[내 마음속 목자] 부부의 길을 가르쳐주신 총각 신부님

정유선 미래사목연구소 2017 사목정보 Vol.10 No.2

국내 의료 기관에서의 항원 검사를 통한 특정항원음성 혈액제제확보 가능성

정유선,박경운,홍윤지,황상미,김택수,송정한,한규섭 대한수혈학회 2014 大韓輸血學會誌 Vol.25 No.1

Background: When unexpected antibodies are identified, selection for specific antigen-negative blood units isneeded in order to ensure transfusion safety. We estimated the number of blood units required for antigen testingto obtain specific antigen-negative units in Korean medical institutes. Methods: We analyzed cases of selection for specific antigen-negative units for recipients who had antibodies identifiedin Seoul National University Bundang hospital from January 2008 to December 2010 and cases entered into the KRBP(Korean Rare Blood Program) online database from July 2013 to February 2014 from eight medical institutes. Results: A total of 559 cases of 266 patients were analyzed. The antigen types requiring two units on average for onespecific antigen-negative unit were E, P1, and Lea. Three units on average were required for one Fyb-negative blood unit,four units for one Jka-negative unit, four units for one Jkb-negative unit, 4.5 units for one Leb-negative unit, five unitsfor one C-negative unit, six units for one M-negative unit, and seven units for one S-negative unit. In cases of obtainingspecific antigen-negative units for more than one antigen type, three units on average were required for one E, c-negativeunit and seven units for one C, e-negative unit. Other multiple antigen-negative units required up to 20 units. Conclusion: The accurate antigen-negative frequency in the Korean population should be investigated. Followingthis effort, the number of blood units required for selection of specific antigen-negative units could be predictedand practical measures for obtaining specific antigen-negative blood units could be suggested for Korean medicalinstitutes.

한국인에서 혈소판과 단구의 CD36 결핍 빈도

정유선,박경운,황상미,김명신,홍윤지,김택수,송정한,한규섭 대한수혈학회 2014 大韓輸血學會誌 Vol.25 No.1

Background: CD36 deficiency was first identified in a patient who showed refractoriness to HLA-matched platelettransfusion. CD36 deficiency can be divided into two subgroups. The type I phenotype is characterized by plateletsand monocytes exhibiting CD36 deficiency. The type II phenotype lacks surface expression of CD36 in plateletsonly. In this study, the frequency of type I and type II CD36 deficiency in Koreans was evaluated. Methods: A total of 220 samples were randomly selected from subjects who requested CBC testing from August2013 to February 2014. The expression levels of CD36 on platelets and monocytes were analyzed by flow cytometryusing FITC-conjugated CD36 antibodies. Correlation between the median fluorescence intensity of CD36 and thenumber of platelets or monocytes was evaluated using Pearson’s correlation coefficient. Results: Type I phenotype, lacking CD36 on platelets and monocytes, was present in 0.9% and type II, lackingCD36 on platelets, was present in 3.2%. The median fluorescence intensity of CD36 did not show correlationwith the count of platelets or monocytes. Conclusion: Type I subjects may produce alloantibodies against CD36 following transfusion or pregnancy, leadingto refractoriness to HLA-matched platelet transfusion, post-transfusion purpura, or neonatal immunethrombocytopenia. Studies to determine exact frequency of CD36 deficiency in Koreans, including a largerpopulation, should be conducted, and more case reports on patients immunized against CD36 are also needed inorder to elucidate the clinical importance and relevance of CD36 deficiency testing and the transfusion ofCD36-deficient platelets.

미국의 위해성 평가 및 완화전략 공유시스템의 현황 및 시사점

정유선,송윤경,양보람,김아리,이승미 한국보건사회약료경영학회 2022 한국보건사회약료경영학회지 Vol.10 No.1

In the United States, the Risk Evaluation and Mitigation Strategy (REMS) has been implemented since 2007, and generic products of original drugs under REMS are also subject to REMS. South Korea has adopted a Risk Management Plan (RMP) to ensure drug safety throughout the drug’s product cycle in 2015. This paper reviews the current status of a Shared System (SS) REMS in the United States and the SS REMS of isotretinoin (iPLEDGE program) to understand its implications for Korea's RMP system. In the United States, generic manufacturers can either individually implement REMS or collaborate with original manufacturers. SS REMS benefits the shareholders by reducing the work burden of participating companies, sharing development costs, and maintaining consistency of risk management in clinical settings. The iPLEDGE program is the oldest and most representative SS REMS. It was developed to prevent potential fetal exposure to isotretinoin. A central, systematic risk management website inspects isotretinoin distribution, prescribing, dispensing, and utilization. For example, prescribing isotretinoin is permitted when the results of pregnancy lab tests and contraceptive methods are entered into the website. Since more generic drugs are expected to enter the market in Korea, the SS of RMP can be a systematic approach to maintain a coherent risk mitigation strategy and reduce the operational burden of manufacturers.

