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Kwak, Jongheon,Han, Sung Hyun,Moon, Hong Chul,Kim, Jin Kon,Koo, Jaseung,Lee, Jeong-Soo,Pryamitsyn, Victor,Ganesan, Venkat American Chemical Society 2015 Macromolecules Vol.48 No.4
<P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/mamobx/2015/mamobx.2015.48.issue-4/ma502192k/production/images/medium/ma-2014-02192k_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ma502192k'>ACS Electronic Supporting Info</A></P>
Case Report : Bovine Leukosis in a slaughtered cow
( Sang Myung Lee ),( Hae Yeun Choi ),( Hak Koo Kwak ),( Chan Woo Jung ),( Seong Tae Han ),( Sun Jun Park ),( Ho Gyu Yoon ),( Rae Hun Jang ) 한국가축위생학회 2007 韓國家畜衛生學會誌 Vol.30 No.4
A slaughtered 3 years old cow was diagnosed as bovine leukosis by postmortem inspection, agar gel immunodifusion (AGID) test, and polymerase chain reaction (PCR). It showed no special clinical signs except emaciation. Grossly, we observed enlargement of mediastinal and pelvic lymph nodes, and tubercle -like mass on pleura and lung surface, and masses on right atrium and ventricle.
a case of severe coronary spasm associated with 5-Fluorouracil Chemotherapy
( Sang Min Kim ),( Cheol Hoon Kwak ),( Bora Lee ),( Seong Beom Kim ),( Jung Ju Sir ),( Wook Hyun Cho ),( Suk Koo Choi ) 대한내과학회 2012 The Korean Journal of Internal Medicine Vol.27 No.3
Cardiotoxicity associated with 5-fluorouracil (FU) is an uncommon, but potentially lethal, condition. The case of an 83-year-old man with colon cancer who developed chest pain during 5-FU infusion is presented. The electrocardiogram (ECG) showed pronounced ST elevation in the lateral leads, and the chest pain was resolved after infusion of nitroglycerin. A coronary angiogram (CAG) revealed that the patient had significant atherosclerosis in the proximal left circumflex artery. Coronary artery spasm with fixed stenosis was considered, and a drug-eluting stent was implanted. After 8 hours, the patient complained of recurring chest pain, paralleled by ST elevation on the ECG. The chest pain subsided after administration of intravenous nitroglycerin followed by sublingual nifedipine. Repeated CAG showed patency of the previous stent. This case supports the vasospastic hypothesis of 5-FU cardiac toxicity, indicating that a calcium channel blocker may be effective in the prevention or treatment of 5-FU cardiotoxicity.
Koo, Gun woo,Chung, Sung Jun,Kwak, Joo Hee,Oh, Chang Kyo,Park, Dong Won,Kwak, Hyeon Jung,Moon, Ji-Yong,Kim, Sang-Heon,Sohn, Jang Won,Yoon, Ho Joo,Shin, Dong Ho,Park, Sung Soo,Oh, Young-Ha,Pyo, Ju Yeon The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.3
Desmoid tumors are rare soft tissue tumors considered to have locally infiltrative features without distant metastasis until now. Although they are most commonly intraabdominal, very few cases have extra-abdominal locations. The origin of intrathoracic desmoid tumors is predominantly the chest wall with occasional involvement of pleura. True intrathoracic primary desmoid tumors with no involvement of the chest wall or pleura are extremely rare. We recently experienced a case of true intrathoracic desmoid tumor presenting as multiple lung nodules at 13 years after resection of a previous intraabdominal desmoid tumor.
KWAK, GYU-SUK,KIM, SUNG-KOO,JUN, HONG-KI 부산대학교 유전공학연구소 2001 분자생물학 연구보 Vol.17 No.-
Bacteriocin J105 is a proteinaceous inhibitory substance produced by Lactococcus lactis subsp. lactis J105 isolated from Kimchi. Bacteriocin J105 was purified to homogeneity by the pH-dependent adsorption-desorption method and reverse-phase HPLC from the culture broth of Latococcus lactis subsp. lactis J105. Purification of bacteriocin J105 resulted in a 1.47-fold increase in the specific activity and the recovery was 1.5%. Its molecular mass measured by the electrophoretic pattern in the sodium dodecyl sulfate polyacrylamide gel was about 3.4kDa. It was stable at 121℃ for 15min at pH between 2 and 4. However, at pH above 5, bacteriocin was rapidly inactivated. Twenty-one residues from the N-terminal portion of bacteriocin J105 showed significant homology with known nisin A from lactic acid bacteria.
