객혈 환자에서 기관지경술이나 기관지동맥색전술 시행 전의 다중절편 전산화 단층촬영의 유용성

이신재 ( Shin Jae Lee ),노지영 ( Ji Young Rho ),유승민 ( Seung Min Yoo ),김만득 ( Man Deuk Kim ),이지현 ( Ji Hyun Lee ),김은경 ( Eun Kyung Kim ),조영아 ( Young Ah Cho ),이상민 ( Sang Min Lee ) 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.68 No.2

Background: Recently, many institutions have acquired multi-detector computed tomography (MDCT) systems. This made it easier and more convenient to use MDCT as a initial diagnostic modality for hemoptysis. The purpose of this study was to evaluate the usefulness of MDCT before bronchoscopy and/or bronchial arterial embolization (BAE) for hemoptysis. Methods: We studied a total of 125 patients with hemoptysis who underwent, between 2006 and 2008, MDCT in a routine protocol before bronchoscopy and/or BAE. One hundred two patients underwent bronchoscopy and 29 patients underwent BAE. We compared the usefulness of MDCT and bronchoscopy for detecting the bleeding site and identifying the cause. We also evaluated our ability, using MDCT, to detect instances where the bronchial artery caused hemoptysis. Results: The rate of detection of a bleeding site was 75.5% on MDCT and 50.9% on bronchoscopy. MDCT and bronchoscopy detected the bleeding site in agreement in 62.7% of patients. MDCT alone found the bleeding site in 27.5% of cases. MDCT identified the cause of hemoptysis in 77.5% and bronchoscopy in 11.8%. In 29 patients who underwent BAE, we detected a total of 37 hypertrophied bronchial arteries that were causing hemoptysis. Of 37 bronchial arteries, 23 (62.2%) were depicted on MDCT. Conclusion: MDCT is superior to bronchoscopy for detecting the bleeding site and identifying the cause of hemoptysis. MDCT can also predict the side of affected bronchial artery with depiction of hypertrophied bronchial artery and localizing the bleeding site. Doing MDCT before bronchoscopy and BAE can provide a guideline for the next step.

자궁내막암의 치료 후 루틴 추적검사 방법으로서 FDG-PET/CT의 유용성

이신재 ( Shin Jae Lee ),전태주 ( Tae Joo Jeon ),김승조 ( Seung Jo Kim ),김희진 ( Hee Jin Kim ),안희정 ( Hee Jung An ) 대한핵의학회 2009 핵의학 분자영상 Vol.43 No.4

