고온 환경에서의 운동 시 서로 다른 수분 보충이 엘리트 운동선수들의 염증성 사이토카인 반응 및 면역 기능에 미치는 영향

백일영 ( Il Young Paik ),윤두상 ( Doo Sang Yun ),서상훈 ( Sang Hoon Suh ),노희태 ( Hee Tae Roh ) 한국스포츠정책과학원(구 한국스포츠개발원) 2011 체육과학연구 Vol.22 No.3

이 연구의 목적은 고온 환경에서의 운동 시 단순 수분 및 스포츠 음료를 통한 수분 보충이 엘리트 운동선수들의 호르몬 변화, 염증성 사이토카인 반응 및 면역 기능에 미치는 영향을 규명하는데 있다. 연구의 대상은 엘리트 운동선수 10명으로 하였으며, 4가지 실험 처치 조건에서 75%HRR 운동 강도로 60분간 트레드밀 달리기를 실시하였다: 1) 적정 환경에서 운동 처치 조건(TE), 2) 고온 환경에서 운동 처치 조건(HE), 3) 고온환경에서 운동 시 물 섭취 처치 조건(HW), 4) 고온 환경에서 운동 시 스포츠음료 섭취 처치 조건(HS). 기후조건은 인공기후실을 이용하여 적정 환경은 온도 18℃, 상대습도 50%로 설정하였으며, 고온 환경은 온도 32℃, 상대습도 50%로 설정하였다. 수분 보충은 물 또는 스포츠음료를 이용하여 고온 환경에서 운동 처치 조건(HE)의 운동 전, 후 체중 차와 동일한 양을 구강 투여하였다. 채혈은 안정 시, 운동 직후, 회복 60분 시점에서 실시하였다. 연구결과, 운동 직후 시점에서 epinephrine은 HE 처치가 다른 세 처치(TE, HW, HS)보다 유의하게 높았으며(p<.05), norepinephrine은 HE 처치가 TE 처치보다 유의하게 높았다(p<.05). IL-6는 운동 직후 시점에서 HE 처치가 TE 처치보다 유의하게 높았다(p<.05). TNF-α는 TE 처치를 제외한 세 처치(HE, HW, HS)에서 운동 직후 유의하게 증가하였다(p<.05). T-cell은 TE 처치를 제외한 세 처치(HE, HW, HS)에서 운동 직후 유의하게 증가하였으며(p<.05), HE 처치가 TE 처치보다 유의하게 높았다(p<.05). NK-cell은 운동 직후 시점에서 HE 처치가 TE 처치보다 유의하게 높았다(p<.05). Neutrophil은 HE 처치의 경우 운동 직후 시점에서 유의하게 증가하였다(p<.05). Lymphocyte는 TE와 HE 처치에서 운동 직후 유의하게 증가하였다(p<.05). Monocyte는 운동 직후 시점에서 HE 처치가 TE 처치보다 유의하게 높았다(p<.05). 이상의 결과를 종합하면, 고온 환경에서의 운동은 적정 환경에서의 운동 시보다 카테콜아민과 염증성 사이토카인의 분비를 증가시켜 면역기능에 부정적인 영향을 미칠 수 있는 것으로 나타났다. 반면에 고온 환경에서의 운동 시 수분 보충은 탈수와 열적 스트레스를 경감시켜 면역기능의 부정적 영향을 완화시킬 수 있음을 시사한다. The purpose of the current research was to investigate the effects of body fluid replacement by water or sport drinks on the hormonal, inflammatory cytokine and immune responses during exercise in high ambient temperature. The subjects of the current research were 10 elite athletes. The subjects were asked to perform treadmill running at 75%HRR for 60 minutes in four different conditions, controlled by the environmental chamber: 1) thermoneutral environment (TE), 2) high ambient temperature environment (HE), 3) high ambient temperature environment and body fluid replacement by water (HW), and 4) high ambient temperature environment and body fluid replacement by sport drink(HS). Ambient temperature and relative humidity were set at 18℃ and 50%, respectively, for the theromoneutral environment, and 32℃ and 50% for the high ambient temperature environment. The amount of fluid replaced during two different fluid replacing conditions (HW and HS) were equivalent to the difference in body weight between pre and post completion of the running in HE. The defined amounts of the fluids were administered orally with separations during the exercise trials. Blood samples were taken at rest, at immediately after exercise, and at 60-minute of recovery. For catecholamine responses, the level of epinephrine immediately after exercise appeared to be significantly higher in HE compared to the other treatment conditions (p<.05), while the level of norepinephrine appeared to be significantly higher in HE compared to TE (p<.05). For cytokine responses, the level of IL-6 immediately after exercise appeared to be significantly higher in HE compared to TE (p<.05) while the levels of TNF-α were shown to significantly increase at immediately after exercise in all treatment conditions except TE (p<.05). For immune responses, the levels of T-cell were shown to significantly increase at immediately after exercise in all treatment conditions except TE (p<.05), and the level appeared to be significantly higher in HE compared to TE (p<.05); the level of NK-cell appeared to be higher at immediately after exercise in HE compare to TE (p<.05); the level of neutrophil was shown to significantly increase at immediately after exercise in HE (p<.05); the levels of lymphocyte were shown to significantly increase in TE and HE at immediately after exercise (p<.05); and the level of monocyte appeared to be significantly higher in HE compared to TE at immediately after exercise (p<.05). On the base of the results of the current study, it is suggested that exercise in high ambient temperature can induce increase responses of catecholamines and cytokines which may negatively influence on immune functions. Body fluid replacements during exercise in high ambient temperature, however, can attenuate the negative consequences of thermal stress on immune functions by preventing dehydration and reducing thermal stress.

