Preparation and Polymerization of Alkenylsilanes

김정균,최순규,박은미,정인경,Kim, Chung Kyun,Choi, Soon Kyu,Park, Eun Mi,Jung, In Kyung Korean Chemical Society 1997 대한화학회지 Vol.41 No.2

The silyltriflates$(Ph_{3-n}SiH(OTf)_n)$have been produced by the reaction of triphenylsilane and triflic acid$(CF_3SO_3H)$at low temperature. These highly reactive compounds are a valuable reagent for the synthesis of numerous new functional substituted silane derivatives. The reaction of silyltriflates with alkenyl- and alkynylmagnesium bromide as well as organolithium compounds gave new silanes$Ph_2SiHR(R=\;C(CPh,\;CH=CH_2,\;CH_2CH=CH_2,\; (CH_2)_2CH=CH_2,\;(CH_2)_3CH=CH_2)$in high yields. The hydrosilation of prepared alkenyl- and alkynylsilanesPh_2SiHR$in the presence of a platinum catalyst(Pt/C) at high temperature$(200{\circ}C)$gave carbosilane polymers$((Ph_2SiCH=CPh)_n$and$(Ph_2Si(CH_2)m)n;\;m=2∼4, n{\ge}10)$along with five- and six-membered silaalkane ring compounds derived from intramolecular hydrosilation reactions. All of the prepared compounds are confirmed by NMR, UV, IR and mass spectroscopy as well as elemental analysis. 실릴트리플레이트$(Ph_{3-n}SiH(OTf)_n))$는 낮은 온도에서 트리펜일실란과 트리플산$(CF_3SO_3H)$의 반응에 의해 형성되며 이러한 화합물은 새로운 기능성 실란 유도체의 제조에 이용되고 있다. 실릴트리플레이트와 알캔일-, 알킨일마그네슘 브롬아이드 그리고 유기리티움 화합물과의 반응에 의해 새로운 실란 화합물 Ph_2SiHR(R=C{\equiv}(CPh,\;CH=CH_2,\;CH_2CH=CH_2,\;(CH_2)_2CH=CH_2,\;(CH_2)_3CH=CH_2)$을 높은 수율로 얻었다. 합성된 알켄일-, 알킨일실란은 백금촉매 하에서 카보실란 고분자$((Ph_2Si(CH_2)m)n;\;m=2∼4,\;n\le10)$5~6환고리 화합물을 형성하였다. 모든 생성물들은 NMR, UV, IR, 질량분석, 그리고 원소분석법에 의해 확인되었다.

Carbosilane 고분자상의 나무가지꼴 실란거대분자 형성: Silane Arborols $(V)^1$

김정균,박은미,정인경,Kim, Chung Kyun,Park, Eun Mi,Jung, In Kyung 대한화학회 1996 대한화학회지 Vol.40 No.5

The selective cleavage of phenylsilane by triflic acid gives silyltriflates. The removal of phenyl groups in $Ph_3SiH$ and carbosilane polymer $(Ph_2SiCH_2CH_2CH_2)n$ with one to two equiv of triflic acid leads to formation of mono- and disubstituted silyltriflate ester bonds. Reaction with allylmagnesium bromide produces corresponding derivatives with good yields. An organosilane dendrimer with allylated carbosilane polymer has been synthesized up to G3 using repetitive allylation hydrosilylation cycles. 트리플산에 의한 phenylsilane 의 선태적 분해반응에서는 silyltriflate ester 결합을 형성하였다. 1 혹은 2당량배의 트리플산에 의한 $Ph_3SiH$과 carbosilane 고분자$(Ph_2SiCH_2CH_2CH_2)n$의 Ph기 치환반응에서는 1 혹은 2치환 silyltriflate ester 결합을 형성하였으며 이들과 allylmagnesium bromide와의 반응에 의해 이에 상응되는 화합물을 높은 수율로 얻었다. Carbosilane 고분자의 나무가지꼴 실란거대분자를 allylation 과 hydrosilation법에 의해 제3세대(G3)까지 합성하였다.