목적: 자궁내막암의 치료 후 루틴 추적관찰로써의 FDG-PET/CT의 유용성에 대해 알아보고자 하였다. 대상 및 방법: 자궁내막암으로 치료 받은 환자 중 2004년 1월 1일부터 2008년 1월 31일 사이에 FDG-PET/CT를 시행한 101명의 환자(25-79세, 평균 50.6세)를 대상으로 하였다. 모든 환자에서 종양표지자와 다른 영상의학적 검사(CT, MR)에 대해서도 함께 검토하였다. FDG-PET/CT상 국소 FDG 섭취를 보인 병변을 benign, equivocal, malignant로 분류하였고, equivocal과 maliganat 병변에 대하여 조직학적 혹은 임상적으로 재발유무를 판정하였다. 결과: FDG-PET/CT상 강한 섭취를 보인 경우는 19명의 30개의 병변이었다. Malignant 섭취를 보인 환자는14명이었고, 이중 11예가 재발로 확인되었다. Equivocal 병변을 보인 환자는 5명이었고, 이중 1예가 재발로 확인되었다. 위음성을 보인 경우는 2예가 있었고, 모두 복강내 암종증 환자로 진단되었다. 이상의 결과를 종합하였을 때, 자궁내막암의 치료 후 재발의 평가에 대한 전반적인 결과는 예민도 86 %, 특이도 92 %, 양성예측도 63 %, 음성예측도 98 %, 그리고 정확도는 91 %였다. 결론: 자궁내막암의 치료 후 루틴 추적관찰로써 FDG-PET/CT를 시행할 경우 높은 예민도, 특이도로 재발의 진단에 도움이 될 뿐만 아니라 높은 음성 예측도로 인하여 FDG-PET/CT상 음성인 경우 불필요한 추가 검사를 피할 수 있을 것으로 기대된다. Purpose: The aim of this study was to evaluate the usefulness of FDG-PET/CT as follow up imaging tool in patients with endometrial cancer after therapy. Material and Methods: One hundred one patients with endometrial cancer who underwent FDG PET/CT after the treatment of this disease were included in this study population (25-79 yr old, Mean age 50.6 yr old) and all these patients also performed various laboratory and imaging studies such as serum tumor marker, CT or MRI. The lesions having increased focal FDG uptake were classified into benign, equivocal, and malignant one according to their pattern and activity. Tumor recurrence was confirmed by histopathological results and other clinical and imaging data. Results: Among the 19 patients with 30 malignant or equivocal hot uptakes, 11 of 14 patients supposed to be malignant finding in PET/CT were proved to be tumor recurrence, while one of 5 patients with equivocal lesions were recurred malignancy. Two false negative cases were turned out to be peritoneal carcinomatosis. Estimated sensitivity, specificity and accuracy of PET/CT for diagnosis of recurrence in endometrial carcinoma after treatment were 86 %, 92 % and 91%, respectively. Positive and negative predictive values in the same issue were 63% and 98%, respectively. Conclusion: FDG-PET/CT is useful for regular work up of endometrial carcinoma after the treatment because of its high negative predictive value as well as high sensitivity and specificity. (Nucl Med Mol Imaging 2009;43(4):301-308)

혀 세정기가 부착된 수동칫솔이 치아와 혀의 세정도 및 구취 관리도에 미치는 영향

김태일,홍삼표,이신재,강봉선,오영상,김인경,오미현,Kim, Tae-Il,Hong, Sam-Pyo,Lee, Shin-Jae,Kang, Bong-Sun,Oh, Young-Sang,Kim, In-Kyung,Oh, Mi-Hyun 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.4

Purpose: The aim of this study was to investigate the effect of tongue cleaner-equipped manual toothbrush on tooth cleanness, tongue cleanness and malodor index. Materials and methods: 504 subjects were included in this study. At 1st visit, basic information such as age, sex, smoking amount and alcohol consumption was recorded. Self assessment by individual subjects was performed regarding satisfaction to old toothbrush and toothbrushing habit. Tooth cleanness, tongue cleanness and malodor index was assessed by professional researcher. Tongue cleaner-equipped manual toothbrush was given to each subject with proper toothbrushing instruction. After 1 month passed, self assessment and researcher assessment regarding the same index were performed and analyzed statistically by chi-square test. Results: At 1st visit subjects seem to ignore tongue cleansing and showed poor tooth cleanness index, tongue cleanness index and malodor index, however the same subjects were motivated to clean their tongue and teeth and presented statistically improved distribution pattern in tooth cleanness index, tongue cleanness index and malodor index after using tongue cleaner-equipped manual toothbrush(p<0.01). Satisfaction to tongue cleaner-equipped manual toothbrush was 98%. Conclusion: Tongue cleaner-equipped manual toothbrush would be an effective tool for maintaining good oral hygiene through improving tooth and tongue cleanness and preventing malodor formation.

