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      • 객체 관계형 데이타베이스 관리 시스템을 이용한 디지털 앨범의 설계 및 구현

        이준서,장염승,한기준 건국대학교 산업기술연구원 2000 건국기술연구논문지 Vol.25 No.-

        As the storage capacity of a computer system is rapidly increasing and the cost of computer hardware is decreasing continuously, users can easily manage multimedia data on the personal computer. Especially, various image view programs are widely used to manage image files at the present time. However, since most of these programs do not use a database management system(DBMS), it is very difficult for users to use them efficiently. In this paper, we designed and implemented a Digital Album by using an object-relational database management system, called PARODY(Persistent, Almost, Relational Object Database sYstem) that implements a persistent object database with a relatively simple interface to its C++ class library. Since PARODY is used as a data storage manager of the Digital Album, users can manage(i.e., insert, update, and delete) an image database and search for the required image data from the image database easily. In addition, we use OWL(Object Windows Library) of Borland C++ to implement the user interface of the Digital Album efficiently.

      • Health-related Quality of Life After Treatment for Malignant Bone Tumors: A Follow-up Study in China

        Sun, Yong-Jian,Hu, Yan-Jun,Jin, Dan,Li, Jian-Wei,Yu, Bin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

        Aim: We conducted the present study to assess health-related quality of life (HRQoL) among bone cancer patients after surgical treatment in one large teaching hospitals in China, and assess the risk factors for improving the physical or mental HRQoL. Methods: 344 eligible adult patients who were admitted to the hospital with malignant bone tumors during the period of Jun. 2008 to Dec. 2011, and a reference group with 361 health cases was recruited in the same hospital during the same period. All 344 patients were followed up for one year. The HRQoL before treatment and after one year was evaluated with the Medical Outcome Short Form 36 (SF-36). Results: All 8 domains of HRQoL had the lowest scores greatly improved over the first year after discharge. However, the patients still had significantly lower scores in every domain than the reference group one year after discharge. Age and type of surgery were associated with HRQoL in the mental domain. Conclusion: The HRQoL of patients with malignant bone tumors greatly improved one year after the treatment. This study also highlighted the utility of HRQoL assessment for prognostic evaluation of patients after surgical treatment for bone cancer.

      • SCIESCOPUSKCI등재

        Production and Characterization of Ethanol- and Protease-Tolerant and Xylooligosaccharides-Producing Endoxylanase from Humicola sp Ly01

        ( Jun Pei Zhou ),( Qian Wu ),( Rui Zhang ),( Yu Ying Yang ),( Xiang Hua Tang ),( Jun Jun Li ),( Jun Mei Ding ),( Yan Yan Dong ),( Zun Xi Huang ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.6

        This paper reports the production and characterization of crude xylanase from the newly isolated Humicola sp. Ly01. The highest (41.8 U/ml) production of the crude xylanase was obtained under the optimized conditions (w/v): 0.5% wheat bran, 0.2% KH2PO4, and 0.5% peptone; initial pH 7.0; incubation time 72 h; 30℃; and 150 rpm. A considerable amount of the crude xylanase was induced using hulless barley bran or soybean meal as the carbon source, but a small amount of the enzyme was produced when supplementary urea was used as the nitrogen source to wheat bran. The crude xylanase showed apparent optimal cellulase-free xylanase activity at 60℃ and pH 6.0, more than 71.8% of the maximum xylanase activity in 3.0-30.0% (v/v) ethanol and more than 82.3% of the initial xylanase activity after incubation in 3.0-30.0% (v/v) ethanol at 30℃ for 2 h. The crude xylanase was moderately resistant to both acid and neutral protease digestion, and released 7.9 and 10.9 μmol/ml reducing sugar from xylan in the simulated gastric and intestinal fluids, respectively. The xylooligosaccharides were the main products of the hydrolysis of xylan by the crude xylanase. These properties suggested the potential of the crude enzyme for being applied in the animal feed industry, xylooligosaccharides production, and high-alcohol conditions such as ethanol production and brewing.

      • KCI등재

        Molecular and Biochemical Characterization of a Novel Intracellular Low-Temperature-Active Xylanase

        ( Jun Pei Zhou,),( Yan Yan Dong ),( Xiang Hua Tang ),( Jun Jun Li ),( Bo Xu ),( Qian Wu ),( Ya Jie Gao ),( Lu Pan ),( Zun Xi Huang ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.4

