진행성 치매와 반복되는 뇌졸중을 보인 뇌 아밀로이드 혈관병증 1예

유봉구,곽강호,김태유,김광수,유경무 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.1

Cerebral amyloid angiopathy can cause intracerebral hemorrhage, progressive dementia, seizure and transient ischemic attacks. Dementia is a relatively common manifestation and associated with the presence of recurrent strokes and leukoencephalopathy. A 66-year-old right-handed man with hypertension and recurrent strokes presented with rapidly progressive dementia and sudden onset of dysarthria and dizziness. He showed memory impairment, personality and behavioral changes, and executive dysfunction for one and an half years. These symptoms developed insidiously and quite rapidly without fluctuation. Brain CT showed a small hemorrhage in the right cerebellum. Brain MRI, especially gradient-echo images revealed multiple cortical and cortico-subcortical microbleeds. Four weeks later, right hemiparesis suddenly developed and a repeated MRI showed a new left corona radiata infarction. We learn from this case that gradient-echo MR images should be performed in patients with rapidly progressive dementia and recurrent strokes.

Papaverine이 단일 심근세포의 막전류에 미치는 영향

유경현,심태섭,방효원 중앙대학교 의과대학 의과학연구소 1991 中央醫大誌 Vol.16 No.4

Ventricular myocytes of guinea-pig were isolated by means of collagenase digestion in order to investigate the effects of papaverine on the membrane currents in them. After formation of a gigaseal with patch microelectrodes, membrane currents were recorded from single ventricular myocytes in a whole cell mode of patch-clamp technique. For membrane currents recording, electrodes were filled with Cs-solution. Results were as follows: 1. Slow inward calcium was reduced by papaverine dose-dependently. 2. No significant changes were observed in the steady-state inactivation. 3. Recovery time of the calcium currents prolonged in high concencial papaverine. 4. Fast inward sodium currents showed no noticeable changes with papaverine treatment. From these results, it is strongly suggested that the effects of papaverine on the membrane currents in the single ventricular myocytes may be attributable to its antagonistic action on the calcium channel rather than its inhibitory effect on the phosphodiesterase activity.

중학교 가정과 '인간발달과 가족관계' 영역의 교육자료 (CD-Rom) 개발 및 현장 적용 연구 : 실천적 추론 수업을 중심으로

유태명,장혜경,유지연,김주연,김항아,김효순 한국 가정과 교육 학회 2000 한국가정과교육학회지 Vol.12 No.3

The purpose of this study is to develop lesson plans. teaching guide, and teaching materials applying practical reasoning teaching model in the area of 'human development and family relationship' in middle school home economics. The practical reasoning teaching model consists of five factors: Desired results, Awareness of context. Alternative approaches, Consequences of action, and Action. This study based on practical reasoning has following process: Curriculum development, Developing lesson plan. teaching material, and teaching guide. Experimental teaching and evaluation, Feedback, Production of CD-Rom. Teaching guide includes lesson Plan. workbook, multimedia materials and teaching resources, Especially teaching guide in CD-Rom can be used effectively in the actual teaching. In the classroom, this teaching model accomplished active and interesting Participation of teachers and students. It is proposed that practical reasoning teaching model should be applied to other areas of home economics. In addition, various teaching materials based on Practical reasoning need to be developed.

자활후견기관사업 참여자가구의 제반 특성 및 경제적 어려움 정도에 영향을 미치는 요인에 관한 실증적 연구

유태균,김경휘 한국사회보장학회 2003 사회보장연구 Vol.19 No.1

시행 2년 6개월째로 접어들고 있는 자활지원사업에 대한 체계적이고 실증적인 연구의 부족은 자활사업 참여자(가구)의 특성을 이해하는데 필요한 자료의 부재라는 결과를 초래했다. 본 연구에서는, 이러한 자료 및 연구의 부재에 대한 인식을 바탕으로, 자활사업 참여자(가구)의 특성을 파악함과 동시에 이들의 경제적 어려움 정도에 영향을 미치는 요인을 실증적으로 규명 해보고자 시도하였다. 2002-2003년 말까지 2년간의 기간동안 계획된 4차례의 패널조사를 가운데 2002년 상반기에 완료된 1차년도 1차조사 자료를 분석한 결과, 첫째, 자활사업 참여자가구의 특성 가운데 경제활동을 하는 가구원의 유무, 사적이전소득 유무, 그리고 지역사회로부터의 지지정도가 자활사업에 참여하고 있는 참여자(가구)의 경제적 어려움의 정도에 결정적인 영향을 미치는 요인임을 발견할 수 있었고, 둘째, 자활지원사업에 참여하면서 가구의 총소득이 최저생계 유지를 위해 필요한 생계비에 미치는 못하는 '경제적 고위험집단(Financial High-Risk Group)'을 효과적으로 지원하기 위한 전략으로 자활사업 참여자에 대한 교육, 가족기능 증진을 위한 지원, 그리고 요보호 가구원을 가진 가구를 위한 지원이 시급하다는 사실을 알 수 있었다. Understanding the characteristics of the households participating the Self-Support programs(55P) launched in 2000 is of imperative in that little has been known up to date due to the lack of empirical study on 55P In realizing this lack of knowledge, these researchers have collected panel data on the households in SSP by conducting a total of four survey researches for the period of 2002-2003. Using the data collected from the 1st wave survey completed in May, 2002, these authors empirically examine the characteristics of this group as well as those factors affecting their financial suffering, Data analyses show 1) that whether or not having at least one working family member, the availability of the source of private income transfer, and the level of support from the community are the major determinants of the level of the household's financial suffering in 5SP, 2) that effective supporting strategies for those households that can be categorized into 'Financial High-Risk Croup', whose total household income falls short of the amount of expenditure for basic living even in SSP should include educating the 5SP participants, strengthening the level of family functioning, and providing the SSP participants with child-care services and social services for the elderly and people with chronic mental and physical problems, and 3) that for the government it is necessary to suspect in a serious manner the reasonableness of setting the goal of SSP as transforming SSPs into the Self-Sufficient Community. Some policy suggestions are made for the development of the Self-Support programs in the future.

