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      • 스마트폰 블루투스 통신을 사용한 로봇 제어

        김영진;김광우;김가덕;윤호성;김태공;서재현 인제대학교 2012 仁濟論叢 Vol.27 No.1

        SLIS(Software License Integrated Solution) is composed of the 6 parts, Server Agent, Web Server, Client Agent, Client Manager, Service, and Install Shield. For the most part of the project is developed based on MFC platform except for the one, Client Manager, which is built on DDK(Driver Development Kit) and ASP. NET platform. Client Agent program installed on a customer's computer is implemented in 14 different classes. Its main function is able to limit and uninstall the purchased software by using teminateProcess. The purchased softwares expiration dates on customer's computer is being monitored by both Server agent and Client software itself. Client Manager hides the process of Client Agent program which shouldn't be killed by manipulating Process List in Kernel through DDK. To do this, Client Manager is internally implanted and registered in Windows Service to be ran as a part of windows system.

      • 複合 韓藥劑 淸籬滋坎湯의 抗癌效果 및 作用機轉 糾明

        Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.

      • KCI등재

        유기용제에 장기간 폭로된 근로자의 정신의학적 기능과 삶의 질

        김석재,강순아,유지숙,국승희,윤진상,문재동,이형영 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.5

        연구목적: 본 연구는 Y공단의 제조공정에서 저농도의 유기용제(solvent)에 장기간 노출된 근로자의 정신의학적 기능과 삶의 질을 평가하고자 하였다. 방법: 총 142명의 남성근로자 중 유기용제에 폭로된 군(이하 폭로군) 82명과 폭로되지 않는 군(이하 비폭로군) 60명에게 간이정신진단검사(Symptom Checklist-90-R, SCL-90-R), 인지 및 정신운동성검사 (Critical Flicker Fusion Threshold. CFFT; Choice Reaction Time, CRT;Compensatory Tracking Task, CTT;Digit-Symbol Substitution, DDS) 및 한국판 스미스클라인 비챰 삶의 질 척도(Korean version of the SmithKline Beecham 'Quality of Life' Scale, KvSBQOL) 등을 적용하였다. 두 군간의 비교는 평가치의 평균에 대해 t-검증을 하였고 또한 연령과 학력을 공변인으로한 공변량분석(ANCOVA)을 하였다. 결과: SCL-90-R의 9개 증상 차원과 3개 전체 지표 점수는 두 군이 각각 정상범위였다. 그러나 신체화 (Somatization, SOM), 우울(Depression, DEP), 적대감(Hostility, HOS), 공포불안(Phobic anx-iety, PHOB)의 증상차원과 전체심도지수(Global Severity Index, GSI), 표출증상합계(Positive Symptom Total, PST)의 전체 지표는 폭로군이 비폭로군보다 유의하게 높았다. 인지 및 정신운동성 검사와 삶의 질은 두 군간에 유의한 차이는 없었다. 결론: 이상의 결과는 유기용제가 허용치 이하일지라도 장기간 폭로되는 경우에는 정신의학적 문제를 다소 일으킬 수 있음을 시사하였다. 중심단어:유기용제·근로자·정신건강·정신운동성 기능·삶의 질. Objectives: The aim of this study was to evaluate the psychiatric function and quality of life of the chemical workers who had been exposed to long-term, low-level organic solvents in the Y industrial complex. Method: A total of 144 male workers, of whom 82 were in the exposed group and 60 in the unexposed-control group, were evaluated by using Symptom Checklist-90-R(SCL-90-R), series of neuropsychological tests(critical flicker fusion threshold, CFFT) ; choice reaction time, CRT ; compensatory tracking task, CTT) ; digit symbol substitution test, DSS), and the Korean version of the SmithKline Beecham Quality Of Life scale(KvSBQOL). For the statistical analyses, comparisons of the means of the two groups were performed for each variable with two-tailed t-test as well as ANCOVA including age and education as covariates. Results: For the SCL-90-R, the nine symptom scales and the three global indices were clinically within normal range in both groups. However, the scores on the symptom scales of 'somatization','depression','hostility' and 'phobic anxiety', and those on the global indices of 'global severity index' and 'positive symptom total', were significantly higher in the exposed group than in the unexposed group. In terms of the neuropsychological function and the quality of life, there wes no significant difference between the two groups. Conclusion: These findings suggested that the long-term eposure to mixed organic solvents, even at the low level below the permissible exposure limit, might induce some psychiatric problems. KEY WORDS: Organic solvent·Worker·Mental health·Psychomotor function·Quality of life.

