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- 주제어 : cefazedone (검색결과 1 건)
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산부인과 영역에서 감염증에 대한 치료로서 Pazeron의 유효성과 안전성을 평가하기 위한 제 4상 임상시험
김재욱(Jae Wook Kim),최은경(Eun Kyoung Choi),박용원(Yong Won Park),김영태(Young Tae Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.9
Objectives: This study was planned to evaluate the clinical efficacy and safety of cefazedone in the treatment of patients with infectious disease in the field of obstetrics and gynecology. Method: Cefazedone was used in 20 patients with infectious disease in obstetrics and gynecology, who visited the department of obstetrics and gynecology, Yonsei university college of medicine, from June 1998 through July 1999. Results : The mean age of the patients was 42.5 years(range of 18 to 68 years) and 17 of patients were diagnosed as pelvic inflammatory disease(PID), 2 were urinary tract infection due to huge ovarian tumor, and 1 was Bartholin's gland abscess. Cefazedone was proven its efficacy in treating infections of obstetrics and gynecology so as to reach 100% of response rate. The cefazedone was sensitive to all isolated organisms - G. vaginalis, E. coli, Staphylococcus, coagulase (+), etc. In the course of treatment, 1 patient experienced mild nausea, another 1 patient complained mild diarrhea, and another 1 patient showed transient leukopenia but their symptoms and signs were disappeared with only conservative management. There was no significant renal and hepatic function changes. Conclusion : Our results suggest that cefazedone is relatively effective in treating infections of obstetrics and gynecology to show excellent antibacterial effects and low incidence of complications.
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