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        혈관질환 정보관리 시스템

        김동익,김덕경,허세호,이병붕,김용신,김은숙,문지영,도영수,신성욱,김동수,김만태,진재욱,김용신 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1

        As medical technology progresses rapidly, there is a rise in the average age along with the Korean dietary lifestyle becoming more westernized, which leads to an increase in the number of vascular disease patients in Korea. Thus, we need to manage the medical information of a disease systematically in order to diagnose and treat constructively. However, since there has been no standardized method of man agement to date, a great deal of information could not be properly utilized nor studied. Therefore, the departments of Cardiology, Radiology and Neurology of Samsung Seoul Hospital recently got together to develop an information management system called the Vascular Data System. This program was developed to be run on win98 O/S, upper Pentium Ⅲ, and upper 128 MB Memory, and its source code is Dephi 4.0. It was configured for the user to set the configurations as well as do a variety of search and analysis. If this program were to be updated continuously, it may be used extensively as well as in various parts of clinical research activities.

      • 最小流動化速度에 關한 實驗的 考察

        申東秀 啓明大學校 産業技術硏究所 1990 産業技術硏究所 論文報告集 Vol.13 No.1

        The minimum fludization velocities and maximum pressure drops of 0.241 - 0.588 ㎜ glass beads, 0.293 - 0.433 ㎜ sand, 0.174-0.180 ㎜ alumina particles, and 0.054-0.149 ㎜ iron powder were measured in an air fluidized bed of 0.0667 m inside diameter. The observed minimum fluidization velocities and maximum pressure drops were compared with corresponding equations proposed by different investigators. The observed minimum fluidization velocities were in agreement with Wen and Yu equation within 20%, Leva equation within 23%, and Baerg equation within 15%. The observed maximum pressure drops were in good agreement with Parent equation and Ergun equation.

      • 시멘트 제품군의 전과정평가

        신동희,정재수,이건모 한국전과정평가학회 2002 한국전과정평가학회지 Vol.4 No.1

        국내산업계에서 범용적으로 생산되는 시멘트 제품군에 대하여 원료채취부터 제품제조까지에 대한 전과정평가를 수행하였다. 대상제품군은 국내 산업현황을 바탕으로 1종 포틀랜드 시멘트, 2종 포틀랜드 시멘트, 3종 포틀랜드 시멘트, 5종 포틀랜드 시멘트 및 고로슬래그 시멘트를 선정하였다. 각 대상 제품군별 국내 생산량이 큰 기업을 선정하여 전과정 목록분석을 수행하였다. 데이터는 현장 데이터를 적용하였으며, 현장 데이터 취득이 어려운 경우 데이터베이스를 사용하였다. 영향평가는 분류화, 특성화, 정규화 및 가중치부여 단계로 수행하였다. 환경영향평가지수는 1종 포틀랜드 시멘트, 2종 포틀랜드 시멘트, 3종 포틀랜드 시멘트, 5종 포틀랜드 시멘트 및 고로슬래그 시멘트공정이 각각 6.53E-05, 4.81E-05, 4.39E-05, 4.84E-05 및 3.84E-05로 나타났다. CO2에 의한 지구온난화가 전체 환경영향의 대부분을 차지하였다. A life cycle assessment has been conducted from raw material acquisition to manufacturing for cement products in korea. The product category included portland cement - Type Ⅰ, Type Ⅱ, Type Ⅲ and Type Ⅴ - and Blast furnace cement. The major manufacturing companies were chosen for each product category and conducted life cycle inventory analysis. Generally, Site-specific Data was applied. If it's not impossible, database was used. Impact assessment was carried out consecutively as classification, characterization, normalization and weighting. The eco-indicators of portland cement - Type Ⅰ, Type Ⅱ, Type Ⅲ and Type Ⅴ - and Blast furnace cement were 6.53E-05, 4.81E-05, 4.39E-05, 4.84E-05 and 3.84E-05, respectively. Global warming from CO2 was major contributor of product category.

