보리새우육 엑스분의 추출조건과 그 유리아미노산 조성

안미정 부산수산대학교 생명과학연구소 1990 生命科學硏究報告 Vol.1 No.-

간호대학생의 스트레스와 문제음주의 관계에서 대처의 매개효과

안미정 알코올과 건강행동학회 2020 알코올과 건강행동연구 Vol.21 No.2

Objective: In this study, we tried to identify the effects of stress on drinking problems and to check the mediated effects of stress response behavior on nursing college students. Methods: The number of people studied was 163, and the collected data was analyzed using the SPSS/WIN 21.0 statistical program. Hierarchical regression analysis was performed to analyze the mediated effects between stress and problem drinking. Results: Problem drinking showed a positive correlation with stress (r=.258, p≤.001) and also showed a positive correlation with coping (r=.226, p≤.005). In addition, as a result of verifying the mediating effect of avoidance coping, it was found that there was a partial mediation between stress and problem drinking (Z=3.08). Conclusion: In order to improve the mental health of nursing students with high stress levels, it is necessary to first check the level of stress and coping with it. It is necessary to provide a program that reduces avoidance coping and manages stress more efficiently.

초등학교 아동의 인터넷 사용과 불안과의 관계 연구

안미정,이주영 한국간호과학회 2008 한국간호과학회 학술대회 Vol.2008 No.10

아까시나무 뿌리껍질의 항염증활성물질

안미정,강동민,박우성,김혜진,정우진,강권규 한국생약학회 2022 생약학회지 Vol.53 No.1

Robinia pseudoacacia L. (Leguminosae) is widely distributed in Asia, North America and Europe. The root bark has been traditionally used for hemostasis, arthritis and hypertension. Therefore, this study was conducted to identify the biological activity and the bioactive constituents of the root bark. We found that the methanol extract obtained from the root bark of R. pseudoacacia reduced the level of ROS and NO production in LPS-induced inflammation of RAW 264.7 cell line. Among the fractions, methylene chloride fraction showed the highest inhibitory activity against the inflammation. Seven constituents (1-7) were isolated from this fraction, and the chemical structures were determined to be medicarpin (1), (-)-vestitol (2), indole 3-carboxaldehyde (3), 3-acetylindole (4), liquiritigenin (5), 4(1H)-quinolone (6) and 8-methoxyononin (7). Among the isolates, medicarpin (1), (-)-vestitol (2), 3-acetylindole (4) and liquiritigenin (5) inhibited ROS and NO production in a dose-dependent manner. This is the first study to show the anti-inflammatory activity of the root bark of R. pseudoacacia, and it is suggested that the four constituents (1, 2, 4, and 5) could play a role in the biological activity.

Lindera erythrocarpa Makino extract reduces obesity induced by high-fat diet in rats

안미정,Wonjun Yang,Sohi Kang,Min-Chul Kang,Ryeo Kyeong Ko,Gi-Ok Kim,신태균 경희대학교 융합한의과학연구소 2010 Oriental Pharmacy and Experimental Medicine Vol.10 No.4

Lindera erythrocarpa Makino (LE) is widely distributed on Jeju Island, where it has been used for various traditional therapies. Effects of a crude extract of LE were examined in rats with obesity induced by a high-fat diet (HFD). Anti-obesity effects were followed in rats receiving orally administered vehicle, 100mg/kg extract, or 250 mg/kg LE extract, for 56 days. LE extract (250mg/kg) suppressed increases in body weight and epididymal fat, with amelioration of fatty changes in the liver. Additionally, serum levels of alanine aminotransferase, aspartate aminotransferase, and total cholesterol were significantly decreased compared with those of vehicle-treated groups (p <0.05). These results suggest that oral administration of LE extract reduced rat obesity induced by HFD, possibly through the reduction of fat accumulation.

민간약 조릿대의 생약학적 연구

안미정,배지영,박종희 한국생약학회 2009 생약학회지 Vol.40 No.4

Korean folk medicine ‘JoRitDae’ has been used mainly to cure vomiting and cancer. With regard to the botanical origin of ‘JoRitDae’, it has been considered to designate the rhizome of Sasa species (Gramineae), but there was no pharmacognostical confirmation on it. To clarify the botanical origin of ‘JoRitDae’, the anatomical characteristics of the rhizome of Sasa species growing wild in Korea and Japan, Sasa borealis, S, kurilensis, S. quelpaertensis, S. charatacea and S. senanensis were studied. As a result, it was found the morphological criteria for the five Sasa species that could discriminate them by the number of cell layers in cortex, the ratio of thickness of cortex to rhizome radius, the number of cell layers in the va scular bundle sheath, the total number of vascular bundle and thickness of vascular bundle sheath. According to these criteria, it was clarified that the commercial folk medicine ‘JoRitDae’ was the rhizome of Sasa borealis.

