유산소성 운동과 저항성 운동의 실시 순서가 지방대사 및 동화작용 호르몬에 미치는 영향

윤성진(Sung Jin Yoon),서경호(Kyoung Ho Seo),박해찬(Hae Chan Park),강민정(Min Jeong Kang),전정희(Joung Hee Jon),변용현(Yong Hyun Byun) 한국사회체육학회 2013 한국사회체육학회지 Vol.0 No.53

The purpose of this study is to investigate the effects of sequence of aerobic and resistance exercise on free fatty acids, epinephrine, testosterone, and IGF-1. 7 healthy adult males, the subjects of this research, performed both resistance exercise after aerobic exercise and aerobic exercise after resistance exercise. V?O2max of all the subjects was measured through treadmil test, and they performed aerobic exercise for 30 minutes using treadmil at the intensity of 65% of V?O2max. They also performed resistance exercise using weight machine. They did 80%1RM × 8~10 rep × 3set with one-minute rest between each set. Resistance after aerobic subjects had their blood sample all 4 times: before aerobic exercise, after aerobic exercise, after resistance exercise, and at 30-minute in the recovery; The aerobic after resistance subjects did their blood sample all 4 times: before resistance exercise, after resistance exercise, after aerobic exercise, and at 30-minute in the recovering period. Data were analyzed using SPSS PC 20.0. The Data were analyzed by One-way repeated ANOVA. Scheffe were used as a Post-Hoc test. Statistical significance level was a=.05. As a result of this study are as follows. First, the FFA are significant for resistance exercise after aerobic exercise group(p=.028). That is, FFA significantly increased after aerobic exercise and then decreased during 30-minute in the recovering stage; the coefficients on FFA are not significant for aerobic exercise after resistance exercise group(p=.415). Second, the coefficients of epinephrine are significant for resistance exercise after aerobic exercise group(p=.012); increased epinephrine resistance after exercise decreased during 30-minute in the recovering stage; the coefficients of epinephrine are not statistically significant for aerobic exercise after resistance exercise group(p=.112). Third, testosterone are significant for aerobic exercise after resistance exercise group(p=.004); increased testosterone due to resistance exercise decreased after aerobic exercise during 30-minute in the recovering stage. However, we can see that the coefficients of testosterone are not statistically significant in case of resistance exercise after aerobic exercise group(p=.074). Fourth, we can find that the coefficients on IGF-1 are statistically significant for both aerobic after resistance exercise(p=.000) and resistance exercise after aerobic groups(p=.000); the coefficients on IGF-1 are not significant after aerobic exercise, but they are significantly increased after resistance exercise for both. In conclusion, resistance exercise after aerobic exercise is likely to have a significant effect on FFA and epinephrine; aerobic exercise after resistance exercise look to affect testosterone and IGF-1. Accordingly, based on the research findings we can find that it is important to decide the order of exercise between aerobic exercise and resistance exercise depending on the purposes fat metabolism or protein synthesis of exercise.