開咬症을 隨伴한 下顎前突症 外科的 治驗例

Jung Ho Yoon(尹仲鎬),Hyung Sik Park(朴亨植),Young Soo Kim(金榮洙),Eui Wung Lee(李義雄),Hyoung Gon Kim(金亨坤),Ji Ho Kim(金知浩),Jyung Kyun Kim(金正均) 대한구강악안면외과학회 1981 대한구강악안면외과학회지 Vol.7 No.1

This is a case report of mandibular prognathism with anterior open bite by intraoral Obwegeser-Dalpont s Sagittal split osteotomies in the rami with genioplasty. We suspected this facio-dental deformity to be caused by developmental hypertrophy of mandible, proper selection of operative method was determined by depending upon preoperative work-ups such as radiographic survey, study model analysis and model surgery, cephalometric analysis and gross evaluation of facio-dental deformities. After surgical correction, Improvement of esthetic and functional problem has been obtained and maintained satisfactorily without any complications.

실시간 In-situ IR을 사용한 벌크상 Poly(oxytetramethylene) Glycol과 Isophorone Diisocyanate의 반응속도론 연구

김정균 ( Jung Kyun Kim ),조항규 ( Hang Kyu Cho ),노시태 ( Si Tae Noh ),강신춘 ( Shin Choon Kang ) 한국공업화학회 2002 공업화학 Vol.13 No.8

실시간 정량적 분석이 가능한 In-situ IR을 사용하여 poly(oxytetramethylene) glycol (PTMG)과 isophoron diisocyanate(IPDI) 간의 반응 속도론적 연구를 수행하였다. 반응 속도는 일련의 IR 스펙트럼에서 NCO 신축진동흡수(2265 cm^1) 및 C=O 신축진동흡수(1725 cm^1)대의 흡광도 변화를 모니터링하여 얻었다. 반응은 수산기와 이소시아네이트기의 농도에 대하여 각각 1차이고, 전체적으로 2차인 반응 속도법칙에 따랐다. PTMG와 IPDI의 벌크 중합에서 [NCOJ/[OH]=1.0일 때 반응 속도 상수로부터 구한 활성화 파라미터는 E_a = 61.07 kJ/mol, △H^* = 58.18 kJ/mol 및 △S^# = -95.98 J/molㆍK 이었다. Using quantitative real-time In-situ infrared (In-situ IR) spectroscopy, kinetic study of a reaction between isophoron diisocyanate (IPDI) and poly(oxytetramethylene) glycol (PTMG) was carried out. The reaction rate was obtained from monitoring the change of NCO (2265 cm^-1) and C=O (1725 cm^-1) stretching band in series IR spectra. The reaction was in accordance with the first-order reaction for each concentration of hydroxyl groups and isocyanate group, respectively, however, the overall reaction conformed to the second-order law. In the bulk polymerization between PTMG and IPDI, with ratio of [NCOJ/[OH] equal to 1.0 at various temperatures, the activation parameters obtained from the evaluation of kinetic data were △H^* = 58.18 kJ/mol, △S^# = -95.98 J/molㆍK and E_a = 61.07 kJ/mol.

이종이식된 인체종양에서 KR - 30035 가 Tc - 99m MIBI 체내 분포에 미치는 영향으로 평가한 다약제내성 역전가능성

김정균(Jung Kyun Kim),이재태(Jae Tae Lee),이병호(Byung Ho Lee),최상운(Sang Woon Choi),유성은(Sung Eun Yoo),이상우(Sang Woo Lee),천경아(Kyung Ah Chun),안병철(Byeong Cheol Ahn),박재용(Jae Young Park),서장수(Jang Soo Suh),이규보(Kyu Bo 대한핵의학회 2001 핵의학 분자영상 Vol.35 No.3

