없었다. 결론: 반건양건 단일 4가닥을 이용한 단일 다발 전방십자인대 재건술 후 중기 추시 결과 관절의 안정성이 유지되며 임상적으로 만족할 만한 결과를 얻었다. Purpose: The purpose of this study was to evaluate the mid-term results after anterior cruciate ligament (ACL) reconstruction using a single four-strand semitendinosus tendon. Materials and Methods: We evaluated 81 patients (84 cases) who had undergone ACL reconstruction using an autologous single four-strand semitendinosus tendon. The patients consisted of 77 men and 4 women with a mean age of 28.8 years (15-59 years) years. Most injuries were sports related, and the largest number of cases occurred during a soccer game (38 cases). Combined injuries were meniscus injuries in 43 cases, cartilage injuries in 6 cases and medial collateral ligament injuries in 8 cases. Femoral fixation device was PINN-ACL CrossPin in 44 cases and extracortical suspension device in 40 cases. Suture tie around a screw post and an additional bioabsorbable screw were used for tibial fixation. The mean time from injury to surgery was 9±16 months (7 days-10 years) and the mean follow-up period was 72.0±8.3 months (53-95 months). Clinical evaluation was performed using Lachman test, pivot-shift test, KT-2000 arthrometer, Lysholm score, Tegner activity score, International Knee Documentation Committee (IKDC) score and return to pre-injury sports activity. Radiologic evaluation was performed using plain radiographs to evaluate joint space narrowing. Results: All patients showed normal range of motion at the final follow-up. The Lachman test was positive in 4 cases, and pivot-shift test was positive in 3 cases. Lysholm score improved from 76.7 to 92.2, Tegner activity score improved from 5.1 to 6, IKDC score improved from 72.0 to 86.5, and mean anterior translation by KT-2000 improved from 7.4 mm to 2.3 mm, and 80.2% of patients returned to pre-injury sports activity. No significant differences in joint space narrowing were observed in plain radiographs. Conclusion: In this study, good results were obtained after ACL reconstructions using the autologous four-strand single semitendinosus tendon with maintaining the joint stability at mid-term follow-up.

건축표준설계기준 재료시공분야 (KBC-MC)의 건축재료 설계기준에 관한 연구

박원준(Park, Won-Jun),신준호(Shin, Jun-Ho),하지연(Ha, Ji-Yeon),나경욱(Na, Kyung-Uk),성명진(Sung, Myung-Jin),이한승(Lee, Han-Seung) 대한건축학회 2013 대한건축학회 학술발표대회 논문집 Vol.33 No.1

액체 로켓 엔진에 있어서 추진제 공급 선점 시간에 따른 점화 특성에 관한 연구

박정,김용욱,김영한,이재룡,정용갑,조남경,오승협,Park, Jeong,Kim, Yong-Wook,Kim, Young-Han,Lee, Jae-Yong,Chung, Yong-Gahp,Cho, Nam-Kyung,Oh, Seung-Hyub 대한기계학회 2000 大韓機械學會論文集B Vol.24 No.11

Experimental studies on determination of the supply leading time of propellants to combustion chamber have been made to stably and efficiently guarantee the ignitions process with liquid rocket engine. The propellant used is a Kerosene as fuel and a liquid oxygen as oxidizer. FOOF type of three injectors are set with an angle of 135。 and the combustion chamber pressure is 200psi. The present experiment program also includes the stability on the quadlet type of ignitor using the triehylaluminum (TEAL) as an ignition source. Experimental results clarifies that the propellant supply through LOx leading to combustion chamber is proper for stable ignition and combustion processes based on the fuel and oxidizer manifold pressures, combustion chamber pressure, and the variation of flame length from the nozzle exit with lapse time, and shows that the leading supply time pf propellants effects the engine performance little.

Benign Epilepsy of Childhood with Centrotemporal Spikes

박원일(Wonil Park),한상주(Sang Ju Han),이홍진(Hong Jin Lee),이경자(Kyung Ja Lee) 대한소아신경학회 1993 대한소아신경학회지 Vol.1 No.2