저항운동과 유산소성 운동 순서에 따른 복합운동이 건강관련체력, 에너지기질에 미치는 영향

고영찬(Yeong Chan Ko),김영표(Young Pyo Kim) 한국사회체육학회 2012 한국사회체육학회지 Vol.0 No.48

The purpose of this study was attempted to to identify the effects of combined resistance exercise and aerobic exercise course on health-related, and energy substrates. This study divided 24 healthy college students into the group of aerobic exercise after resistance exercise(n=8), the group of resistance exercise after aerobic exercise(n=8), and the control group(n=8) and thereby conducted a combined exercise program of different order for 12 weeks. Resistance exercise was conducted 4 times a week with the intensity of 60~70% of 1RM during the 1st through 8th week and the intensity of 70~80% of 1RM during the 9th through 12th week. Aerobic exercise was conducted 4 times a week with the intensity of 60~70% of maximum heart rate during the 1st through 8th week and the intensity of 70~80% of maximum heart rate during the 9th through 12th week. The results are as follows. 1. Changes of the health-related physical fitness In the changes of body composition through which we can know the degree of obesity. Body fat significantly decreased in both groups after 8 weeks and the decreased values were similar in each other group. However, the group of aerobic exercise after resistance exercise showed a significant increase of LBM after 8 weeks. We think that the method of aerobic exercise after resistance exercise was more effective than the other type of program. In the changes of physical fitness, flexibility, muscular endurance, muscular strength, and cardiovascular endurance of both exercised groups significantly increased compared to a control group. However, the increased values in both exercised groups showed similar results. 2. The changes of energy substrates There were no significant differences in glucose and free fatty acid being used by elements of energy substrates between the group of aerobic exercise after resistance exercise and the group of resistance exercise after aerobic exercise. Lactic acid, however, significantly decreased in the group of aerobic exercise after resistance exercise(0>12 weeks) and in the group of resistance exercise after aerobic exercise (0> 8, 12 weeks) compared to control group, respectively. Ultimately, this study provides evidence that the program which conducted aerobic exercise after resistance exercise is more effective than the program which conducted resistance exercise after aerobic exercise in the aspect of improving body composition. However, the both exercised groups showed a similar effect regardless of the order of execution of exercise in the elements of physical fitness and energy metabolism.

Six weeks of combined aerobic and resistance exercise using outdoor exercise machines improves fitness, insulin resistance, and chemerin in the Korean elderly: A pilot randomized controlled trial

Kim, Dong-Il,Lee, Dong Hoon,Hong, Sunghyun,Jo, Sung-won,Won, Young-shin,Jeon, Justin Y. Elsevier 2018 ARCHIVES OF GERONTOLOGY AND GERIATRICS Vol.75 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>The aim of this study was to investigate the effect of a six-week-long exercise program using outdoor exercise equipment on fitness, insulin resistance and adipocytokines among Korean elderly.</P> <P><B>Methods</B></P> <P>A total of 47 participants were randomized into one of the following three groups; control, resistance exercise or combined exercise (aerobic and resistance exercise). The resistance exercise group completed three resistance types of exercise. The combined exercise group completed five exercises, including three resistance types of exercise and two aerobic types of exercise. Participants’ body composition, fitness level, homeostasis model assessment of insulin resistance (HOMA-IR), and adipocytokines were measured at baseline and at the end of six weeks.</P> <P><B>Results</B></P> <P>After six weeks of exercise training, participants in the combined exercise group exhibited significant reduction in insulin, HOMA-IR and chemerin levels, while significant reduction was observed in HOMA-IR only in the resistance exercise group compared with the control group. Meanwhile, six weeks of exercise training, whether resistance exercise alone or combined, significantly improved upper body muscular strength/endurance and physical function compared to the control group.</P> <P><B>Conclusions</B></P> <P>Six weeks of combined exercise using outdoor exercise equipment was effective in improving fitness, HOMA-IR, circulating chemerin levels, and other known risk factors of chronic diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> This is the first study to objectively estimate the effects of exercise using outdoor exercise machine for elderly people in Korea. </LI> <LI> We investigated feasibility of the exercise using outdoor exercise machine in a pilot RCT. </LI> <LI> Combined exercise using outdoor equipment may offer greater benefits than resistance exercise alone. </LI> </UL> </P>