N/A Purpose: KR-30035 (KR), a new MDR reversing agent, has been found to produce a similar degree of increased Tc-99m MIBI uptake in cultured tumor cells over-expressing mdr1 mRNA compared to verapamil (VP), with less cardiovascular effects. We assessed the MDR-reversing ability of KR in vivo, and effects of various doses of KR on MIBI uptake in nude mice bearing P-glycoprotein (P-gp) positive (+) and P-gp negative (-) human tumor xenografts. Methods: P-gp (+) HCT15/CL02 colorectal and P-gp (-) A549 non-small cell cancer cells were inoculated in each flank of 120 nude mice (20 mice x 6 groups). Group 1 (Grl) mice received 10mg/kg KR i.p. 3 times (x3) Gr2, 10mg/kg VP i.p. x3: Gr3, 10mg/kg KR i.p, x2 + 25mg/kg KR i.p. x1 Gr4, 10mg/kg KR i.p. x2 + 50mg/kg i.p. x1' Gr5, 10mg/kg KR i.p. x2 + 25mg/kg KR i.v. x1, GrC, controls. The mice were then injected with Tc-99m MIBI and sacrificed after 10 min, 30 min, 90 min and 240 min. Tumor uptake of MIBI (TU) in each group was compared. Results: TU in P-gp (+) and (-) tumors were both higher in Grl than Gr2. Washout rate between the 10 min and 4 hours was lower in Gr5 of P-gp (+) cell(0.93) than the control. Percentage increases in TU were higher in P-gp (+) than P-gp (-) tumors with all KR doses. Pgp (+) TU were highest at 10 min (173% of GrC) and persisted up to 240 min (144%) in Gr3. Larger doses of KR resulted in a lesser degree of increase in P-gp (+) TU at 10 min (130% in Gr4 and 117% in Gr5) and 30 min (178% 129%), but TU increased by time up to 240 min (177% 196%). Heart and lung uptakes were markedly increased in Gr4 and Gr5 at 10 and 30 min, likely due to cardiovascular effects. No mice died. Conclusion: These data further suggest that KR that has signiticantly lower cardiovascular toxicity than verapamil can be used as an active inhibitor of MDR. Even a relatively low dose of KR significantly increased Tc-99m MIBI uptake in P-gp (+) tumors in vivo. (Korean J Nucl Med 200135:168-184)

유동형 미세 열유속 센서의 설계

김정균(Jung-Kyun Kim),조성천(Sung-Cheon Cho),이선규(Sun-Kyu Lee) Korean Society for Precision Engineering 2009 한국정밀공학회지 Vol.26 No.11

A suspended membrane micro fluidic heat flux sensor that is able to measure the heat flow rate was designed and fabricated by a complementary-metal-oxide-semiconductor-compatible process. The combination of a thirty-junction gold and nickel thermoelectric sensor with an ultralow noise preamplifier, low pass filter, and lock-in amp has enabled the resolution of 50 ㎻ power and provides the sensitivity of 11.4 ㎷/㎼. The heater modulation method was used to eliminate low frequency noises from sensor output. It is measured with various heat flux fluid of DI-water to test as micro fluidic application. In order to estimate the heat generation of samples from the output measurement of a micro fluidic heat-flux sensor, a methodology for modeling and simulating electro-thermal behavior in the micro fluidic heat-flux sensor with integrated electronic circuit is presented and validated. The electro-thermal model was constructed by using system dynamics, particularly the bond graph. The electro-thermal system model in which the thermal and the electrical domain are coupled expresses the heat generation of samples converts thermal input to electrical output. The proposed electro-thermal system model shows good agreement with measured output voltage response in transient state and steady-state.