Objective. To identify the short-term prognostic factor, and also assess the clinical and EEG changes following treatment. Patient and Method. We reviewed the medical record of 24 patient who followed up more than 12month, and compared seizure control rate as a pedictor according to sex, age at onset, seizure type, ferequency. BECCT was diagnosed as following criteria: 1) nocturnal seizures or hemifacial seizure on wakening state, 2) normal intelligence and no abnormal neurologic sign, 3) normal EEG background activity with monomorphic sharp or spike acticity which increase the frequence during sleep if sleep EEG was available. Result. 1) Age at onset was range from 3 years to 11 years (7.1±1.9) and Patient were followed up from 12 month to 92 months.(34.8±25.1) 2) Seizure was free in 54.2% of patients 1 month after therapy, in 75.0% 6 month after, in 83.3% 1 year after, in 95.8% 2 year after. We found that seizure frequence before treatment was the most important predictor ( P < 0.05 ), and also found that male, older age at onset had more fovorable outcome of prognosis during follow up. 3) Partial seizures were increased from 54.2% before therapy to 83.2% after therapy and seizure pattern tend to become localized to the face.( P < 0.05). 4) Epileptiform discharge did not disappear from the EEG during short-term follw up. Conclusion. Although BECCT recurred frequently during short-term follow, BECCT has not only an excellent long term prognosis bu also mild seizure localized to the face following treatment. It would be better to avoid heavy dose of AED or polytherapy, and we found the age onset, frequence of seizure as predictor of the seizure relapse.

Effects of Gamma-Irradiation on the Sterilization of Primordial Germ Cells in Quail

Kyung Je Park(박경제),Tae Min Kim(김태민),Hyung Chul Lee(이형철),Hyun-Jun Jang(장현준),Gwonhwa Song(송권화),Jae Yong Han(한재용) 韓國家禽學會 2010 韓國家禽學會誌 Vol.37 No.2

조류의 원시생식세포는 수용체 배자로의 주입을 통해서 생식선 카이메라 생산을 가능하게 하기 때문에 유전자 도입에 매우 효율적인 도구이다. 특히, 메추리는 성성숙이 빠르며 산란능력이 뛰어 나기 때문에 형질전환 조류 생산과 유전자 기능 연구에 매우 적합하다. 형질전환 조류 생산 효율을 높이기 위해서는 수용체 배자 내의 원시생식세포의 수를 줄이는 것이 필수적인 요소이지만, 아직까지 메추리에서 이러한 시도를 했다는 보고는 없다. 본 연구는 감마선 조사가 수용체 내의 원시생식세포의 수를 감소시킬 수 있는지 알아보았다. 먼저 0, 250, 500, 750, 1,000 rads 강도의 감마선을 갓산란된 메추리알에 조사 후 5일령 배자에서 기형 발생빈도를 측정하였고, 0과 500 rads에서 17일째 부화율을 검정하였다. 그리고 500 rad의 감마선을 산란된 알에 73초간 조사 후 5일간 배양시킨 뒤 원시생식세포의 수를 측정하였다. 그 결과, 1×10⁴개의 세포 당 원시생식세포의 수는 수컷은 107.75±3.96에서 80.30±4.34로, 암컷에서 99.56±3.22에서 81.67±3.72로 원시생식세포수가 감소되었다. 이상의 연구 결과는 감마선 조사가 수용체 배자내의 원시생식세포를 감소시킬 수 있고, 이를 형질 전환 기술에 접목시켜서 생식선 카이메라 효율을 높일 수 있는 가능성을 보여 주고 있다. Quail is a very useful animal model for studying vertebrate development because of its small body size and unique reproductive traits. This species is also ideal model for producing germline chimeras via transferring exogenous primordial germ cells (PGCs) into the recipient embryo. To increase the contribution efficiency of donor PGCs into recipients’ tissues, decreasing the population of endogenous PGCs has been rate-limiting factor. We therefore conducted this study to investigate if gamma (γ)-irradiation depletes endogenous PGCs in developing quail embryo. Firstly, freshly laid stage X quail embryos were irradiated with various output of γ-irradiation and its teratogenic effect on the embryo was evaluated. Although a dose-dependent increase in the number of embryo showing malformation was found as the output increased (0, 250, 500, 750, and 1,000 rads), only a maximum of 10.1% of embryos were abnormal in 1,000 rads. Immunocytochemical analysis using the QCR1 antibody, which is specific marker for quail PGCs, was conducted to analyze the effect of sterilization. As results, γ-rays at a dose-rate of 500 rads/73 sec onto undeveloped stage X embryo significantly reduced the number of germ cells to an average of 75.55 % and 82.03 % in male and female embryos, respectively. We conclude that γ-ray selectively targets PGCs while affects minimally to the somatic development in quail embryo. Our results will not only provide important data for germline chimera production but can be used for analyzing the effect of ionized rays on the differentiating germ cells in various stages during animal development.

