15주간의 신체 활동 증진 프로그램이 여자 대학생의 신체 조성 및 혈중 지질 농도에 미치는 영향

장지훈,성기홍,김남익,조국래,이동수 한국유산소운동과학회 2002 대한스포츠융합학회지 (jcses) Vol.6 No.1

The purpose of this study was to develop the lecture model as liberal arts which have the positive effects to promote physical activity and to decrease obesity-dated variables. Subjects in this study were women university students, and they were divided into two groups to voluntary applying; one was tennis group (n=10), the other table tennis group (n=10). Physical activity promotion program in this study was practiced one time a week, 130 min. one time with the intensity under 83% predicted HR max for 15 weeks. Anthropometrics, body fat(%), blood lipid profile were measured before and after attending the program, respectively. After 15-week-physical activity promotion program, body weight, BMI, WHR, body fat(%), total cholesterol concentration, triacylglyceride concentration were decreased significantly in both groups (p<.5). Resting heart rate was decreased significantly only in tennis group (p<.5). No significance was shown in systolic and diastolic blood pressure to both groups.

Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예

백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy

異功散의 免疫增强效果에 관한 實驗的 硏究

안규석,이경태,장성구,정지창,노영수 世明대학교 한의학연구소 1999 韓醫學硏究所 論文集 Vol.2 No.-

This experimental study was carried out to evaluate the immunomodulatory effects of Ekong-san. To evaluate the immunomodulatory effects of Ekong-san, delayed type hypersensitivity, hemagglutinin and hemolysin titers for hymoral immune response, rosette forming cells for cell-mediated immune response, natural killer cell activity, proliferation of lymphocyte, productivity of Interleukin-2, and carbon clearance were measured with methotrexate treated mice. The results were summarized as follows; 1.The influence of the treatment on hemagglutinin and hemolysin titers, rosette forming cells, the proliferation of lymphocyte, and productivity of Interleukin-2 was dose-dependent and the results showed a significant difference when compared to control group. This implies that the humoral immune response was activated. 2.The natural killer cell activity was significantly increased in both sample groups as compared to the control group when the effector cell:target cell ratios were 100:1 and 0:1. However when the ratio was 10:1, there was no significant difference with the control group. 3.Carbon clearance, the proliferration effect of phagocytes was significantly increased sample group as compared to the control group. According to the results, Ekong-san has the immuno-activity. We could suggest that Ekong-san is able to be applied to the anti-cancer treatment and prevention.

The Morphometric Analysis of the Extraforamen in the Lumbosacral Spine: Magnetic Resonance Imaging and Computed Tomography Study

Jang, Jee-Soo,Lee, Sang-Ho The Korean Neurosurgical Society 2005 Journal of Korean neurosurgical society Vol.37 No.5

Objective: The goal of this study is to establish the anatomical criteria of the normal and stenotic lumbosacral extraforaminal tunnel, and also to determine the effect of the pathologic intervertebral disc on the size of extraforaminal tunnel in the lumbosacral spine. Methods: MRI and CT scans were reviewed and classified into two groups: (1) 40 patients with normal discs at L5- S1 (Group 1) and (2) 43 patients that had undergone successful decompression surgery for extraforaminal entrapment at the lumbosacral region(Group 2). In these two groups, the following parameters were compared are compared: the distance between the disc margin and the ala (lumbosacral tunnel) on the axial MRI, and the posterior disc height at L5-S1 on the mid-sagittal MRI. Results: In the group 1, the mean distance of the lumbosacral tunnel on the axial MRI was $10.1{\pm}2.2mm$. The mean posterior disc height at L5-S1 was $7.4{\pm}1.7mm$ on the mid-sagittal MRI. In the group 2, the mean distance between the disc margin and the ala (costal process) was $1.6{\pm}1.3mm$ on the axial MRI. The average posterior disc height was $4.4{\pm}1.5mm$ on the mid-sagittal MRI. The posterior disc height and the size of the lumbosacral tunnel between the two groups were statistically different on the paired t-test (p<0.0001). However, the posterior disc height was not positively correlated with the size of the extraforaminal tunnel for group 2 (p=0.909). Conclusion: The extraforaminal stenosis was correlated to pathologic disc. However, the posterior disc height was not correlated to the size of the of the extraforaminal tunnel.

The Triple Entrapment Syndrome of the 5th Lumbar Spinal Nerve

Jang, Jee-Soo,Lee, Sang-Ho The Korean Neurosurgical Society 2005 Journal of Korean neurosurgical society Vol.37 No.4

Objective: The 5th lumbar spinal nerve can be entrapped in the intraspinal zone, foraminal zone, and the extraforaminal zone simultaneously. The failure to recognize that the nerve root can be compressed in such manners may be the reason of a number of failures of surgical decompression. Here we describe a microsurgical method for the decompression of the triple entrapment of the L5 spinal nerve in 21 patients. Methods: Clinical manifestations and surgical results of twenty-one patients treated surgically under the diagnosis of the triple entrapment of the L5 spinal nerve were reviewed retrospectively. All patients were treated by the posterior midline approach for the intraspinal entrapment and by the paraspinal approach for the foraminal and the extraforaminal entrapment. Results: Pain relief was obtained in all patients immediately after surgery. The mean follow-up period after the surgery was 13 months, ranged from 6 to 24 months. The mean Numeric Rating Scale (pain score) improved from 8.9 before the surgery to 1.4 (P<0.0001). The mean ODI scores improved from 76.2 before the surgery to 13.1 (P<0.0001). Nineteen patients were satisfied with their result at the last follow-up examination. Neither complications related to the surgery, nor the spinal instability was detected. Conclusion: The triple entrapment of the 5th lumbar spinal nerve is an important pathologic entity to identify for the treatment of L5 radiculopathy. Combined medial and lateral approaches are safe, minimally invasive and it provide the complete decompression of triple entrapment of the L5 spinal nerve without causing secondary instability like after complete facetectomy.

