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      • 다수 무인기의 커버리지를 위한 그래프 컷을 이용한 신속한 영역분할 알고리즘

        안성준,김유단 한국항공우주학회 2013 한국항공우주학회 학술발표회 논문집 Vol.2013 No.11

        다수의 무인기에 커버리지 임무를 할당하는 것은 계산의 복잡도가 큰 NP-hard 문제에 속한다. 본 연구에서는 계산시간을 단축하기 위해 graph cut 을 기반으로 한 αβ -swap 알고리즘을 이용하여 주어진 영역을 적절하게 분할하는 알고리즘을 제안하였다. 제안한 알고리즘은 다수 무인기의 커버리지 문제를 여러 개의 단일 커버리지 문제로 바꾸기 때문에 단일 커버리지 알고리즘을 적용할 수 있고, 무인기간의 충돌을 고려할 필요가 없는 장점이 있다. 제안된 알고리즘의 성능을 검증하기 위해 다수의 무인기가 장애물 혹은 비행금지 구역이 있는 지역을 커버리지 하는 상황에 대한 수치 시뮬레이션을 수행하였다. Assigning coverage mission to Multiple UAVs is NP-hard problem. In this study, for computational efficiency, area partitioning algorithm is proposed using αβ -swap algorithm based on graph cuts technique. The proposed algorithm changes multiple UAVs coverage problem to several single UAV coverage problems. Therefore, single coverage algorithm can be used without collision avoidance among the UAVs. To verify the performance of the proposed algorithm, numerical simulations are performed for the situation that multiple UAVs cover a given area with obstacles and flight restricted areas.

      • KCI등재

        Topographic Progression of Keratoconus in the Korean Population

        안성준,김미금,위원량 대한안과학회 2013 Korean Journal of Ophthalmology Vol.27 No.3

        Purpose: To develop a criterion for determining the topographic progression of keratoconus and to analyze the prognostic factors of progression. Methods: Medical records of 211 eyes of 128 patients who had been followed up for more than 2 years on three or more occasions were retrospectively reviewed. Topographic parameters, including simulated K, corneal astigmatism, irregular astigmatism at 3 and 5 mm, thinnest-point pachymetry, anterior and posterior elevation,and inferior minus superior index, were used to determine topographic progression. Topographic progression was determined by the greatest kappa value associated with progression to corneal graft surgery. Eyes were separated into progressed and non-progressed groups on the basis of topographic progression. The association of clinical factors with topographic progression, including demographic factors, contact lens use, corneal erosion, and atopic history at the time of diagnosis, was assessed by logistic regression. Results: When topographic progression was defined as five or more progressed topographic parameters, the greatest kappa value (0.354) was obtained. Ninety-four of the 211 keratoconic eyes (44.5%) were identified as topographically progressed. Age at diagnosis was significantly different between the progressed and nonprogressed groups (22.2 vs. 24.7 years, p = 0.014). Logistic regression revealed that younger age at diagnosis was a risk factor for topographic progression (odds ratio, 0.948; 95% confidence interval, 0.907 to 0.991; p =0.010). Conclusions: We developed a criterion for evaluating topographic progression of keratoconus using diverse topographic indices. Younger age at diagnosis was associated with topographic progression of keratoconus.

      • KCI등재

        장애인 주거환경 평가항목 선정 연구

        안성준,이규일 한국문화공간건축학회 2015 한국문화공간건축학회논문집 Vol.- No.52

        As the population of persons with disabilities increases, one of the most important issues we face is enabling such members of our communities to live independently in their own homes. For this reason, the government has put public resources in order to provide residential convenience to persons with disabilities. This study aims at finding the households of persons with disabilities in need, and derivating barrier factors based on the type of disability and characteristic of the living behavior. In this study, the ways of further development which are demands according to types of disability and behavior characteristics, the frequency of remodeling and parts of environment improvement, the problems of remodeling have been investigated. As a result, evaluation item of residential environment for the disabled is selected as a major category 10 items and minor category 22 items.

