Treatment of Keratocystic Odontogenic Tumors in Nevoid Basal Cell Carcinoma Syndrome

Ryu, Hyun-Ho,Shin, Dong-Yoon,Ryu, Seok-Hwan,Kim, Taek-Woo,Lee, Jong-Bum,Kim, Bok-Joo,Kim, Chul-Hoon Korean Association of Maxillofacial Plastic and Re 2014 Maxillofacial Plastic Reconstructive Surgery Vol.36 No.1

Nevoid basal cell carcinoma syndrome (NBCCS) is inherited as an autosomal dominant trait with variable conditions, including multiple basal cell carcinoma, numerous keratocystic odontogenic tumors (KOTs) in the jaws, ectopic calcification of the falx cerebri, bifid ribs, macrocephaly, kyphoscoliosis, cleft palate, frontal and temporal bossing, mild ocular hypertelorism, mild mandibular prognathism, vertebral fusion, and so on. A 16-year-old boy visited the Dong-A University Medical Center, requiring diagnosis and treatment of multiple cystic lesions. He presented with many conditions related to NBCCS, including multiple KOTs, bifid rib, cleft lip, frontal bossing, mild ocular hypertelorism, and mild mandibular prognathism. No characteristic cutaneous manifestations (nevoid basal cell carcinoma) were observed in this patient. We report on a case of multiple KOTs associated with NBCCS with a review of the literature.

等誘電性 2成分溶媒系에서 鹽化알킬카르보닐의 加알코올 分解反應

柳俊夏,金良姬,成大東,朴現錫,嚴泰燮 東亞大學校 1990 東亞論叢 Vol.27 No.1

The nucleophilic substitution reactions of alkanecarbonyl chlorides with alchohols in the polar aprotic solventls have been studied by means of the conductimerical method. The results are as follows; 1. The order of magnitude of the second-order rate constants in the same substrate is acetyl carbonyl chloride>propionyl choride>X-valeryl iso-vareryl chloride. This is in full accord with the inductive effect by means of the polarizability effect that is due to connect with the σ-bond of alkyl radical to neigboring atom. 2. The reactionis proceeded through the S2 reaction mechanism from the analysis of the values of m and ℓwhich are obtained from the extended Grunwald-Winstein equation. 3. From the prediction on the More O'Ferrall plot the reaction mechanism is favored to the SN route. 4. As shown in the quantum mechanical model, the reaction mechanism is shown to favor an associative S2. 5. The reaction mechanism is in accord with an associative S2 reaction mechanism in consideration of the solvent effect exactly.

한국인의 치과의원 내원요인 조사 연구

류영욱,배현숙,성진효,김동기 조선대학교 구강생물학연구소 2003 Oral Biology Research (Oral Biol Res) Vol.27 No.1

According to the increase of the number of dental clinics and the level of the patient's recognition about oral health care, the need for effective clinical management to provide proper oral health care service to the patients has arisen. Many patients has selected the dental clinics based on self estimation or other recommendation. Therefore the main reasons for selecting the dental clinic by the patients needed to analyze, So we conducted the survey which prepared questionnaire were provided to 700 subjects and collected data related to the factors for patients to select the dental clinics. The results were as follows : 1. In the view of access, the place easy of access and parking capacity was important to the degree of 43.0% and 30.8%, respectively. 2. In relation to the dentist, the quality of treatment and the trust was important to the degree of 80.7% and 71.3%, respectively. 3. Modern clinical facility was occupied 65.5% in the basic environment factors. 4. In the basic factors, kindness and cleanliness was 76.6% and 76.7%, respectively, and it showed that these factors were more important than the number of the clinicians and comfort of the waiting room. 5. In relation to the satisfaction of treatment, cheaper treatment cost, decreased waiting tine, the variety of treatment tine and various payment method were important to the degree of 51.8%, 48.4%, 42.8% and 39% in order.

1,4-나프토퀴논 유도체의 항균 및 항진균 작용

유충규,류재천,정세영,김동현 梨花女子大學校 藥學硏究所 1992 藥學硏究論文集 Vol.- No.2

In order to evaluate the antimicrobial effect of 2,3-substituted-1.4-naphthoquinone derivatives, we newly synthesized several 2-chloro, 2-bromo and 2-hydroxy-1, 4-naphthoquinones and subjected to antibacterial and antifungal activites, in vitro, against Escherichia coli NIHJ, Staphylococcus aureus ATCC6538p, Candida albicans 10231, Aspergillus niger 1231 and Tricophyton mentagrophytes 6085. Among these derivatives 3, 9, 18 and 23 showed the potent antibacterial activities. 18, 23 and 28 have the antifungal activities. However, these compounds have no significant hemolytic activity at concentrations higher than that required for showing the antibacterial and antifungal activities.