한방 공공의료의 활성화에 관한 연구 - 공중보건 한의사의 활동을 중심으로 -

이상구,문옥륜,박송림,이신재,윤태호,정백근,문용,Yi Sang-Gu,Moon Ok-Ryun,Piao Song-Lin,Lee Shin-Jae,Yoon Tae-Ho,Jeong Baek-Geun,Wen Yong 대한예방한의학회 2000 대한예방한의학회지 Vol.4 No.1

From 1998, Oriental Medical Physicians(OMP) is distributed in Public Health Sector. but long term plan for Oriental Medicine in Public Health is not existed. So, this study is designed for the activation of OMP Subjects in this study were comprised 3 groups of oriental medicine related persons, the group of which are Students of 11 Oriental Medical Schools, Oriental Medical Physicians in Public Health Sector, Specialist Croup of Oriental medicine Policy(total 1,458 persons). Data were collected from July 1st to November 30, 1999. Direct interview with key persons, systematic interview by using of interview protocol, e-mail and facsimile have been conducted. The results of survey were coded by Excel 5.0, and analysed with SAS 6.12 statistical package. Inter-group difference determined by T-test, and descriptive statistics have been examined. Major findings can be epitomized as follows. 1) OMP disposition to multifarious organizations and institutes such as Public Health Centers, Public Health Sub-centers, Public Hospitals, Private Hospitals in Remote-Vulnerable Area, Community Social Welfare Centers, Institutes for Heath Policy Research, etc, will promise an effective use of Oriental Medical Physician. 2) Average number of patients treated by OMP was 22.8, average budget for oriental medical department, in which OMP were affiliated, was 39.6 million Won per year. Direct cost per every patient visit was 7,210.9 Won, which is considered expensive for public health service. Therefore, development and transformation for Oriental Medical Service in Public Health Sector is desirable in economic and political aspects. 3) It is recommended that ${\ulcorner}Advisory\;Committee{\lrcorner},{\ulcorner}Planning\;Commission\;for\; Public\;Health\;in\;Oriental\;Medicine{\lrcorner}$ should be established for the activation and for the support of Oriental Medical Physician in Public Health Sector, 4) Most effective programmes for oriental public health doctor are health service programmes for the elderly, Home health visit, chronic degenerative disease control services(p<0.001). 5) Standard guideline for facilities and equipments of Oriental Medicine Department in Public Health Center is needed for optimal supply of resources and activation of public health activity.

임플란트의 새로운 응용 - 임플란트 매개 약물 전달 시스템

박영석(Young-Seok Park),이신재(Shin-Jae Lee),황치일(Chee IL Hwang) 대한치과의사협회 2014 대한치과의사협회지 Vol.52 No.9

The restorative treatment with dental implants in edentulous patients has been a well documented treatment modality proven in experimental studies and long term clinical investigations. The aim of this paper is to introduce the implant mediated drug delivery system as a novel application of endosseous implants. The system is composed of hollow cylindric implants which has multiple microholes for drug delivery. For this purpose, the general outlines of drug delivery system and drug delivery route is discussed briefly. In addition, this paper deals with the results of experiments done up to now and the future perspective of the system.

건설위험직종 작업자의 위험체감도 평가

손기상 ( Ki Sang Son ),이신재 ( Shin Jae Lee ) 한국안전학회 2006 한국안전학회지 Vol.21 No.3

ADCP 품질관리를 위한 2017 ADCP Intercomparison 대회 결과

김동구(Kim, Donggu),이찬주(Lee, Chanjoo),이신재(Lee, Shin Jae),정상화(Jung, Sang Hwa),김남규(Kim, Nam Gyu) 대한토목학회 2017 대한토목학회 학술대회 Vol.2017 No.10

