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RISS 인기검색어
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- 저자 : 장지숙(Jee-Sook Jang) (검색결과 2 건)
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이유라(You-Ra Lee),신정호(Jong-Ho Shin),민성호(Seong-Ho Min),김태희(Tae-Hui Kim),김민혁(Min-Hyuck Kim),장형민(Hyung-Min Chang),박기창(Ki-Chang Park),안정숙(Joung-Sook Ah),전영안(Yong-An Jeon),장지숙(Jee-Sook Jang) 한국중독정신의학회 2005 중독정신의학 Vol.9 No.1
Objectives:This study was designed to find out the changes of alcohol use behavior and it’s attributing factors through two surveys conducted in 1998 and 2004 in a rural community. Methods:We selected 116 problem drinkers and 116 matched non-problem drinkers among 480 men of the first survey. We surveyed basic epidemiologic data and alcohol use behavior with several questionnaires. Results:The results were as follows : 1) Drinking amount and frequency decreased with increasing age. 2) More than half among previous problem drinkers did not show any significant change in their alcohol use behavior. 3) Most of previous non-problem drinkers maintained their past alcohol use behavior. 4) Continuous problem drinkers had larger amount of past alcohol drinking than no more problem drinkers. They had lower scores on awareness of negative consequence, higher scores on drinking for coping strategy of Alcohol Effects Questionnaire (AEQ) and higher scores on drinking urge to relieve hangover of the Severity of Alcohol Dependence Questionnaire (SADQ) than no more problem drinkers. 5) Continuous problem drinkers showed more smoking and earlier drinking than continuous non-problem drinkers. 6) Continuous problem drinkers became poorer than no more problem drinkers. Conclusions: Continuous problem drinking pattern was associated with larger amount of past alcohol drinking, higher drinking frequency, higher drinking urge to relieve hangover, higher use of drinking for coping strategy and less awareness of negative consequence.
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Bortezomib과 Dexamthasone으로 치료한 골수외 형질세포종 4예
백종현,이은영,장리라,손창배,신은경,서정아,이지숙,이호섭,이상민,신성훈,김양수 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2
Despite the use of aggressive local and systemic treatment including autologous stem cell transplantation in multiple myeloma, extramedullary recurrences are common and the prognosis of these patients is poor. Many novel drugs such as thalidomide, lenalidomide and bortezomib improve the response of treatment of multiple myeloma, but some reports failed to describe thalidomide has effect in extramedullary plasmacytoma. Recent data report on the successful treatment plasmacytomas with bortezomib in patients with advanced multiple myeloma. We treated 4 relapsed or refractory extramedullary plasmacytomas with bortezomib at our institution. We recognized all these extramedullary plasmacytomas decreased and showed more than partial response. This report lends support to the efficacy of bortezomib in the treatment of plasmacytoma and describes the safe use of bortezomib. Responses may, however, be of short duration. Therefore, despite our limited experience, we propose that bortezomib may be considered a therapeutic option for such patients who have risk of radiation therapy
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