      • 北韓 「合營法」의 綜合的 批判

        申東秀 단국대학교 교육대학원 1985 敎育論叢 Vol.1 No.-

        The real objects of the NK's joint venture law are to supplement the present economic system so that the hireditary succession of Kim Ilsung to his son might be easily achieved, to approach the way to narrow th economic gab between the south and the north Korea, to search for an alternative to get more of economic aids than it gets from the communist countries, and to go with the current international desire for peace on the Korean peninsula. Despite such opening gesture of north Korea, it is doubtful if the law could attract many Western countries because NK holds far more foreign debts than it can pay and the market of the NK is much smaller than that of the PRC. Though the relations between the south and the north Korea seem to change after the law is put into practice, the prospects for better cmprovements of the relations between the two sides are not bright because the relations can only be improved when a co-existential order is established and the present political system is admitted by both sides, the homogeneousness of the people is realized through gradual and bilateral intercourse in every field. It should be noticed that NK's joint venture law was announced on the stage of its political transition to a hireditary succession of Kim Jungil, son of Kim Ilsung, and, therefore, it may take a considerably long time for the law to be put into practice throughout the peninsula.

      • 자동 문턱치 방법을 이용한 밀리미터파 영상의 은닉된 물체 영역 검출

        이동수,염석원,손정영,김신환 대구대학교 정보통신연구소 2010 情報通信硏究 Vol.7 No.1

        본 논문은 수동형 밀리미터파 영상 시스템을 이용하여 은닉된 물체의 영역을 검출에 관한 연구이다. 밀리미터파 영상은 악천후에도 영상 촬영이 가능하고 플라스틱, 종이, 나무, 옷, 머리카락 같은 특유한 물질들을 투과한다. 그리고 밀리미터파는 금속과 특수한 인공 구조물에 대한 반사율이 높기 때문에 은닉된 물체를 쉽게 검출할 수 있다. 본 논문에서는 밀리미터파 영상에서 은닉된 물체 검출의 영상 분할을 자동 문턱치 방법으로 나타낸다. 본 논문에서는 8㎜ 파장을 수평과 수직 편광 방향으로 수신하는 두 채널에서 획득된 밀리미터파 영상을 Gonzalez와 Otsu 방법으로 영역 분할을 한다. 실험 결과는 Gonzalez과 Otsu 방법 모두 은닉된 물체 영역의 형태를 잘 분리하지만 Otsu 방법이 노이즈와 몸체 영역의 경계 부분이 안정적으로 영역 분할됨을 보인다. We address an image segmentation method to detect concealed objects captured by passive millimeter wave (MMW) imaging. Passive MMW imaging can create interpretable imagery on the objects concealed under clothing. Due to the penetrating property of the MMW imaging, the MMW imaging system is often employed for the security and defense system. In this paper, we develop automatic thresholding methods for the segmentation of concealed objects detected by PMMW imaging. The automatic thresholding method is useful for the image with bimodal distributions. We compare several thresholding methods for two MMW channel images which have 8 mm-horizontal and 8 mm-vertical polarization, respectively. The experimental results show that concealed weapon area is well segmented from the background body by the presented methods.

      • 유한요소법을 이용한 밸브 스프링 리테이너의 형상설계

        신혁수, 김동범, 박진근, 이인환, 조해용 충북대학교 산업과학기술연구소 2013 산업과학기술연구 논문집 Vol.27 No.2

        A valve spring retainer is a small disc and located at intake and exhaust valve stem of engine. The retainer supports a valve spring and transmits spring force to a valve. Force is applied to the retainer repeatedly by a rocker arm. Durability of the retainer is an important factor of performance. Weight of retainer affect dynamic performance of engine. Therefore, optimal strength and weight of the retainer design are needed. In this study, stress distribution and fracture load of retainer were analyzed by using FEM to design optimal strength and weight. Static load test was simulated by using commercial FEM code DEFORM-3D. Shapes of the retainer to reduce weight were designed and analyzed to verify validity of it. Simulated results and experimental ones were compared

