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      • KCI등재

        The prediction of the tooth size in the mixed dentition for Korean

        Moon, Sung-Hwan,Kim, Seong-Oh,Yu, Hyung-Seong,Choi, Byung-Jai,Choi, Hyung-Jun,Lee, Jae-Ho 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

        이번 연구의 목적은 혼합치열기 아동에서 미맹출된 견치와 소구치의 크기를 예측하는데 있어서 한국인에 맞는 방정식을 만들기 위함이다. 미맹출 치아의 크기를 예측하는 것은 혼합치열기 교정 진단과 치료계획 수립에 있어서 매우 중요하다. 미맹출된 견치와 소구치 크기를 예측하는 방법은 몇가지가 있지만 그중에서도 가장 흔하게 쓰이는 것이 모이어의 예측표와 다나카와 존스턴의 방정식이 있다. 하지만 그것들은 백인을 위해서 제작된 것이고 치아 크기는 인종에 따라서 다르다고 알려져 있다. 이번 연구에서는 치아크기를 측정하여 하악 영구 절치의 크기 합과 견치 및 소구치의 크기 합 사이의 상관관계를 구하고 회귀방정식을 이용해서 한국인에 맞는 예측표를 만들었다. 연세대학교 치과대학에 재학중인 178명의 한국 학생(남 108명, 여 70명, 평균연령 21.63)을 대상으로 실험하였다. 영구치의 근원심 폭경을 석고모형상에서 calipers를 이용해서 측정하였다. 성별간의 치아 크기는 차이가 있었다(p<0.05). Correlation coefficient는 0.57에서 0.64의 범위였고, standard errors of the estimates 는 여성에서 0.6으로써 남성보다 우수하였다. r^(2)값은 0.27에서 0.41의 범위를 나타내었다. Estimating the size of unerupted teeth is an essential aspect of orthodontic diagnosis and treatment planning in the mixed dentition. Several methods were introduced and used for the prediction. The most common methods among these would be Moyers probability chart and Tanaka and Johnston equations. These are currently used widely, but they were developed for Caucasians. Because there are clear racial differences in teeth size, the objectives of this study were to produce correlation coefficients between the combined mesiodistal widths of the permanent mandibular incisors and those of the canines and premolars for each quadrant, and prediction tables with regression equations, specifically for Korean. 178 young adults (70 women, 108 men, mean age 21.63 years) were selected from the College of Dentistry, Yonsei University, Seoul, Korea. The mesiodistal crown diameters of the permanent teeth were measured with calipers. Significant sexual dimorphism was found in tooth sizes. The correlation coefficients between the total mesiodistal width of the mandibular permanent incisors and those of the maxillary and mandibular canines and premolars were found to be between 0.52 and 0.64. The standard error of the estimatation was better (0.60) for women and the r^(2) values ranged from 0.27 to 0.41 for both sexes, Prediction tables were prepared for Korean. This study showed larger canine and premolar diameters than Tanaka and Johnston's and Moyers' studies which might be due to the racial differences. Further investigations with a larger sample size will be needed for more representative data on the Korean population.

