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Juvvadi Praveen Rao,Seshime Yasuyo,Kitamoto Katsuhiko The Microbiological Society of Korea 2005 The journal of microbiology Vol.43 No.6
Fungal secondary metabolites constitute a wide variety of compounds which either playa vital role in agricultural, pharmaceutical and industrial contexts, or have devastating effects on agriculture, animal and human affairs by virtue of their toxigenicity. Owing to their beneficial and deleterious characteristics, these complex compounds and the genes responsible for their synthesis have been the subjects of extensive investigation by microbiologists and pharmacologists. A majority of the fungal secondary metabolic genes are classified as type I polyketide synthases (PKS) which are often clustered with other secondary metabolism related genes. In this review we discuss on the significance of our recent discovery of chalcone synthase (CHS) genes belonging to the type III PKS superfamily in an industrially important fungus, Aspergillus oryzae. CHS genes are known to playa vital role in the biosynthesis of flavonoids in plants. A comparative genome analyses revealed the unique character of A. oryzae with four CHS-like genes (csyA, csyB, csyC and csyD) amongst other Aspergilli (Aspergillus nidulans and Aspergillus fumigatus) which contained none of the CHS-like genes. Some other fungi such as Neurospora crassa, Fusarium graminearum, Magnaporthe grisea, Podospora anserina and Phanerochaete chrysosporium also contained putative type III PKSs, with a phylogenic distinction from bacteria and plants. The enzymatically active nature of these newly discovered homologues is expected owing to the conservation in the catalytic residues across the different species of plants and fungi, and also by the fact that a majority of these genes (csyA, csyB and csyD) were expressed in A. oryzae. While this finding brings filamentous fungi closer to plants and bacteria which until recently were the only ones considered to possess the type III PKSs, the presence of putative genes encoding other principal enzymes involved in the phenylpropanoid and flavonoid biosynthesis (viz., phenylalanine ammonia-lyase, cinnamic acid hydroxylase and p-coumarate CoA ligase) in the A. oryzae genome undoubtedly prove the extent of its metabolic diversity. Since many of these genes have not been identified earlier, knowledge on their corresponding products or activities remain undeciphered. In future, it is anticipated that these enzymes may be reasonable targets for metabolic engineering in fungi to produce agriculturally and nutritionally important metabolites.
Isolation of a Potent Mosquito Repellent from Vitex negundo L.: An Alternative Source of Rotundial
Praveen K. Amancharla,Patrick S. Muthuraj,Gottumukkala V. Rao,Om V. Singh 한국생약학회 1999 Natural Product Sciences Vol.5 No.2
The chloroform fraction of the aqueous extract of the fresh leaves of Vitex negundo by bioactivity guided isolation yielded a pure compound, rotundial (1) which has shown potent mosquito repellent activity. Using spectral data (LN, IR, ¹H & <sup>13</sup>C NMR and MS) its structure has been elucidated.
Basivi, Praveen Kumar,Pasupuleti, Visweswara Rao,Seella, Ramanaiah,Tukiakula, Madhusudana Reddy,Kalluru, Subramanyam Reddy,Park, Soo-Jin American Chemical Society 2017 Journal of chemical and engineering data Vol.62 No.7
<P>The inverse gas chromatography study on the fluconazole drug surface was performed, and the net retention volumes, polar probes, and VN of n-alkanes are determined at four temperatures over the range 318.15-333.15 K. The net retention values of n-alkanes were used to evaluate the London dispersive surface free energy gamma(L)(S) by three different methods, namely, the Donnet Park, Dorris Gray, and Schultz methods. The gamma(L)(S) values were found to increase from 318.15 to 323.15 K for all three methods and then decrease from 323.15 to 333.15 K. The gamma(L)(S) values were found to be slightly higher in the Schultz method when compared to the results of the Donnet-Park and Dorris-Gray methods. The specific free energy values Delta G(a)(s) and the specific enthalpy Delta H-a(s) values have been calculated using the V-N data of polar probes. The Guttmann Lewis acid base parameters, K-a and K-b, were obtained using Delta H-a(s) values and were found to be 0.217 and 1.518, respectively. The surface character (K-b/K-a) was found to be 7.0. The results revealed that the fluconazole powder surface contains relatively more basic sites than acidic sites and can combine strongly with acidic substrates. The surface energy and acid base data of fluconazole can be used during formulation of the drug and to understand the drug release process.</P>
A Comprehensive Literature Study on Precision Agriculture: Tools and Techniques
Bh., Prashanthi,A.V. Praveen, Krishna,Ch. Mallikarjuna, Rao International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.12
Due to digitization, data has become a tsunami in almost every data-driven business sector. The information wave has been greatly boosted by man-to-machine (M2M) digital data management. An explosion in the use of ICT for farm management has pushed technical solutions into rural areas and benefited farmers and customers alike. This study discusses the benefits and possible pitfalls of using information and communication technology (ICT) in conventional farming. Information technology (IT), the Internet of Things (IoT), and robotics are discussed, along with the roles of Machine learning (ML), Artificial intelligence (AI), and sensors in farming. Drones are also being studied for crop surveillance and yield optimization management. Global and state-of-the-art Internet of Things (IoT) agricultural platforms are emphasized when relevant. This article analyse the most current publications pertaining to precision agriculture using ML and AI techniques. This study further details about current and future developments in AI and identify existing and prospective research concerns in AI for agriculture based on this thorough extensive literature evaluation.