      • KCI등재후보

        국내 조혈모세포이식 환자에서 Human Cytomegalovirus gB 유전형의 분포와 질환과의 연관성 : 예비 보고

        최수미,김진희,이동건,박선희,최정현,유진홍,박철민,이종욱,민우성,황응수,신완식,김춘추 대한감염학회 2007 감염과 화학요법 Vol.39 No.2

        목적 : 사람 거대세포바이러스(Human cytomegalovirus, 이하 HCMV) glycoprotein B (gB)는 UL55 유전자에 의해 부호화되는 당단백으로, UL55 유전자의 염기서열변화에 따라 4가지 유전형으로 나뉜다. 본 연구에서는 국내 조혈모세포이식 환자들에서 HCMV gB 유전형의 분포와 그 특성을 알아보고, gB 유전형에 따라 특정 HCMV 질환 발생과 연관이 있는지 그 임상적 의미를 분석해 보고자 하였다. 재료 및 방법 : 동종 조혈모세포이식 환자 52명의 혈액검체 94개에 대해, Chou 등이 제시한 방법에 따라, 먼저 UL55 유전자 부위를 nested PCR로 증폭한 후, RsaI과HinfI으로 Restriction fragment length polymorphism(RFLP) 분석을 시행하였다. 결과 : gB type 1은 73.1% (38/52), gB type 2는 13.5%(7/52), gB type 3는 1.9% (1/52), gB type 1과 type 2에 의한 혼합감염은 9.6% (5/52)로 나타났다. gB type 4는 관찰되지 않았다. 1명(1.9%)에서 gB 유전형을 결정할 수 없었는데, RFLP 패턴으로 보아 Trincado 등이 제시한 gB type 7에 해당하는 것으로 생각되었고, 이 새로운 아형에 대해서는 현재 염기서열 분석 중이다. 52명 중 5명(9.6%)에서 HCMV 질환이 발생하였고, 3명에서 HCMV 폐렴, 1명에서 망막염과 위장관염, 나머지 1명에서 망막염이 발생하였다. 5명 중 HCMV 질환과 관련하여 사망한 예는 없었고, 감염된 HCMV는 모두 gB type 1이었다. HCMV gB유전형과 HCMV 질환 발생 사이에 유의한 연관성은 없었고, 단일 주에 의한 감염과 혼합감염에 따른 HCMV 질환발생 사이에도 유의한 연관성은 관찰되지 않았다. 자료 분석 중 gB type 2에 감염되어 있던 환자에서 gB type 1에 재감염 되면서 발열, 간효소 수치 상승 및 pp65 HCMV 항원혈증이 나타난 예가 있었다. 결론 : 연구결과 gB type 1이 아주 우세하고, gB type 4는 검출되지 않았으며, 혼합감염의 빈도가 비교적 낮은 분포를 보였다. 이는 외국의 보고와는 다른 국내 조혈모세포이식 환자에서의 독톡한 감염 양상으로 추정된다. 본 연구에서 HCMV gB 유전형과 질환 발생과의 연관성을 밝힐 수는 없었으나, HCMV 유전형에 대한 연구는 바이러스 감염의 발병기전이나 전파 경로 및 양식과 같은 역학적 연구에 중요한 자료가 될 것이다. 현재 더 많은 수의 조혈모세포이식 환자를 대상으로 연구가 진행 중에 있으며, 앞으로 다른 질환군의 환자나 건강한 잠복 감염자에서의 추가 연구가 필요할 것으로 생각된다. Background : Human cytomegalovirus (HCMV) glycoprotein B (gB) is the major envelope glycoprotein, encoded by the UL55 gene. Based on sequence variation in the UL55 gene, HCMV can be classified into four gB genotypes. Previous studies have suggested an association between HCMV gB genotypes and clinical outcome in the immunocompromised hosts. The goal of this study was to determine the distribution of HCMV gB genotypes and the effect of gB genotype in the developement of HCMV diseases in hematopoietic stem cell transplant (HSCT) recipients in Korea. Materials and Methods : DNA was extracted from 94 blood specimen of 52 allogeneic HSCT recipients with HCMV infection. HCMV gB genotype was determined using polymerase chain reaction to amplify a region of UL55, followed by restriction fragment length polymorphism (RFLP) analysis based on RsaI and HinfI digestion. Results : The distribution of gB types were as follows: gB1, 73.1% (38/52) of patients; gB2, 13.5% (7/52); gB3, 1.9% (1/52) and mixed infection (gB1 and gB2), 9.6% (5/52). While gB4 was not detected, a new genotype (described as gB7 by Trincado et al, 2000) was identified on the basis of their RFLP pattern. During average 708 days’ follow up period, HCMV diseases developed in 5 patients. All of them had gB1 genotype. There was no statistically significant association between the incidence of HCMV diseases and the gB genotypes. Re-infection with gB1 strain was detected in one patient who had been previously infected with gB2. This episode was associated with fever, elevated liver enzyme and positive antigenemia. Conclusion : HCMV gB1 was the dominant genotype and no gB4 was detected in allogeneic HSCT recipients in Korea, which is an unique pattern compared with the previous reports. Although we can not find significant association between the HCMV diseases and the gB genotypes, genotyping of HCMV will serve in the study of pathogenesis and transmission of this virus in transplant patients. Further study is underway with large study population.