대사증후군 중년 여성의 12주간 저항운동시 운동강도에 따른 대사증후군 위험인자에 미치는 영향

김정훈(KimJung-hun),이한준(LeeHan-joon) 한국체육학회 2017 한국체육학회지 Vol.56 No.2

이 연구는 대사증후군 중년여성에게 12주간 저항운동 강도의 차이가 대사증후군 위험인자에 미치는 영향을 검증하는데 목적이 있다. 본 연구의 피험자는 U시 지역 건강 보험공단 건강증진센터 운동프로그램에 참여한 사람 중 대사증후군 진단기준에 의거하여 대사증후군 판정을 받은 대상자 중 중년여성 80명을 네 집단(저강도 운동군, 중강도 운동군, 고강도 운동군, 대조군)으로 각각 나누어 무선배치 하였다. 탈락자를 제외하고 각 집단별 12명이 최종적으로 연구를 수행하였다. 본연구의 운동강도는 사전에 1RM을 측정 한 후 저강도(40%1RM), 중강도(70%1RM), 고강도(90%1RM)로 12주간 주 5회씩 집단별 저항 운동 프로그램을 실시하였다. 저항운동 전·후 측정항목은 대사증후군 위험인자로 허리둘레, 혈압, 혈당, 중성지방과 HDL-C를 측정 하였다. 본 연구의 자료처리는 SPSS/ver 18.0을 이용하여 측정 항목별 평균(M)과 표준편차(SD)를 산출하였다. 집단간 차이검증은 집단간의 사전 값의 차이가 있기 때문에 사전검사 값을 공변량(covariate)으로 한 공분산 분석(ANCOVA)으로 분석하였고, 통계적으로 유의할 경우 사후검증으로 LSD를 실시하였고, 유의수준은 α= .05로 설정 하였다. 본 연구 절차를 통해 얻은 결론은 저항운동은 허리둘레, 이완기혈압, 혈당에 긍정적인 영향을 주었으며, 운동강도는 중강도(70%1RM)가 저강도(40%1RM)나 고강도(90%1RM)보다 효과가 더 크다고 결론내릴 수 있다. The purpose of this study was to examine the effects of resistance exercise intensity on the risk factors of metabolic syndrome in middle-aged women who suffer from metabolic syndrome. This study selected 80 middle-aged women who participated in exercise program at the Health Center of the National Health Insurance Corporation U City Branch Office and randomly assigned them into 4 groups, which are control group(n=12), low intensity resistance exercise group(n=12), moderate intensity resistance exercise group(n=12), and high intensity resistance exercise group(n=12). The exercise intensity of this study was conducted within at 40% of 1RM by the low intensity resistance exercise group, at 70% of 1RM by the moderate intensity resistance exercise group, and at 90% of 1RM by the high intensity resistance exercise group after measuring their 1RM. The program was designed to do resistance exercises 5 times a week for 12 weeks among the groups. The risk factors of metabolic syndrome (waist circumference, blood pressure, blood sugar, TG, HDL-C) was measured before and after the resistance exercise. In terms of data, the mean and the standard deviation of each measurement item were calculated by using SPSS ver. 18.0, and the ANCOVA that used the value for the pre-test as a covariate was chosen because there was a difference among groups. Post-verification of LSD was conducted when there is a statistically significant difference. The level of significance was decided at α = .05. The conclusion obtained from this study indicated as follows. The risk variables of metabolic syndrome, waist circumference, diastolic pressure, blood glucose had an effect on resistance exercise. And the moderate intensity(70%1RM) resistance exercise was more effective than low intensity(40%1RM) and high intensity(90%1RM) resistance exercise.

