뉴 비즈니스 모델을 통한 대량 소비시장 공략전략

이광현 동의대학교 경제경영전략연구소 2004 經濟經營硏究 Vol.2 No.1

The attack strategies on the large consumer market by the new business model Generally the leading companies have been adopting the strongly differentiated strategies by using the new business model Especially, the companies with strong competitive adventages now use the attack strategies on the large consumer market by the new business model Through the case study of Woongin Coway, We could find the success stories. These days, the rapidly changing environments demand us to change our traditional business model as soon as possible.

해외 전력거래소들의 전략집단 분석을 통한 한국 전력거래소의 전략방향

이광현,장찬주 국제무역학회 2002 국제무역연구 Vol.8 No.2

우리나라 전력산업구조 개편에 따라 전력산업에 경쟁개념을 도입하게 되었다. 전력산업에 경쟁을 도입한다는 것은 다수의 시장참여자가 존재하는 시장경제체제로의 전환을 의미하는 것이다. 이에 의거하여 새롭게 등장한 한국전력거래소는 경쟁적 전력시장에 참여하는 회원사, 이해관계자 집단 그리고 국민에게 엄청난 영향을 미칠 전망이다. 본 연구에서는 전략집단분석 (Strategic Group Analysis)을 통해 외국의 전력거래소들을 4개의 전략집단으로 그룹핑 하였다. 그리고 한국전력거래소가 지향해야 할 전략집단을 단기·중기차원에서 도출하여 한국전력 거래소의 단지·중기 전략방향을 제시하였다. 더 나아가 우리나라 전력거래소가 지향해야 할 선도 전력거래소들의 구체적 사례분석을 통해 한국전력 거래소가 추진해야 할 향후전략과 핵심역량강화 방안을 제시하였다. Korean government has introduced competition on power industry according to power industry restructuring. To introduce competition on power industry is to transform from monopolistic structure into market-driven system with multiple players. Conseguently, Newly created Korean Power Exchange will have heavy impact on members. interest groups and citizens which participate in the competitive power market. In this research, first, we made four groups of foreign power exchanges by using Strategic Group Analysis. Second, we found short and long term strategic directions of Korean Power Exchange(KPX) based on target strategic group. Third, we made case analysis of foreign leading power exchanges that Korean Power Exchange should follow. Lastly through case analysis. we presented future strategies of KPX and strategies of strengthening core competences.

정수기산업의 구조와 생존전략

이광현 高麗大學校産業開發硏究所 1997 産業開發硏究 Vol.5 No.-

한국 실정에 적합한 새로운 전략적 업적평가 모델 구축

이광현 高麗大學校産業開發硏究所 1998 産業開發硏究 Vol.6 No.-

핵심역량을 변수로 한 새로운 다각화 분석모델의 개발

이광현 高麗大學校 産業開發硏究所 1995 産業開發硏究 Vol.4 No.-

단기간의 저용량 Cytosine arabinoside 치료에 반응하였던 Down 증후군에 병발한 급성골수성백혈병 1례

김현수,이정호,이정찬,강정현,곽상혁,김철희,배광봉,김종숙,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

The incidence of hematologic disorders in patients with Down's syndrome is significantly increased, about 14∼30 - fold higher than in general population and includes neonatal transient abnormal myelopoieis and acute leukemias. The age of onset of leukemia in Down's syndrome is peaking first in the newborn period and then under 4 years of age. Down's syndrome with acute leukemia above the age of 20 is very rare and it's treatment oucome is unclear. The treatment of Down's syndrome with leukemia has been controversial because of toxicity and associated congenital cardiac and other abnormalities. But if treated adequately, children with Down's syndrome show a favorable response to anti-leukemia therapy. A 24-year-old man with Down's syndrome was first seen for the evaluation of anemia and thrombocytopenia. The peripheral blood morphology and bone marrow study revealed acute myelogenous leukemia, cytogenetic study of bone marrow showed trisomy 21. Beacuse of his sicioeconomic condition and medical abnormalities including deafness, visual loss, he was treated with low dose subcutaneous cytosine arabinoside(Ara-C) for 11 days. Complete remission was obtained after 37 days. The complete remission lasted for 5 months. He subsequently relapsed, and died 6 months later.