        A 990 bp full-length gene (xynAHJ2) encoding a 329- residue polypeptide (XynAHJ2) with a calculated mass of 38.4 kDa was cloned from Bacillus sp. HJ2 harbored in a saline soil. XynAHJ2 showed no signal peptide, distinct amino acid stretches of glycoside hydrolase (GH) family 10 intracellular endoxylanases, and the highest amino acid sequence identity of 65.3% with the identified GH 10 intracellular mesophilic endoxylanase iM-KRICT PX1-Ps from Paenibacillus sp. HPL-001 (ACJ06666). The recombinant enzyme (rXynAHJ2) was expressed in Escherichia coli and displayed the typical characteristics of low-temperatureactive enzyme (exhibiting optimum activity at 35 o C, 62% at 20 o C, and 38% at 10 o C; thermolability at ≥45 o C). Compared with the reported GH 10 low-temperature-active endoxylanases, which are all extracellular, rXynAHJ2 showed low amino acid sequence identities (<45%), low homology (different phylogenetic cluster), and difference of structure (decreased amount of total accessible surface area and exposed nonpolar accessible surface area). Compared with the reported GH 10 intracellular endoxylanases, which are all mesophilic and thermophilic, rXynAHJ2 has decreased numbers of arginine residues and salt bridges, and showed resistance to Ni 2+ , Ca 2+ , or EDTA at 10 mM final concentration. The above mechanism of structural adaptation for low-temperature activity of intracellular endoxylanase rXynAHJ2 is different from that of GH 10 extracellular low-temperature-active endoxylanases. This is the first report of the molecular and biochemical characterizations of a novel intracellular low-temperatureactive xylanase.

      • KCI등재

        Cloning, Heterologous Expression, and Characterization of Novel Protease- Resistant α-Galactosidase from New Sphingomonas Strain

        ( Jun Pei Zhou ),( Yan Yan Dong ),( Jun Jun Li ),( Rui Zhang ),( Xianghua Tang ),( Yuelin Mu ),( Bo Xu ),( Qian Wu ),( Zun Xi Huang ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.11

        The α-galactosidase-coding gene agaAJB13 was cloned from Sphingomonas sp. JB13 showing 16S rDNA (1,343 bp) identities of ≤97.2% with other identified Sphingomonas strains. agaAJB13 (2,217 bp; 64.9% GC content) encodes a 738-residue polypeptide (AgaAJB13) with a calculated mass of 82.3 kDa. AgaAJB13 showed the highest identity of 61.4% with the putative glycosyl hydrolase family 36 α-galactosidase from Granulicella mallensis MP5ACTX8 (EFI56085). AgaAJB13 also showed <37% identities with reported protease-resistant or Sphingomonas α-galactosidases. A sequence analysis revealed different catalytic motifs between reported Sphingomonas α-galactosidases (KXD and RXXXD) and AgaAJB13 (KWD and SDXXDXXXR). Recombinant AgaAJB13 (rAgaAJB13) was expressed in Escherichia coli BL21 (DE3). The purified rAgaAJB13 was characterized using p-nitrophenyl-α-D-galactopyranoside as the substrate and showed an apparent optimum at pH 5.0 and 60oC and strong resistance to trypsin and proteinase K digestion. Compared with reported proteaseresistant α-galactosidases showing thermolability at 50oC or 60oC and specific activities of <71 U/mg with or without protease treatments, rAgaAJB13 exhibited a better thermal stability (half-life of >60 min at 60oC) and higher specific activities (225.0-256.5 U/mg). These sequence and enzymatic properties suggest AgaAJB13 is the first identified and characterized Sphingomonas α-galactosidase, and shows novel protease resistance with a potential value for basic research and industrial applications.

      • KCI등재

        Base Station Placement for Wireless Sensor Network Positioning System via Lexicographical Stratified Programming

        ( Jun Yan ),( Kegen Yu ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.11

        This paper investigates optimization-based base station (BS) placement. An optimization model is defined and the BS placement problem is transformed to a lexicographical stratified programming (LSP) model for a given trajectory, according to different accuracy requirements. The feasible region for BS deployment is obtained from the positioning system requirement, which is also solved with signal coverage problem in BS placement. The LSP mathematical model is formulated with the average geometric dilution of precision (GDOP) as the criterion. To achieve an optimization solution, a tolerant factor based complete stratified series approach and grid searching method are utilized to obtain the possible optimal BS placement. Because of the LSP model utilization, the proposed algorithm has wider application scenarios with different accuracy requirements over different trajectory segments. Simulation results demonstrate that the proposed algorithm has better BS placement result than existing approaches for a given trajectory.

