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이상흡 경주대학교 1999 論文集 Vol.12 No.1
Korea's Tourism Policy had focused for the development of tourism industry during the past thirty years, but now it's time to change the tourism policy toward to the national tourism and build new paradigms for tourism education policy toward to the national tourism and build new paradigms for tourism education policy. one of them, the most important thing is the tourism education for the national tourist, because of the incorrected cognition of tourist. especially, in the mass tourism & mass leisure era, the education of tourism & leisure for the people will be impending task and lead to desirable and sound tourism activity. therefore, in this study the necessity of tourism education for the national tourist were suggested, the role & subject of the national tourist education were presented.
Synthesis and Evaluation of Cytotoxicity of Stilbene Analogues
Lee, Sang-Kook,Nam, Kyung-Ae,Hoe, Yeon-Hoi,Min, Hye-Young,Kim, Eun-Young,Ko, Hyojin,Song, Soyoung,Lee, Taeho,Kim, Sanghee The Pharmaceutical Society of Korea 2003 Archives of Pharmacal Research Vol.26 No.4
Resveratrol analogs were newly synthesized and evaluated for cytotoxicity in cultured human lung and colon cancer cells. 3,5,4-Trimethoxy-trans-stilbene and 3,5,2',4'-tetramethoxy-trans-stilbene were found to be more potent rather than resveratrol. 3,4,5-Trimethoxy-4'-bromo-cis-stilbene was the most active among the test compounds.
Atypical Cellular Chorangioma: a rare case and review
( Sanghee Lee ),( Hee Jeong Lee ),( Hae Nam Lee ),( Min Jeong Kim ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Chorangioma of placenta is a benign and common tumor of the placenta composed of blood vessels in 0.5-1% of all pregnancies. Most chorangiomas are small and do not produce any symptom. But a tumour> 4 cm in size is called a giant chorioangioma and associated with maternal, fetal and neonatal complications. The maternal complications include preeclampsia, polyhydramnios, fetal growth restriction, fetal anemia, cardiomegaly and an increasing the risk of preterm labour and placental abruption. Atypical cellular chorangioma is mitotically active tumor with focal necrosis, exhibiting histologic features of a sarcoma. Some authors have suggested that these occasional chorangiomas require evaluation of malignancy. We describe an unusual chorangioma with high cellularity and abundant mitosis that, after careful examination and postpartum follow-up in 30years-old primiparous women (31 gestational weeks with PPROM). Also the careful ultrasonographic examination was also important in prediction palcenta disease.
Lee, Dongsook,Park, Heeju,Kwak, Sanha,Lee, Soomin,Go, Sanghee,Park, Sohyun,Jo, Sukyung,Kim, Kichul,Lee, Seunggwan,Hwang, Doyeong Korean Society of Medical Genetics and Genomics 2016 대한의학유전학회지 Vol.13 No.2
We report the prenatal diagnosis of an unbalanced translocation between chromosome Y and chromosome 15 in a female fetus. Cytogenetic analysis of parental chromosomes revealed that the mother had a normal 46,XX karyotype, whereas the father exhibited a 46,XY,der(15)t(Y;15) karyotype. We performed cytogenetic analysis of the father's family as a result of the father and confirmed the same karyotype in his mother and brother. Fluorescence in situ hybridization and quantitative fluorescent-polymerase chain reaction analysis identified the breakpoint and demonstrated the absence of the SRY gene in female members. Thus, the proband inherited this translocation from the father and grandmother. This makes the prediction of the fetal phenotype possible through assessing the grandmother. Therefore, we suggest that conventional cytogenetic and molecular cytogenetic methods, in combination with family history, provide informative results for prenatal diagnosis and prenatal genetic counseling.
Solid-Phase Library Synthesis of Polyynes Similar to Natural Products
Lee, Seonwoo,Lee, Taeho,Lee, Yun Mi,Kim, Deukjoon,Kim, Sanghee WILEY-VCH Verlag 2007 Angewandte Chemie Vol.46 No.44
<B>Graphic Abstract</B> <P>High in polyunsaturates: The combinatorial synthesis of a 65-membered polyyne library has been achieved by using an iterative acetylene homologation strategy combined with a solid support (see scheme). The library was evaluated against cancer cells to demonstrate its possible utility as a chemical tool to unravel cellular processes or as a platform for drug discovery and design. <img src='wiley_img/14337851-2007-46-44-ANIE200703208-content.gif' alt='wiley_img/14337851-2007-46-44-ANIE200703208-content'> </P>