알파인 스키 국가대표선수와 국가대표 상비군 선수의 요부 및 슬관절의 등속성 근력에 관한 비교 연구

이종희,허승은,이재문 경희대학교 체육과학연구소 2001 體育學論文集 Vol.29 No.-

The current study aims at determining the effect of fitness and suggesting basic information necessary for training the National Alpine ski team through comparing the uniform nature lumbar joint and a knee joint muscular function in 20 Alpine ski racers based on race results. We divided the group into A (National team) and B (National reserve team) groups, and we used the result obtained by a body component analysis programs such as In Body 3.0 and Biodex system 3, which were further examined statistically by SPSS/PC+ program. The difference of uniform nature lumbar joint and a knee joint muscular function from the race in each team was analyzed through Independent Samples t-test, and the results are as follows: 1. The uniform nature the absolute lumbar region of a protractor and the flexor muscular strength in National Alpine ski team was notably higher than that of National reserve team, but there was little difference in relative vague per weight. 2. The uniform nature of lumbar region muscular stamina of National Alpine ski team was comparatively higher than that of the reserve team, but there was little difference in rate of muscle. 3. The average power of uniform lumbar region in National Alpine ski team showed a sizable difference at 60 degrees per second (p〈.01), and at 180 degrees per second there was a sizable difference between groups (p〈.01). 4. The left and right protractor of uniform nature knee joint and maximum muscular strength in National Alpine ski racers was notably high, but there was little difference in relative value per weight. 5. The uniform nature left and right of protractor and muscular stamina flexor knee joint in National Apline ski racers was notably high (p〈.01), but there was little diffrence between groups in muscular stamina of the right flexor. 6. The rate of muscle of uniform nature knee joint and the rate of muscle of both of National Alpine ski racers was not much different from that of National reserve team. 7. The average power of the left and right protractor and the uniform nature knee joint of flexor of National Alpine ski racers at 60 degrees per second was notably high (p〈.01). However, though the average power of the left and right of protractor and the right of flexor was notably high at 180 deg per second (p〈.05) there was little difference in the left flexor.

우리나라 파프리카 수출단지 및 선과장의 병해충 조사

김기돈,이시원,강은하,신용길,전재용,허노열,이흥식 충남대학교 농업과학연구소 2013 농업과학연구 Vol.40 No.2

The disease and insect were surveyed locally in greenhouse, fruit packing house and store house of 51 farms in 13 towns having purpose of paprika exportation. By analysis, various disease and insect were not only founded locally but more ones detected in farms having old facilities and no natural enemy. We found 15 pathogens such as Fusarium spp., Alternaria solani, Leveilluila taurica, PepMV (Pepino mosaic virus) and TMV (Tobacco mosaic virus) in greenhouse, Fusarium spp. in fruit packing house and Penicillium spp. in store house. We found 15 insects in greenhouse such as Bemisia tabaci, rialeurodes vaporariorum and Myzus persicae in greenhouse, Hylobitelus haroldi in fruit packing house. However, the problem quarantine disease and insect for importation and exportation were not detected in inspection time.

비호지킨 림프종의 임상적 고찰

김태원,조은택,조기섭,정재용,허재봉,장영,박유환,정춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

A retrospective clinical and histologic study of 30 non-Hodgkin's lymphomas diagnosed at the Department of Hemato-oncology of the Chosun University from January 1989 to December 1993 is presented. Among total 30 cases whose sexes were mentioned, male were 18 and female were 12 and the ratio is 1.5:1. The peak incidence of non-Hodgkin's lymphoma was found in the third decade. The case distributions by Working formulation were summarized in table 3. The most common histopathologic type of non-Hodgkin's lymphoma was the diffuse large cell type of intermediate grade. The presenting symptoms at the time of first visit to the hospital were summarized in table 4. The most common symptoms were palpable mass. Lymph node enlargements were found in 87 %, and most frequently on cervical area(35%). The incidence of primary nodal lymphoma is more frequent than extranodal lymphoma, 1.2:1. The most common primary site of extranodal lymphoma is the gastrointestinal tract. In the laboratory findings, the data of hemoglobin and hematocrit were summarized in table 8, 9, Values of hemoglobin and hematocrit of female patients greater than those of male patients. The results of the immunophenotypings of nodal and extranodal lymphoma indicates that the B-cell lymphoma are predominant(B:T=1.4:1). The clinical stage was Ⅱ in 9 cases(30%) Ⅲ in 9 cases(30%), Ⅳ in 8 cases(26.7%), Ⅰin 4 cases(13.3%), 28 cases were treated with CHOP regimen. Among them, 17 cases(60.8%) achieved a complete remission. 5 cases had a partial response. The most frequent toxicities were toxic hepatitis.

Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies

Heo, Eun Jin,Cho, Young Jae,Cho, William Chi,Hong, Ji Eun,Jeon, Hye-Kyung,Oh, Doo-Yi,Choi, Yoon-La,Song, Sang Yong,Choi, Jung-Joo,Bae, Duk-Soo,Lee, Yoo-Young,Choi, Chel Hun,Kim, Tae-Joong,Park, Woong- 대한암학회 2017 Cancer Research and Treatment Vol.49 No.4

<P><B>Purpose</B></P><P>Patient-derived tumor xenografts (PDXs) can provide more reliable information about tumor biology than cell line models. We developed PDXs for epithelial ovarian cancer (EOC) that have histopathologic and genetic similarities to the primary patient tissues and evaluated their potential for use as a platform for translational EOC research.</P><P><B>Materials and Methods</B></P><P>We successfully established PDXs by subrenal capsule implantation of primary EOC tissues into female BALB/C-nude mice. The rate of successful PDX engraftment was 48.8% (22/45 cases). Hematoxylin and eosin staining and short tandem repeat analysis showed histopathological and genetic similarity between the PDX and primary patient tissues.</P><P><B>Results</B></P><P>Patients whose tumors were successfully engrafted in mice had significantly inferior overall survival when compared with those whose tumors failed to engraft (p=0.040). In preclinical tests of this model, we found that paclitaxel-carboplatin combination chemotherapy significantly deceased tumor weight in PDXs compared with the control treatment (p=0.013). Moreover, erlotinib treatment significantly decreased tumor weight in epidermal growth factor receptor–overexpressing PDX with clear cell histology (p=0.023).</P><P><B>Conclusion</B></P><P>PDXs for EOC with histopathological and genetic stability can be efficiently developed by subrenal capsule implantation and have the potential to provide a promising platform for future translational research and precision medicine for EOC.</P>

Assessment of risk factors of achieving complete versus almost complete skin clearance in patients with moderate to severe psoriasis on biologic therapy

( Eun Ji Hong ),( Jeong Yeon Hong ),( Jae Young Heo ),( Jae Yun Kim ),( Jung Eun Kim ),( Young Lip Park ),( Sul Hee Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1

Changes in High-Density Lipoprotein Cholesterol and Risks of Cardiovascular Events: A Post Hoc Analysis from the PICASSO Trial

Eun-Jae Lee,Sun U. Kwon,Jong-Ho Park,Yong-Jae Kim,Keun-Sik Hong,Sungwook Yu,Yang-Ha Hwang,Ji Sung Lee,Juneyoung Lee,Joung-Ho Rha,Sung Hyuk Heo,Sung Hwan Ahn,Woo-Keun Seo,Jong-Moo Park,Ju-Hun Lee,Jee-H 대한뇌졸중학회 2020 Journal of stroke Vol.22 No.1

Background and purpose Whether pharmacologically altered high-density lipoprotein cholesterol (HDL-C) affects the risk of cardiovascular events is unknown. Recently, we have reported the Prevention of Cardiovascular Events in Asian Patients with Ischaemic Stroke at High Risk of Cerebral Haemorrhage (PICASSO) trial that demonstrated the non-inferiority of cilostazol to aspirin and superiority of probucol to non-probucol for cardiovascular prevention in ischemic stroke patients (clinicaltrials.gov: NCT01013532). We aimed to determine whether on-treatment HDL-C changes by cilostazol and probucol influence the treatment effect of each study medication during the PICASSO study. Methods Of the 1,534 randomized patients, 1,373 (89.5%) with baseline cholesterol parameters were analyzed. Efficacy endpoint was the composite of stroke, myocardial infarction, and cardiovascular death. Cox proportional hazards regression analysis examined an interaction between the treatment effect and changes in HDL-C levels from randomization to 1 month for each study arm. Results One-month post-randomization mean HDL-C level was significantly higher in the cilostazol group than in the aspirin group (1.08 mmol/L vs. 1.00 mmol/L, P<0.001). The mean HDL-C level was significantly lower in the probucol group than in the non-probucol group (0.86 mmol/L vs. 1.22 mmol/L, P<0.001). These trends persisted throughout the study. In both study arms, no significant interaction was observed between HDL-C changes and the assigned treatment regarding the risk of the efficacy endpoint. Conclusions Despite significant HDL-C changes, the effects of cilostazol and probucol treatment on the risk of cardiovascular events were insignificant. Pharmacologically altered HDL-C levels may not be reliable prognostic markers for cardiovascular risk.

