Dihydroxyaluminium Allantoinate(Altima�)의 消化性潰瘍 및 胃炎에 對한 臨床經驗

崔浩燮,鄭俊謨,鄭克守 中央醫學社 1976 中央醫學 Vol.30 No.3

Methoene blue 溶液의 會合에 관한 熱力學的 硏究

崔虎燮 群山大學校基礎科學硏究所 1992 基礎科學硏究 Vol.7 No.-

The study of optical properties(absorption and emission) of methylene-blue(MB) is an important research because these substances are often used an active or dye lasers.?? The behavior of methylene blue in aqueous solution has been investigated by means of absorption spectroscopy. When two or more methylene blue molecules in solution are separated intermolecular distance, their xanthene rings can interact electrostatically to form aggregates such as dimers, trimers, etc. The formation of these aggregates depends on many factors such as the molecular structure of the dye, concentration, PH of medium, solvent nature and temperature. Since the monomer and the dimmer form of methylene blue present different absorption properties, the visible absorption, the visible absorption technique is the standard one to follow the methylene blue dimerization process. These experimental procedure also provides us with a good way to research the thermodynamic parameters of the aggregation, permitting the discussion of the association forces.

The Effect of Comonomer Composition on Mechacnical Properties of Syndiotactic Poly(styrene-co-ethylene)

