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Premarin검사를 이용한 무월경환자에서의 시상하부-뇌하수체의 기능평가
이진우,나종구,Lee, J.W.,Rha, J.G. 대한생식의학회 1984 Clinical and Experimental Reproductive Medicine Vol.11 No.2
Hypothalamic-pituitary function in patients of 6 selected groups of amenorrhea was evaluated by performing premarin test. Selected amenorrheic patients were divided into 6 groups of Turner's syndrome(5), adrenogenital syndrome(3), Sheehan's syndrome(4), moderate hyperprolactinemia(3), severe hyperprolactinemia(9) and functional oligoamenorrhea(9) the diagnoses of which were performed according to modified our own protocol for management of amenorrheic patients. As control 20 normally cycling women in mid follicular phase determined by their symptothermal charts during last 6 months designed by WHO were compared. The premarin test which is one of the tests evaluating the hypothalamic-pituitary function by the principle of negative and positive feed back effect's of estrogen was performed by injecting 20 mg of premarin in volus intravenously. The levels of serum LH before, 24, 48, 72, 96 and 120 hours after injection of premarin were measured by double antibody technique radioimmunoassay the reagents of which were supplied by WHO. The results were as follows: 1. Both negative and positive feed back effects by exogenous estrogen were well preserved even in the patients of gonadal dysgenesis although the baseline levels were much higher than normal. 2. In the patients of Sheehan's syndrome one could observe the minimal response of feed back effect in the case with minimal pituitary function. 3, Androgens in adrenogenital syndrome and prolactin in hyperprolactinemia may suppress mainly the positive feed back effect rather than the negative one. The suppressive effect can be abolished by proper treatments which can eliminate those suppressive hormones. 4. This premarin test may be beneficial for predicting the result of clomiphene in ovulation induction.
이진우 한국농촌경제연구원 2022 해외곡물시장동향 Vol.11 No.6
금리인상에서 금리인하로, 즉 긴축(緊縮)에서 완화(緩和)로 돌아서는 것을 의미하는 'Fed's Pivot’을 월가에서조차 금리인상 폭을 75bp에서 50bp나 25bp로 낮추는 의미로 사용할 정도로 국제금융시장은 금년 들어 ‘빛의 속도’로 진행되고 있는 연준의 ‘인플레이션 파이팅’에 주목하고 있습니다. 그 동안 너무 주눅 들었다고 판단한 것일까요, 아니면 기운 달은 다시 찬다고 믿기에 그런 것일까요? 10월 들어, 즉 4분기에 접어들면서 증시는 그간의 하락세를 뒤로 하고 반등에 나서고 있으며 외환시장에서는 다소 시차를 두기는 했지만 美 달러화 가치의 급격한 하향조정이 펼쳐지고 있습니다. 섣부른 전망은 사양하겠습니다.