      • KCI등재후보

        전경대원에서 발생한 결핵의 임상 양상

        문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

        Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

      • 부대동맥 림프절 또는 쇄골상부 림프절에 국한된 전이가 있는 재발성 자궁경부암 환자들의 예후에 관한 연구

        최석철,문형배 동국대학교 의학연구소 1998 東國醫學 Vol.5 No.-

        자궁경부암에서 림프절 전이가 병소의 재발이나 환자의 예후에 악영향을 미친다는 것은 주지의 사실이다. 그러나 자궁경부암으로 일차치료 후에 재발한 자궁경부암 환자들 중에서 부대동맥 및/혹은 쇄골상부 림프절에 전이가 있는 환자들의 임상적 특징 및 예후에 대해서는 잘 알려져 있지 않다. 따라서 본 연구는 자궁경부암으로 근치적 전자궁적출술 및 골반림프절 절제술이나 방사선치료 후에 재발한 환자들 중 부대동맥 및/혹은 쇄골상부 림프절에 전이가 있는 환자들의 임상적 특징 및 예후에 대해 알아보고자 하였다. 1991년 1월부터 1995년 12월 까지, 원자력병원 산부인과에서 자궁경부암으로 일차치료 후 전산화 단층촬영 및 세침흡인 세포검사에서 부대동맥 및/혹은 쇄골상부 림프절전이가 증명된 재발성 자궁경부암 환자 55명을 대상으로 하였다. 1. 대상환자 55례 중 부대동맥 림프절에 국한된 전이가 있었던 경우는 31례(56.4%)였으며, 쇄골상부 림프절에 전이가 있었던 경우는 24례(43.6%)였다. 쇄골상부 림프절에 전이가 있었던 24례 중 8례는 쇄골상부 림프절에 국한된 전이가 증명된 경우(Supraclavicnlar lynph node : SCLN only군)였고, 나머지 16례는 부대동맥 림프절 및 쇄골상부 림프절에 전이가 동시에 있는 경우(both군)였다. 2. FIGO 임상병기별 분포는 Ⅰ기 9.1%, Ⅱ기 56.4%, Ⅲ기 32.7%, Ⅳ기 1.8%였다. 세포형태에 따른 림프절 전이율은 편평상피세포형이 96%(53/55)였다. 대상환자 55례 중 22례(40.0%)는 일차치료 당시 이미 골반림프절에 전이가 있었던 경우였다. 대상 환자들의 원발암 치료는 방사선 치료만을 시행 받은 경우가 60.0%(33/55), 방사선 치료와 항암화학요법을 시행 받은 경우가 18.2%(10/55), 수술 및 방사선 치료, 항암화학요법을 시행 받은 경우가 18.2%(10/55), 그리고 수술 및 방사선 치료를 시행 받은 경우가 3.6%(2/ss)였다. 3. 전체 연구대상 환자 55례의 3년 생존율은 14.4%이었으며, 부대동맥 림프절전이군과 쇄골상부 림프절전이군의 3년 생존율은 각각 15.4%, 10.7%이었고, SCLN only군 및 both군의 3년 생존율은 각각 0%, 19.7% 이었다. 결론적으로, 쇄골상부 림프절 전이가 있는 환자는 부대동맥 림프절에 국한된 전이가 있는 환자보다 3년 생존율이 낮음을 알 수 있었으며, 이에 따라 재발성 자궁경부암 환자에서는 쇄골상부 림프절의 전이 유무가 환자의 예후를 추정하는데 중요한 지표가 될 것으로 생각되었다. It is evident from previous reports that in patients with cervical cancer with metastases to lymph nodes have unfavorable outcome, there are, however, few reports have previously been made of the clinical characteristics and prognosis of patients with metastasis limited to para-aortic lymph nodes(PALN) only versus supraclavicular lymph nodes(SCLN) following primary treatment. This paper attempts to discuss the outcome of Patients with recurrent cervical cancer metastasis limited to these lymph nodes. This report is a retrospective analysis of 55 patients with recurrent cervical cancer metastasis limited to para-aortic or supraclavicular lymph nodes following radical hysterectomy or definitive radiation therapy treated at the Korea Cancer Center Hospital, from January 1991 through December 1995. The results were as follows. 1. Of the 55 patients entered, 31(56.4%) had positive nodes on para-aortic area only and 24(46.3%) had positive nodes on supraclavicular area. 8 of 24 patients had limited metastasis to SCLN only and 16 had metastatic nodes on both para-aortic and supraclavicular area. 2. The distribution of patients according to initial FIGO stage were 9.1% in stage Ⅰ, 56.4% in stage Ⅱ, 32.7% in stage Ⅲ, and 1.8% in stage Ⅳ. In 96.4%(53/55) of cases, the histologic type was a squamous cell carcinoma. 22(40.0%) of 55 patients had pelvic lymph node metastasis at the time of initial treatment. The distribution of patients by treatment modalities prior to recurrence was 60.0%(33/55) for patients treated with radiotherapy alone, 18.2%(10/55) for patients treated with combined chemotherapy and radiotherapy, and 18.2%(10/55) for patients treated with combined surgery, radiotherapy, and chemotherapy. 3. The overall 3-year survival rate for patients with positive nodes on para-aortic or supraclavicular area was 14.4%; those who had lymph nodes limited to para-aortic only achieved 15.4%; those who had lymph nodes limited to supraclavicular lymph node achieved 10.7%. Of these, those who had nodes on supraclavicular lymph node only or both supraclavicular and para-aortic lymph node achieved 0% and 19.7% 3-year survival rate, respectively. In conclusion, the outcome for patients with metastasis to supraclavicular lymph nodes was worse than for patients with metastasis to para-aortic lymph nodes only. This suggest that the presence of metastatic carcinoma on supraclavicular lymph node may be a reliable Predictor of probability of survival in such patients.