자연과학편 : 저항성 운동과 고단백식이가 중년 흰쥐 골격근의 TLR-4 단백질 활성에 의한 내재면역기능에 미치는 영향

안나영(NaYoungAhn),김상현(SangHyunKim),김기진(KiJinKim) 한국체육학회 2015 한국체육학회지 Vol.54 No.4

본 연구의 목적은 저항성 운동과 고단백식이가 흰쥐 골격근의 내재면역 반응과정에서 TLR-4 단백질 활성 및 염증성 사이토카인 발현에 미치는 영향을 분석하는데 있다. 연구대상은 50주령 Wistar계 중년 수컷 흰쥐 50마리를 4주간 고지방식이로 비만을 유도한 후 5집단(High fat diet+Control, High fat diet+High fat diet, High fat diet+High protein diet, High fat diet+High fat diet+Resistance exercise, High fat diet+High protein diet+Resistance exercise)으로 구분하였다. 그 후 8주간 그룹에 따라 고지방식이, 고단백식이 및 저항성 운동(사다리 운동, 체중의 70~100% 부가, 8회/세트, 8세트, 3일/주) 처치를 병행하였다. 8주간의 식이 처치 및 저항성 운동 후 골격근을 적출하여 분석하였다. 연구결과 8주간의 고지방식이 그룹에서 저항성 운동 후 인슐린 저항성, TLR-4 단백질 활성, IL-1β 및 IL-6의 발현이 감소하였으며, 고단백질 식이 그룹에서는 TLR-4 및 IL-6에서 저항성 운동의 효과가 나타났다. 그러므로 저항성 운동은 골격근 기능을 강화시켜 내재면역기능을 높이는 것으로 생각되지만 세포표면에서의 내재면역의 신호전달기전에 대한 추후 연구가 필요할 것으로 생각된다. The purpose of this study was to investigate the effects of resistance exercise and high-protein diet treatment on innate immune function by TLR-4 protein activation and pro-inflammation cytokines on skeletal muscle of middle aged rat. 50-week middle aged male Wistar rats were given a 4-week high-fat diet to induce obesity before randomly assigning them into 5 groups (High fat diet+Control, High fat diet+High fat diet, High fat diet+High protein diet, High fat diet+High fat diet+Resistance exercise, High fat diet+High protein diet+Resistance exercise). Combinations of high fat diet, high protein diet, and resistance exercise (ladder climbing) treatments were administered. The groups with added resistance exercise were trained for 8 weeks with workout intensity, duration, and frequency of 70~100% body weight, 8rep/set, 8set, 3day/week respectively. After 8 weeks of diet treatment and resistance exercise, rats were sacrificed and skeletal muscle were dissected for analysis. Results showed insulin resistance, TLR-4 protein activation, IL-1β and IL-6 expressions significantly decreased after resistance exercise in the HF group. On the other hand, TLR-4 and IL-6 expressions of rats in the HP group also decreased following resistance exercise. Therefore, resistance exercise is believed to improve the innate immune system particularly in enhancing skeletal muscle function but further studies are needed to understand the cell surface’s innate immune pathway.

저항운동강도가 일반여성의 염증인자 및 CK에 미치는 영향

고성경(Ko, Seong-Kyeong),권영우(Kwon, Yeung-Woo) 한국체육과학회 2012 한국체육과학회지 Vol.21 No.4

The purpose of this study was to investigate the effect of different resistance exercise intensity on blood inflammatory factors(TNF-α, IL-6, CRP) and CK concentrations on women. Thirty female subjects(age 28.1±5.77years, weight 61.3±5.41㎏) were randomly assigned to high(3-5RM) and low resistance exercise(9-11RM). The high resistance exercise group performed four sets at 3-5RM with 3min rest between sets and the low resistance exercise group performed three sets at 9-11RM with 2min rest. Resistance exercise composed of seated bench press, pull down, back extension, sit up, leg curl, leg press, calf raise. Venous blood samples were taken from an antecubital vein by venepuncture and were collected at pre-exercise, immediate post-exercise and recovery period(24hours later). Blood TNF-α, CK concentration increased significantly immediately after exercise and such increase continued during recovery period in both treatment. Blood CRP concentration increased significantly after immediate exercise and recovery period. Especially such exercise induced increase of CRP is more higher in high intensity group than in low intensity exercise group. In conclusion acute resistance exercise increased blood inflammatory indices and muscle damage. Especially high intensity exercise resulted increased inflammatory response. Further study needed to elucidate the exact mechanism related to reactive oxygen response and regular resistance exercise.

