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양대현,범희승,최성규,유종선,박해옥,조정곤,윤종만 대한소화기내시경학회 1988 Clinical Endoscopy Vol.8 No.1
The records of 34 patients with histologically proven pm-gastric cancer were reviewed from Chonnam University Hospital during the recent 6 year period, 1981, to 1986. The male outnumbered female in a ratio of 2.4:1.0. The peak incidence was 6th decade and mean age were 53.8 years in male, 48.7 years in female respectively. pm-gastric cancer was most often seen on the lesser curvature side, eapecially in the lower 1/3 of the stomach. Macroscopically, it can be divided into early-cancer-like type and Borrmann type. Early-cancer-like type was more frequent than Borrmann type. Early-cancer-like type IIc+III was most often seen with a rate of 20.6%, followed in the order of frequency by Borrman type II, early-cancer-like type IIc, IIa+IIc, and Ile+ IIa. The incidence of lymph node involvement was 26.4% and were related to the macroscopic types and/or histologic differentiation degrees. 5 cases out of 34 pm-gastric cancer expired during the follow up period, and their mean survival time was 32.8 months. The type of operation and the extent of resection were closely related to survival. Five year survival rate was 54.0%. These results shows the significance of the pm-gastrie cancer as a early simulating advanced cancer.
위궤양에 대한 Teprenone ( Selbex ) 의 효과
윤종만(Chong Mann Yoon),범희승(Hee Seung Bom),최성규(Sung Kyu Choi),박일종(Il Chong Park),박해옥(Hae Ok Park),류종선(Jong Sun Rew),양대현(Dae Hyun Rang),조정곤(Jong Kon Cho) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
The balance of mucosal defensive factors and aggressive factors is important for ulcerogenesis. Gastrointestinal mucus is a complex glycoprotein which is secreted from variable types of cells in the gastrointestinal tract. Glycoprotein plays an important role as a mucosal defensive factor.We have treated 30 cases of endoscopically diagnosed gastric ulcers with teprenone (Selbex) for the evaluation of the therapeutic efficacy. Every patient was treated with teprenone 50 mg t.i.d. for 8 weeks and underwent endoscopic, clinical and laboratory assessments before and after 8 weeks of the treatment. Aiajor symptoms of gastric ulcer have been improved in 2 out :30 cases (83.4%) after 8 weeks of the medication with teprenone. While, the improvement of gastric ulcer evaluated by endoscopy was observed in 21 out of 30 cases (70.0%). No significant side effects were observed except a mild elevation of SGOT in one patient.
각종 간질환에서 혈청 Adenosine Deaminase 활성도
최성규(Sung Kyu Choi),양대현(Dae Hyun Yang),조정곤(Jong Kon Cho),박해옥(Hae Ok Park),박일종(Il Jong Park),범희승(Hee Seung Bom),류종선(Jong Seon Rew),윤종만(Chong Mann Yoon) 대한내과학회 1988 대한내과학회지 Vol.34 No.5
N/A To evaluate the clinical significance of serum ADA activity, serum ADA acitivities and their correlation with other liver function tests were analyzed in various hepatitic diseases, Sera of 30 normal adults, 18 patients with acute viral hepatitis R, 3 fulminant hepatitis, 13 chronic persistent hepatitis, 17 chronic active hepatitis, 47 liver cirrhosis, 15 primary hepatoma and 7 metastatic hepatoma were analyzed with colorimetric method of Guisti for serum ADA activity. The result obtained are as follows 1) In normal adults, the mean value of serum ADA activity is 18.84±4,00 U/L. 2) The mean value of serum ADA activity are 48,94±14.68 U/L in acute B viral hepatitis, 40.14±14.20 U/L in chronic persistent hepatitis, 56.02±3.61 U/L in chronic active hepatitis, 60.31±23.22 U/L in liver cirrhosis, 45. 82±21.09 U/L in primary hepatoma, 26.67±9.01U/L in metastatic hepatoma. There is significant difference between normal and various hepatic diseases. But there is no significant difference among various hepatic diseases. 3) There is no significant correlation between serum ADA activity and liver function test(AST, ALT, ALP) in various hepatic diseases. 4) In acute viral hepatitis B, serum ADA activity is decreased with time lapse. And as liver function test returns to normal, serum ADA activity is also normalized. 5) In one expired cases of fulminant hepatitis, serum ADA activity is decreased before death, while other liver function test (AST, ALT) are not reduced. But, in survived cases serum ADA activity and other liver function tests are not decreased for 3 weeks.