사출·압출 Blow Molding 용 분지폴리카보네이트 수지 개발

서영욱 한국화학공학회 2000 NICE Vol.18 No.5

Non-Destructive Sorting Techniques for Viable Pepper (Capsicum annuum L.) Seeds Using Fourier Transform Near-Infrared and Raman Spectroscopy

서영욱,안치국,이훈수,박은수,모창연,조병관 한국농업기계학회 2016 바이오시스템공학 Vol.41 No.1

Purpose: This study examined the performance of two spectroscopy methods and multivariate classification methods to discriminate viable pepper seeds from their non-viable counterparts. Methods: A classification model for viable seeds was developed using partial least square discrimination analysis (PLS-DA) with Fourier transform near-infrared (FT-NIR) and Raman spectroscopic data in the range of 9080–4150 cm -1 (1400–2400 nm) and 1800–970 cm -1 , respectively. The datasets were divided into 70% to calibration and 30% to validation. To reduce noise from the spectra and compare the classification results, preprocessing methods, such as mean, maximum, and range normalization, multivariate scattering correction, standard normal variate, and 1 st and 2 nd derivatives with the Savitzky-Golay algorithm were used. Results: The classification accuracies for calibration using FT-NIR and Raman spectroscopy were both 99% with first derivative, whereas the validation accuracies were 90.5% with both multivariate scattering correction and standard normal variate, and 96.4% with the raw data (non-preprocessed data). Conclusions: These results indicate that FT-NIR and Raman spectroscopy are valuable tools for a feasible classification and evaluation of viable pepper seeds by providing useful information based on PLS-DA and the threshold value.

Augmentin의 임상효과

서영욱 啓明大學校 醫科大學 1986 계명의대학술지 Vol.5 No.2

The author conducted clinical studies on 33 cases of documented inflammation in pelvie organ who were treated with augmentis, a new orally absorded antibacterial agent comprising the antibiotic, amoxycillin and the β-lactamase inhibitor clavulanic acid, at the Department of Obstetrics and Gynecology, Dong San Medical Center, Keimyung University during the period of May 1985 to October, 1986. The results were as follows: 1. Among 33 cases, (100%), 7 cases of 7 with vaginitis (100%) and one case of 1 with cystitis proved to be very effective. 2. There were 14 cases of culture positive and in general 93% of the cases (3 cases of 3 enterococci (100%), 4 cases of 5β-hemolytic staph. epidermidis, 5 cases of 5 E. coli (100%) and 1 case of 1 hemophillus) obtained successul results. 3. There was no drug side effect in all cases.

Detection of Spinach Juice Residues on Stainless Steel Surfaces Using VNIR Hyperspectral Images

서영욱,모창연,임종국,이아영,김밝금,장재경,김기영 한국농업기계학회 2021 바이오시스템공학 Vol.46 No.2

Purpose Spinach is one of the most commonly consumed fresh-cut vegetables. Hygiene and sanitation in automated processing facilities have been an important issue. This research aimed to develop a line-scan hyperspectral imaging technique for detecting spinach droplets on a stainless steel surface. Methods The hyperspectral imaging system uses UV-A (365 nm) light sources to obtain 3D hypercube data with spatial and spectral data in the visible and near-infrared (VNIR) region ranging from 400 to 1000 nm. Freshly made 100% spinach juice and distilled water were used to prepare juice dilutions at 20%, 10%, 5%, 2%, and 1% juice. For each of the six juice concentrations, fifteen droplets were placed on a stainless steel sheet, and VNIR hyperspectral image data was collected for the 6 × 15 array of droplets on the metal sheet. To detect and classify the diluted droplets on the spectral domain, three classification models (support vector machine, partial least square discriminant analysis, and random forest) and six pre-processing methods were implemented. Results Among them, support vector machine (SVM) showed the best classification accuracy with A = 0.95. Besides, the classification model used to reduce the number of wavelengths and calculation time, the genetic algorithm (GA) applied to the SVM showed the most accurate result as A = 0.90 among three methods. Conclusions The developed classifier demonstrated potential for detecting and classifying spinach juice droplets on the surface of stainless steel sheet metal.

Evaluation of Nonthermal Plasma Treatment by Measurement of Stored Citrus Properties

서영욱,박종률,박회만 한국농업기계학회 2018 바이오시스템공학 Vol.43 No.4

Decay of fruit is one of the greatest issues in fruit storage. Purpose: In this study, citrus sterilization was performed to evaluate a dry sterilization method using an atmospheric-pressure nonthermal plasma treatment based on a dielectric-barrier discharge technique. Methods: Citrus samples were stored under four different environmental conditions as follows: group A had cold storage with plasma treatment with a temperature of 6.2 ± 1.0℃ and relative humidity (RH) of 93.4 ± 8.2%, group B had ambient-temperature storage with 22.9 ± 2.3℃ and 82.1 ± 4.5% RH, group C ambient-temperature storage with plasma treatment with 25.3 ± 2.2℃ and 90.0 ± 2.8% RH, and group D had cold storage with 5.7 ± 1.0℃ and 93.4 ± 6.5% RH. Results: As a result of citrus surface sterilization by plasma treatment, treatment groups A and C together showed an average of 16.1 CFU/mL of mold colonies, while control groups B and D showed an average of 2.2ⅹ102 CFU/mL or approximately 13 times greater than the treatment groups. Regarding the mean concentration of aerobic bacteria colonies, the treatment groups (A and C) and control groups (B and D) showed an average of 7.1 CFU/mL and 1.9ⅹ103 CFU/mL, respectively. This is approximately a 270-fold difference in the concentration of pathogen colonies between treatment and control groups. Conclusions: The results showed the potential of nonthermal plasma treatment for citrus storage in enhancing storage duration and quality preservation.