강화 특화작목 지표물질의 함량 분석

유종수,방면호,정해곤,정태숙,최명숙,이경태,김세영,백남인 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

강화 특화작목의 건강기능성 식품 제품화의 가능성을 타진하고 재배작물의 표준화 연구를 위해 사자발쑥, 싸주아리쑥 그리고 순무에 대해 총 폴리페놀과 총 플라보노이드 함량을 측정하였다. 총 폴리페놀 함량은 사자발쑥이 9.5mg/g, 싸주아리쑥이 7.4mg/g, 순무가 1.8mg/g으로 총 플라보노이드 함량은 사자발쑥이 4.3mg/g, 싸주아리쑥이 3.6mg/g, 순무가 0.4mg/g으로 확인 되었다. 또한 강화 약쑥의 유효지표성분인 eupatilin과 jaceosidin이 사자발쑥에는 각각 208mg/100g, 118mg/100g, 싸주아리쑥에는 199mg/100g, 111mg/100g 함유된 것을 HPLC를 통해 확인하였다. This study was conducted to investigate the contents of total polyphenol and total flavonoid of three Ganghwa indigenous crops, two varieties of Artemisia princeps Pampanini (Sajabalssuk, Sajuarissuk) and Brassica campestris ssp rapa. Total polyphenol and total flavonoid contents of Sajabalssuk were 9.5 and 4.3 mg/g, those of Sajuarissuk were 7.4 and 3.6 mg/g, those of B. campestris ssp rapa were 1.8 and 0.4 mg/g, respectively. The contents of eupatilin and jaceosidin in A. princeps Pampanini which were calculated by HPLC, were determined 208 mg/100g, 118 mg/100g in Sajabalssuk and 199 mg/100g, 111 mg/100g in Sajuarissuk, respectively.

싸주아리쑥(Artemisia herba)으로부터 phytol의 분리

유종수,방면호,정해곤,정태숙,최명숙,이경태,백남인 경희대학교식량자원개발연구소 2006 硏究論文集 Vol.25 No.-

싸주아리쑥 지상부의 80% MeOH 추출물로부터 얻어진 EtOAc 분획물에 대하여 silica gel 및 ODS column chromatography를 반복하여 diterpene을 분리하였다. 화합물의 화학구조는, NMR, MS 및 IR 등의 스펙트럼을 해석하여 phytol로 동정하였다. The aerial part of Artemisia herba was extracted with 80% aqueous MeOH and the concentrated extract was partitioned with EtOAc, n-BuOH and H_(2)O, successively. From the EtOAc fraction, a terpenoid was isolated through the repeated silica gel and ODS column chromatographies. From the result of physico-chemical data including NMR, MS and IR, the chemical structure of the compound was determined as phytol.

부직포활성슬러지법에 의한 하수와 침출수처리에 관한 기초연구

정유진,고현웅,김경순,윤태경,성낙창 한국환경과학회 2003 한국환경과학회지 Vol.12 No.10

In this study, it was performed using submerged nonwoven bioreactor(SNBR) for removal of organic matter, nitrogen and phosphate under different aeration intervals(intermittent aeration). We applied the SNBR at the cheap nonwoven fiber module instead of the expensive membrane. The SNBR was mainly made up of an activated sludge reactor and a transverse flow nonwoven module. with an innovative configuration being in application between them. In case of sewage, the aeration conditions experimented consist of continuous aeration and 60min/60min, 120min/60min, 120min/120min of aeration/nonaeration time intervals, respectively. In case of landfill leachate, the intermittent aeration condition was 120min/120min at aeration/nonaeration. Consequently. a high COD removal rate (about 94%) was achieved in sewage and leachate. Although nutrient removal rate was relatively high without any additional chemicals.

