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중환자실 환자에서 관혈적 기관 절개술과 경피적 확장 기관 절개술의 비교
신현일,장경일,김경민,남인철 대한이비인후과학회 2019 대한이비인후과학회지 두경부외과학 Vol.62 No.5
Background and Objectives Percutaneous dilatational tracheostomy (PDT) has becomean increasingly popular method of establishing an airway for patients in need of chronic ventilatorassistance. The aim of this study is to assess and compare two main strategies for doingtracheostomy: traditional open surgical tracheostomy (ST) and PDT. Materials and Method We retrospectively reviewed medical records of 43 patients who underwenttracheostomy between the years 2016 and 2017. All patients were under intensive careunit (ICU) care and referred to the department of otolaryngology for tracheostomy. All tracheostomieswere performed at the bedside using either percutaneous dilatational technique oropen surgical technique by a single surgeon. In cases of PDT, either blind puncture techniquewithout any guidance or laryngoscopy-guided puncture technique was used. Demographic andprocedural variables and complications were compared between the two groups. Results PDT was performed in 29 patients and ST in 14 patients. Of those who underwentPDT, 15 patients received the blind puncture technique and 14 patients laryngoscopy-guidedpuncture technique. The cricosternal distance was longer and the amount of blood loss and durationof the procedure was lesser in the PDT group. In the PDT group, there was no differencein blood loss nor in the duration of the procedure according to the puncture technique, whereascritical complications occurred more frequently when the blind technique was used. Subjectivedifficulty of the procedure is predictive of complications. Conclusion The study show that PDT is a useful and safe procedure for ICU patients. Also,guidance on using the flexible laryngoscopy during PDT can prevent severe complications.
pH 4.3과 pH 7.0의 과포화용액에서 불소의 농도가 합성 수산화인회석의 결정 성장에 미치는 영향
신현일,박성호,박정원,이찬영 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.1
Objectives: Present study was undertaken to investigate the crystal growth onto synthetic hydroxyapatite (HA) seeds in pH 4.3 and pH 7.0 supersaturated solutions with different fluoride concentrations. Materials and Methods: 8 groups of pH 4.3 and 7.0 calcium phosphate supersaturated solutions were prepared with different fluoride concentrations (0, 1, 2 and 4 ppm). Calcium phosphate precipitates yield crystal growth onto the HA seed surface while solutions flow. For evaluation of crystallizing process, the changes of Ca2+, PO43-, F- concentrations of the inlet and outlet solutions were determined. The recovered solid samples were weighed to assess the amount of minerals precipitated, and finally determined their composition to deduce characteristics of crystals. Results: During the seeded crystal growth, there were significantly more consumption of Ca2+, PO43-, F- in pH 4.3 solutions than pH 7.0 (p < 0.05). As fluoride concentration increased in pH 4.3 solution, Ca2+, PO43-, F- consumption in experimental solutions, weight increment of HA seed, and fluoride ratio in crystallized samples were increased. There were significant differences among the groups (p < 0.05). But in pH 7.0 solution, these phenomena were not significant. In pH 7.0 solutions, analyses of crystallized samples showed higher Ca/P ratio in higher fluoride concentration. There were significant differences among the groups (p < 0.05). But in pH 4.3 solution, there were not significant differences in Ca/P ratio. Conclusions: Crystal growth in pH 4.3 solutions was superior to that in pH 7.0 solutions. In pH 4.3 solutions, crystal growth increased with showed in higher fluoride concentration up to 4 ppm.
신현일,구창덕,조태주 한국버섯학회 2005 한국버섯학회지 Vol.3 No.3
분석 결과, 하나의 decamer primer 로 모든 품종을 구별할 수는 없었지만 10 종류의 decamer를 사용하면 분석에 사용 한 품종을 모두 구별할 수 있는 것으로 나타났다. 분석한 품종 중 290 과 유우지로 품종의 경우 각각 산지가 다른 두 sample을 분석하였는데, 이 경우에서와 같이 품종은 같으나 산지가 다른 경우에도 약간의 차이가 있는 것으로 나타났다. 이와 같은 결과는 품종 식별에 RAPD 분석방법이 매우 유용하게 사용될 수 있음을 보여주는 것이다. 현재의 RAPD 분석결 과에 근거하면 분석에 사용한 10개 sample 은 다음과 같이 다섯 개 group 으로 나눌 수 있는 것으로 나타났다: Group 1: 옥출, Group 2: 기부, Group 3: 115, Group 4: 602, 대구7, 임협6, Group 5: 290(보은), 290(청원), 유우지로(청원), 유우 지로(괴산).
신현일,조태주 대한미생물학회 2013 Journal of Bacteriology and Virology Vol.43 No.1
We have previously observed that a sequence in coat protein (CP) ORF of Turnip yellow mosaic virus (TYMV) isrequired for efficient replication of the virus. The sequence was predicted to take a stem-loop structure, thus termed SL2. While examining various SL2 mutants, we observed that all the modifications resulting in extension of translationbeyond the CP ORF significantly suppressed subgenomic RNA accumulation. The genomic RNA level, in contrast, wasnot affected. Introduction of an in-frame stop codon in the CP ORF of these constructs restored the level of subgenomicRNA. Overall, the results suggest that the read-through makes the subgenomic RNA unstable.
5182 Al합금판의 전기저항 점용접부 피로거동에 관한 연구
신현일,박용석,강성수 대한용접접합학회 1998 대한용접·접합학회지 Vol.16 No.2
On this study, the variations of hardness and microstructure were observed at he spot-welded part of 5182 alminum alloy sheets with thickness of 1.2 mm. The hardness of spot-welded part of aluminum alloy indicated the lowest value at nugget center. Also, the position where fatigue crack exists was investigated by surveying microstructure of the spot-welded sections. Mean load-deformation diagrams were obtained from static tensile test. Fracture was occurred completely within 5 mm after transforming elastic into plastic area. Fatigue test was stopped when the specimens of fatigue test had the final displacement of 0.2mm and measured fatigue bending angle and crack length. This study utilized them, investigated the relations between fatigue bending angle and fatigue crack length and made a estimation of the fatigue fracture life of resistance spot welded part of 5182 aluminum alloy sheet. The relative equation o fatigue crack length and fatigue failure life can be represented by {TEX}$L_{C}${/TEX}=α{TEX}$N_{f}^ {β}${/TEX}.