21세기 새로운 시대를 준비하는 원광대학교 의과대학의 교육목표 개정과정

이학승,김요식,송윤강,오재민,양연식,정선관 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

교육목적은 대학의 교육이 지향하는 대전제이다. 그러므로 대학교육 목적과 목표가 어떤가에 따라 교육과정과 교육방법이 달라진다. 원광대학교 의과대학의 교육목표는, '지덕겸수'로 요약되는 '과학과 도학을 겸비한 전인교육'의 건학정신과 '학술탐구'와 '덕성함양'의 원광대학교 교육목표와 일치하게 현재까지 유지되었다. 그러나 현행 교육목표의 여러 문제점이 발견되었고, 시대상의 변화에 따라 원광대학교 의과대학에서도 사회적 변화 빛 의료인에 대한 시대적 요구에 걸맞은 의학교육의 목적 및 목표의 재설정 과정을 시작하게 되었다. 그 결과 개정 작업을 통해 새로운 교육목표를 설정하게 되었으며 그 내용은 다음과 같다. 1. 기본진료능력을 지닌 의사를 양성한다. 2. 원불교 교리 이념을 반영한 윤리적, 도덕적인 의사를 양성한다. 3. 평생 학습하는 연구하는 의사 혹은 의과학자를 양성한다. 4. 사회적 책무를 수행하는 리더십을 갖춘 의사를 양성한다. 5. 지역 사회에 공헌하는 봉사정신을 갖춘 의사를 양성한다. Purpose : With the changes to the medical environments and to the medical educational systems, we aimed to evaluate the current mission statement of the School of Medicine, Wonkwang University, and to revise it. Methods : To establish the new goal and mission statement, a Special Committee for the Revision of Medical School Mission and advisory group were organized in 2008. This special committee conducted through five steps of action, which are composed of investigation, education, development, surveillance of various opinions, and announcement. Results : For the development of new goal and mission, the revised, final goal and mission statements decided through the five steps of action. The new mission of Wonkwang University School of Medicine was as follows; 1. Doctor who can diagnose and treat easily 2. Ethical and moral doctor who practice Won Buddhism 3. Doctor or Medical Scholar who studies lifelong study 4. Doctor who has leadership to social responsibility 5. Doctor who goes into service to a local community. Conclusion : The authors expect that the new goal and mission of Wonkwang University School of Medicine would be helpful in giving the guideline on the educational process of medical school and will give the information to reform the medical school system according to the rapidly changing educational environment.

증례 ( Case Reports ) : 제 6 차 전북대학교 의과대학 학술집담회 초록 : Mepirizole 유도 십이지장궤양에 관한 실험적 연구

연구소자료 전북대학교 의과학연구소 1985 全北醫大論文集 Vol.9 No.4

행촌 (杏邨) 김상호 (金象皓) 교수 정년 기념호, 행촌 (杏邨) 김상호 (金象皓) 교수 약력 (略歷)

연구소자료 전북대학교 의과학연구소 1997 全北醫大論文集 Vol.21 No.1

N/A

덕암 (德巖) 황인담 (黃仁澹) 교수 화연기념호 (花宴紀念號), 덕암 황인담 교수 약력

연구소자료 전북대학교 의과학연구소 1986 全北醫大論文集 Vol.10 No.1

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우보 (牛步) 하대유 (河大有) 교수 화연기념호 (花宴紀念號), 하대유 교수 약력 (略歷)

연구소자료 전북대학교 의과학연구소 1993 全北醫大論文集 Vol.17 No.1

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고콜레스테롤 혈증 환자에서 Cerivastatin(LIPOBAY, 의과학연구소)의 임상효과 및 안전성에 관한 연구

박성훈,김미연,정수진,이영숙,박창한,변은경,전성희 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3

목적 : Cerivastatin(LIPOBAY)은 최근에 개발되어 사용되기 시작한 HMG-CoA 환원효소 억제제로서 저용량으로 탁월한 콜레스테롤 강하효과를 보이는 약물이다. 저자들은 Cerivatatin(LIPOBAY)의 혈중 콜레스테롤 강하효과를 평가하고 약물의 안전성을 평가하기 위하여 본 연구를 시행하였다. 방법 : 고콜레스테롤혈증 환자 37명(남자 13명, 여자 24명)을 대상으로 하였다. 대상환자는 2주간의 저콜레스테롤 식이 후에도 혈청 콜레스테롤이 240㎎/㎗이상이거나, 관상동맥질환이 있는 환자는 혈청콜레스테롤이 220㎎/㎗이상인 경우 cerivastatin 0.4㎎을 8주간 복용하도록 하였다. 임상적 관찰과 검사실 검사(간기능검사, 일반혈액검사, 혈청지질검사)는 투약개시 후 4주 및 8주 후에 시행하였다. 결과 : Cerivastatin 0.4㎎을 4주간 투여한 후 측정한 LDL 콜레스테롤, 총콜레스테롤, triglyceride, 및 HDL 콜레스테롤은 각각 38%, 28.8%, 11.6% 및 7.8% 감소하였다. 총콜레스테롤/HDL 콜레스테롤 비 및 LDL/HDL비는 각각 20.8% 및 31.1% 감소하였다. 투약 8주후에 측정한 검사소견은 4주후에 비해 유의한 변화를 보이지 않았다. 한명의 환자(2.7%)에서 간기능 검사상 AST, 및 ALT의 지속적인 상승으로 투약을 중지하였다. 결론 : Cerivastatin 0.4㎎/day는 혈청콜레스테롤을 효과적으로 감소시켰으며 심각한 부작용은 볼 수 없었다. 따라서 적극적으로 LDL콜레스테롤을 낮출 필요가 있는 고콜레스테롤혈증 환자에서 cerivastatin은 효과적이고 안전한 약물이라고 생각된다. Objectives : Cerivastain(LIPOBAY) is recently developed HMG-CoA reductase inhibitor which is effective in lowering serum cholesterol levels at microgram does. We evaluated the clinical efficacy and safety of cerivastatin(LIPOBAY) in patients with hypercholesterolemia. Method : Thirty-seven patients(male : 13, female : 24) with hypercholesteolemia defined as baseline serum total cholesterol ≥240㎎/㎗, or ≥220㎎/㎗ in patients with known coronary artery disease were included for this study. After 2 weeks of low cholesterol diet, if the serum total choesterol level meet the criteria, cerivastain 0.4㎎/day was prescribed for 8 weeks. Clinical follow-up and laboratory tests were performed 4 weeks and 8 weeks after medication. Results : After 4 weeks of cerivastain 0.4㎎/day treatment, low density lipoprotein(LDL) cholesterol decreased 38% and total cholesterol decreased 28.8% from baseline. Triglyceride decreased 11.6%, and high density lipoprotein(HDL) cholesterol decreased 7.8% from baseline. Total cholesterol/HDL ratio decreased 20.8% and LDL/HDL ratio decreased 31.1% from baseline. After 8 weeks of treatment, no further significant changes were noted compared with the values at 4 weeks. Cervastatin was discontinued in one patient(2.7%) due to continuous liver enzyme elevation. Conclusion : Cerivastatin 0.4㎎/day is effective in lowering serum cholesterol levels without significant adverse reactions. Cerivastatin is effective and safe for patients with hypercholesterolemia who needs aggressive LDL cholesterol lowering.

