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전성주(Seoung Ju Chun),전정수(Jung Su Chun),김재하(Jae Ha Kim),최두혁(Do Hyok Choi) 대한내과학회 1987 대한내과학회지 Vol.33 No.5
N/A Korean hemorrhagic fever which was recognized for the first time in Korea near the Demilitarized Zone between North and South Korea in 1951 during Korea War have spread to the southern part of the Korean peninsula and several hundreds of cases are clinically and serologically diagnosed each year. However the Northern Part of Kyoung Ki Do is still remained as epidemic area. In recent years, we experienced 55 cases of Korean Hemorrhagic Fever in the northern part of Kyoung Ki Do during the period, 1984-1986, and we found different clinical patterns of Korean hemorrhagic fever from those reported earlier. Here we report the epidemiological and clinical observations with laboratory findings. 1) The disease was prevalent in adult male farmers and the epidemic seasons were fall and early winter. The epidemic areas of the disease are mainly Yang Ju, Yeoncheon and Pocheon. 2) Clinical pictures of Korean Hemorrhagic Fever were characterized by headache (76%), abdominal pain (69%), nausea & vomiting (67%), fever (56%) and myalgia & general aching (49%). 3) On physical examination, fever (56%), abdominal tenderness (36%), tachycardia (35%), hypotension (27%), petechia (24%), conjunctival injection (22%) and facial flushing and edema (16%) were found. 4) On laboratory examination, leukocytosis, thrombocytopenia, left shift of leukocyte, toxic granule, proteinuria, microscopic hematuria and increased specific gravity were found. Blood chemistry findings were characterized by increased BUN & creatinine, increased SGOT & SGPT, hyponatremia, increased LDH & FDP and hyperkalemia. 5) Clinical forms of typical hemorrhagic fever were as follows: Typical oliguric type 49%, typical nonoliguric type 21% and atypical type 29%. 6) Double infection to Leptospirosia was found in 8 cases.
혈청학적으로 진단된 1986 년도 Rickettsia 질환의 발생 양상
김선영(Sun Young Kim),장우현(Woo Hyun Chang),강재승(Jae Seung Kang),최명식(Myung Sik Choi),최인학(In Hak Choi),박경희(Kyung Hee Park),김석용(Suk Yong Kim),최강원(Kang Won Choe),최두혁(Do Hyok Choi),김우열(Woo Yeol Kim),이증훈(Jeung H 대한내과학회 1987 대한내과학회지 Vol.33 No.5
N/A From early spring 1986 to 1987, serum specimens from 1141 individuals with acute febrile episodes were collected from 9 local collaborators and tested for antibodies to R. tsutsugamushi and R. typhi by indirect immunofluorescent antibody test. 1) Of these, 353 sera (31%) showed positive reaction to R. tsutsugamushi and 115 sera (10%) showed positive reaction to R. typhi. 2) R. tsutsugamushi and R. typhi infections are seemed to occur throughout the country in Korea. The highest positive rate was shown in Chollanamdo. 3) Tsutsugamushi disease and Typhus group rickettsial disease were the most prevalent in October, and November. 4) 132 sera (12%) and 129 sera (11%) among 1141 individuals gave positive reaction to Leptospira and Hantaan virus respectively.