위에 발생한 거대 위장관 간질종양 1예

이경영,유영범,김태원,이경룡 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Gastrointestinal tumors(GIST) are rare group of neoplasias of the gastrointestinal track, which originate from or differentiate into interstitial cells of Cajal (ICC). GIST traditionally have been designated as smooth muscle tumor. However, with increasingly accurate analytic tools, immunohistochemistry and ultrastructure, most investigators were able to demonstrate that ICC, a complex cellular network postulated to act as pacemaker cells of the gastrointestinal track, which exhibit both myoid and neural features, could be a candidate for tumor histogenesis. Most ICC are only c-kit-positive, however a subset are positive for both c-kit and CD34. Most GISTs are asymptomatic and are thus usually discovered incidentally during routine check, at operation of other organs. When symptoms occur, GISTs usually present with gastrointestinal bleeding due to ulceration of the overlying gastric mucosa. Bleeding may be massive, leading to hematemesis and melena. Recently, we experienced a large sized(5×5×5 cm) GIST on the upper body of the stomach, which caused massive upper gastrointestinal bleeding in a 61-year-old man and was treated by local resection with adequate safety margin about 2 cm.

스트레칭운동에서 온열요법이 요부의 유연성에 미치는 영향

황윤태,유경태,이미영,박래준 대구대학교 특수교육재활과학연구소 2007 再活科學硏究 Vol.25 No.1

스트레칭(stretching)은 최근 신체 각 부위를 적절하게 움직이게 하여 긴장과 피로를 풀어주어 신체 발달을 꾀하고 유연성을 향상시키는데 좋은 운동방법으로 평가되고 있다. 온열요법(heating therapy)은 신체부분에 국소적으로 열을 가하여 혈액의 순환을 증가시켜서 손상의 빠른 회복을 기대하여 물리치료학에서 현재 많이 이용되는 방법으로 관절 경직의 완화, 동통 완화, 그리고 근 경련의 감소에 효과적이다. 본 연구에서는 20대에서 40대 사이의 신경학적 제한이 없는 정상인을 대상으로, 스트레칭 운동을 시행할 때 혼합되는 온열요법이 요부의 유연성 개선에 미치는 효과를 알아보고자 하였다. 20대에서 40대 20명(남10, 여10명)을 10명씩 두 집단으로 나누어 한 집단은 8 동작의 스트레칭 시행하는 스트레칭 집단으로 하고, 다른 한 집단은 온습포(hot pack)와 8 동작의 스트레칭을 혼합하는 열-스트레칭 혼합 집단으로 하였다. 각 집단은 주 4회 6주간 실시되었으며, 유연성 검사를 위해 체간 굴곡(trunk flexion), 체간 신전(trunk extension), 그리고 요부의 유연성을 나타내는 Schober-test를 측정하였다. 두 그룹간의 차이를 연구하여 요부의 유연성 개선에 미치는 효과를 검증하였으며, 나아가 본 연구는 요부 안정화 프로그램의 중요성과 산업체 근로자와 장시간 같은 자세로 작업을 하는 장애자들에게서 흔히 발생하는 요부의 통증에 접근하기 위해 고안되었다. The purpose of this study is to verify the difference of effect between group and period in order to find out effect on lumbar flexibility of treatment modality(stretching, heat - stretching) and period. The subject was chosen from the mild physically normal person who range from 20 to 40 years old without any neurological problem. Among these subjects, 20 persons(10 male, 10 female) were selected to two different groups. These were classified as stretching and heat- stretching groups. In stretching group, 8 different kind of stretching exercises were performed. In heat-stretching group, hot pack and stretching were performed together with 8 different stretching exercises. For the measurement of flexibility, trunk flexion test, trunk extension test and Schober-test were used. Pre-test was performed before treatment test, post-test was performed after 6 week of treatment test. As a result of this test, the following fact was shown 1) In trunk flexion and trunk extension test, effect between groups did not occur but effect of treatment period showed significance statistically. In addition, interactive effect between treatment period and each group showed the biggest difference in heat and stretching group. 2) In Schober-test, effect of treatment period showed significance statistically, effect between group and interactive effect did not occur.

모래의 입도분포가 모르터의 물성에 미치는 영향에 관한 연구

김경원,김문희,김유진,안흥난,허태경,현철 경성대학교 공학기술연구소 2010 공학기술연구지 Vol.16 No.-

Fineness Modulus is a term used as an index to the fineness of sand. It is well - known that the modulus distribution of sand plays an important role in achieving the desired properties of mortar. The maximum size of sand is also important parameter in mortar. These parameters affect workability, strength and unitweight of mortar. In tills study, different sand gradings were used to investigate effects of fineness moduli of sand for examination about the workability, strength and unit weight characteristics of cement mortar. Two kinds of sands with various size distribution and three kinds of fine aggregates with the similar particle size distribution (Sieve No.16~30, No.30~50, No.50~100) were used. Water-cement ratio (W/C) of mortar mix was kept constant for all the trial mixes with sand of different fineness modulus. Major findings of tills study are: (a) Fine sand with the similar size distribution reduces the workability and unit weight of cement mortar. (b) The compressive strength of mortar is not sensitive to sand grading variations. (c) The compressive strengths at the age of 28 days range from 32.1 to 54.1 MPa. (d) The sand with standard modulus distribution has better positive effects on the properties of the mortar.