      • KCI등재

        The Usefulness of Interferon-gamma Release Assay for Diagnosis of Tuberculosis-related Uveitis in Korea

        안성준,김고은,우세준,박규형 대한안과학회 2014 Korean Journal of Ophthalmology Vol.28 No.3

        Purpose: To evaluate the usefulness of the interferon-gamma release assay (IGRA) for diagnosing tuberculosis(TB)-related uveitis (TRU). Methods: Records from 181 patients with ocular signs and symptoms suggestive of TRU and intraocular inflammationof unknown etiology were reviewed. All subjects underwent clinical and laboratory testing, includingIGRA, to rule out presence of underlying disease. A diagnosis of presumed TRU was made based on an internist’sTB diagnosis and a patient’s response to anti-TB therapy. Sensitivity, specificity, and positive predictivevalues of IGRA for TRU diagnosis were calculated. Clinical characteristics were compared between patientswith positive and negative IGRA results. Results: The sensitivity and specificity of IGRA for TRU were 100% and 72.0%, respectively. Mean age, percentageof patients with retinal vasculitis, and the anatomic type of uveitis were significantly different betweenpatients with positive and negative IGRA results (all p ≤ 0.001). Positive IGRA rates and false-positive rateswere significantly different between age and anatomic type groups (both p = 0.001). The positive predictivevalue of the IGRA among patients with intraocular inflammation was high (70%) when all of younger age (≤40years), posterior uveitis, and retinal vasculitis were present. Conclusions: The IGRA is useful for diagnosing TRU in the Korean population, especially when it is used as ascreening test. Clinical characteristics, including younger age (≤40 years), posterior uveitis, and retinal vasculitisin IGRA-positive patients, increase the likelihood of the patient having TRU.

      • KCI등재

        급성 복통 환자의 감별 진단을 위한 응급 복부 초음파:COUCH (Complaint-oriented Ultrasonography with CHecklist) 접근법

        안성준,고찬영,김동언,김재철,도한호,신태용,이성실,김영식,하영록 대한응급의학회 2008 大韓應急醫學會誌 Vol.19 No.1

        Purpose: The purpose of this study was to verify objectively whether abdominal ultrasonography performed by emergency physicians (EP) in emergency departments (ED) immediately after history taking and physical examination could give effective diagnostic information and to check the feasibility and usefulness of the COUCH method. Methods: From May 1, 2005 to September 30, 2005 we recruited 368 patients who complained of abdominal pain in the ED. Senior level emergency physicians (EP) conducted history taking and physical examinations, following which they were asked for their suspected diagnosis and their level of confidence (from maximum 5 to minimum 1) regarding each diagnosis. The same EP then performed abdominal ultrasonography (US), using the COUCH method and were again asked for their suspected diagnosis and level of confidence. We compared the suspected diagnoses and levels of confidence before and after abdominal US by using the t-test. Results: A total of 106 patients (55 male, 51 female, average age 35.46±18.11 years) were enrolled. The number of patients with a suspected diagnosis of after history taking and physical examination only (2.43±0.5) was significantly greater than after abdominal US (1.34±0.5) (p<0.01). The level of confidences of suspected diagnosis of after history taking and physical examination only (3.43±1.14), by contrast, was less than after abdominal US (4.40±1.22) (p<0.01). Each year of postgraduate residents could have the same results after US. Conclusion: We found that abdominal ultrasonography could give EP more informations for pronouncing a correct diagnosis for patients with abdominal pain in the ED, and the COUCH method could lead the EP to get better training for ultrasonography and to diagnose more rapidly and accurately.