냄새제거용 첨착활성탄 개발에 관한 연구

노성희,차진명,김선일 한국공업화학회 2005 응용화학 Vol.9 No.1

In this study, we developed impregnated activated carbon manufacturing process, and investigated the possibility of using coconut as a activated carbon for odor removal. Among the five collectors, KCI, NaOH, Ki, HNO₃, and H₂SO₄, that were added to the adsorption process for the odor removal of H₂S and NH₃, the treatment with H₂SO₄ showed the best result having the adsorption quantity of 4.6 mg/g.

응집제 첨가 활성슬러지법과 침지형 막분리의 혼성공정에 의한 폐수처리에 관한 연구

노성희,김선일 한국공업화학회 2003 응용화학 Vol.7 No.2

This study focused on a submerged membrane bioreactor in conjunction with coagulant addition coagulant. such as alum in order to improve treatment efficiency. especially phosphorus removal and to removed by biological, chemical reaction and membrane separation mechanism. As the result of dosing alum into MBR, flux was stable and permeate pressure was bring down remarkably.

광중합형 레진에서 초기 저광도 광중합 및 연마 시기가 변연부 미세 누출에 미치는 영향

노병덕,정일영,이상훈 大韓齒科保存學會 2000 Restorative Dentistry & Endodontics Vol.25 No.1

폐석회 담체를 이용한 고정생물막 공정에서의 영양염류 제거

노성희,김선일 한국공업화학회 2003 응용화학 Vol.7 No.1

This study was performed to investigated the possibility of using waste lime as a support carrier for wastewater treatment. Cubic type support carriers were prepared as follows : ① mixing in water (waste lime, curdlan) ② pH contorl(pH12 →pH 7) ③heating (120℃, 30min) ④dehydrating using freeze dryer. In the case of filing support carrier high removal efficiencies of 25% were developed waste lime support carrier were confirmed in this test.

백서의 일과성 국소허혈-재괄류 모델에서 U-74389G와 MK-801이 뇌경색 크기에 미치는 효과

김재일,김종민,양대웅,이근호,윤병우,노재규,이상복 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

폐석회 담체를 이용한 MBR공정에서 영양염류 제거 특성

노성희,김선일 한국공업화학회 2005 응용화학 Vol.9 No.1

In this research, we developed support carrier manufacturing process, very economical and increased porosity and surface roughness. We used waste lime to do disposed which currently rapidly increased to make support carrier. The manufactured support carrier was used for nutrient removal and its removal efficiency was also investigated. Nutrients removal efficiency increased with the increase of support carrier volume fraction.

염색폐수 처리를 위한 부상공정에서 아민투여량과 pH의 영향

노성희,차종희,김선일 조선대학교 생산기술연구소 2006 生産技術硏究 Vol.28 No.2

The removal of colours from aqueous solution and dispersions has been studied by dispersed-air flotation, in a semi-batch column. Two colours were used for the experiments: Basic Yellow 28 (basic) and Direct Orange 31 (basic). All two were effectively removed by flotation within 8 min. Sodium dodecyl sulfate, sodium oleate and amines were found to be effective as collectors in the removal of colour, which was found to be related to the pH of the solution and the amount of collector added to it with high collector dosages causing the process to become pH-independent.

비뉴턴 유체의 협착관 및 분기관내 거동

서상호,노형운,장남일,유상신 崇實大學校 生産技術硏究所 1993 論文集 Vol.23 No.-

The numerical analysis is applied to laminar flow in the stenosed and bifurcated tubes. The objective of this study is to determine the influence of diameter ratio, stenosis, spacing, number of stenosis and Reynolds number on flow characteristics in the periodic stenosed tubes and the effect of flow parameters on the flow behaviors in daughter branches of bifurcation. The analysis is extented to predict the flow characteristics in non-Newtonian flow fields.

유효미생물을 이용한 SBR 공정에서 생물학적 영양염 제거에 관한 연구

김선일,노성희 조선대학교 생산기술연구소 2003 生産技術硏究 Vol.25 No.1

This study was carried out to compare the efficacy of wastewater treatment by activated sludge and EM(Effective Microorganisms) The treatment of wastewater was performed using 1%(v/v) EM in the glass reactor(3L). The SBRs(sequencing batch reactors) were fed synthetic wastewater and operated on a cycle consisting of the following phases 30min fill, 3hr anaerobic, 14hr aerobic, 4hr anoxic, 2hr settling, 30min draw. Nitrogen and phosphorus removal efficiency were about 98%, 92%, respectively in the EM-received reactor. The almost identical performance achieved with EM in comparison to activated sludge.