고강도 저항성 운동이 24시간 평균동맥압과 심박수에 미치는 영향

박철호,우상헌 東亞大學校附設스포츠科學硏究所 2002 스포츠科學硏究論文集 Vol.20 No.-

As this study is to examine the effect of resistance exercise, it was made an experiment on resistance-trained group which conducted more than three times a week during 12 weeks and high-intensity resistance exercise of once during 60 minutes in the object of a young man in his 20s with normotensive and irregular exercise habit. After the exercise, MAP and heart rate(HR) during 24-h were changed as the following results. 1. On rest HR of resistance-trained group compared with non-trained group were significantly(p<.05) low, MAP of resistance-trained group compared with non-trained group were low but they were not significantly different. 2. The change of 24-h HR in resistance-trained group both resistance exercise day and control day didn't have the significant difference in all sections. 3. 24-h HR of non-trained group was significantly(p<.05) low between 9AM to 1PM on resistance exercise day compared with control day. 4. On control day, HR of resistance-trained group compared with non-trained group were significantly(p<.05) low between 9AM to 1PM. 5. On resistance exercise day, 24-h HR of resistance-trained group compared with non-trained group were significantly(p<.05) low, 24-h MAP is significantly(p<.05) high between 9AM to 1PM. In conclusion, rest heart rate(RHR) of resistance trained group were significantly(p<.05) low compared with mean, cardiovascular's function of resistance trained group compared with non-trained group were good. In all comparisons, 24-h heart rate(HR) and MAP were similar patterns, it showed they didn't have an influence on the change of 24-h blood pressure(BP) no matter how resistance exercise may be executed.