가상현실 고소공포증 치료시스템을 위한 생체신호 분석에 관한 연구

柳宗賢,白承和,白承殷,金東完 明知大學校 産業技術硏究所 2005 産業技術硏究所論文集 Vol.24 No.-

Acrophobia is a symptom of feeling an abnormal fear of heights. Medications or cognitive-behavior methods have been mainly used to treat the acrophobia. In these days the virtual reality technology has been applied to treat such an anxiety disorders. But former acrophobia treatment systems use only patient's score of the questionary to appraise. The new system developed in this thesis uses not only patient's score of the questionary but also biomedical signals such as HR, GSR amplitude to increase the objectivity and quantitativity. The experimental results show that HR and GSR amplitude are useful for decision of acrophobia. We will apply this system to the acrophobia patient and be able to offer better medical treatment for mental illness in near future.

우리나라 農産物마아케팅에 관한 硏究

柳東鉉 충남대학교 경상대학부설 경영경제연구소 1984 경영논집 Vol.6 No.2

Dabsyl Chlorides의 親核性 置換反應

成大東,朴現錫,柳俊夏,金良姬,李鍾八,嚴泰燮 東亞大學校 1990 東亞論叢 Vol.27 No.1

Kinetic studies of nuclsophilic substitution reaction of dabsyl chloride with pyridines have been investigated at 30℃ in a range of methanol-acetonitrile bianary solvent mixtures. The order of magnitude fo reactivity is β-picoline > pyridine > 1.5-N D A > α-picoline to react with dabsyl chloride, especially in case of α-picoline, the reactivity revealed lower than others, it is suggestd that nitrogen atom of pyfidine ring has a steric hinderance by the neightboring methyl group. The value of ρ(-0.96∼4.59) and β(0.36∼0.67) associated with a change of substituent in the nucleophile are large and indicate a realtively advanced bond formation in the transition state. Solvatochraomic correlations were predicted the importance of bond formation transition state, showing a greater contribution of polaritypolarizability (π*) lone paired to hydro-gen bond donar acidity (α). We conclude that the reaction of dabsyl chloride with pyridine proceed via S2 type reaction mechanism, as well as the reaction of dansyl chloride pyridine.

Nalidixic acid 내성 장티푸스균에 대한 항생제 시간-살균 연구

김동민,윤나라,정종훈,류현호 대한감염학회 2008 감염과 화학요법 Vol.40 No.4

Background : We recently encountered a case of typhoid fever in a patient who visited us after travelling India. The patient received ciprofloxacin therapy, but developed typhoid pneumonia and typhoid hepatitis, and nalidixic acid resistance Salmonella Typhi (NARST) was identified. The aim of this study was to assess the in vitro efficacy of several antimicrobial combinations, which are commonly used in clinical practice. Materials and Methods : Time-kill studies were performed for a clinical NARST strain to evaluate synergy. Synergy was defined as a ≥2 log_10 decrease (l00-fold drop) in CFU per mL at 24 hours by a drug combination compared to the most active constituent. Results : The combination regimen of cefotaxime plus ciprofloxacin significantly reduced the bacterial counts (>3 log CFU) at 3/4 MIC and at 24 hours compared to the ciprofloxacin or cefotaxime alone and showed synergistic effect against a NARST strain. Conclusions : In conclusion, our time-kill studies showed that ciprofloxacin plus cefotaxime was the best in vitro combination against a NARST. This combination may improve efficacy compared to fluoroquinolone alone in typhoid fever patient with NARST. Time kill studies with more NARST strains and clinical studies are required to test the relevance of our findings

관절성형술 및 측두근막 이식술을 이용한 악관절 강직증의 치험례

진택현,오승환,류동목,김여갑,이상철 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

This is a case of bony ankylosis of right temporomandibular joint with mild facial asymmetry resulted from trauma, which bring about the right condylar fracture, and corrected by interpositional arthroplasty with temporal fascia flap and coronoidectomy. The postoperative results were functionally and esthetically good, but continued osbervation is necessary to evaluation of abnormal bony growth and reankylosis.

기포유동층 반응기 내에서 천연제올라이트를 사용한 아연계 탈황제의 반응특성연구

김동현,정용길,박노국,이종대,전진혁,류시옥,이태진 한국공업화학회 2003 응용화학 Vol.7 No.2

To improve attrition resistance, calcium oxide was added to durable ZZF sorbent. It was named ZZFCa sorbent. The reactivity of ZZFCa sorbent was investigated in the fluidized-bed reactor. The influencesof the sulfur capacity and the regeneration time for various fluidization velocities from 0.07㎧ to 0.20㎧ were investigated for 5-cycles. As a result, ZZFCa sorbent appeared the high sulfur capacity abouve 10gS/100g sorbent. The sulfur capacity of ZZFCa was maintained, although fluidization velocities increased.