      • KCI등재
      • 고정층에서 GAC를 이용한 페놀화합물의 제거

        김경철,조성용,김승재 전남대학교 촉매연구소 2000 觸媒硏究 論文集 Vol.21 No.-

        Adsorption of phenolic compounds from aqueous solution by GAC was studied. Batch tests were carried out to get isotherms. Flow experiments were carried out in a fixed bed. and the operating parameters for the flow reactors are the amount of GAC, concentration of phenolic compounds and liquid flowrate. Adsorption isotherm data are best represented by Freundlich equation and the amounts of equilibrium adsorption by GAC were: o-chlorophenol > p-chlorophenol > phenol. Stirring and aeration in a batch tests increased diffusion coefficient slightly. Breakthrough time deceased as the amount of GAC decreased and liquid flowrate increased. Adsorption data could be predicted by the surface diffusion and pore diffusion models.

      • 프라즈마 噴射層에서의 操作特性

        金炳炫,金勝在,文一植,李基完,堀尾正靭 순천대학교 공업기술연구소 1992 工業技術硏究所論文集 Vol.6 No.-

        A plasma spouted bed(PSB) was operated to find operating parameters and their effects. Experiments were performed with a laboratory scale PSB(bed diameter : 50㎜, orifice diameter : 4㎜, gas : Ar, plasma condition : DC 100V, 40A). The bed surface was observed from the top window and operating parameters were tested by changing gas flow rate and additional resistance after generating plasma. Also plasma jet was tested with particle loading and without within minimum spouting condition. Plasma power and electric potential increase with decreasing additional resistance and with increasing gas flow rate, but particle loading have no effect on plasma jet.

      • SCOPUSKCI등재

        인슐린비의존형 당뇨병 환자에서 Lipoprotein(a)농도와 혈관합병증

        김지연,이태희,박재홍,정민영,양승원,정동진,김명수,김정민,이정훈 대한당뇨병학회 1998 Diabetes and Metabolism Journal Vol.22 No.1

        연구배경: 당뇨병 환자에서 동맥경화증의 발생위험이 정상잉인에 비해 높은 원인의 하나로써 혈액응고와 섬유소용해작용의 이상을 초래하는 Lipoprotein(a) [Lp(a)]가 논의되고 있다. 당뇨병 환자의 동맥경화증과 당뇨병성 합병증 발생위험 증가에 Lp(a)가 어느 정도 관여하는지에 대해서도 아직 확실히 알려져 있지 않다. 저자등은 인슐린비의존형 당뇨병 환자의 혈관합병증(대혈관 및 미세혈관합병증) 발생과 Lp(a)농도와의 관계 및 혈관합병증을 일으키는 다른 위험인자와 Lp(a)농도와의 관련성에 대하여 알아보고자 본 연구를 시행하였다. 방법: 인슐린비의존형 당뇨병 환자 152명(여자:남자=72:80)을 대상으로 공복상태에서 혈중 Lp(a), ApoA1, ApoB, 총 콜레스테롤, 중성지방, 고밀도지단백질-콜레스테롤 등을 측정하였다. 대혈관합병증(허혈성 심질환, 뇌혈관질환, 말초혈관폐쇄성 동맥경화증)의 진단을 위해 증상이 있는 환자들에서 심전도, 관상동맥조영술, 뇌전산호단층촬영, Doppler velocimetry, 말초혈관조영술 등을 시행하였고, 미세혈관합병증은 안저활영, 신경전달속도, BBV(beat to beat variation), VPT(vibration perception threshold), 24시간 요단백량 등을 측정하여 확인하였다. 결과: 허혈성 심질환, 뇌혈관질환등 대혈관질환 및 당뇨병성 망막증 등 미세혈관질환을 갖는 환자에서 Lp(a)농도가 대조군보다 통계적으로 유의하게 증가되어 있었다. Lp(a)농도가 30㎎/dL이상인 군에서 ApoB/ApoA1 및 저밀도지단백질-콜레스테롤이 Lp(a)농도가 30㎎/dL 이하인 군보다 높았으며, 혈관질환을 갖는 군에서 Lp(a)는 높은 ApoB/ApoA1와 저밀도지단백질-콜레스테롤과 통계적으로 의의있는 양의 상관관계를 보였다. 결론: Lp(a)는 인슐린비의존형 당뇨병 환자의 대혈관합병증과 미세혈관합병증(특히 당뇨병성 망막증)에 관련이 있는 것으로 보이며, 특히 저밀도지단백질-콜레스테롤 및 ApoB/ApoA1이 높게 나타난 인슐린비의존형 당뇨병 환자에서 Lp(a)농도 측정이 필요하리라 생각된다.

