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        동종 골수 이식 환자의 감염 양상

        신완식(Wan Shik Shin),한치화(Chi Hwa Han),유석환(Suk Hwan Yoo),박종원(Chong Won Park),강문원(Moon Won Kang),김춘추(Choon Choo Kim),김동집(Dong Jip Kim),정희영(Hee Young Chung),김학기(Hak Ki Kim),최일봉(Il Bong Choi) 대한내과학회 1991 대한내과학회지 Vol.41 No.1

        N/A We studied, retrospectively, the patterns of infection in 50 febrile, allogeneic bone marrow transplantation patients during the period from March 1983 to February 1989 at St. Mary's Hospital. The results were as follows: 1) Out of 50 patients, 35 were diagnosed with leukemia and 15 with aplastic anemia. In the leukemic patients, 11 had acute lymphocytic leukemia, 12 had acute myelogenous leukemia, and 12 had chronic myelogenous leukemia. 2) There were a total of 99 febrile episodes. Thirtyseven episodes (37. 4%) were during the early post-bone marrow transplantation before engraftment (<3-4 wks), 22 episodes (22.2%) during after-engraitment period (<100 days), 29 episodes (29.3%) during the late post-transplantation period, and 11 episodes (11.1%) during the pre-transplantation period. 3) Frequent sites of infection were in the lung (24 episodes, 42.7%), in the blood (10 episodes, 16.9%), and in the skin and soft tissue (7 episdodes, 11.9%) in decreasing order of the total documented infection, and 30 cases (30.3%) were microbiologically documented infections, while 29 cases (29.3%) were clinically documented infections. 4) The radiologic patterns of lung infiltration revealed the interstitial type to be the most frequent (14 cases, 58.4%). The nodular and the consolidation type of pattern were also present (5 cases, respectively). 5) The causative organisms for microbiologically documented infection were Gram negative organisms in 14 cases (34.1%), Gram positive organisms in 13 cases (31.7%), fungus in 6 cases (14.7%), M. tuberculosis in 2 cases (4.9%), and mixed organisms in 6'cases (14.6%). 6) Out of a total of 1420 cases of surveillence culture, organisms were cultured in 164 of these cases (11.5%), the positive cultures were from the oropharynx with 37 cases (22.8%), the axilla with 32 cases (19.5%), and the groin with 25 cases (15.2%). 7) Deaths in the patient population were due to complications of infection (1 case), graft failure (2 cases), graft rejection (2 cases), relapse of disease (5 cases), renal failure (1 case), and veno-occulsive disease (1 case). Rapid diagnosis, powerful treatment and the prevention of infection after bone marrow transplantation are thought to be able to reduce the number of deaths. In the future, further research and techniques aimed at preventing and treating viral infections need to be estabilished.

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        십이지장의 원발성 악성선암종

        김부성(Boo Sung Kim),정진우(Jin Wu Jeong),이창돈(Chang Don Lee),이성(Sung Lee),한남익(Nam Ik Han),김병기(Byong Ki Kim),홍설유(Seol Yun Hong),유석환(Suk Hwan Yoo) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1

        Primary adenocarcinoma of the duodenum is an uncommon codition. It represents about 0.3% of all malignant neoplasms of the gastrointestinal tract and 25-45% of malignant neoplasms of the small intestine. The first documented case of the duodenal carcinoma was described by Hamburger 1746. Since then, only 694 cases have been presented in the literature up to the 1974. We have experienced a case of primary duodenal carcinoma, which was diagnosed by biopsies with gastrofibroscopic endoscopy. Therefore, we present here a case of duodenal carcinoma with a review of literture.

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