Effect of Mn and C on Age Hardening of Fe–Mn–Al–C Lightweight Steels

Sung‑Won Park,Jun Young Park,Kyong Mox Cho,Jae Hoon Jang,Seong‑Jun Park,Joonoh Moon,Tae‑Ho Lee,Jong‑Ho Shin 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.3

The effects of Mn and C content on the age hardening of Fe–Mn–Al–C lightweight steels, which have austenitic or duplex(austenite and ferrite) microstructures, were investigated. An increase in Mn content induced a delay of the age hardeningthat is caused by the formation of intra-granular κ-carbides. In order to interpret the effect of Mn content, first-principlescalculations were conducted using the supercells of Fe24Al8C8,Fe24Al8C7,Fe24(Al7Mn)C8, and Fe24(Al7Mn)C7. The calculationsshowed that an increase in Mn content could be the source of the delay of the intra-granular κ-carbide formation bysuppressing C atom’ occupation of the vacancy at the body-centered site of L12. An increase in C content accelerated theformation of intra-granular κ-carbides, which induced the intense age hardening, and coarse inter-granular κ-carbides, whichresulted in significant decrease in impact absorbed energy due to inter-granular fracture.

Inexplicable but real phenomenon: rapidly regressed

( Sung Min Park ),( Hyunju Jin ),( Hyang Suk You ),( Woo Haing Shim ),( Jeong Min Kim ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ),( Gun Wook Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Kaposi’s sarcoma (KS) is a type of spindle cell malignancy that arises from the vascular endothelium, usually presenting as violaceous papules and plaques. KS development is invariably linked with human herpesvirus (HHV)-8 infection. Almost spontaneous regressions of KS have been previously described in the iatrogenic type. Herein, we present a classic KS in immunocompetent patient showing rapid regression after biopsy. A 78-year-old male presented with relatively well-defined erythematous patches on forehead, Rt. upper eyelid and chin, and violaceous papule on nose. His medical and family histories were noncontributory. The patient denied history of recent overseas travel, homosexual or unnatural sexual practices, and serum anti-HIV antibody was negative. A histopathologic examination from the nose revealed typical findings of KS and tumor cells showed positive staining for CD31, CD34, and factor VIII-related antigen. Polymerase chain reaction in a biopsy specimen was positive for HHV-8. Without specific treatment, the lesion rapidly regressed within 2 weeks. It is generally accepted that immune status plays an important role for KS. As viral wart disappear after biopsy occasionally, it is possible that the biopsy may have then exposed antigens and induced an immunologic reaction, which led to the rapid regression of KS.

The use of ingenol mebutate gel as adjuvant therapy for large or multiple Bowen disease

( Sang Jin Cheon ),( Hyun Ju Jin ),( Hyang Suk You ),( Woo Haing Shim ),( Jeong Min Kim ),( Gun Wook Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ),( Hoon Soo Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Bowen disease (BD) is squamous cell carcinoma in situ, which may progress to invasive carcinoma if not adequately managed. In single and small BD, many therapeutic options are available including excision, curettage, cryotherapy, and topical agents such as 5-fluorouracil and imiquimod. But in the case with large or multiple lesions, therapeutic choice is restrictive. Herein, we experienced two cases of large or multiple BD successfully managed with ingenol mebutate gel. A 81-year-old woman was diagnosed as BD for large lesion on the right calf measuring 7 x 10 cm. We applied ingenol mebutate gel 0.05% on the affected area once daily for 2 consecutive days. 1 month after treatment, crust fell out and only focal small lesion was remained. After additional cryotherapy was done twice and clinically resolved large BD during follow-up 6 months.. A 54-years-old woman was diagnosed as BD for multiple hyperkeratotic plaques on the both palms. We applied ingenol mebutate gel 0.05% once daily for 2 consecutive days. After 3 months, only a few lesions were remained. Following three times additional cryotherapy, the lesions were improved enough to be controlled cryotherapy. Through our experience, we suggest ingenol mebutate gel could be effective adjuvant therapy option for large or multiple BD.

