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최택영,신용국 한국학교수학회 2002 韓國學校數學會論文集 Vol.5 No.1
The purpose of this study is to find out if there are meaningful differences between small rural middle schools and nearby urban ones in the mathematical diagnostic evaluation. It also says how to improve students' scholastic abilities, making up a question of attitudes towards math to know the mathematical abilities lowering cause in small rural middle schools. Findings are, 1. Students must recognize that studying math is essential and be interested in it. 2. The mathematical confidence is needed. 3. A strong will of studying math hard is important. 4. Students must have a motivational triggering, while solving math problems and then checking answers for themselves. 5. Backward countries' humanistic and social environmental factors should be overcome. In conclusion, we expect the mathematical abilities improvement, making students remove the mathematical abilities lowering cause after having a learning experience suitable for the rural community instead of negative attitudes towards math.
Chrysin attenuates atopic dermatitis by suppressing inflammation of keratinocytes
Choi, Jin Kyeong,Jang, Yong Hyun,Lee, Soyoung,Lee, Sang-Rae,Choi, Young-Ae,Jin, Meiling,Choi, Jung Ho,Park, Jee Hun,Park, Pil-Hoon,Choi, Hyukjae,Kwon, Taeg Kyu,Khang, Dongwoo,Kim, Sang-Hyun Elsevier 2017 Food and chemical toxicology Vol.110 No.-
<P><B>Abstract</B></P> <P>We previously reported the inhibitory effect of chrysin, a natural flavonoid plentifully contained in propolis, vegetables and fruits, on the mast cell-mediated allergic reaction. In this study, we evaluated the effect of chrysin on atopic dermatitis (AD) and defined underlying mechanisms of action. We used an AD model in BALB/c mice by the repeated local exposure of 2,4-dinitrochlorobenzene (DNCB) and house dust mite (<I>Dermatophagoides farinae</I> extract, DFE) to the ears. Repeated alternative treatment of DNCB/DFE caused AD-like skin lesions. Oral administration of chrysin diminished AD symptoms such as ear thickness and histopathological analysis, in addition to serum IgE and IgG2a levels. Chrysin decreased infiltration of mast cells, and reduced serum histamine level. Chrysin also suppressed AD by inhibiting the inflammatory responses of Th1, Th2, and Th17 cells in mouse lymph node and ear. Interestingly, chrysin significantly inhibited the production of cytokines, Th2 chemokines, CCL17 and CCL22 by the down-regulation of p38 MAPK, NF-κB, and STAT1 in tumor necrosis factor (TNF)-α/interferon (IFN)-γ-stimulated human keratinocytes (HaCaT). Chrysin also inhibited TNF-α/IFN-γ-stimulated IL-33 expression in HaCaT cells and mouse primary keratinocytes. Taken together, the results indicate that chrysin suppressed AD symptoms, suggesting that chrysin might be a candidate for the treatment of AD and skin allergic diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Chrysin suppresses AD symptoms by inhibiting T helper cell immune reaction. </LI> <LI> Chrysin downregulates CCL17 and CCL22 expression via p38 MAPK, STAT1, and NF-κB in human keratinocytes. </LI> <LI> Chrysin and tacrolimus have overlapping effects in inhibiting AD immune responses. </LI> <LI> Chrysin might be a candidate for the treatment of skin allergic diseases. </LI> </UL> </P>
CFRP 판의 보강량 및 접착제의 종류에 따른 GFRP 각형 부재의 휨보강 성능에 관한 실험적 연구
이용택 ( Lee¸ Yong-taeg ),김승훈 ( Kim¸ Seung-hun ),박해용 ( Park¸ Hae-yong ),박세희 ( Park¸ Se-hee ),최진철 ( Choi¸ Jin-chul ) 한국구조물진단유지관리공학회 2023 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.27 No.2
이종복합재를 이용한 커튼월 프레임의 내부보강재 개발을 위하여, 본 연구에서는 탄소섬유강화플라스틱(CFRP) 판으로 보강된 유리섬유강화플라스틱(GFRP) 각형부재의 휨성능을 평가하기 위하여 휨 실험을 수행하였다. 휨 실험 결과 보강전 GFRP 각형부재에 비하여 CFRP 판으로 보강된 GFRP 각형부재가 강성이 크게 증가하는 것으로 나타났다. 특히, 보강폭에 따른 보강량의 증가에 따라 강성증가가 크게 나타났으며, 접착제의 종류에 따른 영향은 미비하였다.