치매환자에 대한 Indeloxazine hydrochloride의 임상효과

한상익,백인호,전태연,고효진,김용찬 최신의학사 1991 最新醫學 Vol.34 No.3

정신분열증 환자에서 시각유발전위 P100의 지표학적 뇌영상

한상익,박무현,백인호 대한신경정신의학회 1993 신경정신의학 Vol.32 No.5

PI00 is one of the most stable and consistent visual evoked potentials. This is closely linked with visual information processing which has been thought to be generated in the cortical area (calcarine area). It has been extensively evaluated in psychiatric reseach, and many investigators have been trying to seek the relation between visual information processing and psychopathology, and it’ s clinical significance. It is now possible to map the spatiotemporal evaluation and statistical results of VEP PI00 wave form using the topographic brain mapping system developed by computer graphics and electronic engineering. Recently, the topographic brain m apping of VEP PI00 has been applied to evaluate the disturbance of visual information process, particularly with regard to the topographic distribution of P100 in schizophrenics. However, the results have been inconsistent With these aspects in mind, this study was designed to evaluate not only the amplitude but also the topographic distribution of VEP P100 in schizophrenics, and to examine the availability of the characteristic findings of VEP PI00 mapping as one of the biological markers. The subjects were consisted of 40 Schizophrenics who had been admitted to Our Lady of Mercy Hospital and Catholic University Medical College from September, 1989 to A ugust 1992. They did not take any psychotrophic medications for more than 4 weeks. 42 normal controls also did not take any psychotrophic medications for more than 4 weeks. The results were as follows : 1) In schizophrenics the latency of V EP P100 was 102msec. Positive and negative m ax im um amplitudes of P100 was 4.65士 3.44|iV in O 2 and ᅳ 2.4 8士 2.02|iV in F 3, respectively. The amplitude of P100 showed negativity in frontal area and positivity in occiptial area, and showed symmetrical topographic distribution. 2) In normal controls, the latency of V E P P100 was 104msec. Positive and negative m ax im um amplitudes of P100 was 3.95± 2.42|iV in O 2 , and ᅳ 2.55± 2.03|iV in F 3 , repectively. The amplitude of P100 showed negativity in frontal area and positivity in occipital area showed symmetrical topographic distibution. 3) At th latency point VEP PI00 showed no differences of amplitude in entire cortex, and showed no differences of topographic distribution between the groups. 4) Spatiotemporal analysis of VEP PI00 showed similiar beginning and ending point in time, and showed simliar topographic distribution during entire PI00 process in both groups. In light of our findings, it seems likely that the visual information processing shown in schzophrenics’ optic pathway, visual cortex and other association area is not different from that shown in normal control

The Development and Selection of SSR Markers for Identification of Peanut (Arachis hypogaea L.) Varieties in Korea

한상익,배석복,하태정,이명희,장기창,서우덕,박금룡 한국육종학회 2011 한국육종학회지 Vol.43 No.2

The groundnut or cultivated peanut (Arachis hypogaea L.) in Korea consists of 36 domestic varieties which have been developed and registered as cultivars for the public during last 25 years. To screen and identify of Korean peanut varieties and genetic resources, we present a simple and reliable method. A methodology based on simple sequence repeat (SSR) markers developed and widely used for prominent gene identification and variety discrimination. For identification of those 36 Korean peanut varieties, 238 unique peanut SSR markers were selected from some previously reported results, synthesized and used for polymerase chain reaction (PCR). Data were taken through acryl amide gel electrophoresis and changed into proper formats for application of data mining analysis using Biomine (all-in-one functional genomics data mining program). Consequently, twelve SSR primers were investigated and revealed the differences between those 36 varieties. These primer pairs amplified 27 alleles with an average of 2.3 allele per primer pair. In addition, those results showed genetic relationship by classification method within 36 varieties. The approach described here could be applied to monitoring of our varieties and adapting to peanut breeding program.

