[교단에서] 새 『국사』교과서로 가르쳐 보니

홍혜숙 내일을 여는 역사 2003 내일을 여는 역사 Vol.12 No.-

후천성결핍증 환자에서 보인 중추신경계 침범의 자기공명영상 소견 : 2예 보고

홍혜숙 대한영상의학회 1996 대한영상의학회지 Vol.35 No.4

Central nervous system (CNS) manifestations in acquired immunodeficiency syndrome (AIDS) patients are an earlyand common feature. The spectrum of AIDS-related CNS diseases are encephalitis caused by the humanimmunodeficiency virus(HIV) itself, opportunistic infection, infarct and malignancy. We experienced two cases ofCNS involvement in AIDS and they were serologically diagnosed as HIV encephalitis and CNS toxoplasmosis, respectively. In the case of the HIV encephalitis patient, brain MRI showed a non-enhancing lesion with highsignal intensity on T2WI and low signal on T1WI and there was no mass effect on the right frontal lobe, periventricular white matter, splenium of the corpus callosum or bilateral basal ganglia. In the other case of CNStoxoplasmosis, MR showed multiple nodular and rim enhanced mass lesions in the right basal ganglia, thalamus andperiventricular white matter, which were of low signal intensity on T1WI and of high intensity on T2WI. We thusreport the related MRI findings.

전자선전산화단층촬영을 이용한 가상대장경 : 바륨관장검사, 대장경검사 및 병리소견과의 비교

홍혜숙 대한영상의학회 1998 대한영상의학회지 Vol.39 No.1

Purpose : To perform virtual colonoscopy using electron beam tomography(EBT) in patients in whom a colonic mass was present, and to compare the results with those obtained using barium enema, colonoscopy and gross pathologic specimens. Materials and Methods : Ten patients in whom colonic masses were diagnosed by either barium enema or colonoscopy were involved in this study. There were nine cases of adenocarcinoma and one of tubulovillous adenoma. Using EBT preoperative abdominopelvic CT scans were performed. Axial scans were then three-dimensionally reconstructed to produce virtual colonoscopic images and were compared with barium enema, colonoscopy and gross pathologic specimens. Virtual colonoscopic images of the masses were classified as either 1) polypoid, 2) sessile, 3) fungating, or 4) annular constrictive. We also determined whether ulcers were present within the lesions and whether there was obstruction. Results : After virtual colonoscopy, two lesions were classified as polypoid, one as sessile, five as fungating and two as annular constrictive. Virtual colonoscopic images showed good correlation with the findings of barium enema, colonoscopy and gross pathologic specimens. Three of six ulcerative lesions were observed on colonoscopy; in seven adenocarcinomas with partial or total luminal obstruction, virtual colonoscopy visualized the colon beyond the obstructed sites. In one case, barium contrast failed to pass through the obstructed portion and in six cases, the colonoscope similarly failed. Conclusion : Virtual colonoscopies correlated well with barium enema, colonoscopy and gross patholoic specimens. They provide three dimensional images of colonic masses and are helpful for the evaluation of obstructive lesions.

정상인에서의 슬관절 굴곡과 신전시의 십자인대의 자기공명영상 : 예비적 연구

홍혜숙 대한영상의학회 1996 대한영상의학회지 Vol.35 No.2

Purpose : As a baseline study for clinical application, we investigated MRI findings of normal cruciateligaments in the knee being flexed as compared to those in the knee being extended. Materials and Methods : Sevenasymptomatic volunteers were studied. Knee MRI was performed with a 1.5 Tesla unit using a dual 3 inch coil. Inthe decubitus position, sagittal scanning was performed with the knee in extension, and subsequently, in flexion.We observed the shape and signal intensity of both cruciate ligaments, and measured the angles between the longaxis of the femur and ligaments, and the ligament dimensions in extension and flexion images. Results : As flexionand extension images were compared, cruciate ligaments differed both in their appearance and dimensions. Withflexion, joint space was widened, PCL became straightened and the signal intensity of ACL became homogeneously low; both cruciate ligaments became longer and thinner. These MRI findings were statistically significant except forthinning of PCL. Conclusion : MRI appearance and the dimensions of cruciate ligaments were different in the flexedknee as compared to those in the extended knee.

제2형 당뇨병환자에서 혈장 HDL-콜레스테롤 수준과 심혈관계질환 위험요인 분석

홍혜숙,박종숙,유한경,김화영 Korean Diabetes Association 2008 Korean diabetes journal Vol.32 No.3

