http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Characteristics of Rapid Pyrolysis for Upgrading Heavy Oils in a Circulating Fluidized Bed Reactor
Go, Kang Seok,Seo, Myung Won,Guahk, Young Tae,Chang, Heyn Sung,Nho, Nam Sun,Kim, Kwang Ho,Kim, Yong Ku,Lee, Jae Goo American Chemical Society 2017 ENERGY AND FUELS Vol.31 No.6
<P>The hydrodynamic velocity and effect of the reaction temperature on the cracking performance Were investigated for the production of light oil through the rapid pyrolysis of heavy oil in a circulating fluidized bed reactor. From this study, the gas velocity in the loop seal to prevent slugging, the transport gas velocity to form a dense phase of solids on the bottom Of the -' riser, and the minimum bubbling fluidization velocity for stable solid circulation in the reheater were determined. Under the steady supply of feed through the internal mixing with steam inside the feed nozzle, the reactivity for a terriperattire change from 527 to 574 degrees C was investigated. As a result, the residue (>535 degrees C) conversion and liquid yield of up to 71.1 and 78.2%, respectively, were found. The maximum impurity rernoval rates for sulfur, Conradson carbon residue, and metals (nickel and vanadium) were found to be 1.8.7, 50.4, and 83.6%, respectively.</P>
Go, Ga-Yeon,Jo, Ayoung,Seo, Dong-Wan,Kim, Woo-Young,Kim, Yong Kee,So, Eui-Young,Chen, Qian,Kang, Jong-Sun,Bae, Gyu-Un,Lee, Sang-Jin The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.3
Background: As a process of aging, skeletal muscle mass and function gradually decrease. It is reported that ginsenoside Rb1 and Rb2 play a role as AMP-activated protein kinase activator, resulting in regulating glucose homeostasis, and Rb1 reduces oxidative stress in aged skeletal muscles through activating the phosphatidylinositol 3-kinase/Akt/Nrf2 pathway. We examined the effects of Rb1 and Rb2 on differentiation of the muscle stem cells and myotube formation. Methods: C2C12 myoblasts treated with Rb1 and/or Rb2 were differentiated and induced to myotube formation, followed by immunoblotting for myogenic marker proteins, such as myosin heavy chain, MyoD, and myogenin, or immunostaining for myosin heavy chain or immunoprecipitation analysis for heterodimerization of MyoD/E-proteins. Results: Rb1 and Rb2 enhanced myoblast differentiation through accelerating MyoD/E-protein heterodimerization and increased myotube hypertrophy, accompanied by activation of Akt/mammalian target of rapamycin signaling. In addition, Rb1 and Rb2 induced the MyoD-mediated transdifferentiation of the rhabdomyosarcoma cells into myoblasts. Furthermore, co-treatment with Rb1 and Rb2 had synergistically enhanced myoblast differentiation through Akt activation. Conclusion: Rb1 and Rb2 upregulate myotube growth and myogenic differentiation through activating Akt/mammalian target of rapamycin signaling and inducing myogenic conversion of fibroblasts. Thus, our first finding indicates that Rb1 and Rb2 have strong potential as a helpful remedy to prevent and treat muscle atrophy, such as age-related muscular dystrophy.
Ginsenoside Rg1 from Panax ginseng enhances myoblast differentiation and myotube growth
Go, Ga-Yeon,Lee, Sang-Jin,Jo, Ayoung,Lee, Jaecheol,Seo, Dong-Wan,Kang, Jong-Sun,Kim, Si-Kwan,Kim, Su-Nam,Kim, Yong Kee,Bae, Gyu-Un The Korean Society of Ginseng 2017 Journal of Ginseng Research Vol.41 No.4
Background: Ginsenoside Rg1 belongs to protopanaxatriol-type ginsenosides and has diverse pharmacological activities. In this report, we investigated whether Rg1 could upregulate muscular stem cell differentiation and muscle growth. Methods: C2C12 myoblasts, MyoD-transfected 10T1/2 embryonic fibroblasts, and HEK293T cells were treated with Rg1 and differentiated for 2 d, subjected to immunoblotting, immunocytochemistry, or immunoprecipitation. Results: Rg1 activated promyogenic kinases, p38MAPK (mitogen-activated protein kinase) and Akt signaling, that in turn promote the heterodimerization with MyoD and E proteins, resulting in enhancing myogenic differentiation. Through the activation of Akt/mammalian target of rapamycin pathway, Rg1 induced myotube growth and prevented dexamethasone-induced myotube atrophy. Furthermore, Rg1 increased MyoD-dependent myogenic conversion of fibroblast. Conclusion: Rg1 upregulates promyogenic kinases, especially Akt, resulting in improvement of myoblast differentiation and myotube growth.
Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea
Yong-Hyun Kim,Byung-Joo Park,Hee-Seop Ahn,Sang-Hoon Han,Hyeon-Jeong Go,Dong-Hwi Kim,Joong-Bok Lee,Seung-Yong Park,송창선,이상원,최인수 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.2
Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an importantreservoir of these genotypes. A survey of 14 pig farms in Korea revealed HEV RNA in 30 of 148 (20.3%) fecal samples. HEV-3a and HEV-4csubtypes were identified in five pig farms (35.7%) and two pig farms (14.3%), respectively. Phylogenetic analysis indicated that the isolatedHEV strains were closely related to previously reported zoonotic strains in Korea. The results of the genetic analysis partially explain thepossible source of the zoonotic transmission of HEV to humans in Korea.
Sung, Ki Sa,Go, Yoon Young,Ahn, Jin-Hyun,Kim, Young Ho,Kim, Yongsok,Choi, Cheol Yong Elsevier 2005 FEBS letters Vol.579 No.14
<P><B>Abstract</B></P><P>Homeodomain-interacting protein kinase 2 (HIPK2) interacts with and phosphorylates various transcription factors that are critical regulators of cell fate decisions and apoptosis during development. Here we show that lysine 25 of HIPK2 is the major sumoylation site, both in vitro and in vivo, and that the sumoylation of this site occurs in a phosphorylation-dependent manner. This became clear with the finding that kinase-dead HIPK2 (K221R) could not be efficiently sumoylated in vitro. The sumoylation of HIPK2 resulted in the disruption of its interaction with a Groucho corepressor. Consequently, sumoylation inhibited the regulatory activity of HIPK2 on the Groucho-mediated repression of transcription, whereas not on p53-mediated transactivation. These results suggest that phosphorylation-dependent sumoylation enables HIPK2 to drive different target gene transcription by means of differential interactions with its binding partners.</P>
( Yong Ju Kim ),( Min Ho Song ),( Sang In Lee ),( Ji Hwan Lee ),( Han Jin Oh ),( Jae Woo An ),( Se Yeon Chang ),( Young Bin Go ),( Beom Jun Park ),( Min Seok Jo ),( Chang Gyu Lee ),( Hyeun Bum Kim ),( 한국축산학회(구 한국동물자원과학회) 2021 한국축산학회지 Vol.63 No.4
The objective of this study was evaluation of pig behavior changes related to temperature, relative humidity, volatile organic compounds (VOCs), and illuminance. A total of 24 growing pigs ([Yorkshire × Landrace] × Duroc) were used in the experiment. A sensor was installed at a height of 0.5 m in the center of the pig house. In experiment 1, temperature was changed every four days to 18℃ (T1), 22℃ (T2), 26℃ (T3), and then 30℃ (T4). In experiment 2, relative humidity was adjusted to 45% (low humidity [LH]), 60% (middle humidity [MH]), and then 75% (high humidity [HH]) for four days. In experiment 3, after cleaning the pig house just before experiment, only minimal ventilation was provided. VOCs and pig behaviors were observed for 7 days without cleaning the pig house. In experiment 4, three light bulbs of 40 W (470 lumens / 45 lx; low illuminance [LI]), 75 W (1,055 lumens / 103 lx; middle illuminance [MI]), and 100 W (1,521 lumens / 146 lx; high illuminance [HI]) were used for four days each. Pig behavior analysis was performed for following criteria : Feed intake, Standing, Lying, Sitting, Drink water, Rooting, Posture transition (lying-standing), Posture transition (standing-lying), Wallowing, and Biting. In experiment 1, feed intake time was lower (p < 0.05) for the T3 than other treatment groups. Standing time was highest (p < 0.05) for the T1 and lowest (p < 0.05) for the T3. Lying time was shorter (p < 0.05) in T1 and T2 compared to T3 and T4. Drinking frequency was higher (p < 0.05) for the T4 than other treatment groups. In experiment 2, the frequency of rooting and wallowing increased (p < 0.05) with increasing humidity. LH showed the lowest (p < 0.05) rooting frequency and HH showed the highest (p < 0.05) rooting frequency. In experiment 3, VOCs concentration did not (p > 0.05) change pig behavior. In experiment 4, lying time was the longest (p < 0.05) at LI and shortest (p < 0.05) at HI. Therefore, pig behavior is heavily influenced by the environment, especially temperature and humidity. However, correlation between pig behavior to VOCs and illuminance seems to be needed more research.