알코올 금단 증후군

한상익,유태열 한국의학사 1985 診斷과治療 Vol.5 No.4

벼 부산물을 함유한 생분해성 육모폿트의 기계적 성질 및 분해 특성

한상익,강항원,변대우,장기창,서우덕,나지은,김준영,최경진 한국작물학회 2011 한국작물학회지 Vol.56 No.1

작물의 이식재배에 활용이 가능한 생분해성 육묘용 폿트의 개발과 이용가능성을 검토하고자 수행한 결과는 다음과 같다. 1. 천연물을 이용한 생분해가 가능한 폿트의 제조를 위해 벼 부산물인 왕겨와 쌀겨를 이용하여 생분해성 농자재로 육묘용 폿트를 제조하였다. 2. 생분해성 육묘용 폿트의 기계적인 특성은 기존 생분해성 폿트로 활용되고 있는 지피폿트와 비교해서 제품의 초기 강도는 강하고 토양중에 처리하였을 경우 시간이 지남에 따라 제품의 강도가 급속히 감소하는 특성을 보였다. 3. 토양중 분해율을 간접 측정한 방법에서 거의 분해가 일어나지 않은 지피폿트에 비해 생분해성 폿트의 경우 작은 조각으로 떨어져 나가서 6주가 경과하였을 경우 45% 이상이 10 mesh 이하의 작은 조각으로 분해됨을 관찰하였다. 4. 생분해성 필름에 대한 유해성분 용출시험에서 중금속들이 검출되지 않았고, 국내 친환경 인증 기준이 정하는 생분해성 수지의 함량기준에 충족하였다. 5. 작물을 이용한 토양중 작물생육과 더불어 판단한 실질 분해력 시험에서도 지피폿트에 비해 왕성한 분해력을 보여 일반 농업 현장에 적용이 가능할 것으로 사료된다. The bio-degradable transplanting pot containing rice by-product (rice-hull and rice-bran) were developed, and tested their ability for agronomic use. Rice by-products were crosslinked with biodegradable aliphatic ally aromatic copolyesters or urea resin for making transplanting pot. Mechanical properties and degradability of these pots were measured and compared to those of the Jiffy pot (commercially used bio-degradable pot). Mechanical strength was higher than that of Jippy pot, and bio-degradability was excellent under the actual field condition. In addition, the pot could be degraded within 3 months under the ground. Our result indicated bio-degradable pot containing rice by-products has a great potential for such agronomic use.

[PE-0022] 쓴맛이 없는 저탄닌이며 소화율과 장 건강 개선 효능이 있는 ‘노을찰’ 수수

한상익,최명은,김지영,이병원,추지호,송석보,안연주,정찬식 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

눈큰흑찰’의 가바(GABA) 함량 증진을 위한 이화학적 처리 효과

한상익,나지은,서경혜,박지영,서우덕,박동수,조준현,이종희,심은영,남민희 한국작물학회 2014 한국작물학회지 Vol.59 No.4

We assessed the GABA accumulation and othercomponents after the ‘Nunkeunhukchal (BGE)’, ‘Josanghukchal(BR)’, and ‘Ilmibyeo (IB)’ grain was soaked in water for24, 36, 48, 60, 72 and 96 hr. The results showed a continuousaccumulation of GABA in soaking treated brown rice ofBGE and IB. Among the treated hours, 72 hours of soakinghad the maximal accumulation of GABA (51.4 mg/100 g),amino acid, polyphenol and other components. The activitiesof glutamate decarboxylase (GAD) in brown rice and rice-branwere the same in BGE rice. However, the formation of GABAtreated with L-glutamate as substrate showed dramatic increaseof 354.6 (fourteen times higher than normal extraction) and726.4 mg/100 g in BGE rice and rice-bran, respectively. These results suggested that the soaking and extraction withL-glutamate buffer could be better methods for the harvestof increased GABA.

벼 부산물을 함유한 생분해성 필름의 기계적 성질 및 분해 특성

한상익,강항원,변대우,장기창,서우덕,나지은,김준영,최경진 한국작물학회 2011 한국작물학회지 Vol.56 No.2

작물의 멀칭재배에 활용이 가능한 생분해성 필름의 개발과 이용가능성을 검토하고자 수행한 결과는 다음과 같다. 1. 천연고분자를 이용한 생분해가 가능한 필름의 제조를 위해 벼 부산물인 왕겨와 쌀겨를 이용하여 생분해성 필름을 제조하였다. 2. 천연고분자를 이용하여 개발된 생분해성 필름의 기계적인 특성은 기존 멀칭필름과 비교해서 신장율은 낮으나 인장강도는 2배 이상 강함을 보였다. 그리고 파열점 비교에서도 멸칭필름은 뚜렷한 파열점이 존재하고 그 이후에는 같은 힘을 주어도 계속 늘어난 반면, 생분해성 필름은 서서히 늘어나며 점차 힘을 증가시켜야 늘어나는 특성을 보였다. 3. 생분해성 필름에 대한 유해성분 용출시험에서 중금속 들이 검출되지 않았고, 국내 친환경 인증 기준이 정하는 생분해성 수지의 함량기준에 충족하였다. 4. 작물을 이용한 토양 분해력 시험에서도 3 개월 이후에 서 대부분 분해됨을 보여 일반 농업 현장에 적용이 가능할 것으로 사료된다. This study was aimed to develop blend films by rice by-product (rice-hull and rice-bran) and bio-degradable materials. The rice by-product was firstly prepared from the pulverizing for making fine powder. Bio-degradable materials could be prepared by melting at high temperature. The mixture of the fine powder of rice by-product and melted bio-degradable materials was then blended and cast into films. The obtained films were investigated on their morphology, secondary structures and properties by using SEM, ICP and ASTM, respectively. Mechanical properties and degradability of these films were measured and compared to those of the PE films. Mechanical strength of bio-films was higher than that of PE films, however elongation ratio showed lower percent than that of PE film. In addition, bio-film could be degraded into fragments within 3 months under the field condition of normal upland crop cultivation. Bio-degradable mulching film indicated great potential for agronomic use as a new source of bio-degradable material.

行政 組織의 原理

韓相翼 建國大學校 1963 聯合學會誌 Vol.- No.1

수수 잡종강세 계통의 영양, 기능성 및 호화특성 연구

한상익,안연주,추지호,최명은,송석보,성정숙,김지영 한국국제농업개발학회 2020 한국국제농업개발학회 학술대회 Vol.2020 No.12