      • SCIESCOPUSKCI등재

        Cucumber Growth and Nitrogen Uptake as Affected by Solution Temperature and NO<sub>3</sub><sup>-</sup>:NH<sub>4</sub><sup>+</sup> Ratios during the Seedling

        Yan, Qiu-Yan,Duan, Zeng-Qiang,Li, Jun-Hui,Li, Xun,Dong, Jin-Long Korean Society of Horticultural Science 2013 원예과학기술지 Vol.31 No.4

        The effect of solution temperature and nitrogen form on cucumber (Cucumis sativus L.) growth, photosynthesis and nitrogen metabolism was investigated in hydroponic culture. Cucumber plants were grown for 35 days in a greenhouse at three constant solution temperatures ($15^{\circ}C$, $20^{\circ}C$, and $25^{\circ}C$) within a natural aerial temperature ($15-30^{\circ}C$). Four nitrate:ammonium ($NO{_3}^-:NH{_4}^+$) ratios (10:0, 8:2, 5:5, and 2:8 $mmol{\cdot}L^{-1}$) at constant nitrogen (N) concentration of $10mmol{\cdot}L^{-1}$ were applied within each solution temperature treatment. Results showed an increasing solution temperature enhanced plant growth (height, dry weight, and leaf area) in most N treatments. Dry weight accumulation was greatest at the 10:0 $NO{_3}^-:NH{_4}^+$ ratio in the $15^{\circ}C$ solution, the 5:5 ratio in the $20^{\circ}C$ solution and the 8:2 ratio in the $25^{\circ}C$ solution. Photosynthetic rate (Pn) response to solution temperature and $NO{_3}^-:NH{_4}^+$ ratio was similar to that of plant growth. Probably, the photosynthate shortage played a role in the reduced biomass formation. Increasing solution temperature enhanced the nitrate reductase (NR) activity, and further reduced shoots nitrate content. Our results indicate that the optimal ratio of nitrate to ammonium that promotes growth in hydroponic cucumber varies with solution temperature.

      • SCOPUS

        Computing and Reducing Transient Error Propagation in Registers

        Jun Yan,Wei Zhang 한국정보과학회 2011 Journal of Computing Science and Engineering Vol.5 No.2

        Recent research indicates that transient errors will increasingly become a critical concern in microprocessor design. As embedded processors are widely used in reliability-critical or noisy environments, it is necessary to develop cost-effective fault-tolerant techniques to protect processors against transient errors. The register file is one of the critical components that can significantly affect microprocessor system reliability, since registers are typically accessed very frequently, and transient errors in registers can be easily propagated to functional units or the memory system, leading to silent data error (SDC) or system crash. This paper focuses on investigating the impact of register file soft errors on system reliability and developing cost-effective techniques to improve the register file immunity to soft errors. This paper proposes the register vulnerability factor (RVF) concept to characterize the probability that register transient errors can escape the register file and thus potentially affect system reliability. We propose an approach to compute the RVF based on register access patterns. In this paper, we also propose two compiler-directed techniques and a hybrid approach to improve register file reliability cost-effectively by lowering the RVF value. Our experiments indicate that on average, RVF can be reduced to 9.1% and 9.5% by the hyperblock-based instruction re-scheduling and the reliability-oriented register assignment respectively, which can potentially lower the reliability cost significantly, without sacrificing the register value integrity.

      • SCOPUS

        An Interference Matrix Based Approach to Bounding Worst-Case Inter-Thread Cache Interferences and WCET for Multi-Core Processors

        Jun Yan,Wei Zhang 한국정보과학회 2011 Journal of Computing Science and Engineering Vol.5 No.2

        Different cores typically share the last-level cache in a multi-core processor. Threads running on different cores may interfere with each other. Therefore, the multi-core worst-case execution time (WCET) analyzer must be able to safely and accurately estimate the worst-case inter-thread cache interference. This is not supported by current WCET analysis techniques that manly focus on single thread analysis. This paper presents a novel approach to analyze the worst-case cache interference and bounding the WCET for threads running on multi-core processors with shared L2 instruction caches. We propose to use an interference matrix to model inter-thread interference, on which basis we can calculate the worst-case inter-thread cache interference. Our experiments indicate that the proposed approach can give a worst-case bound less than 1%, as in benchmark fib-call, and an average 16.4% overestimate for threads running on a dual-core processor with shared-L2 cache. Our approach dramatically improves the accuracy of WCET overestimatation by on average 20.0% compared to work.

      • KCI등재

        Behaviours of steel-fibre-reinforced ULCC slabs subject to concentrated loading

        Jun-Yan Wang,Xiao-long Gao,Jia-Bao Yan 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.71 No.4

        Novel steel fibre reinforced ultra-lightweight cement composite (ULCC) with compressive strength of 87.3MPa and density of 1649kg/m3 was developed for the flat slabs in civil buildings. This paper investigated structural behaviours of ULCC flat slabs according to a 4-specimen test program under concentrated loading and some reported test results. The investigated governing parameters on the structural behaviours of the ULCC slabs include volume fraction of the steel fibre and the patch loading area. The test results revealed that ULCC flat slabs with and without flexure reinforcement failed in different failure mode, and an increase in volume fraction of the steel fibre and loading area led to an increase in flexural resistance for the ULCC slabs without flexural reinforcement. Based on the experiment results, the analytical models were developed and also validated. The validations showed that the analytical models developed in this paper could predict the ultimate strength of the ULCC flat slabs with and without flexure reinforcement reasonably well.

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