Maternal and neonatal adverse outcomes following induced labor in women with a long cervix comparing in women with a short one

( Su Bin Jo ),( Eui Hyeok Kim ),( Keum Seon Son ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: To evaluate maternal and neonatal adverse outcomes following induced labor in women with a long cervix comparing women with a short one Methods: This was a retrospective observational study of singleton, vertex-presenting women from 37 0/7 to 41 6/7 weeks of gestation who were delivered following induced labor. After induced labor, outcomes in women with a favorable cervix (cervical length was 3 cm or more) were compared with a unfavorable one (cervical length was less than 3 cm). Results: A total of 422 women were attempted induced labor. Of these, the number of women with cervical length more than 3 cm or more was 49 and the 373 had a cervix less than 3 cm. We found no significant difference in the overall cesarean rate and the blood loss during the delivery (16.3% vs. 11.5%, p=0.333, 1.5±1.5 mg/dl vs. 1.6±1.3 mg/dl, p=0.460, respectively). Delivery time and the rate of delivery within 12 hours from induction labor were also similar between the two groups (797±597 min Vs. 661±495 min, p=0.107, 65.9% vs. 70.0%, p=0.586). Regarding neonatal outcomes, the rate of meconium-stained amniotic fluid, Apgar score < 7 at 5 minutes and intubation were similar between the two groups (12.2 % vs. 10.2 %, 2.0% vs. 6.7% , 6.1 % vs. 3.8% , respectively, all p > 0.05). There was no cesarean hysterectomy and perinatal death in this study. Conclusion: We found no evidence that induced labor with an unripen cervix increases adverse maternal outcomes including the cesarean rate or compromises neonatal outcomes as compared with a ripen one.

두 개의 임플란트를 이용한 3본 고정성 국소의치에서 가공치 위치에 따른 하악골에서의 응력 분포 및 변형에 관한 삼차원 유한요소법적 연구

김동수(Dong-Su Kim),김일규(Il-Kyu Kim),장금수(Keum-Soo Jang),박태환(Tae-Hwan Park),김규남(Kyu-Nam Kim),손충렬(Choong-Yul Son) 대한구강악안면외과학회 2009 대한구강악안면외과학회지 Vol.34 No.2

Excessive concentration of stress which is occurred in occlusion around the implant in case of the implant supported fixed partial denture has been known to be the main cause of the crestal bone destruction. Therefore, it is essential to evaluate the stress analysis on supporting tissue to get higher success rates of implant. The purpose of this study was to evaluate the effects of stress distribution and deformation in 3 different types of three-unit fixed partial denture supported by two implants, using a three dimensional finite element analysis in a three dimensional model of a whole mandible. A mechanical model of an edentulous mandible was generated from 3D scan, assuming two implants were placed in the left premolars area. According to the position of pontic, the experiments groups were divided into three types. Type I had a pontic in the middle position between two implants, type II in the anterior position, and type III in the posterior position. A 100-N axial load was applied to sites such as the central fossa of anterior and posterior implant abutment, central fossa of pontic, the connector of pontic or the connector between two implants, the mandibular boundary conditions were modeled considering the real geometry of its four-masticatory muscular supporting system. The results obtained from this study were as follows; 1. The mandible deformed in a way that the condyles converged medially in all types under muscular actions. In comparison with types, the deformations in the type II and type III were greater by 2-2.5 times than in the type I regardless of the loading location. 2. The values of von Mises stresses in cortical and cancellous bone were relatively stable in all types, but slightly increased as the loading position was changed more posteriorly. 3. In comparison with type I, the values of von Mises stress in the implant increased by 73% in Type II and by 77% in Type III when the load was applied anterior and posterior respectively, but when the load was applied to the middle, the values were similar in all types. 4. When the load was applied to the centric fossa of pontic, the values of von Mises stress were nearly 30-35% higher in the type III than type I or II in the cortical and cancellous bone. Also, in the implant, the values of von Mises stress of the type II or III were 160 -170% higher than in the type I. 5. When the load was applied to the centric fossa of implant abutment, the values of von Mises stress in the cortical and cancellous bone were relatively 20-25% higher in the type III than in the other types, but in the implant they were 40-45% higher in the type I or II than in the type III. According to the results of this study, musculature modeling is important to the finite element analysis for stress distribution and deformation as the muscular action causes stress concentration. And the type I model is the most stable from a view of biomechanics. Type II is also a clinically acceptable design when the implant is stiff sufficiently and mandibular deformation is considered. Considering the high values of von Mises stress in the cortical bone, type III is not thought as an useful design

