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벤처 재도약’릴레이 기고문(4)-2만불시대를 열어갈 '벤처기업 주도의 인력 양성'필요
조현정,Jo, Hyeon-Jeong 벤처기업협회 2004 벤처다이제스트 Vol.62 No.-
지금 우리는 청년실업자수가 연일 최대치를 기록하는 시대에 살고 있다. 청년실업은 심각한 사회문제인 동시에 2만불시대를 열어갈 걸림돌로 작용될 수 있다는 것이 전문가들의 의견이다. 이에 청년실업자들에게 필요한 것은 무엇이고, 우리 벤처기업이 그들을 위해 해줄 몫은 무엇인지 비트컴퓨터 조현정 대표에게 들어보았다.
파노라마방사선사진 지수와 임플란트 실패와의 관계에 관한 연구
조현정,이원진,허민석,안창현,이진구,이삼선,최순철 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1
Purpose : Several panoramic indices have been suggested to assess bone quality from the morphology and width of mandibular cortex on panoramic radiography. The purpose of this study was to compare dental implant failure group with control group in panoramic mandibular index (PMI), mandibular cortical index (MCI), and gonion index (GI) and to determine the effect of these panoramic indices on dental implant failure. Materials and Methods : A case-control study was designed. Test group (n = 42) consisted of the patients who had their implants extracted because of peri-implantitis. Control group (n = 139) consisted of the patients who retained their implants over one year without any pathologic changes and had been followed up periodically. They had dental implants installed in their mandibles without bone augmentation surgery from 1991 to 2001. The following measures were collected for each patients: 1) PMI, MCI, and GI were measured twice at one-week interval on preoperative panoramic views; and 2) age, sex, implant length, implant type, installed location, occluding dentition state, and complication were investigated from the chart record. Results : The PMI showed moderate level of repeatability. The intra-observer agreement of MCI and GI were good. There was statistically significant difference in PMI between two groups. There were significant different patterns of distribution of MCI and GI between two groups. Among the panoramic indices, PMI and MCI showed significant correlation with dental implant failure. Conclusion : Panoramic indices can be used as reference data in estimating bone quality of edentulous patients who are to have implants installed in their mandibles.
γ-PGA에 포함된 D-glutamate의 효소화학적 정량분석
조현정,지광환 금오공과대학교 2005 論文集 Vol.26 No.-
Bacillus subtilis chungkookjang produces a new biofunctional polymer, poly y-glutamic acid (γ-PGA). γ-PGA consists of D and/or L-glutamate and its ratio is different depending microorganisms and culturing environrrents, Here we are reporting the new enzymatic method to determine the stereochemistry of D-glutamic acid composition ratio in γ-PGA D-amino acid aminotransferase (D-AAT) can catalyzes transamination between D-amino acids and a-keto acids. Thus the amount of D-glutamate in γ-PGA can be determined by the assaying the amount of produced D-alanine followed by the reaction of D-AAT in the presence of pyruvic acid. D-glutamate and D-alanine can be separated by thin layer chromatography (TLC) in NH₄0H : ethanol (2:8, v/v) solvent system D-alanine can be visualized by ninhydrin (0.5% in 75% ethanol) spraying and quantitated by the measurement the absorbance of TLC spot followed by the elution with 0.005% copper sulfate in 75% ethanol at EOOnm. Partially purified D-AAT is good enough to carry out this new and very convenient method to determine the amount of D-glutamic acid in γ-PGA.
가임력 보존을 위해 시행된 항암화학요법에 저항성을 보인 태반부착부위 영양막종양 1예
조현정,곽현성,남선영,강영화,김민정,임현욱,이희정,김사진,허수영 대한부인종양학회 2007 Journal of Gynecologic Oncology Vol.18 No.4
Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic tumor (GTT) that has different behavior in disease process. The hysterectomy is general for PSTT, but hysterectomy is undesirable for patients who wish to remain fertile. We planned to preserve fertility of a young patient by first administering EMA/CO (Etoposide, methotrexate, actinomycin D/cyclophosphamide, vincristine) chemotherapy and then performing an open uterine surgery to remove residual tumor. The patient who attempted primary chemotherapy for PSTT must be undergone a hysterectomy because this conservative regimen showed sign of chemoresistance. We report a case of chemoresistant PSTT with trial to preserve fertility with a brief review of literatures. 태반부착부위 영양막종양은 일반적인 임신성 영양막종양과는 다른 질병 진행 과정을 보이는 드문 유형이다. 자궁절제술이 일반적인 치료이지만, 가임력의 유지를 위하여 자궁을 보존하기를 원하는 경우에는 일차적 치료로서 자궁절제술을 시행 할 수 없다. 최근 저자들은 가임력의 유지를 원하는 젊은 여성 환자에서 EMA/CO (Etoposide, methotrexate, actinomycin D/ cyclophosphamide, vincristine) 항암화학요법 후 종양적출을 위한 시험개복술을 계획하여 자궁보존을 시도하였다. 그러나 항암화학요법에 대한 저항성을 나타내 자궁보존에 실패하고 자궁절제술을 시행하였다. 이에 저자들은 이 증례를 관련 문헌에 대한 고찰과 함께 보고하는 바이다.