배달 미니 게임 개발:"최고의 웨이터를 꿈꾸며"

김정훈,정한교,김영옥,김중곤,박정윤,윤진성,김경식 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 미니 게임은 웨이터라는 직업을 모티브로 하여서 남녀노소 누구나 재미를 느낌과 동시에 기억력 향상시켜 주는 게임제작이라는 목적아래 제작되었다.본 논문에서는 이 게임의 제작과정을 기술하고자 한다.이 게임은 제3회 AGC(한국 아마추어 게임제작 공모전)에서 우수 작으로 선정되었다.

정상인에서 베타3-아드레날린 수용체 유전자의 변이가 복부 비만도 및 지질대사에 미치는 영향

김영선,윤석기,김철희,서교일,김학선,김극배,변동원,유명희 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

The β₃-adrenergic receptor is expressed in visceral adipose tissue in humans and is thought to contribute to the regulation of the resting metabolic rate and lipolysis. We studied the influence of a mutation in the β₃ -adrenergic receptor gene(Trp64Arg) on body fat distribution, central obesity, lipid metabolism in 65 healthy young male adults. One out of 65 subjects were homozygous (Arg/Arg) for the trp64Arg mutation, 17 subjects were heterozygous (Trp/Arg), and 47 lacked the mutation(Trp/Trp). The body weight, height, body mass index, waist-to-hip ratio were similar between the subjects with- and without the mutation. Total body fat, abdominal fat amount, body fat distribution, serum total- and HDL-cholesterol, triglyceride, glucose, and insulin concentrations were also not different according to the presence or absence of the mutation. These results suggested that Trp64Arg mutation in β₃-adrenergic receptor gene is not a major contributing factor for central obesity or change in lipid metabolism in Korean young adults.

항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

Stage II B형 골육종에 대한 술전 항암화학요법 및 수술적 치료 결과

김정만,우영균,김형민,김훈교,이승구,강용구 가톨릭중앙의료원 가톨릭암센터 1997 암심포지움 Vol.- No.1

Recent advances in imaging techniques, surgery and combination anti-cancer chemotherapy have brought high survial rates in osteosarcoma. To investigate the survival rate, local recurrence and complications in treatment, we analysed 25 osteosarcoma cases who had been treated with preoperative neo-adjuvant chemotherapy, surgery and post operative chemotherapy at Department of Orthopedic Surgery, Catholic University. From May 1988 to April 1995, 42 cases of stage IIB osteosarcoma were admitted in Department of Orthopedic surgery. Among them, 17 cases who didn't follow our treatment guidance were excluded in this study. The average age were 19 years. There were 21 males and 4 females. The involved sites were 4 humerus, 10 femur, 10 tibia and 1 talus. Eleven cases had received intra-arterial cisplatin and intravenous adriamycin chemotherapy, and 7 T-10 protocol and 7 intravenous ifosfamide, ADR, methotrexate, cisplatin. Among twenty-three cases were treated with limb salvage surgery, and 2 amputation. The average follow-up was 35 months(3-82). There were 14 cases of continuous disease free, 9 cases of died of desease, 1 case of alive with disease, and 1 case of no evidence of disease at final follow-up. There were three cases of local recurrence at 6,8 and 12 months after operation. The Estimated kaplan-Meier's 5 year survival rates for all, ADR-cisloatin group, T-10 protocol group, and ifosfamide regimen group were 66%, 73%, 44% and 72%, respectively.

NITRIC OXIDE와 치수

김영경,김성교 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.5

Nitric oxide (NO) is a small molecule (mol. wt. 30 Da) and oxidative free radical. It is uncharged and can therefore diffuse freely within and between cells across membrane. Such characteristics make it a biologically important messenger in physiologic processes such as neurotransmisson and the control of vascular tone. NO is also highly toxic and is known to acts as a mediator of cytotoxicity during host defense. NO is synthesized by nitric oxide synthase (NOS) through L-arginine/nitric oxide pathway which is a dioxygenation process. NO synthesis involves several participants, three co-substrates. five electrons, five co-factors and two prosthetic groups. Under normal condition, low levels of NO are synthesized by type Ⅰ and Ⅱ NOS for a short period of time and mediates many physiologic processes. Under condition of oxidant stress, high levels of NO are synthesized by type Ⅱ NOS and inhibits a variety of metabolic processes and can also cause direct damage to DNA. Such interaction result in cytostasis, energy depletion and ultimately cell death. NO has the potential to interact with a variety of intercellular targets producing diverse array of metabolic effects. It is known that NO is involved in hemodynamic regulation, neurogenic inflammation. re-innervation, management of dentin hypersensitivity on teeth. Under basal condition of pulpal blood flow, NO provides constant vasodilator tone acting against sympathetic vasoconstriction. Substance P, a well known vasodilator, was reported to be mediated partly by NO, while calcitonin-gene related peptide had provided no evidence of its relation with NO. This review describes the roles of NO in dental pulp in addition to the known general roles of it.