연구배경: 이상지혈증은 심혈관질환의 주요한 위험 요인으로 특히 HDL-콜레스테롤의 농도를 정상수준으로 유지하는 것이 중요하다. 본 연구에서는 제2형 당뇨병환자에게서 혈장 HDL-콜레스테롤 농도에 따른 특성을 비교하여 보았다. 방법: 제2형 당뇨병환자 252명 (남자: 134명, 여자: 118명)을 대상으로 신체계측과 생화학적 검사, 식품섭취빈도 조사를 통한 식이조사를 통해 평가하였다. 결과: 대상자의 평균 연령은 60.2 ± 1.1세로 남녀 대상자 모두에게서 HDL-콜레스테롤 농도가 낮은 군과 정상군 간에 키, 체중, WHR, 체지방량, 체지방률, 제지방량, 근육량, 체질량지수에서 유의한 차이가 없었다. 남녀 모두 HDL-콜레스테롤이 낮은 군이 대조군보다 동맥경화지수가 유의적으로 높게 나타났다 (P < 0.001). 식이에서는 남자 대상자의 경우 HDL-콜레스테롤이 낮은 군에서 탄수화물 에너지 섭취비율이 대조군보다 유의적으로 높게 나타났고 (P < 0.05) 여자 대상자의 경우는 HDL-콜레스테롤이 낮은 군에서 항산화 영양소인 비타민 B1, 비타민 E의 섭취가 낮은 것으로 나타났다 (P < 0.05). 결론: 본 연구에서 HDL-콜레스테롤이 낮은 군의 동맥경화 지수가 높아 HDL-콜레스테롤은 당뇨병환자에서 심혈관계질환과 관련이 있음을 알 수 있었다. 특히 남자에서 HDL-콜레스테롤이 낮은 군의 탄수화물 섭취비율이 높고, 여자에서는 많은 영양소의 섭취가 부족함은 HDL-콜레스테롤 농도와 영양소 섭취와의 상관성을 말해 주는 것으로 사료된다. 그러므로 탄수화물의 섭취비율조절과 항산화영양소를 비롯한 균형된 식사 조절이 혈장 HDL-콜레스테롤 농도를 높이며 이는 당뇨병환자의 심혈관계질환 예방에 중요할 것으로 사료된다.

‘세계사’ 교육과정과 교과서 속의 민주주의

홍혜숙 역사교육연구소 2013 역사와교육 Vol.- No.8

청소년동반자가 지각한 상담과정에서의 알아차림 방해요소에 대한 개념도 연구

홍혜숙,왕은자 한국상담학회 2015 한국상담학회 학술대회 논문집 Vol.2015 No.8

신생아의 요 농축능에 관한 연구

홍혜숙,정용헌 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.1

A prospective study was done on the 70 normal newborns observed in the nursery of the Chung nam National University College of Medicine, to evaluate the renal function with relation of feeding time and amount during the period of 8 months from Jan. 1987 to to Aug. 1987 The results were as follows: Ninety-three % of subjects voided initially within 24 hours and 100% of them within 48 hours. The average time of initial voiding was 13.8±9.48 hours. The value of specific gravity and osmolality of the initial urine were 1.008±4.99 & 279.5 ±152.6mOsm/kg respectively and proportionally related. Urine & feeding amount during the 1st 24 hours were 43.5±32.3cc & 112±47.31cc respectively .and proportionally related. Initial feeding time was 8.5±3.39 hours and urine & feeding amount during the 1st 24 hours increased as the initial feeding time early began

외래간호서비스 개선을 통한 고객만족도 향상

홍혜숙,방순식,김민정,이남숙,신경숙,이선숙,박은진 한국의료QA학회 2005 가을학술대회 Vol.2005 No.2

제2형 당뇨병환자에서 혈장 HDL-콜레스테롤 수준과 심혈관계질환 위험요인 분석

홍혜숙,김화영,박종숙,유한경 대한당뇨병학회 2008 Diabetes and Metabolism Journal Vol.32 No.3

Background: Cardiovascular disease(CVD) is the major cause of death in type 2 diabetic patients. The purpose of this study was to investigate the characteristics of Korean type 2 diabetes mellitus(DM) patients according to plasma high density lipoprotein(HDL) cholesterol level and to document the effect of diet on HDL-cholesterol. Methods: The subjects were 252(male: 134, female: 118) Korean type 2 DM patients recruited from a general hospital's DM clinic and divided into low HDL-cholesterol group(male < 40 mg/dL, female < 50 mg/dL) and control group(male ≥ 40 mg/dL, female ≥ 50 mg/dL). Anthropometric and hematological variables and dietary intake were assessed by the groups. Results: The subject's mean age was 60.2 ± 1.1 years and duration of diabetes was 9.5 ± 1.0 years. Anthropometric measurements(body fat mass, % body fat, WHR, fat free mass, and muscle mass) and BMI were not significantly different between two groups. The male subjects with low HDL-cholesterolemia showed higher Atherogenic Index(AI, P < 0.001) and higher % carbohydrate from energy than control group(P < 0.01). The female subjects with low HDL-cholesterolemia showed higher AI(P < 0.001) and a tendency of higher triglyceride level and lower intake of energy, protein, lipid, vitamin B1 and vitamin E(P < 0.05) than control group.Conclusion: The subject with low HDL-cholesterolemia showed significantly higher AI. Male subject with low HDL-cholesterolemia consumed higher carbohydrate and female subject with low HDL-cholesterolemia showed lower intakes of many nutrients. This result suggests the importance of an adequate and balanced diet to manage type 2 DM patients to prevent CVD complications.(KOREAN DIABETES J 32:215-223, 2008)