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- 주제어 : Postoperative remnant gastritis (검색결과 1 건)
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수술 후 잔위에서 Helicobacter pylori의 분포와 역할
최윤종 ( Yeun Jong Choi ),김현수 ( Hyun Soo Kim ),박동훈 ( Dong Hoon Park ),김문영 ( Moon Young Kim ),백순구 ( Soon Koo Baik ),이동기 ( Dong Ki Lee ),권상옥 ( Sang Ok Kwon ),박광화 ( Kwang Hwa Park ) 대한소화기학회 2003 대한소화기학회지 Vol.41 No.3
Background/Aims: The distribution of Helicobacter pylori (H. pylori) and its effect on postoperative remnant gastritis has not been clearly investigated. Thus, we carried out this study to examine H. pylori positive rate in the body and cardia and to assess the role of H. pylori on the pathogenesis of remnant gastritis. Methods: Eighty-two patients who had undergone gastric surgery (Billroth I, II) were studied. Four biopsy specimens were obtained from the cardia and oral side of anastomosis for histological analysis and CLO test. The histological grades of gastritis were determined by four parameters of visual analogue scales adopted by updated Sydney system. Results: The overall positive rate of H. pylori was 48.8%. Among the infected patients, H. pylori positive rate was significantly higher in the cardia than in the body (87.5% vs. 37.5%, p< 0.01). The H. pylori positivity was not associated with age, sex, primary disease, type of surgery, chemotherapy, and postopertive interval. The gastritis scores of inflammatory cell infiltration were higher in H. pylori positive patients. However, the scores of atrophy and intestinal metaplasia were not significantly different between the two groups. Conclusions: The H. pylori positive rate is higher in the cardia than in the body of postoperative remnant stomach. It suggests that H. pylori may play an important role in remnant gastritis through acute and chronic inflammatory cell infiltration. (Korean J Gastroenterol 2003;41:177-182)
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