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보툴리눔 A 독소 테논낭하 주사가 가토 외안근에 미치는 영향
하병진,김용민,권현석,장윤희,한승한,주영광,박종운,임찬영 대한안과학회 2006 대한안과학회지 Vol.47 No.2
Purpose: Currently, when injecting botulinum a toxin into the extraocular muscle, EMG (Electromyography) is used for accurate location. In this study, we examined the effects of subtenon botulinum toxin injection without EMG guidance by quantifying the morphological changes of the extraocular muscle fibers in rabbits. Methods: Using 10 New Zealand white rabbits, 10 units of botulinum a toxin in 0.1 ml of normal saline was injected into the subtenon space of the superior rectus muscles, 5 mm from the muscle insertion in right eyes. As a control, 0.1 ml of normal saline was injected into the subtenon space of the superior rectus muscles in left eyes. At 3 weeks after injections, the bilateral superior rectus muscles of each rabbit were carefully dissected from the globe. Cross-sections of 5 ?m thickness were obtained at the site, 5 mm from the insertion of each superior rectus muscle. Sections were stained with Masson`s trichrome and observed by light microscopy. Using Image-Pro Plus software, the diameter of the orbital layer myofibers was measured and statistical analysis was done using the Kruskal-Wallis test. Results: The average diameter of the orbital layer fiber cells after botulinum toxin injection was 11.5±2.26 ?m at 3 weeks, whereas that of the control was 14.4±3.77 ?m. The difference was statistically significant (p<0.01). Conclusions: The diameter of myofibers in the orbital layer was reduced after subtenon botulinum a toxin injection. Further studies on the duration of botulium toxin in subtenon space and the change in the size of myofibers depending on the dosage of botulinum toxin will be necessary.
하병진,김대홍,주영광,이은석,홍영재,Byoung-Jin Ha,Dae-Hong Kim,Young-Kwang Chu,Eun-Suk Lee,Young-Jae Hong 대한안과학회 2005 대한안과학회지 Vol.46 No.10
Purpose: Perimetric examination plays an important role in the diagnosis of glaucoma, which is among the leading causes of blindness worldwide. Several examination methods have been developed for early detection of glaucoma. Among those, short-wavelength automated perimetry (SWAP) is the most widely investigated. In this study, the effects of nuclear opacities on SWAP were examined. Methods: Lens opacities were divided into cortical and nuclear opacity groups ; each group consisted of fifteen eyes. The eyes studied underwent standard white-on-white perimetry and SWAP exams before and after cataract operation. The differences in the results of the examinations were compared between the two opacity groups. The t test was used for comparing the data. Results: In the cortical opacity group, the average difference between the mean deviation before and after the operation was 5.46dB in white-on-white perimetry and 5.02dB in SWAP. In the nuclear opacity group, the average difference between the mean deviation before and after the operation was 4.01dB in white-on-white perimetry and 10.82dB in SWAP. There was no statistically significant difference in the cortical opacity group (p=0.6575). However, there was a statistically significant difference in the nuclear opacity group (p<0.0001). Conclusions: In clinical situations, more caution should be taken when interpreting the SWAP results of nuclear cataract patients in order to make an accurate decision.
하병진 중국어문학연구회 2019 중국어문학논집 Vol.0 No.117
The purpose of this paper is to find the best edition among all editions of HeboshiBeilun(何博士備論). The study on edition is the basic work for further study. It was widely known that Xueyanzhai edition is the Best and the Oldest edition among the present editions until now. But according to our research, It couldn't say the best edition. Because just they couldn't find different point about missprints, usage of special word forms and content. In this paper, it will be attempted to find the best edition from a comparative between all edition of HeboshiBeilun.
하병진,이종민,윤선진,김병관,이준석,이수훈,류승재,차용엽,황성택,우동기,이창규,신동아,하윤,구성욱,김긍년,손동욱,이성 대한척추신경외과학회 2023 Neurospine Vol.20 No.3
Objective: The objective of this study was to evaluate the accuracy of pedicle screw placement in patients undergoing percutaneous pedicle screw fixation with robotic guidance, using a newly developed 3-dimensional quantitative measurement system. The study also aimed to assess the clinical feasibility of the robotic system in the field of spinal surgery. Methods: A total of 113 patients underwent pedicle screw insertion using the CUVIS-spine pedicle screw guide system (CUREXO Inc.). Intraoperative O-arm images were obtained, and screw insertion pathways were planned accordingly. Image registration was performed using paired-point registration and iterative closest point methods. The accuracy of the robotic-guided pedicle screw insertion was assessed using 3-dimensional offset calculation and the Gertzbein-Robbins system (GRS). Results: A total of 448 screws were inserted in the 113 patients. The image registration success rate was 95.16%. The average error of entry offset was 2.86 mm, target offset was 2.48 mm, depth offset was 1.99 mm, and angular offset was 3.07°. According to the GRS grading system, 88.39% of the screws were classified as grade A, 9.60% as grade B, 1.56% as grade C, 0.22% as grade D, and 0.22% as grade E. Clinically acceptable screws (GRS grade A or B) accounted for 97.54% of the total, with no reported neurologic complications. Conclusion: Our study demonstrated that pedicle screw insertion using the novel robot-assisted navigation method is both accurate and safe. Further prospective studies are necessary to explore the potential benefits of this robot-assisted technique in comparison to conventional approaches.