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      • The Media Literacy of Residents in Southwestern China During the COVID-19 Epidemic

        Shan He(Shan He),Lili Yao(Lili Yao),Xingyu Zhao(Xingyu Zhao),Weiwei Liu(Weiwei Liu) 아시아사회과학학회 2023 International Science Research Vol.3 No.2

        Objective To measure residents’ abilities to acquire, analyze and evaluate information on media in southwestern China and to explore its predictive factors. Methods The convenience sampling method was used. A web-based questionnaire survey was conducted among 774 residents during the Spring Festival in 2020. Results Young, highly educated, unmarried, high-income, and urban residents preferred to seek and acquire information about COVID-19 epidemic through new media channels. Elderly residents tended to obtain information through television. Residents with low educational background and rural residents were more dependent on community information media. To analyze residents’ abilities in the judgement of 15 statements about COVID-19, residents with a master’s degree or above (OR = 2.755, [95% CI 1.160-6.542]) had better media literacy in identifying false health information released on social networking. Rural residents (OR = 0.609, [95% CI 0.433-0.855]) had lower media literacy. The total score decreased by 2.6% for every one-year increase of age. Conclusion Residents’ abilities to acquire, analyze and evaluate information were affected by their demographic characteristics in southwestern China. The authorities and local communities should develop different approaches of information dissemination, with the help of traditional and new media. It is important to improve the level of residents' media literacy, in order to achieve better effect in information dissemination and reception.

      • KCI등재

        "선녀결연 설화"의 유형과 전승 양상 -중(中),한(韓) <견우와 직녀>와 <나무꾼과 선녀>를 중심으로

        조산산 ( Shan Shan Zhao ) 한국비교문학회 2010 比較文學 Vol.51 No.-

        Both in Korea and China, there is a custom of July 7 in the lunar calendar, or Qixi, and its fairy-tale that has been passed on orally. Through the world, there are "Swan-maiden Tales"-type-stories; The Angel(Young goddess) and the woodcutter tale represents that of Korea, and there are many types of tales in China. Such being the case, in this paper it goes by the name of "The Angel and the woodcutter tale." In China, there are two types of tales relating "July 7 in the lunar calendar", and one of them is similar to the tale of "Gyonu and Jingnyo." The love story between the two who are destined to meet each year on the 7th of the 7th lunar month"(The Double-Seventh Day). The story is, however, about to vanish. Another type of is the tale is "Niu Lang (Cowherd) and a fairy from heaven Zhi Nu (Weaver Maid)" which is a combination of the two stories of "Gyonu and Jingnyo" and that of "The Angel and the woodcutter." On the contrary, in Korea, the upper-mentioned two fairy-tales exist separately respectively, the two stories of "Gyonu and Jingnyo" and that of "The Angel and the woodcutter." That is, there is no type of the combination of the two stories. In China, there are three-type-of tale, namely, "Gyonu and Jingnyo" and that of "The Angel and the woodcutter, and its combination form as well. The combination is said to have been the universal stories of "The Four Legendary Tales." The tales of every three types is the one motivated by the twinning of the man and young goddess. This paper is to explore the characteristic of the transmission of the tales by comparing the transmitting procedures of the tales of Korea and China respectively. In so doing, the paper is to exploit the inevitability suggesting that the tale of "Niu Lang and Zhi Nu" has been developped into universal stories in China.

      • KCI등재

        한·중 ‘선녀결연 설화’의 유형분류와 의미

        趙??(Zhao, Shan-Shan) 고려대학교 한국학연구소 2013 한국학연구 Vol.46 No.-

        ‘선녀결연 설화’는 여기서 ‘牽牛와 織女 설화’, ‘나무꾼과 선녀 설화’, ‘牛郞과 織女 설화’ 세 기본 유형을 가리킨다. 필자는 세 설화 유형이 각각 독립된 유형이라고 주장한다. 이 주장의 성립을 위해 던데스의 구조유형분류 방법을 적용해서 ’선녀결연 설화’를 다시 분류하자고 한다. 세 설화 유형이 ’만남’과 ’이별’의 같은 서사구조에 드러나는 결연은 한국과 중국에서 다양한 변이양상을 보인다. 따라서 주인공의 성격변화, 천상과 지상의 행복지향성, 조력자의 기능, 방해자의 갈등표출 등 4 가지 면에서 그 변이양상과 의미를 고찰하자고 한다. ‘Twinning of Heavenly Maiden tales’ are usually related to the three widely-spread stories in Korea and China, namely, Romantic Altir and Vega, Woodman and Fairy, and Cowherd and Weaver Girl. I think these two viewpoints have some shortcomings to some extent, and hold the view that they should be studied as a relatively independent genre. Therefore, in this thesis, Mr. Alan Dundes’ classification method is adopted for classifying passages of ‘Twinning of Heavenly Maiden tales’. These 3 categories of stories are all related to the ‘Twinning of Heavenly Maiden tales’ and are characteristic of sacred marriage. In each category, especially in the Romantic Love of Altir and Vega, along with the frequent interchange of both hero and heroine from heaven to earth, and the continuing increase and overlap of the two common motifiemes of encountering by chance and farewell, the story plots also evolved into many variations in the course of spreading in Korea and China, which could be seen from 4 aspects including the characters of both hero and heroine, happiness target of space/background movement, role of supporters, and ambivalent action of the trouble-makers.