DEA/AHP 기법을 이용한 A보험회사의 IT서비스 유지보수 효율성 분석 연구

김정균(Jung Kyun Kim),김우제(Woo Je Kim) 동국대학교 경영연구원 2020 경영과 사례연구 Vol.42 No.1

최근 기업들은 IT서비스를 중심으로 업무를 진행하고 있으며, 이를 기반으로 고객에게 서비스를 제공하고 있다. I이에 따라 기업대세는 많은 비용 및 인력을 투입하여 IT서비스에 대한 유지보수를 하고 있다. 기업들은 IT 서비스 유지보수 효율성을 파악하려고 하나, 이를 분석할 수 있는 도구 및 모형들이 없는 실정이다. 본 논문에서는 DEA와 AHP 기법을 활용하여 보험회사의 유지보수 효율성을 분석하는 모형을 개발하였으며, 보험회사의 IT서비스에 대해 사례 검증을 실시하였다. DEA(Data Envelopment Analysis)는 투입요소와 산출요소를 분석하여 효율성을 측정하는 기법이다. 본 연구에서는 DEA 모델의 투입요소로 유지보수 규모화 비용, 유지보수 복잡도를 사용하였으며, 산출요소로 유지보수 만족도를 사용하였다. 본 연구는 IT서비스 유지보수를 활용하는 기업에서 활용될 수 있을 것으로 기대되며, IT서비스 유지보수 효율성 분석에 대한 새로운 연구모델로 활용될 수 있을 것으로 기대한다. Many companies are going to work through a lot of IT services to provide customer service. IT services are becoming increasingly complex and diverse, so they are maintained with a lot of money and manpower. Each company wants to know how much efficiency it has for maintenance, but there is no way to know where the tools for analyzing these things are. To improve ongoing work and customer service, each company will need to know how much maintenance efficiency it experiences. In this study, we analyze the efficiency of maintenance for IT service in A insurance company using DEA/AHP method. We develop a model to measure the efficiency of IT service. In the DEA model, the scaled cost for maintenance of IT service with function point and maintenance complexity of IT service are used as the input factors, and the degree of satisfaction for maintenance of IT service is used as the output factor. For the maintenance complexity and the degree of satisfaction for maintenance, the detailed elements are derived, and these detailed elements are weighted by the AHP technique. The company can evaluate the efficiency of IT service maintenance with the developed model.

拔齒創의 治癒에 關한 實驗的 硏究

金正均(Jung Kyun Kim) 대한치과의사협회 1972 대한치과의사협회지 Vol.10 No.5

전자부품의 방열방향에 따른 접촉열전도 특성

김정균(Jung-Kyun Kim),Wataru Nakayama,이선규(Sun-Kyu Lee) Korean Society for Precision Engineering 2010 한국정밀공학회지 Vol.27 No.1

The increasing of power and processing speed and miniaturization of central processor unit (CPU) used in electronics equipment requires better performing thermal management systems. A typical thermal management package consists of thermal interfaces, heat dissipaters, and external cooling systems. There have been a number of experimental techniques and procedures for estimating thermal conductivity of thin, compressible thermal interface material (TIM). The TIM performance is affected by many factors and thus TIM should be evaluated under specified application conditions. In compact packaging of electronic equipment the chip is interfaced with a thin heat spreader. As the package is made thinner, the coupling between heat flow through TIM and that in the heat spreader becomes stronger. Thus, a TIM characterization system for considering the heat spreader effect is proposed and demonstrated in detail in this paper. The TIM test apparatus developed based on ASTM D-5470 standard for thermal interface resistance measurement of high performance TIM, including the precise measurement of changes in in-situ materials thickness. Thermal impedances are measured and compared for different directions of heat dissipation. The measurement of the TIM under the practical conditions can thus be used as the thermal criteria for the TIM selection.

NPC와 B-Bridge 컨버터의 부스트 벡터와 커패시터전압의 해석

김정균(Jung-Kyun Kim),김태진(Tae-Jin Kim),강대욱(Dae-Wook Kang),현동석(Dong-Seok Hyun) 전력전자학회 2002 전력전자학술대회 논문집 Vol.- No.-

This paper discover another boost vectors In high modulation index In steady states, modulation index of converter operation is normally 0.7~08 [p u] Even though zero vectors are not unposed, DC-Link voltage is constant because 3-level boost convert has another boost vectors<br/> and this paper proposes the analysis and the comparison for NPC and H-Bridge converter It proposed the calculation method for the voltage ripple and charging current of each capacitor and deals with voltage balance problems of each link capacitor they are associated with the switching state, the position of reference voltage vector<br/> simulation and analysis are used In order to prove validity of the proposed methods