Kwak, Yunyoung,Kim, Sang-Jun,Rhee, In-Koo,Shin, Jae-Ho 한국응용생명화학회 2012 Applied Biological Chemistry (Appl Biol Chem) Vol.55 No.6
Quantitative real-time PCR (qPCR) method was applied to quantify the functional gene encoding organophosphorus hydrolase for assessing the degradation efficacy by bacterial strains on an organophosphorus compound in in situ soil. The specific primers targeting the organophosphorus hydrolase were designed and tested on reference bacterial strains and in DNA samples extracted from in situ soil samples contaminated by an organophosphorus compound. The established qPCR assay is a practical method for the analysis of in situ soil samples undergoing bioremediation of organophosphorus compounds.
Kwak, Cheol-Hoon,Sir, Jung-Ju,Lee, Bo-ra,Kim, Sang-min,Kim, Seong-Beom,Lee, Hong-Ki,Cho, Wook-Hyun,Choi, Suk-Koo 인제대학교 2008 仁濟醫學 Vol.29 No.-
상부 심부혈전증은 매우 드문 질환이며 본 증례는 상부 심부혈전증으로 발견 된 재발된 위암이다. 70세 여자 환자가 2 주전부터 발생한 좌측 상완 부종을 주소로 내원하였다. 환자는 8년 전 진행성 위암 (3기) 으로 진단받고 아전위절제술 및 수술 후 보조 항암 요법을 시행 받았다. 이후 특별한 증상 없이 외래로 추적 관찰 중, 최근 좌측 상완 부종 호소하여 시행한 흉부 컴퓨터 단층 촬영 상 좌측 액와-쇄골 하 정맥 내 혈전이 발견되어 입원하였다. 좌측 상완의 정맥 조영술에서 좌측 액와-쇄골 하 정맥 내 충만 결손이 관찰되었다. 컴퓨터 단층 촬영 상복강내에 다량의 복수와 결절이 관찰되었으며 세포 조직 검사에서 위암으로 확진되었다. 환자는 항응고 요법 시행 후 좌완의 부종은 호전되었고 항암 요법 시행 후 퇴원하여 외래에서 추적 관찰 중이다.
Kwak, Young-Woo,Lee, Kyung-Koo,Cha, Seung-Hun,Lee, Sang-Koo,Lee, In-Sook,Park, Yong-Tae,Lee, Jae-Keun,Yoh, Soo-Dong,Kim, Woo-Sik Korean Chemical Society 2003 Bulletin of the Korean Chemical Society Vol.24 No.4
The reactions of 2,5-bis(ethynyldimethylsilyl)thiophene (1) with aromatic dihalides(1,4-dibromobenzene, 4,4'- dibromobiphenyl, 9,10-dibromoanthracene, 2,5-dibromopyridine, 2,5-dibromothiophene, and 2,6-diiodo-4- nitroaniline) were carried out in the presence of a $[(PPh_3)_2PdCl_2]$-CuI catalyst in refluxing triethylamine to give poly{[2,5-bis(ethynylenedimethylsilylene)thienylene](arylene)} (2-7) with molecular weights of 2200-7400. The oligomers reveal characteristic absorption in the UV/visible region. The thermal behavior of 2-7 was examined by thermogravimetric analysis in an argon atmosphere.
( Sung Hwa Lyu ),( Yoon Ho Kwak ),( Young Kyun Lee ),( Yong Chan Ha ),( Kyung Hoi Koo ) 대한고관절학회 2014 Hip and Pelvis Vol.26 No.2
Purpose: The purpose of this study is to determine structural bony abnormalities predisposing for femoroacetabular impingement by comparison of patients with and without mechanical symptoms. Materials and Methods: We conducted this comparative study on 151 patients (151 hips; mean age 44.8 years; range 16-73 years) with mechanical symptoms with results of multi-detector computed tomography (MDCT) arthrography (the symptomatic group). Each patient was matched with a control who underwent MDCT due to ureter stone (the asymptomatic group) in terms of age, gender, site (right or left), and time at diagnosis. Acetabular evaluations, which included cranial and central anteversion and anterior and lateral center edge angles and femoral measurements, were performed. In addition, we evaluated the prevalence and characteristics of structural bone abnormalities between the two groups. Results: The prevalence for patients who had at least one structural bony abnormality in the symptomatic and asymptomatic groups was 80.1% (121/151) and 54.3% (82/151), respectively (odds ratio: 3.39, 95% confidence interval: 2.30-5.66; P<0.001). The most common osseous abnormality was the isolated Pincer type in both groups: 89 (73.6%) of 121 hips with an osseous abnormality in the symptomatic group and 57 (69.5%) of 82 hips with an osseous abnormality in the asymptomatic group. By analysis of CT arthrography in symptomatic patients, a labral tear was found in 107 hips (70.9%), and 86 (80%) of these hips had a structural bony abnormality. Conclusion: A significantly greater prevalence rate of structural bony abnormality was observed for the symptomatic group than for the asymptomatic group. These findings are helpful for development of appropriate treatment plans.