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^(31)P MR Spectroscopy를 이용한 생체내 골격근 섬유대사의 기능적 특성
성기홍 대한스포츠의학회 1996 대한스포츠의학회지 Vol.14 No.1
Human muscles are composed of two fiber types. All the fibers in a motor unit are of the same type, either fast twitch or slow twitch. Fast twitch fibers are fast contracting and fast to fatigue. They are larger, have fewer capiliaries, and seem best suited for short, intense effort. Slow twitch fibers contract somewhat slower but also are slow to fatigue. They have a rich capillary supply and are well supplied with the internal chemistry required for long-duration endurance activities. In the present work, the time course of changes in [pH] during the maxmal intermittent isokinetic exercise of forearm muscle, characterization of phosphorus high energy metabolism on human skeletal muscle fiber function, were measured by in vivo 31^P MR Spectroscopy. Characterize of phosphorus high energy metabolism on human skeletal muscle fber function by observing different time coures or changes in [pH]. Subjects were ordered to do the forcearm flexion exercise. Well trained oarsmen (n=6) were subjected to a series of 90, 180 seconds of exercises intervaled by 1 minute of resting period until 20 minutes passed the all-out. As the results. 1. The suddenly decreaseing [Low-pH] observed during the exercise by the oarsmen by the oarsmen may indicate that the exercise can be categorized as the fast twitch muscle. 2. The plateau achieved in the time course of [High-pH] during the exercise by the oarsmen may indicate that the exercise can be categorized as the slow twitch muscle. This invasive procedure give only fragmentary and instantaneous information and is in appropriate for frequent follow up in the same individual. In vivo 32^P MR Spectra is a noninvasive thechnique allowing frequent reinvestigation in the same subject without harm. The usefulness of this technique in the study of exercise physiology was evidenced earlied.
성기홍,임태환,신명진,이대근,문치웅,김상태,이덕분 대한스포츠의학회 1993 대한스포츠의학회지 Vol.11 No.1
Nuclear Magnetic Resonance Spectroscopy(NMRS) is biochemical sampling technique that allows the noninvasive quantification of several biomolecules in vivo. Nuclear Magnetic Resonance Spectroscopy to noninvasivly and repeatedly follow muscle metabolism during rest and exercise. We used phorsphorus Magnetic Resonance Spectroscopy to study skeletal muscle metabolism of pro-ball pichter(n=4) The subjects performed work by depressing a pully attached to an isometric contraction of progressive exercise. Relative concentration of Pi and PCr were measured along with intracelluiar pH. Measurements were made at rest during exercise, during recovery from exercise protocol. As a results were ; 1. A variation of pH A recovery after pichting ball. A rest to intracellular from 7.001±0.02 to 6.975±0.04 after Ⅰ Set pichting ball, and become a recovery intracellular pH 6.979±0.04 after 5min(p=0.01), and significant(p<0.05). A rest to intracellular pH from 7.001±0.02 to 6.979±0.06 after Ⅱ Set pichting ball, and become a recovery intracellular pH 6.996±0.02 after 5min(p=0.264), and not significant(p<0.05).