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溫熱및 寒冷이 成熱白鼠 肝細胞핵分裂에 미치는 影響에 關한 實驗的 硏究
鄭九鉉 中央醫學社 1965 中央醫學 Vol.8 No.6
In order to observe the effect of, the temperatures upon the hepatic cell mitosis, albino rats weighing from 120 gm, to 150 gm were kept in an incubator at the temperature of 32 °C, or in a refrigerator at the temperature of minus 10 °C for a certain period respectively, and than hepatic cell mitosis was timely observed. In another hand, a small amount of serum of the albino rats which have been exposed in the above two temperatures was injected into unexposed normal albino rats, and the effect of injected sera upon the hepatic cell rnitosis also was observed? And the following conclusions were obtained. 1) In the group of the albino rats which were exposed in the temperature of .30°C, for a certain period, their hepatic cell mitosis has shown the rapid increase in it's activity since 4 houter after exposure, and thereafter reached in 12 hours the maximum level which is five to six times of that in the unexposed group, 24 hours later it returned to the normal level due to the gradual decrease in it's activity, However, the continuous decrease of hepatic cell mitosis reaches the minimum level in 48 to 72 hours and returned again to the normal level. 2) In the group of the albino rats which were exposured in the temperature of minus 10°C for a certain period, the hepatic cell mitosis also has shown the relatively rapid increase in it's activity since 4 to 8 hours after exposure and reached the maximum level in 18 hours, which is more than two times of the unexposed, "Thereafter the hepatic cell mitosis decreased in it's activity relatively repidly in 'one fourth of the normal level in 48 to 72 hours, And a tendency returning to the normal level in one week due to gradual decrease in mitotic activity was also observed. 3) In the group injected with the serum of the albino rats exposed in the temperature of 32°C, for a certain period, the hepatic cell mitosis seemed to slightly decreased in it's activity immediately after the injection. However, thereafter it showed the rapid increase in it's activity reaching the maximum level in 8 to 12 hours, which is about two times of that in the uninjected, And then the relatively rapid decrease in mitotic activity was shown and it became about me third .of that in the uninjected in 24 hours, and returned to the normal level due to the gradual: decrease thereafter. 4) In the group injected with the serum of the albino rats exposed in the temperature of minus 10°C for a certain period, a tendency of more. or less slight decrease of the hepatic cell mitosis was shown immediately after the injection. And the hepatic cell mitosis reached the maximum level in 12, hours which is. about two times of that in the uninjected due to the rapid increase in it's, activity. However, in. 48 hours later it became far -less active than the normal. and thereafter by gradual increase restored to the normal level again. 5) Therefore, it may be suggested that the temperature of 32°C. and animus 10°C have possibly an effect upon the hepatic cell mitosis of albino rats, which at first: stimulated, thereafter slightly inhibited, and finally restored to the normal condition. And it is also suggested that the sera of albino rats exposed in the above temperatures have possibly an effect upon the hepatic cell mitosis which, at first more or less is inhibited and followed by the rapid increase in it's activity thereafter, And then it showed the relatively rapid decrease in activity and finally returned to the normal condition. It seems likely that there may possibly be two factors both stimulating and inhibiting the hepatic cell mitosis in the sera of the albino rats exposed in the above mentioned temperatures.
Wear Characteristics of Atomic Force Microscopy Tips: A Reivew
정구현 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.
Based on the interaction between the extremely sharp tip and the sample, atomic force microscopy (AFM) has been widely utilizedto explore the surface phenomena at the nano-scale. During the AFM measurements such as topographical imaging, forcespectroscopy, and friction loop, the tip is often damaged due to wear, which in turn forms the artifacts in the AFM images and increasethe uncertainties of material properties measured by an AFM. In this paper, based on the numerous studies performed by researchers,the wear characteristics of silicon- and carbon-based tips, and metal coated tips are comprehensively reviewed, including thecharacterization methods and models for tip wear, with an aim to provide an overview of key findings of tip wear that can be usefulfor AFM scientists and engineers.
머신비전을 이용한 나사 머리 성형 펀치의 검사 알고리즘
정구현,정성엽,Jeong, Ku Hyeon,Chung, Seong Youb 한국교통대학교 융복합기술연구소 2013 융ㆍ복합기술연구소 논문집 Vol.3 No.2
This paper proposes a vision-based inspection algorithm for a punch which is used when forming the head of the small screws. To maintain good quality of punch, the precise inspection of its dimension and the depth of the punch head is important. A CCD camera and an illumination dome light are used to measure its dimensions. And a structured line laser is also used to measure the depth of the punch head. Resolution and visible area depend on setup between laser and camera which is determined using CAD-based simulation. The proposed method is successfully evaluated using experiment on #2 punch.
Masticator Space Tumor Mimicking Temporomandibular Disorder Presenting Facial Swelling and Trismus
정구현,박조은,김미은,김혜경 대한안면통증∙구강내과학회 2019 Journal of Oral Medicine and Pain Vol.44 No.2
Temporomandibular disorders (TMD), involving the masticator system of temporomandibular joint (TMJ) and masticator muscle, can be characterized with the cardinal signs and symptoms of jaw pain, noises and limitation of mandibular range of motion. However, TMD requires differential diagnosis due to its heterogeneous characteristics with various causes despite the similar clinical profiles. Oral cancer involving TMJ and the masticator system, although infrequent, can be one of these causes and should be considered one of the most life-threatening disease mimicking TMDs. This report introduces a case of masticator space tumor originally diagnosed as TMD in a 73-year-old Korean female with previous history of brain tumor. The clinical signs and symptoms closely mimic that of TMD which may have disrupted differential diagnosis. We discuss here key points for suspecting TMDs of secondary origin, namely, that of cancer and the implications it has on dental clinicians.