비만 유 · 무에 따른 저항성운동이 일시적, 장기적 Irisin 및 Myonectin 발현에 미치는 영향

최재일(Choi, Jae-Il),신정엽(Shin, Jeong-Yeop) 한국웰니스학회 2021 한국웰니스학회지 Vol.16 No.4

이 연구는 비만 유 · 무에 따른 저항성운동이 일시적, 장기적 irisin 및 myonectin 발현에 미치는 영향을 규명하기 위해 실시되었다. 20대 남성을 대상으로 실시되었으며 일반집단(NOG, n=20)의 경우 체지방률 20%이하인 남성 20명, 비만집단(OG, n=20)의 경우 체지방률 25%이상인 남성 20명을 선정하였다. 반복측정 분산분석을 실시한 결과 일시적 저항성운동(80%1RM, 8 reps, 2sets)에 따른 irisin 발현 수준에서는 NOG에서 안정시에 비해 운동종료 30분 후 유의하게 증가하였지만 OG에서는 유의한 차이가 나타나지 않았다. Myonectin 발현 수준에서는 모든 집단에서 안정시와 운동종료 30분 후 사이에 유의한 차이가 나타나지 않았고, 안정시와 운동종료 40분 시점에서 NOG가 OG에 비해 유의하게 높은 것으로 나타났다. 일시적 저항성운동 실험 종료 후 모든 대상자들을 일반운동집단(NORG, n=10), 일반통제집단(NOCG, n=10), 비만운동집단(ORG, n=10), 비만통제집단(OCG, n=10)으로 재분류하여 8주간 저항성운동을 실시하였다. 8주 후 일반집단의 종속변인의 차이를 비교하기 위해 반복측정 분산분석을 실시한 결과 다음과 같이 나타났다. 일반집단에서는 체지방률이 NORG가 NOCG보다 운동전에 비해 8주후 유의하게 감소한 것으로 나타났고, 근육량은 NORG가 NOCG보다 운동전에 비해 8주후 유의하게 증가한 것으로 나타났다. 또한 안정시 irisin과 myonectin은 NORG가 NOCG보다 운동전에 비해 8주후 유의하게 증가한 것으로 나타났다. 비만집단에서는 체중과 체지방률이 ORG가 OCG보다 운동전에 비해 8주후 유의하게 감소한 것으로 나타났고, 근육량은 ORG가 운동전에 비해 8주후 유의하게 증가한 것으로 나타났다. 또한 안정시 irisin과 myonectin은 ORG가 OCG보다 운동전에 비해 8주후 유의하게 증가한 것으로 나타났다. 이상의 결과를 종합해보면 운동경험이 없는 상태에서 일시적 저항성운동이 비만남성의 irisin 및 myonectin 발현 수준에는 영향을 미치지 못하는 것으로 나타났다. 그러나 장기적 저항성운동은 체지방률의 감소와 근육량의 증가로 인해 비만남성의 안정시 irisin 및 myonectin 발현 수준을 높이는 것으로 나타났는데 이는 근육량과 체지방률 수준이 irisin 및 myonectin 발현 수준에 영향을 미치는 것으로 사료된다. This study was conducted to investigate the effect of resistance exercise according to obesity on acute and long-term irisin and myonectin expression. This was conducted for men in their 20s. For the general group, 20 men with a body fat percentage of less than 20%(non-obese men group, NOG, n=20) and for the obese group, 20 men with a body fat percentage of 25% or more were determined(obese men group, OG, n=20). As a result of repeated measures ANOVA, the irisin expression level according to acute resistance exercise (80% 1RM, 8 reps, 2 sets) increased significantly in NOG 30 minutes after the end of exercise compared to at baseline, but there was no significant difference in OG. Myonectin expression level did not show a significant difference between resting time and 30 minutes after exercise in all groups, and NOG was found to be significantly higher than that of OG at baseline and 30 minutes after exercise. After the acute resistance exercise experiment, all subjects were reclassified into NORG (non-obese men resistance exercise group, n=10), NOCG (non-obese men control group, n=10), ORG (obese men resistance exercise group, n=10), and OCG (obese men control group, n=10) and resistance exercise was performed for 8 weeks. After 8 weeks, the results of repeated measurement ANOVA showed as follows. In the non-obese men groups, the percentage of body fat significantly decreased after 8 weeks in NORG than before exercise, and muscle mass increased significantly after 8 weeks in NORG compared to before exercise compared to NOCG. Also, irisin and myonectin at rest were significantly increased after 8 weeks in NORG than before exercise compared to NOCG. In the obese group, body weight and body fat percentage decreased significantly after 8 weeks compared to before exercise in ORG, and muscle mass increased significantly in ORG after 8 weeks compared to before exercise. Also, irisin and myonectin at rest were significantly increased after 8 weeks in ORG than before exercise compared to OCG. In summary, acute resistance exercise did not affect irisin and myonectin expression levels in obese men. However, long-term resistance exercise was shown to increase irisin and myonectin expression levels at rest in obese men due to a decrease in body fat percentage and an increase in muscle mass.

The Effect of Chronic Aerobic Exercise and Resistance Exercise on the Gene Expression of Ubiquitin Ligases

( Tae Young Kim ),( Hye Jin Kim ),( Won Jun Lee ) 한국체육학회 2016 국제스포츠과학 학술대회 Vol.2016 No.1