Pedicle screw placement in the thoracic spine using a guide device A cadaveric study

Jee Soo Jang,Won Bok Lee,Hansen A Yuan 대한체질인류학회 2000 대한체질인류학회 학술대회 연제 초록 Vol.43 No.-

Pharmacokinetic properties of trifolirhizin, (–)-maackiain, (–)-sophoranone and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran after intravenous and oral administration of<i>Sophora tonkinensis</i>extract in rats

Jang, Soo Min,Bae, Soo Hyeon,Choi, Woong-Kee,Park, Jung Bae,Kim, Doyun,Min, Jee Sun,Yoo, Hunseung,Kang, Minseok,Ryu, Keun Ho,Bae, Soo Kyung Informa UK (Informa Healthcare) 2015 Xenobiotica Vol.45 No.12

사회복지실천론 교과목 지침서 개선방안 연구: 델파이방법을 통한 고찰

장수미(Jang Soo Mi),최지선(Choi Ji-Sun),이지수(Lee Jee Soo) 한국사회복지교육협의회 2019 한국사회복지교육 Vol.45 No.-

한국 사회복지실천교육의 문제점은 오랫동안 다양한 측면에서 제기되어 왔는데, 실천학문으로서 사회복지학이 현장을 반영하고 있지 못하다는 비판이 대표적이다. 이에 본 연구는 실천현장에서 필요한 사회복지사의 역량에 기초한 “역량기반 교육”을 위하여 사회복지실천론 교과목에서 다루어야 할 사회복지사의 역량, 교육목표와 내용을 델파이방법을 통해 도출하고자 하였다. 조사에 응한 델파이 패널은 전국 대학에서 사회복지실천론을 강의하는 전임교수 42명이었으며, 1~3차에 걸쳐 주관식, 객관식 질문에 의한 조사가 이루어졌다. 연구결과에 따르면 ‘통합적 사회복지실천에 대한 이해와 적용역량’ 등 10대 역량은 모두 합의가 된 반면, 교육목표는 ‘사회복지실천의 개념과 목적에 대한 이해’등 16개중 13개, 세부내용은 ‘사회복지전문직의 역할과 정체성’등 28개중 11개 항목에서만 전문가 합의가 이루어졌다. 조사를 통해 제시된 주요 연구결과를 토대로 현 교과목지침서의 개선방안을 논의하고 추후 연구를 위한 과제를 제언하였다. The problems of social work practice education in Korea have been raised in various aspects for a long time. The main criticism is that the education of social work, which is a practical study, does not reflect the field. The purpose of this study is to develop a guideline for Social Work Practice course for competency-based social work education. We tried to derive the competencies, goals, and contents that should be covered in Social Work Practice through the Delphi method. For this purpose, a panel composed of 42 professors teaching Social Work Practice at universities across the country was surveyed three times. As a result of the survey, the panel agreed on all 10 competencies such as ‘understanding and practicing generalist social work . However, the panel agreed on 13 out of the 16 goals, such as ‘understanding the concept and purpose of social work practice . The panels agreed on only 11 items, including ‘the role and identity of social work professions’among the 28 contents. Based on the results of the survey, we discussed the improvement of the current curriculum guidelines and suggested the tasks for future research.

SWAT 모형의 적정 소유역분할 수 산정기법 : 위천유역을 대상으로

장경수(Jang Kyung Soo),장광진(Jang Kwang Jin),지홍기(Jee Hong Kee),이순탁(Lee Soontak) 대한토목학회 2007 대한토목학회 학술대회 Vol.2007 No.10

심혈관질환 관련 위험요인 및 SNP 특이 유전율 연구 : Regression of Offspring on Mid-Parent(ROMP) 방법 적용

지선하,박정용,윤지은,김민지,조은영,장양수 한국역학회 2003 Epidemiology and Health Vol.25 No.1

Purpose : The objective of this study was to estimate the heritability attributable to single-locus effects with a regression of offspring on mid-parent (ROMP) method for cardiovascular risk factors. Methods : The regression of offspring on mid-parent is determined with and without the inclusion of a single-locus effect, and the difference between the slopes of these two regression is an estimate of the heritability attributable to the single-locus effect. The study population included 1,550 family members of 295 patients, derived from cardiovascular genome center. The risk factors considered were total serum cholesterol, triglyceride, LDL cholesterol, apoAI and apoB. Heritability was estimated from the slope of the linear regression of offspring on mid-parents. Results : Estimated heritability was 35 to 46% for total cholesterol with 6.2% attributable to polymorphism S128R. For triglyceride, the estimated heritability was 47.6% with 2% attributable to polymorphism G-217A. The heritability was 36-46% for LDL-cholesterol. For LDL cholesterol, S128R specific effect was 8.7%. Estimated heritability was 62.2% for apoAI with 3.2% attributable to polymorphism G-217A and 58 to 75% for apoB with 5.4% attributable to polymorphism S128R. Conclusions : These traits were significantly associated with polymorphism S128R. These results highlight the importance of considering genetic factors in studies of cardiovascular risk factors. Unlike traditional population-based tests of association, ROMP appears to be robust with respect to population stratification.