원주에 사는 즐거움

정유선 한국여성민우회 2013 함께가는 여성 Vol.214 No.-

증강현실 기술을 활용한 중국어 교과 지도방안 연구 - 국내 중국인 결혼이민자 가정의 이중언어 사용 자녀를 중심으로

정유선,한희정 한국중국언어문화연구회 2016 한중언어문화연구 Vol.- No.42

‘Augmented reality’ technology that shows real time virtual information combined with real world has entered commercialization stage. As Boeing’s Tom caudell explained virtual image of plane wire assembly process by overlapping with the real screen in 1990, the term augmented reality was firstly used. Augmented reality stayed at research development and test application stage until mid 2000s, however it has entered commercialization stage recently as the smart phone with the functions as the terminal raised with camera and graphic treatment ability, radio communication with enough speed, and GPS, etc. Augmented reality is expected as a technology that could provide more improved immersion and sense of reality to user by providing real time combination of real world and virtual world, receiving high interest as a new education medium that could extend learning experience along with virtual reality as a type of mixed reality. To establish a virtual campus in a virtual reality and provide a virtual learning situation through avatar utilizing Second Life, etc., famous as an internet base virtual world is another representative case showing the barrier between reality and virtual world is gradually collapsing through technical development. Contextual learning of the reality is possible by providing virtual object by adding it to the real world simultaneously as enabling the user to see the real world of augmented reality. This enables us to do contextual learning related to real situation, and compose knowledge by ourselves not merely unilaterally receiving suggested knowledge given by the teacher passively by motivating learners’ positive operational activity. This is definite that learning contents service utilizing augmented reality technology would take center stage as a new alternative, which could promote sense of presence and immersion considering the educational paradigm of knowledge base information society based on bilateral communication requires high quality bilateral contents based on a new technology evading the existing unilateral educational contents.

Results of a Government-supported Newborn Hearing Screening Pilot Project in the 17 Cities and Provinces from 2014 to 2018 in Korea

정유선,오승하,박수경 대한의학회 2020 Journal of Korean medical science Vol.35 No.31

Background: The aim of this study was to present and analyze, for the first time, the results of a government-supported nationwide newborn hearing screening (NHS) pilot project in the 17 major cities and provinces of Korea. Methods: We analyzed a nationwide NHS database of 344,955 newborns in the pilot project from 2014 to 2018. The government supported the cost of one NHS and one diagnostic auditory brainstem response (ABR) test. Hearing loss (HL) was defined as ≥ 40 dB nHL on either side of the ABR threshold test. Results: Most NHS tests were performed in the maternity clinics (91.5%). In regions with lack of maternity clinics, the screening rate of local clinics was high (Jeju: 31.1% and Sejong: 12.9%). In most regions, automated ABR was mainly used for screening test (89.7%), but Gangwon (32.7%), Jeju (31.0%), and Jeonbuk (29.6%) performed more NHS tests using (automated) otoacoustic emissions than other regions. The mean referral rate was 1.5%, but the overall diagnostic ABR rate was low at 18.5%. The referral rates of Busan (0.6%) and Gyeongnam (0.9%) were lower than 1%, and Jeju's referral rate was 7.3%. Prevalence of HL including unilateral HL was 0.12%. Conclusion: Depending on the cities and provinces, there were significant differences in the screening rates and referral rates by hospital type and NHS method. For successful early hearing detection and intervention (EHDI) and quality control, it will be necessary to support and manage EHDI according to regional NHS's characteristics and ensure that the whole country conducts EHDI as standard.