Purpose: It is well known that exercise plays an important role to maintain muscle mass through ubiquitin-proteasome system (UPS). However, the level of ubiquitin ligases which are involved in ubiquitin proteasome system in response to different exercise mode (aerobic exercise vs. resistance exercise) has not been clearly demonstrated. Therefore, the purpose of this study was to investigate the gene expression level of ubiquitin ligases (atrogin-1/MAFbx and MuRF1) in response to different types of exercise in skeletal muscle fiber of mice. Method: Female C57BL/6 mice were divided into aerobic exercise and resistance exercise group, and the experimental period was 10 weeks. The aerobic exercise group was made to swim in a pool 5 days per week. The exercise hour for this group was gradually increased from 20 minutes to 60 minutes, and the hour was fixed to 60 minutes from second week to the end of the experiment. The resistance exercise group was made to climb on a ladder 8 times a day and 3 days per week. For the first 2 weeks, the resistance exercise group was made to climb the ladder, being loaded with 10%, 50%, 75%, and 90% of their own weights. From week 3 to 8, the group have exercised being loaded with 100% of their own weights. For the last two weeks, the group of mice were made to exercise being loaded with 100% of their own weights. Result: Our data showed that chronic aerobic exercise significantly increased mRNA expression of atrogin-1/MAFbx in EDL, soleus, and gastrocnemius muscle. The level of MuRF1 mRNA was also increased in EDL, TA, soleus, and gastrocnemius muscle. Chronic resistance exercise increased mRNA level of atrogin-1/MAFbx and MuRF1 in EDL, TA, soleus, and gastrocnemius muscle. The mRNA expression of atrogin-1/MAFbx and MuRF1 tended to increase in plantaris muscle, but these increases were not significant. Conclusion: Although ubiquitin-proteasome system is well known for intracellular proteolytic system, the results of ubiquitin ligases expression level in response to different types of exercise are controversial. Several studies reported that either aerobic exercise or resistance training increased ubiquitin ligases gene expression. Our study also demonstrated that both exercise modes induced the mRNA expression of ubiquitin ligases (atrogin-1/MAFbx and MuRF1) in different types of skeletal muscle fiber, suggesting that ubiquitin ligases might play an important role not only in atrophying states but also in skeletal muscle turnover required for skeletal muscle growth in response to exercise. Further research is needed to see how these ubiquitin ligases affect skeletal muscle turnover.

유산소와 저항성 운동이 허약 여성노인의 근육감소증 지표, 염증성 사이토카인 및 인슐린저항성에 미치는 영향

강설중(SeolJungKang) 한국체육학회 2014 한국체육학회지 Vol.53 No.2

본 연구는 유산소와 저항성 운동이 허약 여성노인의 근육감소증 지표, 염증성 사이토카인 및 인슐린저항성에 어떠한 영향을 미치는지를 규명하기 위해 수행되었다. 연구대상자는 65세 이상 고령자 중 허약 노인여성으로 판정된 14명 여성으로서 운동군(7명)과 대조군(7명)으로 구분하였다. 운동군은 12주 동안 주 3회 유산소와 저항성 운동을 실시하였다. 유산소 운동은 여유심박수 40~59%에서 걷기 운동을 30분간 실시하였다. 저항성 운동은 탄성밴드를 이용하여 30분간 실시하였다. 운동 효과를 검증하기 위해 근육감소증 지표, 염증성 사이토카인 및 인슐린저항성을 사전, 사후 측정한 후 분석한 결과는 다음과 같다. 운동 프로그램 후 근육지수가 유의하게 증가하였다. 또한 염증성 사이토카인(TNF-a, IL-6, hs-CRP)은 유의한 차이가 나타나지 않았지만 인슐린저항성(혈당, 인슐린, HOMA-IR)은 유의하게 감소하였다. 결론적으로 유산소와 저항성 운동은 허약 여성노인의 근육지수 증가 및 인슐린저항성 감소에 효과적인 것으로 생각된다. This study was carried out in order to find out effects of the sarcopenia index, inflammation cytokine and insulin resistance in aerobic and resistance exercise of frail elderly women. The subjects consisted of the exercise group(n=7), and control exercise group(n=7). Exercise group had exercise 3 times a week for 12 weeks with the aerobic exercise and resistance exercise. The exercise group to be performed the aerobic exercise was intensity of heart rate reserve 40~59% for 30 minutes and the resistance exercise was performed for 30 minutes using elastic band. The sarcopenia index, inflammatory cytokine, and insulin resistance were measured and analyzed at pre- and post- exercise program. 1) The skeletal muscle index(SMI) were significantly increased after exercise program. 2) The Inflammatory cytokine(IL-6, TNF-α, and hs-CRP) levels did not significantly differ after exercise program. 3) The Insulin resistance(blood glucose, insulin, and HOMA-IR) were significantly decreased after exercise program. Conclusion, Aerobic and resistance exercise program had beneficial effects on SMI, and insulin resistance in frail elderly women.