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Kim, Injung,Park, Jongkeun,Kim, Jeong-Ki,Kim, Bong-Kyu,Lee, Hwayoung,Choi, Keonwoo,Yoon, Jong-Bok,Yoon, Sungjoo Kim Springer-Verlag 2014 Genes & Genomics Vol.36 No.3
T-cadherin is frequently down regulated in various cancers, however, the underlying mechanisms responsible have yet to be elucidated. A genome wide association study of a cohort of Korean adults revealed that the T-cadherin rs3865188 single nucleotide polymorphism (SNP) was associated with serum Adiponectin levels and that its genotypic variants were correlated with risk for colorectal cancer (CRC). To test the function of rs12444338, a SNP tightly linked to the rs3865188 SNP, in T-cadherin transcriptional regulation in colorectal cancer, its effect on transcriptional activity and the capacity of binding activity attributable to allelic variation of the rs12444338 SNP was investigated. An electrophoretic-mobility-shift assay (EMSA) revealed a specific nucleoprotein complex unique to the T allele probe, which displayed lower promoter activity when compared to the G allele. Based on the results of the EMSA using mutant probes, the consensus sequence of the putative transcription factor binding site was determined. Additionally, candidates for putative binding factors to the T allele were also identified. Collectively, the study data suggested that the rs12444338 SNP was involved in transcriptional regulation of T-cadherin gene (CDH13) and that the differential binding of transcription factors at the rs12444338 SNP resulted in altered gene expression. These results elucidate, at least in part, the regulation of T-cadherin expression in CRC and provide further information regarding the effect of nucleotide variation in its promoter region.
Injung Kim,Kyeongjin Kim,Sungjin Lee,Kwang W. Kim 한국도로학회 2018 한국도로학회 학술대회 발표논문 초록집 Vol.2018 No.05
There are some places such as bridges in the heavily industrialized area where the pavement should have a strong resistance against heavy axle loading and waterproof function. In those places, many polymer-modified asphalt (PMA) pavements were applied to protect premature cracking, severe rutting and water intrusion without success. Therefore, a much tougher pavement material with waterproofing function was developed for those places. This study evaluated important properties of the special type asphalt mixture which is highly condensed to be almost void-free condition. A high-quality PMA binder with PG82-34 grade was used for preparing the mixture and the optimum binder content was determined to allow near 0% air void in the mix design. The deformation strength(SD) by Kim Test and rut depth by wheel tracking test were measured at 60℃ as high temperature properties. The flexural strength and fracture toughness was measured at -10℃ as low temperature property. The void-free AC showed the higher performance in all four properties than any other asphalt concretes which were prepared for comparison. Therefore, it was shown that the normal concern about limiting air voids within 3-5% was just an apprehension. The void-free AC can be applied for heavy duty pavement on the bridge where the water-proofing function and higher rutting and cracking resistance are required.
김인중(Injung Kim),나기현(Kihyun Na),양소희(Sohee Yang),장재민(Jaemin Jang),김윤종(Yunjong Kim),신원영(Wonyoung Shin),김덕중(Deokjung Kim) Korean Institute of Information Scientists and Eng 2017 정보과학회논문지 Vol.44 No.8
T-commerce is technology-fusion service on which the user can purchase using data broadcasting technology based on bi-directional digital TVs. To achieve the best revenue under a limited environment in regard to the channel number and the variety of sales goods, organizing broadcast programs to maximize the expected sales considering the selling power of each product at each time slot. For this, this paper proposes a method to predict the sales of goods when it is assigned to each time slot. The proposed method predicts the sales of product at a time slot given the week-in-year and weather of the target day. Additionally, it combines a statistical predict model applying SVD (Singular Value Decomposition) to mitigate the sparsity problem caused by the bias in sales record. In experiments on the sales data of W-shopping, a T-commerce company, the proposed method showed NMAE (Normalized Mean Absolute Error) of 0.12 between the prediction and the actual sales, which confirms the effectiveness of the proposed method. The proposed method is practically applied to the T-commerce system of W-shopping and used for broadcasting organization.
Kim, Jihee,Choi, Seungse,An, Injung,Lee, Seunghyuk,Lee, Eun Ju,You, Young-Han,Kim, Baek-Jun,Han, Donguk,Park, Sangkyu,Joo, Sungbae National Institute of Ecology 2021 국립생태원회보(PNIE) Vol.2 No.3
Hulunbuir steppe, one of the four largest steppes in China, has experienced rapidly progressing desertification partly due to overgrazing by livestock. The objective of this study was to investigate the effectiveness of various vegetation recovery methods, including the selection of unpalatable plants less affected by grazing livestock. To determine livestock grazing preferences at Hulunbuir restoration sites, we used DNA barcoding methods to analyze fecal materials of horses and cattle grazing on four restored plants: two trees (Pinus sylvestris L. var. mongolica and Populus canadensis) and two shrubs (Caragana microphylla and Corethrodendron fruticosum). Neither of the two tree species were detected in livestock feces, whereas both shrub species were detected at lo w frequencies. There were no significant differences in compositions of species consumed by horses and cattle except that Asteraceae species were more often consumed by cattle. Our results showed that the four plants used for restoration may be classified as unpalatable or less palatable species in the Hulunbuir restoration area. Our results may help inform restoration strategies implemented in restoration areas, especially regarding negative effects of livestock grazing during the initial stage of restoration in Hulunbuir.
클라우드 스토리지를 이용한 개인 컴퓨팅 환경의 이동성 지원 서비스
김인정(Injung Kim),우종정(Jongjung Woo) 한국정보기술학회 2014 한국정보기술학회논문지 Vol.12 No.8
People always want to have their own computing environments by carrying on the laptop or the portable storage for their workspace anywhere. But it is difficult to always carry the laptop or run their own application at any place. Thus several technologies to support the mobility of personal workspace on the portable storage like a USB hard drive have been studied. Nevertheless, they have still some problems with its limited storage space and its data loss and damage. Therefore, this paper propose to move personal computing environment on the cloud storage with an extracting technique of Windows-based setup files and registries and an IRP forwarding technique. It also presents the process to support the mobility of personal workspace by using KT uCloud Storage which is fit for the domestic users.