만성 폐쇄성 폐질환 환자의 증상경험이 자가 관리에 미치는 영향: 우울과 자기 효능감의 순차적 매개효과

안미정,김현옥 한국간호과학회 2020 한국간호과학회 학술대회 Vol.2020 No.10

Identification and Quantification of Steroidal Saponins in Polygonatum Species by HPLC/ESI/MS

안미정,김진웅 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.5

An HPLC/ESI/MS method has been developed to identify and quantify the spirostanol glycosides in the rhizomes of five Polygonatum species. The relative distribution of two steroidal saponins in each extract was established using the selective ion monitoring (SIM) mode via an electrospray ionization (ESI) source. It was found that there were significant differences in the amount of spirostanol glycosides among the Polygonatum species. The results showed that this method could be used to identify the steroidal saponins in the extracts and differentiate Polygonatum species with high sensitivity and reproducibility in a short time. Fragmentation patterns of the two reference compounds were also discussed with the electrospray ionization multi-stage tandem mass spectroscopy (ESI-MSn).

초등 영재학생과 일반학생의 진로인식, 과학 선호도 및 과학자의 정형화된 이미지 비교

안미정,유미현 韓國英才學會 2012 영재교육연구 Vol.22 No.3

본 연구의 목적은 초등학교 영재학급 학생과 일반학급 학생들의 진로인식과 과학 선호도 및 과학자의 정형화된 이미지를 비교하는 것이다. 본 연구를 위해 초등학교 6학년 영재학생 52명, 일반학생 80명이 연구에 참여하였다. 본 연구의 결과는 다음과 같다. 첫째, 영재학생과 일반학생의 진로인식을 비교한 결과, 영재학생들의 진로인식이 더 높게 나왔으며, 두 집단 간의 유의미한 차이가 나타났다. 이를 통해 전반적으로 일반학생에 비해서 영재학생의 진로인식이 높다는 것을 알 수 있다. 둘째, 영재학생과 일반학급 학생의 과학 선호도는 영재학생이 유의미하게 높은 결과가 나왔다. 하위영역별로 자세히 보면 6개의 모든 하위영역에서 영재학생이 일반학생보다 유의미하게 높았으며, 성별에 따른 비교에서도 영재학생에서만 유의미한 차이가 있었다. 또한 집단과 성별의 차이 간 상호작용 효과는 일반학생에 비하여 영재학생이 과학 학습의 흥미와 학습 지속 실행의지가 높게 나타났다. 셋째, 영재학생과 일반학생의 정형화된 과학자의 이미지 검사를 실시한 결과, 영재학생에 비해 일반학생이 느끼는 과학자의 이미지에서 더 많은 정형화된 모습을 볼 수 있었다. 넷째, 영재학생의 진로인식과 과학 선호도, 진로인식과 과학자의 정형화된 이미지의 상관관계를 살펴본 결과 각각의 변인들 간에 유의미한 상관관계가 나타났다. 다중회귀분석을 통해 진로인식이 과학 선호도에 유의미하게 영향을 준다는 결과를 얻었다. The purpose of this study was to investigate the career awareness, the preference for science and stereotypic image of the scientist between the gifted students and non-gifted students in elementary school. For this study, 52 gifted students and 80 non-gifted students were participated. The results were as follows: First, the career awareness of gifted students was significantly higher than that of non-gifted students. Second, the preference for science of gifted students was significantly higher in all sub-domains than non-gifted students. There was a significant interaction effect between group and gender in the scientific interest and the intention of solving problems. Third, analyzing stereotypic image test for scientist between the gifted students and non-gifted students, it proved that non-gifted students had more stereotypic image comparing with the gifted students. Forth, carrying out the correlation analysis on the career awareness and the preference for science, the career awareness and the stereotypic image of the scientist, it proved that there were significant correlations with each other. It revealed that the career awareness affected the preference for science significantly through multiple regression analysis.

한국의 임금수준과 임금구조에 관한 소고

안미정 中央大學校 社會事業學科 1983 社會福祉硏究 Vol.17 No.1