      • SCIESCOPUSKCI등재
      • 세균성 키토산 가수분해효소의 부분적 특성

        허승만,고영환,하진환,김재하 제주대학교 생명과학연구소 1999 제주생명과학연구 Vol.2 No.-

        chitosan은 D-glucosamine이 β-(1→4) 결합으로 중합된 homopolymer로 chitin을 탈아세틸화(deacetylation)하여 제조된다. chitin은 갑각류의 껍질이나 곤충의 외피, 사상균체의 세포벽을 구성하고 있다. chitin, chitosan 또는 그 분해산물이나 유도체들의 산업적 효율성이 밝혀지면서, 이에 대한 연구가 활발히 이루어지고 있다. 그 중의 한 분야가 효소 분해법을 이용한 chitosan oligomer(chitosanoligosaccharides)의 생산이다. 본 연구에서는 chitosan을 분해하는 미동정 세균의 배양액으로부터 chitosan 가수분해효소(chitosanase)를 분리·정제하여, 주요 특성을 조사하였다. 세균의 무세포 배양액을 한외여과기(NMWL, 1K)로 여과하여 저분자량의 화합물을 제거한 다음 황산암모늄을 가하여 90% 포화시키고, 침전된 단백질을 회수하여 gel permeation chromatography(sephadex G-10과 G-100)로 chitosanase를 정제하였다. 정제전 효소의 비활성은 5.8U/mg 이었으나 정제과정을 통하여 9.7U/mg으로 증대되었다. 정제 전후를 통하여 SDS-PAGE 법에 의한 단백질의 분석과 효소활성 염색으로 한 종류의 chitosanase가 확인되었으며, 그 분자량은 약 30,000dalton 이었고, subunit는 한 종류인 것으로 추정되었다. chitosanase에 의한 기질의 분해산물을 한외여과와 TLC로 분석한 결과, 이 효소는 이량체에서 육량체까지의 chitosanoligosaccharides를 생산하였으며, 단량체를 생산하지 않는 특징이 있었다. 효소반응 최적온도는 40℃이었고, 50℃ 이상에서는 효소의 활성이 급격히 저하되어, 비교적 열안전성이 낮았다. 또한, 이 효소는 pH 5.0∼9.0 범위에서 1시간 방치해도 활성변화가 미미하여, 비교적 광범위한 중성영역에서 안정하였다. Chitosan is a polymer of D-glucosamine linked by β-(1→4) covalent bonds. It is obtained through deacetylation of chitin that occurs mainly in the shells of crustaceans and the exoskeletons of insects. It is also found in fungal cell walls. Having relatively rich natural resources, chitin and their derivatives are widely utilized in industries. Among those are chitosanoligosaccharides that are reported to have several biological functions. The production of chitosanoligosaccharides requires hydrolysis of chitosan by an acid or an enzyme. A chitosanase, the chitosan-depolymerizing enzyme, was purified from unidentified bacterial culture and its characteristics were determined. Cell-free culture of the unidentified bacterium was filtered with ultramembrane(NMWL, 1K) to remove low molecular weight compounds. Ammonium sulfate was added to the filtrate at the level of 90% saturation to induce precipitation of proteins. The precipitated proteins were desalted with sephadex G-10 column and fractionated through sephadex G-100 gel permeation chromatography. Specific activity of the enzyme before purification was 5.8 units/mg and was increased up to 9.7 units/mg through purification procedures. SDS-PAGE analysis of proteins and enzyme activity staining revealed only one kind of chitosanase in the bacterial culture. Its molecular weight was about 30,000 dalton with one kind of subunit. The catalytic unit could highly be a monomeric protein. TLC-analysis of enzymatic hydrolysis products of chitosan showed that the enzyme generated dimeric through hexameric oligomers of D-glucosamine without producing monomeric D-glucosamine. Its optimum temperature for catalytic activity was 40℃ and the catalytic activity dropped rapidly at the temperatures higher than 50℃, which reflected its low heat stability. The enzyme was stable for at least one hour at neutral pH ranges from 5.0∼9.0.

      • 마르크스主義論의 唯物辨證法 硏究

        車在哲,金承鎬 漢陽大學校 人文科學大學 1984 人文論叢 Vol.8 No.-

        The aim of this study is to criticize the materialist dialectic of Marxian philosophy by examining the essence and laws of dialectical materialism. So far, a number of critical studies in examining the materialist dialectic have been developed. Most of them are discussed on the laws of it. This study is consistent with a view point in which the materialist dialectic is products of Marxian methdology. However, based on the assumption that the materialist dialectic is a scientific laws of Marxian philosophy, this examining introduce more critical studies than examined in the prior studies. Judging on the basis of this critical frame, the materialist dialectic is not refer to a philosophy, but to the dogmatic ideologie. Therefore, the materialist dialectic has a dogmatic properties, particutarly in its methodology. A few dogmatic explanations examined in this paper might be presented in a summary from as followings. First, the materialist dialectic is based on Marxian ideologie, because the logics of it admitted dogmatic method. Secondly, the materialist dialectic is a philosophy of non-system, metaphysics. Without considering dogmatic methodology of Marxian philosophy, it is not easy to criticize the laws of materialist dialectic. Finally, it must be point out that the various explanation of ot were contradicted and were seen as the philosophy of poverty.

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