전문가치면세정술과 세균막관리교육의 임플란트 주위염 감소 효과

박경화 ( Kyung Hwa Park ),한경순 ( Gyeong Soon Han ) 한국치위생과학회 2012 치위생과학회지 Vol.12 No.2

The purpose of this study was determine the effects of professional tooth cleaning and plaque control instruction(PT & PCI) on reduction of peri-implantitis. A total 80 implant patients were investigated using O`Leary plague index(PI), Loe & Silness gingival index(GI), implant bone loss(BL). While the PT & PCI was conducted by using ``Watanabe method`` after scaling for the experimental group, the engine polishing and a plaque control instruction was operated by rolling method after scaling for the control group. The collected data were analyzed with t-test, ANOVA, paired t-test and stepwise multiple regression. PI and GI of the experimental group significantly decreased than the control group(p<0.05). BL, also tended to decreased in the experimental group than the control group(p=0.155). Multiple regression analysis, the factors that was highly correlated with PT & PCI on the PI and GI. According to the implant characteristics, implant location and duration were closely related to PI(p<0.05). Therefore, the PT & PCI is one of the effective methods to reduce the failure caused by the peri-implantitis. Based on this conclusion, that it would be meaningful if the proposed PT & PCI is applied to the oral health management programs of the implant patients.

의과대학생의 의학교육 및 의료에 대한 의식 조사

박정한(Jung Han Park),김경환(Kyung Hwan Kim),전혜리(Hae Ri Jun),이주영(Ju Young Lee) 한국의학교육학회 1999 Korean journal of medical education Vol.11 No.2

1983년에 전국 규모의 의대생들에 대한 의식 및 가치관 조사를 실시한 이래 그동안 의대 수와 학생정원이 약 2배 증가하였고 사회․경제적 여건도 많이 변하였으므로 의대생들의 의식과 가치관이 어떻게 변하였는지 알아보기 위하여 이 조사를 다시 실시하였다. 1997년 11월 당시 전국의 40개 의대가운데 의학과 4학년까지 재학생이 있는 32개 대학의 의학과 재학생 전원을 모집단으로 하여 각 학년별 학생명부의 출석번호를 이용하여 10명에 1명씩 계통표본추출을 하고, 각 학년의 출석번호 끝번을 추가한 표본을 대상으로 설문조사를 하였다. 설문지는 1983년에 사용한 것을 근간으로 하여 최근 의료환경 변화에 대한 내용과 의대생들의 의학 및 직업관 형성에 관련된 문항을 추가하여 개발하였다. 조사는1997년 12월에서 1998년 1월 사이에 각 대학마다 사전에 위촉된 1명의 조사담당 교수가 조사대상자들에게 설문지를 배부하여 기입하게 하였다. 총 재학생 11,987명중에 설문 조사대상으로 뽑힌 1,386명가운데 1,233명 (89.0%)이 응답하였는데 응답자중 학년 미상 11명과 응답이 부실한 1명을 제외한 1,221명을 최종 분석대상으로 하였다. 몇 가지 특성을 중심으로 모집단과 조사표본을 비교해 본결과 표본의 대표성에는 별 문제가 없었다. 조사내용을 3부분으로 나누어 보고하였는데 1부에서는 조사방법과 조사대상자의 특성 및 응답자들의 의학교육에 대한 태도와 의학에 대한 본인의 적성에 관해 기술하였다. 응답자중 남자가 75.7 %를 차지하였다. 고졸 즉시 의대에 입학한 학생의 비율은 서울지역이 45.8 %, 서울 이외지역은 53.4 %이었다. 본인의 정치적 성향이 보수적이라는 사람이 서울지역은 43.9 %, 서울 이외 지역은 33.0 %로 지방 학생들이 진보적이라는 응답률이 더 높았다. 종교를 가진 사람이 57.2 %이었는데, 기독교가 31.0 %, 가톨릭 15.2 %, 불교 9.5 % 순이었다. 아버지의 교육수준이 대학 또는 그 이상인 사람이 59.8 %로 일반 국민의 교육수준보다 높았다. 아버지의 직업분포도 전문직 21.2%, 회사원 17.2%,공무원 13.1 %, 관리직 11.8 %, 의료인 8.7%로 화이트칼라가 지배적이었다. 의대진학 결정과정에 영향을 미친 사람이 있었다는 사람이 53.7 %이었는데, 이들중 부모가 62.1%를 차지하였다. 의대진학을 권유한 이유중 사회․경제적 측면이 33.5%로 가장 높은 비율을 차지하였다. 의학공부의 재미있는 측면은 생명현상을 배우는것 (47.2 %)과 인간을 배울 수 있다 (44.3%)는 것이었고, 재미없는 측면은 암기식 공부라는 것(39.7%)과 공부 분량이 너무 많다 (34.1%)는 것이었다. 만약 고교 3학년에 되돌아가 다시 대학을 선택할 경우 여전히 의대를 선택하겠다는 사람은 50.3 %이었으나, 지금 전과가 가능하다면 전과하겠다는 사람은 6.0 %에 불과하였다. 의학 공부에 자신의 적성이 맞다는 사람은 64.9%이었고, 이 비율은 학년이 올라갈수록 증가하였다. 장차 자기 아들을 의대에 보내겠다는 사람은 남학생중 36.6%, 여학생중 26.7%였고, 딸을 의대에 보내겠다는 사람은 각각 33.6%, 27.7%이었다. Since the first survey done in 1983, this is the second national sample survey of medical students about their perception and evaluation on medical study, career plan, and medical care system. One out of every 10 students plus one in each class were systematically sampled from each grade year of 32 medical schools in Korea that had students from freshman to senior in November 1997. A questionnaire was developed by adding items related with recent changes in medical care environment and with viewpoint on medicine and physician as an occupation to the questionnaire used in 1983. The questionnaire was administered at each school under the supervision of designated collaborator of the same school in December 1997 through January 1998. A total of 1,386 students were sampled from a total of 11,987 medical students and 1,233 students(89.0%) filled out the questionnaire. Twelve students were excluded from the analysis because of incomplete response and the final analysis was done for 1,221 students. A few demographic characteristics of the sample were compared with those of the study population to check the representativeness of the sample and found no skew. The contents of the study were divided into three parts and the first part describes the study methods, demographic and other characteristics of the sample, students viewpoint on medical education, and students aptitude for medicine Male students accounted for 75.7% of the sample. The proportion of students who entered medical school right after graduating from a high school was 45.8% in Seoul and 53.4% in other than Seoul area. The students who classified their own political inclination conservative were 43.9% in Seoul and 33.0% in other than Seoul and the percentage of students with progressive inclination was higher in out of Seoul than Seoul area. The proportion of students who have a religion was 57.2%; Christian 31.0%, Catholic 15.2%, and Buddhist 9.5%. The educational level of fathers of students was far higher than the level of general population, e.g. 59.8% had college or higher education. Occupation of fathers was mainly white-collar worker; professional worker 21.2%, company employee 17.2%, government official 13.1%, manager 11.8%, and medical professional 8.7%. In the decision-making process to enter the medical school, 53.7% of the students were influenced by someone else and 62.1% of them were parents. Socio-economic factor was the most common reason for recommending medical school and it accounted 33.5% of the reasons. Medical students enjoy learning life phenomenon(47.2%) and human being(44.3%) in medical study but most disturbing factors are memory work(39.7%) and too much to study(34.1%). If students were given another chance to choose a college as a senior student in high school, 50.3% of them said that they would choose medical school. Only 6% of students have intention to change their major subject of study if they are allowed to change now. The proportion of students who consider their scholastic aptitude is compatible with medical study was 64.9% and such proportion increased with grade. The percentage of students who are going to recommend medical school to their own son in the future was 36.6% for male and 26.7% for female students and to their own daughter 33.6% and 27.7%, respectively.