      • 가막만에 분포하는 대형저서동물의 계절적 분포 및 출현

        최상덕,문성용,안치영,윤호섭,정형택,이삼노,서호영 國立 麗水大學校 환경문제硏究所 2001 環境硏究論文集 Vol.4 No.-

        This study was coducted to describe the distribution and appearance pattern of macrobenthos in Kamak Bay, the southern coastal of Korea. Sampling was perfound seasonally using Van Veen grab(0.1㎡) from April 2001 to December 2001. A total of 22 macrobenthic species occured: Bivalvia accounted for 12 species(55%), and Mollusca 5 species(23%). The mean density of macrobenthos was 153.9ind./㎡, a major dominant species were a Bivalvia, Paphia undulata(28.3ind./㎡), and a Cirripedia, Chthamalus challengeri(5ind./㎡), which frequency occur in the costral area. These species showed very low density at station 1 in the Kamak Bay.

      • KCI등재후보

        고체상 추출과 GC/MSD를 이용한 금속가공유중 다핵 방향족 탄화수소류 및 그 유도체의 분석

        최호춘,김강윤,안선희,문형중 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

        This study was performed to confirm an analytical method for polyunclear aromatic hydrocarbons (PAHs) in metalworking fluids(MWFs) which were used in metalworking factories. To ensure the analysis with accuracy and precision the fesults of PAHs in MMFs, this study was tried to use solid phase extraction(SPE) and gas chromatography/mass selective detector(GC/MSD). Also, this study was examined the concentrations of PAHs in MMF bulks and the qualitative analysis polycyclic aromatic compounds(PACs)excluding PAHs. 21 bulk samples were sampled in 7 metalworking factories. 21 bulk samples were 18 cutting oil(13 straight oils and 5 soluble oils) and 3 others(lubricating oil, discharge oil. compresses oil). 6 SPE cartridges were used to analyze PAH in MMFs and GC/MSD(satum 2000, Varian, U.S.A). Among the the 6 SPE cartridgesm this study was selected strong cation exchanger(SCX, aromatic benzene sulfonic acid functional group) cartridge for PAHs extraction in MMFs. Also the recovery test was performed. 1. The appropriated cartridge of SPE for analysis of PAHs in MWFs was found to be SCX. 2. The detected PAHs in MWFs were naphthalene(n=2). acenaphthylene(n=1). phenanthree(n=1), anthracene(n=2), fluoranthene(=7), pyrene(n=11) benzo[b]fluoranthene(n=1), chrysene(n=1), benzo[k]fluoranthene(n=1), benzo[k]fluoranthene(n=1).benzo[a]pyrene(n=1), dibenz[a,h]anthracene(n=2) and benzo[ghi] perylene(n=8). Total PAH(n=12) concentrations range were lower than LOD-270.03ug/ml. 3. The component of the PACs excluding PAHs were naphthalenes, acenaphthenes, chrysenes, anthracenes, indenes, fluoranthenes, fluorenes, pyrenes, benzopyrenes, phenantherenes and others volitile organic compounds(VOCs)were amines, phenols, aldehydes and others. For the results, SCX cartridge was better than other 5 SPE cartridges. 13 of 16 PAHs components were detected in MWFs. However recovry rate in this study should be improved analytical techniques on PAHs in MWFs. Also this study was need for further investigation for more MWFs samples and environmental monitoring and evaluation of MWFs exposed workers.