Cancer Cachexia in Pancreatic Cancer Patients: Recent Advances and New Therapeutic Approach

Sang Hoon Lee,Moon Jae Chung Korean Society of Gastrointestinal Cancer 2015 Journal of digestive cancer reports Vol.3 No.2

About 80% of all pancreatic cancer patients suffer from a wasting syndrome defined as the cancer cachexia characterized by abnormally low weight, weakness, and loss of skeletal muscle mass, which directly impacts physical activity, quality of life and overall survival. Over the past decades, we have gained new insights into the underlying mechanism of cachexia associated with pancreatic cancer. The aim of this review was to explore recent findings about cancer cachexia pathophysiology and describe the current pharmacologic approach. Pancreatic cancer cachexia is a multifactorial syndrome mediated by mechanical factors, inflammatory cytokines, neuropeptides, hormones and tumor-derived factors. The treatment of cancer cachexia remains controversial but is currently an active area of research. Several new targeted drugs are under investigation, and we hope to open a new prospect in the management of cancer cachexia in the future.

Mycoplasma pneumoniae -induced rash and mucositis

( Sung Min Park ),( Hyunju Jin ),( Hyang Suk You ),( Woo Haing Shim ),( Jeong Min Kim ),( Gun Wook Kim ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ),( Hyun Chang Ko ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Mycoplasma pneumoniae (M. pneumoniae)is one of the most common causes of respiratory tract infections in pediatric and adult populations worldwide. In dermatologic disorder, M. pneumoniae infection is known to be associated with erythema multiforme (EM) and Stevens-Johnson syndrome (SJS) in children and young adults. Recently, several cases with M. pneumoniae-associated mucositis with lacks typical target lesions have been reported. The term of Mycoplasma-induced rash and mucositis (MIRM) was suggested to revise from M. pneumoniae-associated mucocutaneous disease including EM and SJS because of distinct morphology, mild disease course, and potentially important clinical implications regarding treatment.Herein, we report a patient with MIRM. A 5-year-old boywas referred to the department of dermatology forerythematous maculopapuleson the face, trunk, and extremities. Physical examination revealed swollen eyelids with conjunctival injection, swollen lips, and erythematous erosive patch on the penile tip and perianal area.Histopathologic finding showed subepidermal blister with epidermal necrosis, and perivascular lymphohistiocytic infiltrations.Chest radiograph demonstrated localized infiltration in the right upper lobe, and M. pneumoniaeIgM antibodies was positive. Hewas treated with antibiotics, intravenous immunoglobulins, and showed rapid recovery within 2 weeks without any sequelae. Keyword: Mycoplasma pneumoniae, Mucositis, Rash, Stevens-Johnsons syndrome, Erythema multiforme

Automatic wavelength allocation method using Rayleigh backscattering for a WDM-PON with tunable lasers

Sang-Rok Moon,Hoon-Keun Lee,Chang-Hee Lee IEEE 2013 Journal of optical communications and networking Vol.5 No.3

<P>We propose an automatic wavelength control method using Rayleigh backscattering in a feeder fiber for tunable lasers employed in a wavelength-division multiplexing passive optical network. We demonstrate two realization methods, maximizing backscattered power and maximizing the second harmonic component with wavelength modulation. We analyze their limiting factors and impacts on the system performance. We use a VCSEL as a low-cost tunable light source.</P>

Combined Hepatocellular-Cholangiocarcinoma in Extrahepatic Bile Duct with Co-existing of Scirrhous Type of Hepatocellular Carcinoma

Sang Hoon Lee,Moon Jae Chung Korean Society of Gastrointestinal Cancer 2014 Journal of digestive cancer reports Vol.2 No.1