脾摘出 白鼠의 網內系 貪食能에 미치는 ACTH 및 Cortisone의 影響

이혜수,김형겸,최호열 의과학연구소 1991 全北醫大論文集 Vol.15 No.4

To investigate relationship between the mechanism of ACTH(RES acclerator) and Cortisone(RES suppressor) on the reticuloendothelial phagocytic function and the role of spleen, after the intramuscular injection of ACTH(1 USP & 2 USP/100gm of body weight) and Cortisone(1mg/100gm of body weight) into the splenectomized rats, the phagocytic activity of RES was assessed by means of carbon clearance method and their effects were compared with nosplenectomized group. The results were obtained as follows : 1. In the nosplenectomized group treated with ACTH, the phagocytic activity was increased markedly, but decreased significantly in the Cortisone treated group compared with control group. 2. In the splenectomized group, the enhancing effects of ACTH and suppressing effects of Cortisone on the RES function were not observed. 3. From these results, it is suggested that the influences of ACTH and Cortisone on the phagocytic function of RES was exhibited through the mediation of spleen.

Profilin에 의한 Phospholipase C-γ의 억제

조남천,한홍주 의과학연구소 1991 全北醫大論文集 Vol.15 No.4

Proslin isolated from Acanthamoeba inhibited the hydrolysis of phosphatidylinositol - 4,5-biphosphate (PIP2) by PLC-r, but not by PLC-B or PLC-A Compared to the low Ca2+ concentration high ooncentratien of Cn2+ (2mM) gave higher inhibitory effect of profilin on the PIP2 hydrolysis of PLC-y. These results suggest that profilin may participate in the regulation of phosphoinositide signal transduction system as well as its established function as an inhibitor of actin polymerization.

백서에서 Phenobarbital의 약물의존 발생기전에 관한 연구

정회상,김용기,은홍배,조규박 의과학연구소 1992 全北醫大論文集 Vol.16 No.1

It has been well known that chronic intoxication with barbiturate result in both physical dependence and withdrawal symptoms. To elucidate its mechanism withdrawal symptoms induced by naloxone, hot-plate latency and content of B-endorphin as well as [^3H]-morphine binding of midbrain rats. Oral phenobarbital (10mg/kg for 6 wks) did not elicit withdrawal symptoms, but 30mg/kg of the drug for 6 weeks induced abstinence signs such as jumping ptosis, penile licking teeth chattering and wet-dog shaking Phenobarbital also induced time- and dose-dependent increase of hot-plate lotency. Phenobarbital significantly increased B-endorphin content of the midbrain and decreased Bmax of [^3H]-morphine binding. However, Kd value was not changed. These results indicate that central opioidergic systems play an important role in development of physical dependence and withdrawal symptoms with chronic phenobarbital.

ENFLURANE 마취와 관련된 간염 1예 보고

오명성,남정자,황금만,이수택,김대곤,안득수 의과학연구소 1992 全北醫大論文集 Vol.16 No.1

We experienced a 36-year-old male patient showing unknown hepatitis fallowing enflurane anesthesia. Enflurane was commonly used in the patients with hepatic dysfunction due to its higher stability and lower hepatotoxicity by intermediate metabolities of enflurane rather than halothane. Enflurane-associated hepatitis has been reported uncommonly. In our case, hepatitis developed at 14th days after enflurane anesthesia. In the early phase, fever, eosinophilia and transaminases elevation were developed. In this point of view, clinical features of our case were similar to those of other reported cases. Patient's clinical symptoms and liver function such as levels of AST, ALT and total bilirubin were normalized within 4 weeks after enflurane anesthesia. But, 1 month later, the patient readmitted due to a severe jaundice. Jaundice was improved slowly for the next three months. The findings of liver biopsy showed a severe cholestatic hepatitis that were similar to viral hepatitis. So, we managed him with supportive treatment and he was slowly improved. We report this case with the review of relevant literature. (Key words : Enflurane, hepatitis)