Azathioprine에 반응을 보인 류마티양 관절염에 의한 경막염(Pachymeningitis)1예

배광봉,이정호,이정찬,곽상혁,강정현,김철희,김현수,김종숙,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

Rheumatoid arthritis frequently involves the cervical spine and may lead to neurologic impairement. However, direct involvement of CNS structures by inflammatory cells has been reported infrequently. The prevalence of this complication of rheumatoid arthritis is unknown. Inflammatory CNS involvement in rheumatoid arthritis reportedly occurs in the setting of longstanding, active, erosive articular disease and is accompanied by extracranial and extraspinal nodules and vasculitis. This is diagnosed by radiologic finding of CNS nodules or meningeal thickening and by biopsy or autopsy. Treatment with corticosteroid, cytotoxic agent or surgical decompression is helpful. But the majority of patients die within several months of onset of neurologic symptom. Recently, we experienced a case of pachymeningitis caused by rheumatoid arthritis, which resolved repeatedly with azathioprine treatment.

중증 재생불량성 빈혈 환자에서 신우신염에 대한 광범위항생제치료 중에 속발한 Saccharomyces cerevisiae 진균감염 1예

김철희,이정호,이정찬,강정현,곽상혁,배광봉,김현수,김종숙,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

Most patients with aplastic anemia who do not respond to immunosuppressive treatment or are not candidates for bone marrow transplantation die of infection or bleeding. The neutropenia in acute leukemia, aplastic anemia, or occurring subsequently to chemotherapy and bone marrow transplantation increases susceptibility to infection. In general, the number of infectious episodes correlate with the degree and duration of neutropenia. Global immunosuppression produced by conditioning for bone marrow transplantation or graft-versus-host disease, is associated with unusual bacterial and fungal pathogens, or serious viral and protozoan infections. In addition, repeated treatment with broad-spectrum antibiotics is associated with the emergence of resistant organisms and fungal diseases because of the altered microbial microenvironment of the host. The incidence of invasive fungal infection caused by Saccharomycetes eerevisiae in immunosuppressed patients is very rare, compared with that of infection by candida or aspcrgillus species. Cases of Saccharomycetes cerevisiae fungemia occurring in the course of treatment with broad-spectrum antibiotics are reported in patients with extensive burn or with prosthetic valve endocarditis. We experienced a case of urinary tract infection by Saccharomycetes cerevisiae in a 27-year old female patient with severe aplastic anemia. We report the case with a review of relevant literatures.

Asthma predictive index as a useful diagnostic tool in preschool children: a cross-sectional study in Korea

Lee, Dong Hyeon,Kwon, Ji-Won,Kim, Hyung Young,Seo, Ju-Hee,Kim, Hyo-Bin,Lee, So-Yeon,Jang, Gwang-Cheon,Song, Dae-Jin,Kim, Woo Kyung,Jung, Young-Ho,Hong, Soo-Jong,Shim, Jung Yeon The Korean Pediatric Society 2020 Clinical and Experimental Pediatrics (CEP) Vol.63 No.3

