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徐充鎬 고려대학교 의과대학 1978 고려대 의대 잡지 Vol.15 No.1
During starvation man undergoes a series of metabolic adaptations in order to derive energy from adipose tissue and to conserve as efficiently as possible his protein reserves. These are glucose exclusion from the majority of tissues, the Coricycle, and utilization of the ketoacid, thereby sparing glucose and, in turn, body protein. Therefore, this study for effects on the blood sugar level has a important role in the control of diabetic patients and even general healthy patients. The influences of anaesthesia with different induction agents on the blood sugar level during surgery were investigated in eigty cases. Anaesthesia with thiopentone, diazepam, halothane, ketamine and propanidid was accompanied by the rise in blood sugar, although it was differed from the extend the statistical significance. The causes of a rise in blood sugar seem to be the emotional stress of being brought to the operating theatre and the stress of surgery. In the control of the rise in this blood sugar, one must do absolute psychic sadation, avoidance of anoxia and carbon dioxide retention, avoidance of severe surgical stress and adequate depth of anesthesia, thereby can limit the rise in blood sugar, due to occur stimulation of sympathetic nervous system.
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2,3 Diphosphoglycerate値 및 헤모그로빈과의 關係에 對한 硏究
徐充鎬,辛正順 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.3
The role of 2,3 dihposphoglycerate in red blood cell is very important. It decreases the affinity of oxygen to hemoglobin thus improves tissue oxygenation. the purpose of this study is to investigate the ralationship of 2,3 diphosphoglycerate with age and hemnglobin level. Eighty-three patients in both sexes were investigated. Blood sameples were collected between 10 and 30 minutes after induction of anesthesia. The levels of 2,3-DPG were measured by ultraviolet enzymatic method of Sigma Chemical Company. The results were as follows; 1. Mean values for male were 2.79±1.11 μmol/ml (whole blood), 6.81±2.86μmol/ml (packed cells), 20.30±8.57μmol/gm (hemoglobin), and for female were 2.95±1.20μmol/ml (whole blood), 7.86±3.28μmol/ml (packed cells), 23.30±9.95μmol/gm (hemoglobin). 2. Low level of 2,3-DPG were seen in second and fifth decades. 3. The level of 2,3-DPG in smoker was higher than that in nonsmoker. 4. The level of 2,3-DPG showed inverse relationship with hemoglobin level until 13.1-14.0 gm% of hemoglobin, and increasing tendency thereafter.
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Haloperidol 전처치가 진정효과와 수술후 오심 및 구토에 미치는 영향에 관한 연구
길찬일,안동애,서충호,이경자,최세진,신정순 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.3
We used haloperidol as premedicants to be calm and reduce postoperative nausea and vomiting. From April to November, 1976, total 181 cases were evaluated. The results were as followings. 127 cases (70.2%) were indifferent to their surroundings; 22 cases (12.2%) drowsy and completely indifferent to, but, they answered questions adequately. We experienced postoperative nausea and vomiting in subjects (8.3% of all); in each analgesic and anesthetic drug; of 87 patients 5 (5.7%) in pentazocine, of 75 patients 5 (6.7%) in meperidine, no cases were found in halojhane, of 9 paitents 5 (55.6%) in diethyl-ether.
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임상호,김난숙,신정순,서충호 대한마취과학회 1978 Korean Journal of Anesthesiology Vol.11 No.3
To evaluate historical trends, anesthetic experiences of 14, 337 in the total performed at the Korea University Hospital from Jan. 1966 through Dec. 1977 were analyzed statistiCally according to age, sex, department, methods, physical status, duration of anesthesia, induction agents, main agents and anesthetic techiques. The results were as follows: 1) General anesthesia has been used as almost the main method of anesthesia. 2) Patients were about half in the 21~40 group of age. 3) Male patienta were 2. 2 times more than females. 4) The most largest department for surgery was of patients in general surgery. 5) Aceording to the ASA, classification of physical status, patients in class 1 were 43. 5%, and elective surgery to emergency ratio was 1. 3 to 1. 6) Patients in the 1~ 2 hour duration group were 41. 7%. 7) Thiopentone has mainly been used for intravenous induction. 8) Ether had mainly been used for a main anesthetic agent until 1970, but balanced anesthesia has been used with increasing favor since that time. 9) In almost all cases, a semiclosed circle absorption system has been employed and non- rebreathing system has recently been used with increasing favor for pediatric anesthesia.
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이현숙,임상호,신정순,안동애,서충호 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.3
Hyperinsulinism caused by a functioning islet cell tumor of the pancreas is an uncommon but well established metabolic entity which can usually be diagnosed accurately. We treated a patient with functioning insulinoma recently. The outline of the particular management given for the course of the anesthesia of the patient was as follows: 1) Control of blood glucose a) pre- and intraoperative hypoglycemia; Glucose was administered through intravenous drip or orally. b) postoperative transient hyperglycemia; Insulin was administered if necessary and a small amount of glucose uptake, occurred. 2) Anesthetics, and supplemental drugs Drugs with no or little effect in increasing blood glucose were used. 3) Beta-adrenergic blockers These drugs were not used in the hypoglycemic state because of potentiating insulin activity.
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Adrenaline 으로 인한 심장정지와 폐부종 발생에 관한 증례보고
이경자,김난숙,신정순,길찬일,서충호 대한마취과학회 1976 Korean Journal of Anesthesiology Vol.9 No.1
A 13-year-old male developed cardiac arrest and pulmonary edema during an elective surgery for chronic mastoiditis following a local injection of 0. 1 ml of 1: 1000 adrenaline under gene- ral anesthesia. After several days, 14-year-old male developed same episode during tonsillectomy under local anesthesia at ENT out patient department. They showed an immediate and favorable response to treatment with CPPB, rapid digitaliz- ation, fluid therapy, etc. The clinical course and pathophysiology of adrenaline induced pulmonary edema will be discussed.
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