스플라인 함수를 이용한 한국인 키 기준 성장 곡선 구성과 최종 키 예측 연구

안홍석(Houng-Seok An),이신재(Shin-Jae Lee) 대한치과교정학회 2007 대한치과교정학회지 Vol.37 No.1

Objective: Evaluation of individual growth is important in orthodontics. The aim of this study was to develop a convenient software that can evaluate current growth status and predict further growth.<br> Methods: Stature data of 2 to 20 year-old Koreans (4893 boys and 4987 girls) were extracted from a nationwide data. Age-sex-specific continuous functions describing percentile growth curves were constructed using natural cubic spline function (NCSF). Then, final stature prediction algorithm was developed and its validity was tested using longitudinal series of stature measurements on randomly selected 200 samples. Various accuracy measurements and analyses of errors between observed and predicted stature using NCSF growth curves were performed.<br> Results: NCSF growth curves were shown to be excellent models in describing reference percentile stature growth curie over age. The prediction accuracy compared favorably with previous prediction models, even more accurate. The current prediction models gave more accurate results in girls than boys. Although the prediction accuracy was high, the error pattern of the validation data showed that in most cases, there were a lot of residuals with the same sign, suggestive of autocorrelation among them.<br> Conclusion: More sophisticated growth prediction algorithm is warranted to enhance a more appropriate goodness of model fit for individual growth. 본 연구는 청소년의 교정 치료 시 중요한 교정 환자의 성장 평가 및 잔여 성장량 예측 방법을 개발하기 위하여 시행되었다. 이를 위하여 한국인의 전국적 표본 자료 중에서 2 ~20세 남자 4,893명, 여자 4,987명의 키 자료를 이용하여 성별 연령별 키에 대한 성장 곡선을 3차 스플라인 함수(NCSF)로 구현하였다. 이후 성장 예측 알고리즘을 개발하고 이를 임의로 선택된 200명의 종단 성장 자료를 이용하여 검증하였다. 검증에는 최종 키 예측 정확성과 검증 표본의 모든 연령에 대한 키 예측 오차 분석 및 NCSF 성장 곡선의 적합성 검사가 포함되었다. 그 결과 NCSF 성장 곡선은 기준 성장 곡선을 표현하는데 매우 적합한 것으로 나타났으며 최종 키 예측 정확성도 높았다. 또한 예측 정확성은 남자 보다 여자가 유의하게 높았다. 이러한 결과에도 불구하고 검증 표본의 모든 연령에 대한 키 예측 오차의 양상이 독립성과 정규성이 부족한 단점도 나타났다. 결론적으로 본 연구 결과 도출된 NCSF 성장 곡선을 이용한 성장 예측 방법의 높은 정확성에도 불구하고 개인의 종단 성장에 좀 더 적합한 성장 모형의 개발이 필요할 것으로 생각되었다.

가정환경 특성에 따른 아동의 성장발육과 성인신장 추정치

박순영(Sun Young Pak),이종인(Jong In Lee),이신재(Shin Jae Lee),김희경(Hee Kyoung Kim),안홍석(Hong Seok An) 한국발육발달학회 2008 한국발육발달학회지 Vol.16 No.4

This research explored effects of home environmental characteristics on physical growth and adult stature estimates of sixth-graders. The sample children have been the research participants of Seoul Child Panel Study that has been conducted since 2004. The children`s physical growth was measured by Height for Age Z Score (HAZ), Body Mass Index for Age Z Score (BMIZ), and adult stature estimates. Their home environmental characteristics were measured by parents` education levels, family`s experiences of poverty, type of family (i.e. biparental or single parental type), and number of child` siblings. The data for this study were collected in the year of 2006 by collecting school records on the height and weight of 1,092 children and conducting self-administered surveys to the children`s parents. The data analysis methods employed include descriptive statistics, t test, One-Way ANOVA, and multiple stepwise linear regression analysis. The results suggest that variables such as parents` education level, family poverty, and number of child` siblings significantly explain children`s physical growth. However, type of family was not found to be statistically significant factor for physical growth in children. Father`s college education positively predicted children`s current stature and estimated adult height. Family`s experience of poverty at the time of research and high number of siblings negatively predicted BMIZ scores. The research results suggest that father`s education level is significant for long-term growth of Korean children while family poverty and number of siblings are significant for their short-term growth.

냉각탑 충진재 개발에 관한 연구

김영수(Young-Soo Kim),박수돌(Soo-Doll Park),이신재(Shin-Jae Lee) 대한설비공학회 2000 대한설비공학회 학술발표대회논문집 Vol.2000 No.-