IGFBP5-derived peptide as a novel angiogenesis inhibitor for treatment of ovarian cancer

( Eun Jin Heo ),( Jae Ryoung Hwang ),( Jeong Won Lee ),( Je Ho Lee ),( Young Jae Cho ),( Bvoung Gie Kim ),( Duk Soo Bae ) 대한산부인과학회 2015 대한산부인과학회 학술대회 Vol.101 No.-

Curcumin enhances the anti-cancer effects of binimetinib on melanoma cells by inducing mitochondrial dysfunction and cell apoptosis with necroptosis

( Jae Young Heo ),( Dong Sung Kim ),( Yun Su Eun ),( Na Gyeong Yang ),( Eun Ji Hong ),( Sooyoung Kim ),( Euy Hyun Chung ),( Sang Hoon Lee ),( Moon Kyun Cho ) 대한피부과학회 2022 대한피부과학회 학술발표대회집 Vol.74 No.1

Participation and Influencing Factors in the Decision-Making of Life-Sustaining Treatment: A Focus on Deceased Patients with Hematologic Neoplasms

Jae Eun Jang,Jeong Moon Ryu,Min Hee Heo,Do Eun Kwon,Ji Yeon Seo,Dong Yeon Kim Korean Society for Hospice and Palliative Care 2023 한국호스피스.완화의료학회지 Vol.26 No.2

Purpose: This study aimed to investigate the involvement of patients who died from hematologic neoplasms in the decision-making process surrounding the withdrawal of life-sustaining treatment (LST). Methods: A total of 255 patients diagnosed with hematologic neoplasms who ultimately died following decisions related to LST during their end-of-life period at a university hospital were included in the study. Data were retrospectively obtained from electronic medical records and analyzed utilizing the chi-square test, independent t-test, and logistic regression. Results: In total, 42.0% of patients participated in the decision-making process regarding LST for their hematologic neoplasms, while 58.0% of decisions were made with family involvement. Among these patients, 65.1% died in general wards and 34.9% in intensive care units (ICUs) as a result of decisions such as the suspension of LST. The period from the LST decision to death was longer when the decision was made by the patient (average, 27.15 days) than when it was made by the family (average, 7.48 days). Most decisions were made by doctors and family members in the ICU, where only 20.6% of patients exercised their right to make decisions regarding LST, a rate considerably lower than 79.4% observed in general wards. Decisions to withhold or withdraw LST were more commonly made by patients themselves than by their families. Conclusion: The key to discussing the decision to suspend hospice care and LST is respecting the patient's self-determination. If a patient is lucid prior to admission to the ICU, considerations about suspending LST should involve the patient input.

Association between appendicular skeletal muscle mass and depressive symptoms: Review of the cardiovascular and metabolic diseases etiology research center cohort

Heo, Ji Eun,Shim, Jee-Seon,Song, Bo Mi,Bae, Hye Yoon,Lee, Ho Jae,Lee, Eun,Kim, Hyeon Chang Elsevier 2018 Journal of affective disorders Vol.238 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>The effects of skeletal muscle mass on depressive symptoms remain poorly understood, especially in the middle-aged population. We examined the relationship between skeletal muscle mass and depressive symptoms according to sex and menopausal status in the middle-aged Korean population.</P> <P><B>Methods</B></P> <P>Herein, 1,151 men and 2,176 women aged 30–64 years completed questionnaires and underwent health examinations in the Cardiovascular and Metabolic Disease Etiology Research Center study. Appendicular skeletal muscle mass (ASM) was measured via bioelectrical impedance analysis and adjusted for height squared (ASM/Ht<SUP>2</SUP>). Both continuous values and tertile groups of ASM/Ht<SUP>2</SUP> were used for analysis. Depressive symptoms were assessed using the Beck Depressive Inventory-II (BDI), and the prevalence of depressive symptoms was determined as a BDI score ≥ 20.</P> <P><B>Results</B></P> <P>Multiple logistic regression analysis using a fully adjusted model showed that depressive symptoms were more frequently observed among men in the lower ASM/Ht<SUP>2</SUP> tertile and middle ASM/Ht<SUP>2</SUP> tertile than among those in the higher ASM/Ht<SUP>2</SUP> tertile. Each 1-kg/m<SUP>2</SUP> decrease in ASM/Ht<SUP>2</SUP> was significantly associated with the presence of depressive symptoms in men. Such significant association was not observed among premenopausal and postmenopausal women.</P> <P><B>Limitations</B></P> <P>The cross-sectional nature of the study design, measurement of skeletal muscle mass and depressive symptoms only once, estimation of skeletal muscle mass using bioelectrical impedance analysis, assessing depressive symptoms by self-reported questionnaire, and potential unknown confounding variables constitute the limitations of our study.</P> <P><B>Conclusions</B></P> <P>The independent association between low skeletal muscle mass and depressive symptoms was observed in men but not in women.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Depressive symptoms were predominant in men in lower and middle ASM/Ht<SUP>2</SUP> tertiles. </LI> <LI> An association between ASM/Ht<SUP>2</SUP> and depressive symptoms was not observed in women. </LI> <LI> Maintenance of appropriate skeletal muscle mass may decrease the risk of depressive symptoms in middle-aged Korean men. </LI> </UL> </P>