      • KCI등재

        Angiotensin Ⅱ로 유도된 혈관신생에 대한 日川芎의 억제효과

        文成一,金亨煥,趙貞姬,安德均,崔湖榮 대한본초학회 2002 大韓本草學會誌 Vol.17 No.2

        Objective : To estimate the angiogenic effect of water extract of Cnidii Rhizoma (ECR), we employed the rat sponge model for angiogenesis. Methods : It was based on subcutaneous implantation of sterile polyester sponges in the SD rat and we have characterized the dye method that incorporates 5% carmine red and 1% cresyl violet in 10% gelatin. vascularity index (V.I.) expressed as ㎍ dye/mg tissue. Subcutaneous implantation of sterile polyester sponges in SD rats enhanced the neovascularization over 14 days, as determined by measurements of relative sponge blood flow by a vascularity technique. The angiogenic response was verified by histological evaluation of vascularized sponges. Results : Daily oral administration of ECR (100 mg/kg for 14 days) produce no apparent effect on angiogenesis. The vasoconstrictor peptide, angiotensin Ⅱ (AⅡ), in daily doses of 100 nmol, caused an intense neovascularization but lower doses of AⅡ produced no apparent effect (1 nmol and 10 nmol). Co-administration of 100 nmol AⅡ and 100 mg/kg ECR p.o. depressed 100 nmol AⅡ-induced angiogenic effect. Conclusion : We have shown that p.o. daministration of 100 nmol AⅡ accelerated angiogenesis. Meanwhile, co-administration of 100 nmol AⅡ and 100 mg/kg ECR highly suppressed angiogenic property.

      • 植物凝集素 Dolichos lablab L. 및 고양이 赤血球에 의한 사람 血淸型에 關한 硏究

        崔衡鎭,文國鎭 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.1

        Phytagglutinins(PHAs) would be classified into pan(non-specific), type-specific, and race-specific according to the nature of agglutinating activity on red blood cells. Type-specific PHAs, so called lectins, have been contributed to the new classifications of human red blood cell types, i.e. Cl, Htr, DL, Vp etc. and these outcomes made it possible to confirm individualities more precisely in medicolegal field. Recently, as a new approach, human sera were classified into several types by their inhibiting properties to some PHAs, which showed panagglutinating activities on certain animal red blood cells. So the author tried to classify human sera in a new type by use of Dolichos lablab L. extract which acted as a panPHA on cat red blood cells and concluded as follows. 1. The human sera would be classified into two types. One had certain substance which inhibited agglutinating activities of Dolichos lablab L. on cat red blood cells and the other hadn't. 2. The former was 34% and the latter was 66% in frequency. 3. The results showed no constant relationships with other blood or serum types, such as ABO, CI, H, ab.C, CCI, Hp, DL and WDL etc. 4. This new grouping of human sera would be applicable for the new classification of bloodstains.

      • 鑄鐵材料의 Melt Treatment 및 Carbon Contents에 關한 硏究

        최익수,김성주,문형태,노무근 삼척대학교 산업과학기술연구소 2001 産業科學技術硏究論文集 Vol.6 No.1

        It is the purpose of this study to investigate the melt treatment and properties of cast iron by varifying the holding time after inoculation treatment and carbon contents. The main results obtained by investigating the microstructure and carbon contents are as follows : The number of graphite in cast iron decreases by increasing the holding time of melts after inoculation treatment, and the coarsening of graphite is achieved by increasing the length and thickness of graphite. As the carbon contents increase in cast iron, the shape and size of graphite in cast iron structure increase continuously.

      • 난소의 미성숙 기형종 1예

        최기욱,김흥곤,문형배 圓光大學校 醫科學硏究所 1994 圓光醫科學 Vol.10 No.1-2

        The immature teratoma is the third most commin germ cell tumor of the ovary. It contains a variable amount of immature tissue derived from the three germ cell layers-ectoderm, mesoderm and endoderm. Most commonly the immature elements are neural origin. With the usage of chemotherapy following appropriate surgery, prognosis for patient with malignant germ cell tumor was improved considerably. We had experienced a case of immature teratoma of ovary. We report the case with review of the concerned literatures.

      • KCI등재

        추적조사를 중심으로 한 腰椎間板脫出症에 대한 蜈蚣藥鍼의 臨床的 硏究

        최회강,소기숙,고강훈,박소영,김성남,이종덕,원경숙,문형철,김성철 大韓鍼灸學會 2003 대한침구의학회지 Vol.20 No.3

        Objective : This study is performed for the purpose of examining the efficacy of the scolopendrid(Scolopendra morsitans L) which has been to low back pain as a folk remedy. Methods & Results : Seventy patints with H.I.V.D. treated with the scolopendrid aquacupuncture and examined 4 tests; D.I.T.I., physical test, Oswestry disability index, and self-conscious pain rate were studied. And we follow up after discharge, we evaluated the present state and recovery period. Or we evaluated by herniated type and duration of onset. There was 58~97% of efficacy rate in each tests. Moreover, statistically valuable change in all 7D.I.T.I. points and in disability index and in self-conscious pain rate was showed. Conclusion : The scolopendrid aquacupuncture is possible to be effective terating the H.I.V.D patients. so we suggest the possibility using this new remedy to the H.I.V.D. patients.

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