최호섭,양재식,조원호 한국고분자학회 2000 한국고분자학회 학술대회 연구논문 초록집 Vol.2000 No.4

아메바性 肝膿瘍에 關한 臨床的 硏究

崔浩燮,鄭克守 慶北大學校 醫科大學 1976 慶北醫大誌 Vol.17 No.1

1961年 1月부터 1975年 12月까지 滿 15年間 大邱市所在 2大綜合病院 卽 慶北醫大附屬病院, 東山基督病院 및 Fatima病院에 入院加療한 아메바性肝膿瘍總 474例에 대하여 그 臨床像 豫後 및 膿瘍의 治癒過程등에 관해 調査해 본 結果 그 主要成績은 다음과 같다. 1. 年齡層은 30∼40代가 大部分으로 約 60%를 차지하였고 男女比는 5.8 : 1이었다. 2. 都市와 農漁村別比는 1 : 2.2로 農漁村居住者가 많았다. 3. 上記 3大綜合病院內科 및 外科에 入院한 總患者數에 대한 아메바성肝膿瘍患者數의 比를 年度別로 보면 近年에 顯著한 減少를 나타내고 있었다. 4. 過去에 아메바性痢病로 생각되는 病歷을 가진 例는 29.5%이었고 便檢査에서 Entameba histoltica陽性인 例는 21.9%이었다. 5. 初診時 아메바性肝膿瘍以外의 診斷名을 받은 例가 約 30%에 達했는 바 이들중 으뜸은 단도질환(11.4%)이었고 다음이 肝癌(6.1%)이었다. 6. 治療方法으로는 抗아메바劑와 肝穿剌등 內科的治療를 原則으로 하였는 바 71.3%에서 1∼5回, 21.5%에서 6∼10回 穿剌가 施行되었으며 20回以上 穿剌된 例가 1例(0.3%)있었고 平均 4.6回穿剌가 施行되었다. 7. 合倂症으로서 膿瘍의 混合感染이 19.4%에서 볼 수 있었고, 肺肋膜合倂症(12.9%)을 包含한 其他合倂症이 18.6%에서 볼 수 있었다. 8. 治療에 依해 熱이 下降하기 始作한 時期와 正常體溫恢復時期는 各各 平均 4.8 및 7.5日이었다. 9. 同位元素를 利用한 肝走査 및 nitroimidazole系藥劑가 使用되기 始作한 時期를 境界로 해서 그 以前과 以後의 治療豫後를 보면 以後가 良好하였다. 10. 肝走査가 施行된 以後에 있어서 chloroquine을 主로 한 在來式治療方法(A群)과 여기에 nitroimidazole을 倂用한 方法(B群)을 使用한 境遇의 豫後를 보면 B群에서 良好하였다. 11. 解熱은 A 및 B群사이에 有意義한 差가 없었으나 膿瘍의 大中小크기別로 보면 크기가 작은群에서 빨랐다. 12. 肝走査에 依해 肝膿瘍의 縮小過程을 追究해 보면 全體的으로 보아 膿瘍의 消失은 4週以後에 비로소 볼 수 있었으며 治療方法 B群에서 若干 成績이 優秀하였다. 그러나 4週以內의 治療速度는 A 및 B群間에 뚜렷한 差異를 볼 수 없었다. 13. 肝膿瘍의 大中小크기別로 그 縮小經過를 보면 크기에 따른 一定한 傾向은 볼 수 없었다. 14. 結局 治療經過를 綜合해서 보면 解熱等 臨床症狀은 比較的 數日이라는 短時日內에 恢復하나 膿瘍의 治癒消失은 徐徐히 이루어져 1乃至 數個月 要하는 것으로 보이며 臨床所見好轉速度와 膿瘍의 治癒速度와는 반드시 平行하지는 않은 것 같았다. Four hundred and seventy-four cases of amebic liver abscess admitted to the three major general hospitals in Daegu City, Korea (Kyungpook National University Hospital, Dongsan Presbyterian Hospital and Fatima Hospital) during the past 15 years from 1961 to 1975 were surveyed on various clinical aspects. In addition, serial hepatoscans with ^198Au for 44 cases were done in an attempt to determine the resolution time for the amebic liver abscesses by different modality of treatment. Group A(total 25 cases) was treated with chloroquine orally 1,0 gm on day 1 and 2 and 0.5 gm daily thereafter for 19 days along with oxytetracycline 2.0 gm per day in 4 divided doses for 10 days, while group B(total 19 cases) was treated with additional nitroimidazole derivatives(metronidazole 1,800 ㎎ per day in 3 divided doses for 5-10 days or tinidazole 600㎎ per day in 4 divided does for 5-10 days). Emetin hydrochloride was seldom used except for severe cases (0.065㎎ parenterally for 5-7 days). Needle aspirations of pus were routinely combined with the above medication. The size of the abscess was measured on scan film and was grouped into 3 graded sizes i, e large(over 15㎝ in diameter), moderate (10-15 ㎝ in diameter) and small (less than 10 ㎝ in diameter). The results obtained were as follows: 1. About 60% of cases belonged to the age groups of 4th and 5th decades and male to female ratio was 5.8:1. Residents in rural districts were greater in number by 2.2 times of urban residents. The yearly incidence of cases among total in-patients of department of Internal Medicine and General Surgery has decreased recently from around 0.7% down to 0.4%. 2. Biliary tract disease was the initial diagnosis of 11.4% and hepatoma 6.1%. 3. Mean days for the body temperature begin to fall and return to normal were 4.8 and 7.5 days respectively. And drop in fever was faster in smaller size group but did not show significant difference in rapidity between group A and B. 4. Prognosis was improved since 1970 when liver scan and nitroimidazole derivatives were available. And prognosis of group B was better than that of group A both treated during the same period of 1970-1975. 5. Healing of abscess was seen after 4 weeks of treatment and numbers of healed cases were greater in group B. However, the rate of reduction in size of abscess during the 4 weeks after the initiation of treatment showed no difference between group A and B and also it had poor correlation with the grading of abscess size.

稀薄溶液에서 有機色素分子와 陰이온 界面活性劑사이의 會合에 관한 效果

崔虎燮 群山大學校自然科學硏究所 1988 自然科學硏究 Vol.3 No.-

The metachromatic behavior leading to the formation of aggregation between organic dyestuffs and anionic surfactants was investigated spectroscopically by varying the concentration with the addition sufactants. The appearance of a new band(meta-band) is explained as a high aggregation of organic dye molecular at a range 300 through 400 S/D value in dye-surfactant complex system. The deminishing of a meta-band at the above 700 of S/D value due to attribute to redistribution and the formation of micelle by the drim.