      • Expression of Connexin 43 and E-cadherin Protein and mRNA in Non-small Cell Lung Cancers in Chinese Patients

        Zhao, Jun-Qiang,Sun, Fang-Jie,Liu, Shan-Shan,Yang, Jun,Wu, Yu-Quan,Li, Gui-Shan,Chen, Qing-Yong,Wang, Jia-Xiang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Aim: Connexin 43 (Cx43) and E-cadherin are important biomarkers related with cancer. Their expression at protein and mRNA levels was here investigated in 50 primary lung carcinoma tissues and 20 samples of adjacent normal tissue of Chinese patients with non-small cell lung cancer (NSCLC). Methods: Protein and mRNA expression were evaluated by ABC immunohistochemistry and RT-PCR. Results: (1) The positive expression rates of Cx43 and E-cadherin protein were higher in the adjacent normal tissues than those in the primary lung carcinoma tissues; (2) the positive expression rates of Cx43 and E-cadherin protein decreased with NSCLC progression; (3) the expression of E-cadherin protein was not related with the pathological type of NSCLC; and (4) the relative quantity of the Cx43 or E-cadherin mRNA expression was correlated with the the histological type, clinical stage, cancer cell differentiation and the lymph node metastasis. Conclusion: The data suggested that the Cx43 and E-cadherin are reduced with NSCLC progression, and might be important biomarkers for judging the metastasis and prognosis.

      • Aberrant Expression of miR-20a and miR-203 in Cervical Cancer

        Zhao, Shan,Yao, De-Sheng,Chen, Jun-Ying,Ding, Nan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

        MicroRNAs (miRNAs) are small, non-coding RNAs that are critical regulators of various diseases. MicroRNA-20a (miR-20a) and microRNA-203 (miR-203) have previously shown significant alteration in a range of cancers. In this study, the expression levels of miR-20a and miR-203 in 100 cervical cancer tissues were detected by qRT-PCR and compared to patient matched-nontumor cervical tissues. Correlations between expression level and clinicopathologic characteristics of cervical cancer were also analyzed. Finally, we studied the effect of miR-20a and miR-203 on cell proliferation in cervical cancer cell lines by MTT. We found that the expression level of miR-20a (P<0.001) was significantly higher in cervical cancer patients than in healthy controls, while that of miR-203 (P<0.001) was lower. Aberrant expression of miR-20a was correlated with lymph node metastasis (LNM), histological grade and tumor diameter, but down-regulated miR-203 was correlated with LNM only. Furthermore, we found that over-expression of miR-203 decreased cell proliferation, while reduction of miR-20a also prevented tumor progression. Our results support the involvement of miR-20a and miR-203 in cervical tumorigenesis. We propose that miRNAs might be used as therapeutic agents for cervical cancer.

      • KCI등재

        Thermal and mechanical properties of poly(latic acid) reinforced with silanized basalt scales

        Shan-Shan Yao,Ming-Zhan Gao,Zhao-Yang Feng,Fan-Long Jin,박수진 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.7

        Biodegradable poly(lactic acid) (PLA)-based composites were prepared using PLA and basalt scale (BS) viaa solution-blending method. BS surfaces were treated using a silane coupling agent, and their surface properties werecharacterized by high-resolution scanning electron microscopy, energy-dispersive X-ray spectrometry, and X-ray photoelectronspectrometry. Moreover, the influence of BS content on the thermal properties, flexural properties, impactstrength, and morphology of the PLA/silane-coupling-agent-treated BS (KH-BS) composites was analyzed. The thermalstability of the composites significantly increased due to the addition of KH-BS. Impact strength tests showed thatthe impact strength of the PLA/KH-BS composite with 4 wt% KH-BS was 3.14 kJ/m2, which is 51% higher than that ofpristine PLA (2.07 kJ/m2). The analysis of the fracture surfaces of the composites after the impact strength tests revealeda rough morphology with numerous river-like micro-cracks. The study results demonstrate that the addition of KH-BSsignificantly improves the thermal stability and impact strength of PLA/KH-BS composites.