국내 비한국계 중국인 결혼이민자 가족 자녀 대상 중국어교육에 대한 몇 가지 제언

정유선,이다혜 한국중국언어문화연구회 2015 한중언어문화연구 Vol.- No.37

The number of multicultural families accounts for 2% of whole number of population. Among them, the multicultural family consisting of non-Korean Chinese and Korean is of the greatest importance showing 20,635(66.2%) marriage cases between Korean man and non-Korean Chinese woman and 5,042(42.2%) between non-Korean Chinese man and Korean woman. For those reasons, the number of children from multicultural family has been increasing. According to Safety Executive, the number of the multicultural children has steadily increased from 44,285 in 2007 to 204,204 this year. As the percentage of non-Korean Chinese married Immigrant family is 50.7%, it takes the first place. In contrast with this trend, marriage based immigrants who have Chinese nationality still complain of difficulties in settling down in Korea. Due to the environment that using Korean language is preferred, they don't have any choice but to use Korean at home, leading to the lack of communication with children using Chinese. As a result, emotional connectedness is going down between parents and children and they have an identity crisis. They have become various elements in home problems and can influence negative effects on social unification. It's the right time to implement Chinese teaching for the spouse and children of non-Korean Chinese married Immigrant family with an active and tolerant attitude to narrow down the gap of problems and to have the influence as a global society. However, it is true that a discussion or enforcement on the social recognition and need of this problems has not been treated. Thus, this study proposed Chinese teaching for the children of non-Korean Chinese married Immigrant family.

‘揚州淸曲’考

鄭有善 한국중국소설학회 2008 中國小說論叢 Vol.28 No.-

扬州清曲是在扬州形成的,明清代流行于江苏城苏州、南京、扬州、镇江一带的歌唱艺术,曾也叫扬州小唱、扬州小曲、扬州小调、光陵清曲、维扬清曲、扬州南音、扬州六书。扬州清曲不依靠表演、说白、粉状,只用演唱者的高度的歌唱表演离合悲欢等情节故事来吸引听众的伎艺。这种伎艺至今还保存明清代演唱的493种传统曲目,116种以上曲牌。因此扬州清曲是可窥明清时期音乐、表演样相的‘活化石’。扬州清曲对全国14个省的23个传统戏曲和各种曲艺品种都或多或少给影响,而有些曲艺系由扬州清曲直接衍变而成。由于这些原因认定保存价值,扬州清曲是 申报2003年11月在巴利开的世界无形文化遗产的重要中国无形遗产。对这个曲艺更注视的就是笔者把胚胎、形成、流行于明清时期在经济、文化中心的江苏一带的扬州清曲看成当时反映这地域文化的文化产物。扬州清曲由扬州地域表演艺术中文化消费者的要求有很快的曲调变化、必要高度的演唱技术而简单的和小规模的表演方式、各界个曾的享有层,抱有扬州地域特性的,一个一个都有扬州文化形态。因此本论文通过扬州清曲的形成背景、表演流通经路,表演样相等的文化系统和文化商品考察,试图解明明清时期总体的人文学的核心商业资本和文化发展的互相关系。

封神戱 검보 아이콘 읽기

정유선 한국중국소설학회 2009 中國小說論叢 Vol.30 No.-

脸谱融合了与剧情中心思想和出场人物有关的各种叙事性要素, 是增添戏剧艺术功能的手段之一。脸谱从视觉角度再现了主导戏剧故事发展的主人公的性格、身份、年龄、特长、心态动向、心理状态以及周围的环境和舞台背景效果等。脸谱是戏剧中向观众传达信息一大重要媒体。 特别是传统剧中主要靠肢体动作来表演的净角和丑角, 作为剧中的次要人物他们并不能完全通过语言或唱腔来充分表达人物感情和在剧中所处的情况, 所以脸谱对于这一点也起到了相当大的补助作用。净和丑在面部通过视觉性的象征符号来补充肢体演技无法表达的个人思想和人物信息, 而这些特定的象征符号也就成了在漫长岁月里与观众形成的一种约定。而中国传统戏的舞台形态可以看作是这种现象形成的一大原因。中国传统戏剧的舞台是沿着观众席突出的舞台, 观众可以从正面和两侧看到演员的表演行为。由于三面都能看到舞台, 舞台上很难使用一些真实的背景和道具, 同样也很难根据剧情来分隔舞台空间。演员的化妆即脸谱可以看作是对应中国传统戏剧舞台不足之处的一大方法。笔者正是要通过研究来表现除简略道具和舞台装饰外, 脸谱所展现的补充甚至是取代部分舞台装饰的作用。 脸谱中所使用的视觉表现方式主要有色彩、构图和图标(icon)色彩和构图主要表现人物在剧中的比重和善恶、性格的立体类型。图标则是通过在不同的舞台背景、小道具、以及各种人物特征和长相等多种情况下长时间来与观众达成一致的图案来表达的。 本文将以在传统戏中脸谱图标相对丰富的<封神戏>脸谱为对象进行研究。首先在确定封神戏内容和出场人物脸谱的图标后, 通过考察每个出场人物脸谱上图标的表现方式, 最终把握脸谱图标的产生和构成原理。