Sridhar Sundaram,Sidharth Harindranath,Praveen Kumar Rao,Nitin Ramani,Aditya Kale,Shraddha Patkar 소화기인터벤션의학회 2021 Gastrointestinal Intervention Vol.10 No.4
Combined biliary and duodenal stent placement has been reported previously in multiple series. Rarely, colonic obstruction may present simultaneously with duodenal and biliary obstruction in advanced pancreaticobiliary cancers. Biliary, duodenal and colonic obstruction managed simultaneously using endoscopic modalities have been reported in only one case report previously. Here we report outcomes of a case of carcinoma of the gall bladder with biliary, gastric outlet and colonic obstruction managed by endoscopic placement of biliary, gastroduodenal and colonic self-expanding metal stents.
Sridhar Sundaram,Sidharth Harindranath,Praveen Kumar Rao,Nitin Ramani,Aditya Kale,Shraddha Patkar 소화기인터벤션의학회 2021 International journal of gastrointestinal interven Vol.10 No.4
Combined biliary and duodenal stent placement has been reported previously in multiple series. Rarely, colonic obstruction may present simultaneously with duodenal and biliary obstruction in advanced pancreaticobiliary cancers. Biliary, duodenal and colonic obstruction managed simultaneously using endoscopic modalities have been reported in only one case report previously. Here we report outcomes of a case of carcinoma of the gall bladder with biliary, gastric outlet and colonic obstruction managed by endoscopic placement of biliary, gastroduodenal and colonic self-expanding metal stents.
권준호(Joonho Kwon),Praveen Rao,문봉기(Bongki Moon),이석호(Sukho Lee) 한국정보과학회 2008 정보과학회논문지 : 데이타베이스 Vol.35 No.4
최근 XML 문서 필터링에 기반한 출판-구독(publish-subscribe) 시스템이 많은 관심을 받고있다. 전형적인 출판-구독 시스템에서, 구독자들은 XPath 언어로 명세된 프로파일로 자신들의 관심을 표현하고, 새로운 내용들은 사용자 프로파일에 대하여 매칭 여부를 판단하여 관심을 가지고 있는 사용자들에게만 배달된다. 구독자의 수와 그들의 프로파일이 증가할수록, 시스템의 확장성이 출판-구독 시스템의 중요한 성공 요소가 된다. 이 논문에서는 FiST 시스템을 확장한 세그먼트 기반의 XML 문서 필터링 시스템인 SFiST 시스템을 제안한다. SFiST 시스템은 XML 문서 필터링에서 중복된 처리를 없애기 위해서 가지형 패턴의 사용자 프로파일에서 세그먼트를 추출하여 해시 기반의 세그먼트 테이블에 저장하고 유지한다. 이 세그먼트는 사용자 프로파일을 터스 시퀀스 형태로 표현하는데 이용되고, 효율적인 필터링을 위한 컴팩트 시퀀스 인덱스에도 사용된다. 실험을 통하여 세그먼트 기반의 SFiST 시스템이 이전의 연구인 FiST 시스템보다 좋은 성능을 가지고 있음을 보였다. In recent years, publish-subscribe (pub-sub) systems based on XML document filtering have received much attention. In a typical pub-sub system, subscribed users specify their interest in profiles expressed in the XPath language, and each new content is matched against the user profiles so that the content is delivered to only the interested subscribers. As the number of subscribed users and their profiles can grow very large, the scalability of the system is critical to the success of pub-sub services. In this paper, we propose a fast and scalable XML filtering system called SFiST which is an extension of the FiST system. Sharable segments are extracted from twig patterns and stored into the hash-based Segment Table in SFiST system. Segments are used to represent user profiles as Terse Sequences and stored in the Compact Segment Index during filtering. Our experimental study shows that SFiST system has better performance than FiST system in terms of filtering time and memory usage.