      • Effects of Valproic Acid on Proliferation, Apoptosis, Angiogenesis and Metastasis of Ovarian Cancer in Vitro and in Vivo

        Shan, Zhao,Feng-Nian, Rong,Jie, Geng,Ting, Zhou Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

        Inhibitors of histone deacetylase activity are emerging as a potentially important new class of anticancer agents. In this study, we assessed the anticancer effects of valproic acid (VPA) on ovarian cancer in vitro and in vivo. Cultured SKOV3 cells were treated by VPA with different concentrations and time, then the effects on cell growth, cell cycle, apoptosis, and related events were investigated. A human ovarian cancer model transplanted subcutaneously in nude mice was established, and the efficacy of VPA used alone and in combination with diammine dichloroplatinum (DDP) to inhibit the growth of tumors was also assessed. Proliferation of SKOV3 cells was inhibited by VPA in a dose and time dependent fashion. The cell cycle distribution changed one treatment with VPA, with decrease in the number of S-phase cells and increase in G1-phase. VPA could significantly inhibit the growth of the epithelial ovarian cancer SKOV3 cells in vivo without toxic side effects. Treatment with VPA combined with DDP demonstrated enhanced anticancer effects. The result of flow cytometry (FCM) indicated that after VPA in vitro and in vivo, the expression of E-cadherin was increased whereas vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) were decreased. This study suggests that VPA could be a novel attractive agent for treatment of ovarian cancer.

      • Performance of the R-way Colposcopic Evaluation System in Cervical Cancer Screening

        Zhao, Jian,Zhang, Xi,Chen, Rui,Zhao, Yu-Qian,Wang, Ting-Ting,He, Shan,Qiao, You-Lin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10

        Objective: To investigate the diagnostic value of the R-way colposcopic evaluation system (R-way system) in cervical cancer screening. Materials and Methods: Between August 2013 and August 2014, a total of 1,059 cases referred to colposcopy in Peking University First Hospital were studied using both the R-way system and conventional colposcopy. Our study evaluated and compared the diagnostic ability of the two methods in detecting high-grade lesions and cervical cancer (hereinafter called CIN2+). Evaluation indicators including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), Youden index and the area under the curve (AUC) of the receiver operating characteristic (ROC) were calculated. Results: The R-way system had a slightly lower specificity (94.5%) than conventional colposcopy (96.0%) for CIN2+ detection (P=0.181). However, the sensitivity (77.8%) was significantly higher than with the conventional colposcopic method (46.6%) (${\chi}^2=64.351$, P<0.001). In addition, the AUC of the ROC for CIN2+ detection using the R-way system (0.839) was larger than that with conventional colposcopy (0.731) (Z=4.348, P<0.001). If preliminary result had been drawn from cervical exfoliated cytology before colposcopy referral, combination of the R-way system with cytology could increase the sensitivity to 93.9% for CIN2+ detection (excluding ASCUS\LSIL), confirmed by multipoint biopsy or ECC. Conclusions: The diagnostic value of the R-way evaluation system is higher than that of conventional colposcopic evaluation in cervical cancer screening. Moreover, taking the ease of use and standardized quality control management into account, the R-way system is highly preferable.

      • KCI등재

        Comprehensive approach to controlling chronic hepatitis B in China

        Shan Shan,Xinyan Zhao,Jidong Jia 대한간학회 2024 Clinical and Molecular Hepatology(대한간학회지) Vol.30 No.2

        Hepatitis B virus (HBV) infection was highly endemic in China, where the prevalence of HBsAg was 9.7% in 1992. Comprehensive strategies, including universal infant hepatitis B vaccination with emphasis on timely birth-dose and 3-dose coverage, dramatically reduced the mother-to-infant transmission and early childhood acquisition of HBV, resulting in estimated HBsAg prevalence rates of 5.6% and 0.1% in the general population and among children aged <5 years in 2022, respectively. Clinical guidelines on the prevention and treatment of chronic hepatitis B have been periodically updated based on emerging evidence from clinical research. The continuously improved reimbursement policy and the massively reduced price of antiviral drugs through government negotiation and central procurement have increased treatment accessibility and affordability. However, due to the low rates of diagnosis and treatment, China still faces a large challenge in achieving the 2030 goal of lowering HBV-related mortality by 65%. A public health approach involving concerted efforts from the government, medical community, industry, and society as a whole would be necessary to increase the uptake of HBV tests and treatment to achieve the global goal of eliminating viral hepatitis as a public health threat by 2030.

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