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자궁경부 편평상피병변에서 자궁경부질도말 세포검사의 진단정확도 : 481예의 세포-조직 상관관계
진소영,박상모,김미선,진윤미,김동원,이동화,Jin, So-Young,Park, Sang-Mo,Kim, Mee-Sun,Jeen, Yoon-Mi,Kim, Dong-Won,Lee, Dong-Wha 대한세포병리학회 2008 대한세포병리학회지 Vol.19 No.2
Background : Cervicovaginal cytology is a screening test of uterine cervical cancer. The sensitivity of cervicovaginal cytology is less than 50%, but studies of cytologic/histologic correlation are limited. We analyzed the diagnostic accuracy of cervicovaginal cytology in the detection of the squamous epithelial lesions of the uterine cervix and investigate the cause of diagnostic discordance. Materials and Methods : We collected a total of 481 sets of cervicovaginal cytology and biopsies over 5 years. The cytologic diagnoses were categorized based on The Bethesda System and the histologic diagnoses were classified as negative, flat condyloma, cervical intraepithelial neoplasia (CIN) I, CIN II, CIN III, or squamous cell carcinoma. Cytohistologic discrepancies were reviewed. Results: The concordance rate between the cytological and the histological diagnosis was 79.0%. The sensitivity and specificity of cervicovaginal cytology were 80.6% and 92.6%, respectively. Its positive predictive value and negative predictive value were 93.7% and 77.7%, respectively. The false negative rate was 19.4%. Among 54 false negative cytology cases, they were confirmed by histology as 50 flat condylomas, 2 CIN I, 1 CIN III, and 1 squamous cell carcinoma. The causes of false negative cytology were sampling errors in 75.6% and interpretation errors in 24.4%. The false positive rate was 7.4%. Among 15 false positive cytology cases, they were confirmed by histology as 12 atypical squamous cells of undetermined significance (ASCUS) and 3 low grade squamous intraepithelial lesions (LSIL). The cause of error was interpretation error in all cases. The overall diagnostic accuracy of cervicovaginal cytology was 85.7%. Conclusions : Cervicovaginal cytology shows high overall diagnostic accuracy and is a useful primary screen of uterine cervical cancer.
진소영,Jin, So-Young 대한세포병리학회 2008 대한세포병리학회지 Vol.19 No.2
Cerebrospinal fluid (CSF) cytology is based on the cytopathologic findings of other body fluids. However, CSF's cytologic features are less familiar to physicians than are those of the other body fluid's cytology because of the small number of cases. The low overall diagnostic accuracy and the presence of false positivity still remain as problems. The incidence of lymphoreticular malignancies and metastatic carcinomas are rather higher than that of primary brain tumors. In this review, the characteristic cytologic findings of conventional CSF cytology are reviewed along with a brief note on the technical preparation and diagnostic pitfalls.
유방의 아포크린 암종의 세침흡인 세포학적 소견 - 2예 보고 -
진소영,이동화,곽정자,Jin, So-Young,Lee, Dong-Wha,Kwak, Jeong-Ja 대한세포병리학회 1992 대한세포병리학회지 Vol.3 No.2
Apocrine carcinoma is a rare form of breast malignancy and is composed of entirely or predominantly of apocrine type epithelial cells. Apocrine metaplastic cells are frequently noted in fine needle aspiration cytology(FNAC) of breast lesions, especially fibrocystic disease. These apocrine cells may occasionally be atypical, to make a diagnostic difficulty. Two cases of apocrine carcinoma of the breast diagnosed by FNAC are described, and differential cytologic points between apocrine metaplasia and apocrine carcinoma are discussed. The first case is a right breast mass of a 37-year-old woman for 20 days. The smears show many single or sheets of large cells on bloody background. Each cell has a large vesicular nuclei with multiple macronucleoli and abundant eosinophilic granular cytoplasm. The second case is a left breast mass of a 35-year-old woman for one month. The smears show similar findings as seen in the first one. Histopathologic findings of both cases are typical of apocrine carcinoma. Electron microscopy demonstrates variable numbers of large osmiophilic granules in diameter of $200\sim600nm$ in both cases.
진소영 ( So Young Jin ) 대한간학회 2013 Postgraduate Courses (PG) Vol.2013 No.-
Nonalcoholic fatty liver disease (NAFLD) cannot be differentiated from alcoholic fatty liver disease without history of alcohol ingestion. Their histologic findings overlap those of alcoholic liver disease in most cases. Nonetheless, liver biopsy is the golden standard for confirmative diagnosis of nonalcoholic steatohepatitis (NASH) and estimation of fibrosis in fatty liver disease. Through “NAS (NAFLD activity score)” has been developed based on the key features of NASH; steatosis, lobular inflammation and ballooning degeneration, its score itself cannot be used as a diagnostic criteria. Characteristic pathologic findings of NASH, current grading and staging system, and differential diagnosis from alcoholic steatohepatitis will be discussed.
진소영 ( So Young Jin ) 대한내과학회 2011 대한내과학회지 Vol.80 No.4
Pancreas is an endocrine organ as well as an exocrine one. The pancreatic neuroendocrine tumor (PNET) is an epithelial tumor with features of endocrine differentiation. Its incidence is progressively increasing now. Because the prognosis of PNET is much better than that of ductal adenocarcinoma, the precise diagnosis and proper treatment is more important than ever. Recently World Health Organization (WHO) and American Joint Committee on Cancer (AJCC) published the new WHO 2010 classification and the unified staging system of the PNET unlike the other gastrointestinal tract. Here, recent update of pathology of PNET will be discussed with their basic morphologic characteristics and essential points in the pathology report. (Korean J Med 2011;80: 371-377)
진소영(Jin, So-Young),김세환(Kim, She-Whan) 한국체육과학회 2018 한국체육과학회지 Vol.27 No.3
A new syndrome named Normal Weight Obesity (NWO) has attracted much attention in obesity-related researches. NWO i s a normal B ody Mass I ndex (BMI) a ssociated with a l arge p roportion of % Body Fat(%BF). Previously, NWO was known as a problem associated with aging. However, recent years, it has appeared to many young women. Lookism is the largest cause. Lookism has been shown to spread in our society, excessive diet and irregulareating habits, was supposed to lead to results, such as body weight regulation of in an unusual way. The purpose of this study was to find the prevalence of NWO, and the eating and exercise behaviors of Korean university women. We studied 422 volunteers, 138 were interviewed. 140 university women had bioelectrical impedance analysis to estimate body composition. All the participants filled out the Questionnaire that eating and exercise behavior. The percentage of Standard was 48.6%, NWO was 32.0% and Obesity is 10%. Interestingly, significant differences between Standard and NOW in exercise behaviors (p<.001). But, there were no significantly different in eating behaviors (p<.001). In contrast, both of eating and exercise behaviors were significantly different between Standard and Obesity (p<.01). As expected, NWO and Obesity were significant differences eating Behavior only (p<.05). The findings of the study represent important directions for the future planning of intervention programs designed to prevent NWO. Exercise interventions are warranted to prevent NWO in university women.