얼음입자추출법을 이용한 알부민 함유 PLGA 담체의 제조 및 방출 거동

서광수(Kwang Su Seo),김순희(Soon Hee Kim),김선경(Sun Kyung Kim),강길선(Gil Son Khang),신형식(Hyung Sik Shin),김문석(Moon Suk Kim),이해방(Hai Bang Lee),홍금덕(Keum Duck Hong) 한국고분자학회 2005 폴리머 Vol.29 No.3

온도 감응성 MPEG-PCL 하이드로젤을 이용한 단백질의 서방화

서광수 ( Kwang Su Seo ),홍금덕 ( Keum Duck Hong ),현훈 ( Hoon Hyun ),김문석 ( Moon Suk Kim ),강길선 ( Gil Son Khang ),이해방 ( Hai Bang Lee ) 한국조직공학과 재생의학회 2005 조직공학과 재생의학 Vol.2 No.2

The temperature sensitive hydrogels were synthesized by the terminal alcohol of methoxy poly(ethyleneglycol) (MPEG) as an initiator via ring-opening of ε-caprolactone (ε-CL) in the presence of HCl·Et2O as a monomer activator. The gel-to-sol transitions of MPEG-PCL diblock copolymer solutions were also examined in deionized water according to polymer concentration. The MPEG-PCL block copolymers were dissolved in water at 80oC and stored at 4oC for 15 hours. The polymer solutions formed sol around at the room temperature. The formed sol became gel from 31oC to 53oC by increasing the temperature. To observe the release behavior of protein based on MPEG-PCL block copolymers, hydrogels loaded proteins such as albumin, insulin, and dextran were easily fabricated by mixing polymer solution and proteins. The release profile of proteins in MPEG-PCL hydrogels showed the sustained zero-order release without initial burst for 20 days. In conclusion, we confirmed that MPEG-PCL temperature sensitive hydrogels is useful as controlled protein carriers.

인적행위개선 포스터 개발과 활용

권순일,손금수,정연섭,고효제,Kwon, Soon-Il,Son, Keum-Su,Jung, Yeon-Sub,Ko, Hyo-Je 대한인간공학회 2007 大韓人間工學會誌 Vol.26 No.1

As many as 111 reactor trips have occurred for recent 5 years('01-'05), and 26 cases of them have occurred due to human error. The trend of human error rate didn't decrease in 2004, so KHNP started to make efforts to decrease human errors. In 2006 KHNP bench marked excellent foreign nuclear power plants and introduced human error prevention tools. In addition, KHNP created as many as 40 posters for human performance improvement. The posters are based on the about 500 real incident reports collected through K-HPES from 1995. Therror preventive tols for the poster. This paper explains design of the posters and their application.

쯔쯔가무시병에 동반된 다발성 근염 1 예

이성원,정원태,우영석,손춘희,장채령,정승수,금동주,장광열 대한내과학회 2001 대한내과학회지 Vol.61 No.3

We report the case of a 32-year-old female who developed polymyositis associated with scrub typhus. She exhibited the eschar with high titer of anti-Rickettsia(R)-tsutsugamushi antibody, severe muscle weakness, markedly elevated serum levels of muscle enzymes, EMG changes, and infiltration of macrophages in a muscle biopsy specimen. Initiation of appropriate antibiotic therapy resulted in complete healing of scrub typhus and disappearance of symptoms and signs of polymyositis within 1 month after high dose steroid therapy. We suggest that scrub typhus also be included within the causes of idiopathic inflammatory polymyositis. (Korean J Med 61:298-301, 2001)