In vitro Culture of Dendritic Cells and Activation of Peripheral Mononuclear cells in Patients with Chronic Myelogenous Leukemia

박석영 ( Suk Young Park ),김기원 ( Kee Won Kim ),한지연 ( Ji Youn Han ),강진형 ( Jin Hyung Kang ),홍영선 ( Young Seon Hong ),김훈교 ( Hoon Kyo Kim ),김춘추 ( Chun Choo Kim ),이경식 ( Kyung Shik Lee ) 대한내과학회 1999 대한내과학회 추계학술대회 Vol.57 No.-

Doxorubicin에 과민반응을 보인 유방암 환자에서 성공적으로 시행한 Epirubicin 탈감작 요법

박한기 ( Han Ki Park ),김민혜 ( Min Hye Kim ),임경환 ( Kyung Whan Lim ),강민구 ( Min Koo Kang ),김병근 ( Byung Keun Kim ),김태완 ( Tae Wan Kim ),권재우 ( Jae Woo Kwon ),이소희 ( So Hee Lee ),이상민 ( Sang Min Lee ),김세훈 ( Se Hoo 대한천식알레르기학회 2009 천식 및 알레르기 Vol.29 No.2

Doxorubicin, a chemotherapeutic agent of the anthracycline family, has commonly been used to treat a wide range of cancers including leukemia, Hodgkin`s lymphoma, and cancers of the breast, uterus, ovary and bladder. Hypersensitivity is a rare adverse reaction to anthracyclines including daunorubicin, idarubicin and epirubicin. Although cross-reactivity among chemotherapeutic agents of the anthracycline family is not completely established, these agents are not clinically recommended if a patient has show hypersensitivity reaction to any anthracyclines. Desensitization is an alternative treatment option to overcome hypersensitivity reaction to anthracyclines, but cases of anthracycline desensitization have rarely been reported till now. We report successful epirubucin desensitization in a breast cancer patient with doxorubicin hypersensitivity. (Korean J Asthma Allergy Clin Immunol 2009;29:127-131)