We report a patient with combined hepatocellular-cholangiocarcinoma confined in the common hepatic duct and scirrhous type of hepatocellular carcinoma in the caudate lobe of liver simultaneously. The patient was a 55-yearsold Korean man with hepatitis B virus (HBV) carrier who was referred from a local hospital due to detected liver mass on abdominal computed tomography (CT). He has presented jaundice and weight loss for the previous 3 weeks. Laboratory examination showed AST/ALT elevation and hyperbilirubinemia. HBsAg was positive. The tumor marker study showed elevated AFP and DCP, not CEA and CA 19-9. Abdominal CT disclosed an about 2.1×0.9 cm sized soft tissue density in hilum with both intrahepatic duct (IHD) dilatations and an about 3×2.1 cm sized arterial enhancing lesion at segment 8 of the liver. Patient received 15 cycles of Gemcitabine/Cisplantin chemotherapy from February 27, 2013 to December 31, 2013. Caudate lobectomy of liver, segmental resection of bile duct and Roux-en-Y hepaticojejunostomy was performed on February 10, 2014. The final pathologic report showed double primary liver cancer, combined hepatocellular-cholangiocarcinoma in common hepatic bile duct and scirrhous type of hepatocellular carcinoma in segment 1 of the liver. This is a very unusual case in which combined hepatocellular-cholangiocarcinoma confined in the large bile duct and two rare hepatic cancers coexisted.

Hangover Relieving Effect of Hovenia Dulcis and Sanghwang Mushroom Mycelium Cultured in Hordeum Vulgare

Sung Min Cho,Yoo Jin An,Hae Hee Moon,Dong Soo Park,Nam Gen Jeon,Young jae Lee,Chang Hoon Han 대한수의학회 2016 대한수의학회 학술대회발표집 Vol.2016 No.-

The Effect of Acts of Compassion Within Organizations on Corporate Reputation : Contributions to Employee Volunteering

Moon, Tae-Won,Ko, Sung-Hoon 대한경영정보학회 2017 경영과 정보연구 Vol.36 No.2

본 연구는 조직구성원들 사이에서 타인의 고통에 의해 유발되는 공감이 긍정적 조직정체성을 통하여 기업의 사회적 책임 활동에 대한 조직구성원들의 자발적 참여와 어떻게 연결되는지에 대한 이론적 고찰을 하고자 한다. 본 연구에서는 공감이 특별한 조직의 구성원이 되는 것과 관련 있는 긍정적 정체성을 유발시키게 되며, 긍정적 정체성이 기업의 사회적 책임에 대한 조직구성원들의 자발적 참여를 향상시켜 결국에는 기업의 명성을 강화시킨다는 것을 주장하고 있다. 또한, 강화된 기업의 이미지는 구축된 외부 이미지를 통하여 조직구성원들이 지각하는 조직 정체성을 향상시키는 결과를 가져온다. 높은 긍정적 조직 정체성을 지니고 있는 조직 구성원들은 조직 내 구성원들과 함께 나눔과 공감적 행위를 더 잘 실천하게 될 것이다. 결론적으로 기업의 사회적 책임활동에 대한 조직 구성원들의 자발적 참여와 공감 사이의 긍정적 순환 관계는 그림2에서 보여주고 있듯이 조직 구성원들 간의 공감적 행위가 긍정적 정체성을 통하여 기업의 사회적 책임에 대한 조직구성원들의 자발적 참여를 불러일으키게 된다는 것이다. 또한 그 뿐만 아니라 기업의 명성을 강화시킨다는 측면에서 어떻게 기업의 사회적 책임에 대한 조직구성원들의 자발적 참여가 조직 내 공감적 행위를 유발시킬 수 있을 것인지 그림2가 설명해 주고 있다. This paper explores a theoretical framework, in which compassion arising from others’ suffering among organizational members can be connected to EV to CSR activities via POI. We argue that compassion may generate positive identity related to being a member of a particular organization (i.e., POI), which increases to EV to CSR, ultimately leading to the enhancement of the corporate reputation. In return, an enhanced reputation for the corporation results in an increase of employees' perceived organizational identity via increase of CEI. Employees with high POI are more likely to carry out compassion and share it with others within an organization. In short, the positive circulation between compassion and EV to CSR as shown in Figure 2 demonstrates not only the ways in which compassion among organizational members can evoke EV to CSR through POI, but also how EV to CSR can facilitate compassion within an organization in terms of enhanced corporate reputation.

LOW TEMPERATURE DEPOSITION OF CRYSTALLINE SILICON BY HCL ADDITION DURING HOT WIRE CHEMICAL VAPOUR DEPOSITION

Sang-Hoon LEE,Yung-Bin CHUNG,Jae-Soo JUNG,Nong-Moon HWANG 한국신재생에너지학회 2011 AFORE Vol.2011 No.-