http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
심인수,최명원,민예지,석광혁,김지연,정지영,옥철호,박인달 대한미생물학회 2016 Journal of Bacteriology and Virology Vol.46 No.1
Tuberculosis (TB) patients are normally treated with a combination of antibiotics. However, with improper or incompletetreatment of antibiotics, the disease may progress to multidrug-resistant TB (MDR-TB). The treatment of MDR-TB is verycostly and inefficient. Therefore, there is a great demand of new therapeutic approaches for MDR-TB such as photodynamictherapy. In this study, we tried to optimize the conditions for photodynamic inactivation of TB using methylene blue as aphotosensitizer. Different combinations of methylene blue concentrations and light doses were tested for their photodynamiceffects to A549 cells or Mycobacterium smegmatis (M. smegmatis). We also tested the effect of photodynamic therapyon ciprofloxacin-resistant M. smegmatis. Methylene blue treatment alone did not affect the survival rates of A549 cellsor bacteria up to 5 μg/ml. When the A549 and M. smegmatis cells treated with methylene blue were irradiated with laserlight (wavelength, 630 nm), photodynamic inactivation of cells was increased in methylene blue concentration- and lightdose-dependent manners. Interestingly, the ciprofloxacin-resistant M. smegmatis exhibited higher level of susceptibilityto methylene blue-mediated photodynamic inactivation. This study suggests that photodynamic therapy at 3.6 J/cm2 inthe presence of 5 μg/ml methylene blue may be an appropriate range for therapy due to the high bactericidal activity againsthigh level of ciprofloxacin-resistant M. smegmatis and the low damaging effect to mammalian cells. This study demonstratesthat photodynamic therapy could be a potential alternative for MDR-TB treatment.
심인수 ( In Su Shim ),김종봉 ( Hong Bong Kim ),조광진 ( Kwang Jin Cho ) 한국환경농학회 2013 한국환경농학회지 Vol.32 No.3
BACKGROUND: As a result of rural exodus, aging of rural population, development of high-yield rice varieties and so on, abandoned paddy fields of South Korea have generally increased. The phytosociological studies are needed to recommend the effective vegetation management methods of abandoned paddy fields. The current study performed an analysis of vegetation characteristics by classifying plant communities for abandoned paddy fields in South Korea. METHODS AND RESULTS: A comparative analysis of syntaxonomy, synecology, and syndynamics was performed by using the Z.-M. method of phytosociology and vegetation survey which was obtained from an enumeration district of total 203 phytosociological releves of 5 regions in Gangwon-do, 5 regions in Gyeonggi-do, 2 regions in Chungcheong-do, 18 regions in Gyeongsang-do, and 10 regions in Jeolla-do. Alopecurus aequalis community, Juncus effusus var. decipiens community and Salix koreensis community were, respectively, identified as successional plant communities of the early stage, the middle stage, and the late stage in the vegetation of abandoned paddy field. Sere of abandoned paddy field can be classified, developmentally, into annual plant stage, perennial plant stage, shrub plant stage, and forest tree stage. Several kinds of dominant species rather than a distinct species were found in the middle stage of abandoned paddy field. CONCLUSION(S): In this study, changing pattern in vegetational communities of abandoned paddy field were understood. These results will provide important information for restoring and conserving the ecology of fallow ground.
가전제품 배송과 설치 서비스의 이원화를 위한 배송 스케줄링 설계 및 분석
심인수(InSoo Sim),김태호(TaeHo Kim),차주일(JuIl Cha),이홍철(HongChul Lee) 한국SCM학회 2011 한국SCM학회지 Vol.11 No.2
In this paper, we proposed delivery model for the dual of appliances delivery and installation services. In order to carry out the proposed delivery model, delivery vehicles and installation services are required the concurrent scheduling. We propose a meta-heuristic algorithm for solving the concurrent scheduling, based on the ant colony system. Scheduling algorithms were developed and existing models and proposed models were compared by executing experiments with scheduling algorithms. Through experiments, the results showed that the proposed delivery model minimizes the number of delivery vehicles and cost more efficiently than existing delivery model.
심인수 ( In Su Shim ),김종봉 ( Jong Bong Kim ),정용규 ( Yong Kyoo Jung ),박인환 ( In Hwan Park ),김명현 ( Myung Hyun Kim ),신현선 ( Hyun Seon Shin ),조광진 ( Kwang Jin Cho ) 한국환경복원기술학회 2015 한국환경복원기술학회지 Vol.18 No.4
Abandoned paddy field provides an excellent opportunity to improve the species diversity and habitat quality. Ecological characteristic on the changing of plant communities at different seral stages is a major basis data for ecological restoration. In this study, we investigated changes of the species composition and community indices on the plant community associated with abandonment of cultivated rice paddies. The ecological stability of the habitat was evaluated by using eco-floristic characters(Di; Disturbance index, AUI; Actual urbanization index). Survey sites were grouped into six stages(stageⅠ (≤3years), stageⅡ(3-5years), stageⅢ(5-7years), stageⅣ(7-10years), stageⅤ(10-15years), stageⅥ(≥ 20years). Vegetation investigation was done from May 2009 to October 2012 and carried out phytosociological approach. The total flora were summarized as 176 taxa including 58 families, 127 genera, 157 species, 3 subspecies, 15 varieties and 1 forms. At each of successional stages, 64 taxa in stage Ⅰ, 34 taxa in stage Ⅱ, 84 taxa in stage Ⅲ, 83 taxa in stage Ⅳ, 92 taxa in stage Ⅴ, 23 taxa in stage Ⅵ were identified. Of the occurrence plants, the species with the highest r-NCD value were Alopecurus aequalis, Juncus effuusus var. decipiens, Persicaria thunbergii, Artemisia princeps, Salix koreensis and Alnus japonica at each stages. Herbaceous annual plants were dominated in the early stage, but its r-NCD value declined in the middle stage and the late stage. On the other hand, herbaceous perennial plants and Persicaria thunbergii, annual hydrophytes, increases in the middle stage. Woody plant and herbaceous plant which appeared in the forest edge increases in the late stage. Community indices correlate with successional stages. Richness and diversity index increase along the successional gradient. But dominance index decrease along the successional gradient. Evenness index was correlated with lower. In the ecological stability analysis of the habitat that evaluated by eco-floristic characters, stage Ⅰ was the most unstable habitat. And the stability of the habitat has improved according to the successional stage.