점증적 최대운동부하가 테니스 선수들의 혈액 성분에 미치는 영향

김을교,최동재,조영호 명지대학교 예체능연구소 2001 藝體能論集 Vol.12 No.-

The purpose of this study was to investigate the effect of maximal exercise ability and LAC, NH3, LDH, Glucose on the progressive maximal exercise in high-school tennis players. The total sample was 14 students of high-school male, consisted of 7 students for athletes group, 7 students for non-athletes group The results were as follows : 1. HR was shown to significantly low in between athletes group and non-athletes group. 2. VO2max was shown to significantly high in between athletes group and non-athletes group. 3. Immediately after exercise LAC was't shown to significantly in between athletes group and non-athletes group. 4. Immediately after exercise NH3 was't shown to significantly in between athletes groups group and non-athletes group. 5. Immediately after exercise LDH was't shown to significantly in between athletes groups group and non-athletes group. 6. Immediately after exercise Glucose was't shown to significantly in between athletes groups group and non-athletes group. From the study, long-term tennis play was elevation cardiorespiratory functions and exercise ability in high-school tennis players, effective to improvement on tolerance functions

慶北地方의 作付體系 確立을 爲한 硏究 : 慶北地方內 地域間 作付體系 現況調査 및 分析 Survey and Analysis on the Present Cropping System among Various Regions

김양춘,徐榮敎,金達雄 慶北大學校 1978 論文集 Vol.25-26 No.-

The objective of this investigation was to obtain the necessary information for the increment of the cultivated land utilization and the establishment of more reasonable multiple cropping system in paddy and upland around Kyungpook Province. For the analysis of the obtained data we used the fixed model employing the arbitrary classification of the regions in sampling. The results of this investigation were summarized as follows: 1. In the acreage per farm household, it was obvious that the farm household in the suburban and truck farming regions has more upland acreage than paddy. On the contrary, there was the exactly reverse trend in the intermediate and fall-behind regions. 2. The old Japonica rice varieties were utilized in the suburban and truck farming regions comparing with the intermediate and fall-behind region using the new Indica-Japonica rice varieties. This tendency in the suburban and truck farming regions was closely associated with the cultivation, especially the harvesting date, of the post-crop after rice. Therefore, it was highly recommandable to develop new high yielding rice variety for the late transplanting in these regions. 3. The rate of the paddy utilization was the highest in the suburban region and was very low in the intermediate and fall-behind region. On the whole regions, the larger paddy owner utilized the lesser in its rate. 4. Barley was cultivated most widely as post-corp after rice in the sampling area. Vegetables in the suburban regions and water melon in Seongju and garlic in the Euiseong were main post-crops in the paddy multiple cropping systems. 5. The rate of the upland utilization was the highest in the suburban regions and was very low in the truck farming region because red pepper and tobacco production region employing only one crop per year. 6. In the double cropping system on the upland, barley and soybean combination was most in the cultivated acreage. The main double cropping system available in the suburban region was fruit vegetables and Chinese cabbage combination. 7. For the increment of the paddy and upland utilization, and of the farm income through the establishment of the reasonable cropping system, it will be desirable to study various possible multiple cropping systems on the experimental basis and the introduction of new crops and varieties may be considered for the incentive of production and return.

공공 건설공사 중 부도에 따른 공사지연 방지 방안 : Focused on Apartment Houses

김백용,조영준,구교진,현창택 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

The purpose of this study was to reduce the factor of construction delay in the owner's aspect by analyzing the actual condition of field supervision positively such as construction delay sample and process at the distressed company's construction site. As we analyze the examples of construction delay and reopening into various types, to minimize construction delay after the dishonor of a contractor we propose "Cooperation and reliance fixing between the contract parties through the improvement of order method, Contracting system and Construction management system".

갑상선 종양에서 thrombin receptor (PAR-1)의 발현 양상

박지영,목지오,김여주,박형규,김철희,변동원,서교일,유명희,조현득,오미혜,김상진 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2

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양배추 組織培養에서 體細胞 胚의 誘起

金暎來,朴敎善,朴順五,李永馥 충남대학교부설 생명공학연구소 1991 생물공학연구지 Vol.1 No.-

Leaf tissue segments of cabbage (Brassica oleracea. L.) were cultured on the MS medium supplemented with BA and 2, 4-D or NAA. 2, 4-D promoted callus induction but not shoot or root organogenesis. The highest callus induction frequency obtained at treatment of BA 0.2 and 2, 4-D 0.2 ㎎/l. High concentration of 2, 4-D 5.0㎎/l inhibited callus formation. BA promoted shoot formation at the 1.0㎎/ℓ and complementary treatment of BA and NAA was more effective on the formation of shoot and root. Multiple shoots were formed on the medium supplemented with BA 1.0 and NAA 0.5-1.0㎎/l, and BA 0.5 and NAA 2.0㎎/l. Higher concentration of NAA 5.0㎎/ℓ inhibited shoot formation. The highest root formation was induced at the NAA 1.0-2.0㎎/l. Embryogenesis was not induced on leaf disk culture.