      • FBW 헬리콥터 비행제어법칙 자동생성코드 개발 프로세스 및 도구 개발

        안성준,조인제,양창덕,이한주 한국항공우주학회 2012 한국항공우주학회 학술발표회 논문집 Vol.2012 No.11

        전자식 비행제어시스템(Fly-By-Wire Flight Control System)이 적용된 헬리콥터의 제어법칙 설계 및 해석은 모델기반 설계기법(Model Based Design)을 사용하여 개발되고 있다. 모델기반 설계기법은 회전익 뿐만 아니라 고정익, 무인항공기, 자동차 산업에서도 널리 사용되고 있다. 모델기반 설계기법은 핵심기술인 시뮬레이션과 자동생성코드를 이용하여 개발기간 단축 및 개발리스크 감소라는 장점을 제공한다. 본 논문에서는 FBW 헬리콥터 비행제어법칙의 자동생성코드에 대해서 체계적인 기능검증을 위한 프로세스를 개발하고, 실제 FBW 헬리콥터 개발에 적용하여 비행제어법칙 자동생성코드의 기능검증을 수행한 내용에 대하여 정리하였다. The control law design and analysis environment of the FBW helicopter system have been developed using model base design method. The model based design is generally used in a aircraft, unmanned aerial system and automobile as well as rotorcraft development. The model based design provides many advantages such as development risk and schedule reduction using simulation and autocode generation. This paper describes a development of process for verification and validation of auto generated code for FBW helicopter flight control law and result of functional test.

      • KCI등재

        유니버설디자인 안내시스템 적용 방안 연구 - 저시력인, 고령자 등 편의시설을 중심으로 -

        안성준,이규일 한국공간디자인학회 2024 한국공간디자인학회논문집 Vol.19 No.3

        (연구배경 및 목적) 우리나라는 급속한 고령화로의 진입과 함께 2018년 고령사회로 진입하였으며, 초고령사회로의 진입을 바로 앞에 두고 있다. 또한 장애인의 자립과 사회참여에 대한 요구가 커지고 있으며, 이에 대응하고자 사회의 전반 분야에서 대응하고 있지만 아직 많이 부족한 실정이다. 사회참여 및 활동을 위해서는 이동 및 접근은 무엇보다 기본이 되어야 하며 우선되어야 할 것이다. 본 연구는 시설 이용자의 이동 및 접근성 향상을 위하여 저시력인, 고령자를 포함한 장애인 등 모두를 고려한 공간별 유니버설디자인 안내시스템의 대안을 제시하는 것을 목적으로 한다. (연구방법) 본 연구는 공간별 유니버설디자인 안내시스템의 대안을 제시하기 위하여 먼저, 국내외 안내시설 관련법에 대한 고찰을 통하여 국내법에 적용 가능한 규정을 검토한다. 그리고 유니버설디자인이 적용된 건축물을 선정하여 건축물 편의시설별 안내시설을 분류하고 접근로, 계단, 경사로, 복도 등 편의시설 종류별 설치 현황에 대해 조사한 후 적용 가능한 법 규정과 비교하여 고찰하였다. 이를 통해 규정의 개선이 필요한 항목을 도출하고 해당 항목의 조사표를 작성하여 고령자, 저시력인, 휠체어사용자, 발달장애인을 대상으로 선호도 및 만족도 등에 대한 설문조사를 진행함으로써 규정의 개선 방향성을 검증하였다. (결과) 접근로 공간의 안내부분은 유도 및 경고를 위해 음성안내, 촉지도, 청각경보 등이 요구된다. 출입문에서는 외여닫이문의 경우 손잡이 측에 실명과 함께 점자안내표지판이 설치되어야 할 것이다. 복도 및 통로 공간에서는 경사가 있는 부분의 시작 지점에는 시각장애인의 주의환기를 위해 점형블록을 설치해야 할 필요가 있으므로 이에 대한 관련규정 개정이 요구된다. 보행장애물과 관련하여 실내의 기둥과 같은 장애물이 잘 인지될 수 있도록 색의 명도, 색상, 채도 차이가 큰 재질로 마감하고 충돌시 안전 측면도 동시에 고려되어야 한다. 계단 또는 경사로와 주변 바닥면의 경우 색채의 색상 및 채도 차이를 이용하여 공간에 대한 변화를 사용자가 쉽게 인지할 수 있도록 하여야 한다. 안내설비의 경우 안내시설의 설치 위치, 안내판의 필수 안내정보, 안내방법 등에 대한 조사가 이루어졌으며, 모든 안내시설에는 승강기, 화장실, 주차장, 비상대피안내 등은 기본적으로 안내가 되어야 하는 내용으로 관련 규정에 반영해야 할 것이다. (결론) 본 연구를 통하여 도출된 개선안은 향후 「장애인등편의법」 등 관련 규정을 개정하는 방향을 설정하는 데에 기초자료로 활용될 수 있을 것이다. 