대규모 우리말 어휘지능망 구축 방법

최호섭,임지희,옥철영,김정우 한글학회 2006 한글 Vol.- No.273

This research presents the construction principles of Urimal-Word Intelligent Network(U-WIN) based on Korean Dictionary and Corpus for Korean Language. Through the R&D method for construction of U-WIN, this research examines essential particulars of the lexical network like inner structure systems of the lexical network, a collection of basic vocabulary, a system of lexical notation, a processing for homograph and polysemy, and so on. And also this research examines that morphological․syntactical․semantic․NLP(natural language processing) research methods is how to be reflected in lexical network, through U-WIN that consists of structure systems like lexical network, ontology, thesaurus. 이 연구는 한국어를 대상으로 2002년부터 시작되어 현재까지 진행되고 있는, 국어사전을 기반으로 한 우리말 어휘지능망인 유윈(U-WIN)의 구축 원리를 제시한다. 그리하여 유윈 구축을 위한 연구 개발 방법을 통해 도출된, 기초적인 내부 구성 체계를 중심으로 기초 어휘 선정, 어휘 표기 방법, 동형이의어 및 다의어 처리 방법 등 어휘망의 고려 사항을 살펴보고, 나아가 형태론적․통사론적․의미론적․언어처리적 측면의 이론적 연구 결과가 어떻게 어휘망에 반영되는지를 살펴보고자 한다.

The effect of sequence distribution on pH-dependent conformational change of amphipathic polypeptides

최호섭,허준,조원호 한국고분자학회 2004 한국고분자학회 학술대회 연구논문 초록집 Vol.2004 No.04

유기색소 분자와 음이온 계면활성제 및 고분자 전해질 사이의 효과에 관한 흡수 분광학적 연구

崔虎燮 群山大學校自然科學硏究所 1990 自然科學硏究 Vol.5 No.-

The metachromatic behavior of methylene blue(MB) and rhodamine-6G(Rh-6G) in aqueous solution and in the presence of sodium dodecyl sulfate(SDS) and bis(2-ethyl-hexyl) sodium sulfosuccinate; Aerosol OT(AOT) has been investigated by means of absorption spectroscopy. In the presence anionic surfactants, the characteristic change of the spectra of both MB and Rh-6G with the change of S/D (〔surfactant〕/〔Dye〕) value have been observed. The new bands appeared at shorter wavelength region than that of the β-band of the both dyes at S/D range of 300∼400 are assigned to be behavior is quite similar to that of the well known meta-band of dye-polymer system. The critical micelle concentrations(cmc) of both aqueous solution of surfactants alone and those of dye-surfactant systems are measured by the use of electrical conductivity method. The cmc values are found 3.9mM, and 2.8mM for MB-SDS, MB-AOT and Rh-6G systems, respectively. These Values are found to be lower than those of the aqueous solution of SDS and AOT alone, i. e, 8.2mM and 4.5mM, respectively. These facts are ascribed to the formation of dye-rich induced micelles(drim). The raction schemes of five steps are proposed for the porcess of the process of the dye-surfactant interaction throughout the range of surfactant concentraction. These schematic are found to be reasonable in the explanation of the spectral behavior of the dye-surfactant system.

Proflavine과 Coriphosphine(cp)의 誘導體들에 대한 光學的 吸收Spectra에 관한 硏究

崔虎燮 群山大學校 1984 論文集 Vol.7 No.-

The optical absorption spectra of several derivatives of proflavine(PF) and coriphosphine (CP) were measured in agueous solution at 25c. The effect of the perturbation of one both of the exonuclear amino groups on the spectral behavior was studied in order to explore the relationship between the spectra and the chemical structures of the symmetric 3.6-disubstituted acridine dyes which can bind to various polyelectrolytes, often showing metachromasy. The metachromatic spectra of the complexes between 3.6-diaminoacridine dyes and polyanions were reproduced reasonably well when one of the two groups of PF was converted to an acylamino group. A similar result was observed when the amino group of CP was acetylated. In these cases, the spectra show two absorption bands of nearly equal intensity on both sides of the single peak of PF and CP in the visible region. These results are indicative of the close similarity in chemical structures between the monoacylamino PF and the PF bound to the electron-rich sites of polyanions.

아메바性 肝膿瘍에 關한 臨床的 硏究

崔浩燮,鄭克守 慶北大學校 醫科大學 1976 慶北醫大雜誌 Vol.17 No.1