      • KCI등재후보

        표면근전도와 전자각도기를 이용한 자동차 부품 조립작업 위험요인 평가

        강동묵,이철호,,신용철,김은아,우지훈,조병만,이수일 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

        Objectives: As automobile part manufacturing is characterized by high speed and high repetition, observation methods which are usually utilized for static posture are inappropriate to evaluate musculoskeleatal risk factors. This study quantified the risk factors of musculoskeletal disorders on the forearm and suggested exposure limits by estimating the risk factors using surface electromyography (EMG) and electrogoniometer. Methods: Ten percent of the total workers at 3 automobile part manufacturing factories were randomly selected, and 99 male workers were recruited as study subjects. The study was conducted during May 2003 to September 2004. The workers were equipped with electrogoniometers on the wrist and the elbow, surface EMGs on the skin of the flexor digitorum superficialis (FDS) and extensor carpi radialis (ECR) muscles, and the heart beat recorder during work as indicators of joint movement, local muscle tension and physical work load, respectively. Results: After controlling for age, body mass index and job stress, wrist flexion maximum angle, FDS relative activity (RA) and ECR RA were significantly associated with forearm musculoskeletal symptoms. The odds ratios of the forearm were 5.0(95% CI: 1.1-22.7), 14.0(95% CI: 1.5-128.8) and 7.3(95% CI: 1.1-49.4) for wrist flexion maximum angle more than 76˚, FDS RA more than 2.8%, and ECR RA more than 3.5%, respectively. Conclusions: Joint angle and focal muscle activity were associated with forearm musculoskeletal symptoms. To reduce forearm musculoskeletal symptoms among automobile part manufacturers, the wrist flexion angle, and FDS and ECR activity need to be reduced below the guidelines recommended in this study.

      • KCI등재

        Neodymium:Yttrium-Aluminium-Garnet(Nd:YAG)레이저 照射가 弗化錫 局所塗布에 미치는 效果에 關한 實驗的 硏究

        민신홍,손동수 大韓小兒齒科學會 1986 大韓小兒齒科學會誌 Vol.13 No.1

        The purpose of this study is to determine the optimum range of laser energy density at which we may obtain maximum degree of acid resistant activities without damaging the tooth enamel surfaces in the presence of 10% stannous fluoride solution. Beam of CW Nd: YAG laser was irradiated perpendicularly at each 7 different energy levels range from zero to 60 joules/㎠ with an increment of 10 joules/㎠ on the smooth enamel surface of the extracted noncarious human first bicuspid. The author had investigated the tooth surfaces with a Scanning Election Microscope, and at the same time examined the fluoride contents with an Energy Dispersive Analysis for X-ray, and then, examined acid resistant activities with a Spectrophotometer. The results were as follows: 1) Laser energy density of 30-40 J/㎠ produced the fusion of the enamed surfaces. 2) Laser energy density of 50-60 J/㎠ produced the cracks and porous enamed surfaces. 3) Laser irradiated groups were contained high fluoride contents. The more energy increased, the more fluordie contents increased. 4) Laser energy density of 40 J/㎠ yields the high acid resistant activities. 5) The fluoride contents were increased by laser irradiation.

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