추후 안내시설 표준화와 관련한 후속 연구가 이어져 종합적이고 체계적인 유니버설디자인 안내시스템이 확보되길 기대한다. (Background and Purpose) Korea entered an aging society in 2018, and entry into a super-aged society is just around the corner. In addition, the demand for independence and social participation of the disabled is growing, and although there are responses in all areas of society to respond to this, it is still insufficient. The purpose of this study is to propose an alternative to the universal design guidance system for each space that considers both low-sighted and the disabled, including the elderly, to improve the mobility and accessibility of facility users. (Method) In order to suggest an alternative to the universal design guidance system for each space, this study first reviews the regulations applicable to domestic law through consideration of laws related to domestic and international information facilities. In addition, buildings to which the universal design is applied were selected, information facilities by building convenience facilities were classified, and the installation status of each type of convenience facility such as access roads, stairs, ramps, and corridors was investigated and compared with applicable laws and regulations. Through this, the direction of improvement of the regulations was verified by deriving items that need improvement of the regulations and preparing a survey table of the relevant items and conducting a survey on preference and satisfaction for the elderly, low-sighted, wheelchair users, and people with developmental disabilities. (Results) The guide part of the access road space requires voice guidance, touch guidance, and auditory warnings for guidance and warning. In the case of a single-door door at the door, a braille information sign should be installed on the handle side along with the real name. In the corridor and passage space, it is necessary to install point-shaped blocks at the starting point of the inclined part to make the visually impaired aware, so revision of related regulations is required. In relation to pedestrian obstacles, materials with a large difference in color brightness, color, and saturation should be finished so that obstacles such as indoor pillars can be well recognized, and safety aspects should be considered at the same time in case of a collision. In the case of stairs or ramps and surrounding floor surfaces, the difference in color and saturation should be used so that the user can easily recognize the change in the space. (Conclusions) The improvement plan derived through this study can be used as basic data to set the direction for revising related regulations such as the Convenience Act for the Disabled in the future. Follow-up studies on the standardization of information facilities will continue in the future, and a comprehensive and systematic universal design guidance system will be secured.