Background: It is challenging to diagnose asthma in preschool children. The asthma predictive index (API) has been used to predict asthma and decide whether to initiate treatment in preschool children. Purpose: This study aimed to investigate the association between questionnaire-based current asthma with API, pulmonary function, airway hyperreactivity (AHR), fractional expiratory nitric oxide (FeNO), and atopic sensitization in preschool children. Methods: We performed a population-based cross-sectional study in 916 preschool children aged 4-6 years. We defined current asthma as the presence of both physician-diagnosed asthma and at least one wheezing episode within the previous 12 months using a modified International Study of Asthma and Allergies in Childhood questionnaire. Clinical and laboratory parameters were compared between groups according to the presence of current asthma. Results: The prevalence of current asthma was 3.9% in the study population. Children with current asthma showed a higher rate of positive bronchodilator response and loose and stringent API scores than children without current asthma. The stringent API was associated with current asthma with 72.2% sensitivity and 82.0% specificity. The diagnostic accuracy of the stringent API for current asthma was 0.771. However, no intergroup differences in spirometry results, methacholine provocation test results, FeNO level, or atopic sensitization rate were observed. Conclusion: The questionnaire-based diagnosis of current asthma is associated with API, but not with spirometry, AHR, FeNO, or atopic sensitization in preschool children.

Adequacy of Current Strategy for Surveillance of Hepatocellular Carcinoma in Chronic Hepatitis B Patients on Entecavir Treatment

( Gwang Hyeon Choi ),( Ju Hyun Shim ),( Seheon Chang ),( Ji Hyun An ),( Danbi Lee ),( Kang Mo Kim ),( Young-suk Lim ),( Han Chu Lee ),( Young-hwa Chung ),( Yung Sang Lee ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: Global practice guidelines have recommended hepatocellular carcinoma (HCC) surveillance for chronic hepatitis B (CHB) patients older than 40 years mostly using liver ultrasound every 6 months. It is well proven that a sustained reduction of hepatitis B viral load by antiviral agents is helpful in lowering the risk of HCC. The aim of this study is to examine the annual incidences of HCC in different status of CHB, and to evaluate whether current surveillance policy is a reasonable approach in patients under antiviral treatment. Methods: This study in an endemic area retrospectively included 1,955 CHB patients aged ≥40 years who started entecavir treatment between 2007 and 2012 and continued therapy for at least 6 months (mean age, 50.3±10.7 years; 1,220 males; 932 with cirrhosis; 452 with HBeAg; and 623 with Child-Pugh class A). No patients had previous history of HCC and decompensated liver function. We measured incidence rates of HCC according to the presence of HBeAg or cirrhosis, and statistically investigated host and viral factors related to HCC occurrence. Results: A total of 237 HCC cases were identified during a median follow-up of 4.6 years (9,174 person-years). Initial HCCs were detected usually at early stages (BCLC 0 or A in 199 patients [84%]) The overall HCC incidence rate was 2.58 per 100 person-years of observation. The annual risk of developing HCC was higher in sets with male gender (3.29% vs. 1.45%); older age (1.38% for <50 years, 3.44% for 50-60 years, and 4.16% for ≥60 years); positive HBeAg (4.70% vs. 2.51%); and cirrhosis (5.13% vs. 0.50%). The cumulative incidence of HCC at 3 and 5 years was 6.45% and 9.92%, respectively for the entire patients; 7.87% vs 4.03 and 12.21% vs. 6.04%, respectively for men and women (Ps<0.05); 7.17% vs. 5.86% (P=0.24) and 9.90% vs. 9.94% (P=0.97), respectively for HBeAg-positive and negative patients; and 12.45% vs. 0.98% and 18.88% vs. 1.76%, respectively for patients with and without cirrhosis (Ps<0.05). Multivariate Cox analysis revealed that male gender, older age, HBeAg positivity, high ALT and cirrhosis were significant predictors of HCC development (hazard ratios 2.82, 1.07, 1.45, 0.89, and 6.41, respectively; Ps<0.05), as was neither pretreatment viral load (0.96) nor undetectable HBV NDA (<200 IU/mL) at 12 month (0.89). Conclusions: The annual incidence rates for HCC were not unfortunately low in CHB patients in spite of viral suppression with the potent drug, and met the above cost-effective criteria for HCC screening (0.2-1.5% per year). Based on our findings, HCC should be regularly surveilled in patients with CHB, regardless of use of antivirals or presence of cirrhosis.