      • KCI등재

        Correlations of 3T DCE-MRI Quantitative Parameters with Microvessel Density in a Human-Colorectal-Cancer Xenograft Mouse Model

        안성준,안찬식,금웅섭,송호택,서진석 대한영상의학회 2011 Korean Journal of Radiology Vol.12 No.6

        Objective: To investigate the correlation between quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) parameters and microvascular density (MVD) in a human-colon-cancer xenograft mouse model using 3 Tesla MRI. Materials and Methods: A human-colon-cancer xenograft model was produced by subcutaneously inoculating 1 x 106 DLD-1 human-colon-cancer cells into the right hind limbs of 10 mice. The tumors were allowed to grow for two weeks and then assessed using MRI. DCE-MRI was performed by tail vein injection of 0.3 mmol/kg of gadolinium. A region of interest (ROI) was drawn at the midpoints along the z-axes of the tumors, and a Tofts model analysis was performed. The quantitative parameters (Ktrans, Kep and Ve) from the whole transverse ROI and the hotspot ROI of the tumor were calculated. Immunohistochemical microvessel staining was performed and analyzed according to Weidner’s criteria at the corresponding MRI sections. Additional Hematoxylin and Eosin staining was performed to evaluate tumor necrosis. The Mann-Whitney test and Spearman’s rho correlation analysis were performed to prove the existence of a correlation between the quantitative parameters, necrosis, and MVD. Results: Whole transverse ROI of the tumor showed no significant relationship between the MVD values and quantitative DCE-MRI parameters. In the hotspot ROI, there was a difference in MVD between low and high group of Ktrans and Kep that had marginally statistical significance (ps = 0.06 and 0.07, respectively). Also, Ktrans and Kep were found to have an inverse relationship with MVD (r = -0.61, p = 0.06 in Ktrans; r = -0.60, p = 0.07 in Kep). Conclusion: Quantitative analysis of T1-weighted DCE-MRI using hotspot ROI may provide a better histologic match than whole transverse section ROI. Within the hotspots, Ktrans and Kep tend to have a reverse correlation with MVD in this colon cancer mouse model. Objective: To investigate the correlation between quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) parameters and microvascular density (MVD) in a human-colon-cancer xenograft mouse model using 3 Tesla MRI. Materials and Methods: A human-colon-cancer xenograft model was produced by subcutaneously inoculating 1 x 106 DLD-1 human-colon-cancer cells into the right hind limbs of 10 mice. The tumors were allowed to grow for two weeks and then assessed using MRI. DCE-MRI was performed by tail vein injection of 0.3 mmol/kg of gadolinium. A region of interest (ROI) was drawn at the midpoints along the z-axes of the tumors, and a Tofts model analysis was performed. The quantitative parameters (Ktrans, Kep and Ve) from the whole transverse ROI and the hotspot ROI of the tumor were calculated. Immunohistochemical microvessel staining was performed and analyzed according to Weidner’s criteria at the corresponding MRI sections. Additional Hematoxylin and Eosin staining was performed to evaluate tumor necrosis. The Mann-Whitney test and Spearman’s rho correlation analysis were performed to prove the existence of a correlation between the quantitative parameters, necrosis, and MVD. Results: Whole transverse ROI of the tumor showed no significant relationship between the MVD values and quantitative DCE-MRI parameters. In the hotspot ROI, there was a difference in MVD between low and high group of Ktrans and Kep that had marginally statistical significance (ps = 0.06 and 0.07, respectively). Also, Ktrans and Kep were found to have an inverse relationship with MVD (r = -0.61, p = 0.06 in Ktrans; r = -0.60, p = 0.07 in Kep). Conclusion: Quantitative analysis of T1-weighted DCE-MRI using hotspot ROI may provide a better histologic match than whole transverse section ROI. Within the hotspots, Ktrans and Kep tend to have a reverse correlation with MVD in this colon cancer mouse model.

      • 해조 분해 미생물에 의한 미역 폐기물 중 알긴산 추출

        안성준,우영미,박권필 한국화학공학회 2007 화학공학의이론과응용 Vol.10 No.1

        미역은 채취과정에서 미역의 밑 부분을 잘라서 버리는 부분(미역 폐기물)이 전체의 40∼50%나 된다. 미역 폐기물을 바다에 그대로 버리는 것은, 육지에 끌어내도 적당한 활용방법을 개발하지 못해 또 하나의 육상 폐기물로서 처리해야 하기 때문이다. 미역 폐기물을 유기비료나 사료 등으로 활용할 수 있으나 경제성이 없어 아직 실용화되지 않고 있다. 본 연구에서는, 미역폐기물의 활용방법으로 미역폐기물의 대부분을 차지하는 미역 줄기부분에서 해조류 분해균을 이용해 알긴산을 추출하는 방법을 실험하였다. 알긴산은 콜레스테롤 저하, 간 기능 향상,다이어트 효과가 뛰어나 건강보조식품으로 그 이용이 증가하고 있는데 기존의 알긴산 추출 방법은 알카리를 이용하는 화학적인 방법으로 인체에 해로울 수 있다. 본 실험에서는 해조분해 미생물 DS-02를 배양해 균과 효소액을 분리하고, 이 효소액에 미역줄기를 넣고 각 온도(25∼45℃)에서 교반한 후, 여과하여 얻은 추출액에 알콜을 가해 분리한 알긴산의 수율, 순도, 분자량 등을 측정하였다. 알카리 추출방법에 비해 추출시간은 길었지만 비슷한 수율(약 15%)과 순도를 얻을 수 있었고, 추출과정에서 alginate lyase에 의한, 알긴산의 분해에 의해 분자량이 약 30만에서 3만 정도로 감소해 흡수율이 좋은 알긴산을 얻을 수 있음을 보였다.

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