자궁경암 치료후의 성기능

서영욱,이탁,이태성 대한산부인과학회 1987 대한산부인과학회 학술대회 Vol.60 No.-

帝王切開의 臨床的 統計觀察

徐永旭,金源培,權得基,李重吉,宋文源 최신의학사 1967 最新醫學 Vol.10 No.2

This clinical study disclosed 89 cesarean sections in 2,014 deliveries, during January 1, 1960 and October 1, 1965 at the Dept. of Ob. & Gyn., Taegu Presbyterian Hospital, Taegu, Korea. Results obtained were as follows: 1) 89 cesarean sections in total 2,014 deliveries, an operative incidence of 4.4 per cent, in 5 year and 9 month periods indicates an increase in incidence. 2) The commonest indication of the cesarean section was cephalopelvic disproportion (33.7%), and was followed by placenta previa (20.2%), eclampsia (14.6%), vaginal stricture (7.8%), ruptured uterus (6.8%), repeat section (4.5%), malpresentation (4.5%), abruptio placentae (3.4%), and so forth. 3) The predominant anesthetic method used in this study was local infiltration by I% procaine with 2.5 % pentothal sodium induction and with ether inhalation general anesthesia (73%). There was no anesthetic death. 4) The low cervical type of cesarean sectieon (73%) was the predominant operation used, while the classical cesarean section (20.2%) has not been completely abandoned yet. Cesarean hysterectomy was performed on 8 cases (9.6%). 5) Postoperative maternal morbidity was 19.1 %. 6) Maternal mortality was 2.2%, and death of these 2 cases were due to severe eclampsia per se, and not due to operation. 7) Perinatal mortality was 23.5%. 8) A comparative study of statistics and a review of literature of cesarean section were made.

양수의 구성 성분에 관한 연구

서영욱,윤성도,김택훈 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.11

양수의 합성, 재흡수, 양 및 구성성분의 조절인자에 대한 지식은 최선을 다하여도 아직까지는 제한되어 있으며 여러 가지 실험 및 임상소견을 종합하여도 대충 구도정도만의 정보를 제공하고 있는 실정이다. 아직까지 한국인 양수의 구성성분에 대한 연구가 드물기 때문에 저자들은 계명대학교 의과대학 산부인과학교실에서 정확학 월경력을 가진 산모로서 산전 유전질환의 진단을 위해 임신중기 양수천자를 실시한 임부 37명과 임신말기 선택적 제왕절개 임부 35명을 대상으로 하여 임신중기 양수천자시 여분의 양수와 제왕절개 수술시 양수를 채취하여 본 연구의 재료로 하였으며, 동시에 대상군의 말초혈액을 채취하여 양수와 동일한 검사를 시행하였으며, 대상군을 임신중기와 말기로 나누어 비교 분석하여 아래와 같은 결론을 얻었다. 1. 임신중기 양수천자군의 평균연령은 32.0±3.7세 이었고, 평균임신주순 15.2±0.4주였다. 임신말기 제왕절개군의 평균연령은 27.6±2.2세, 평균임신주수는 39.1±0.3주였다. 2. 임부혈청 glucose는 임신중기와 말기에 81.03±21.71mg/dl, 75.80±18.34mg/dl였고, 양수내에서는 임신중기에 52.00±11.89mg/dl, 말기에 16.86±7.71mg/dl로 중기에 비해 통계적으로 유의한(p$lt;0.05) 감소가 있었고 임부혈청내 수치에 비하여 중기와 말기에 모두 통계적으로 유의하게(p$lt;0.05) 낮았다. 3. Urea nitrogen은 임부혈청내에서 임신중기와 말기에 9.24±2.15mg/dl, 9.23±3.20mg/dl로 차이가 없었고, 양수내에서는 임신중기에 10.92±2.48mg/dl, 말기에 15.60±4.74mg/dl로 통계적으로 유의한(p$lt;0.05) 증가가 있었고, 혈청에 비하여 임신중기 및 말기 모두에서 통계적으로 유의하게(p$lt;0.05) 높았다. 4. 임신중기 및 말기 양수내 creatinine은 0.82±0.29mg/dl, 1.63±0.50mg/dl로 말기에서 중기에 비해 통계적으로 유의한(p$lt;0.05) 증가가 있었고, 혈청내 수치에 비하여 양수내에서 임신말기에 통계적으로 유의하게(p$lt;0.05) 높았다. 5. 임신중기 혈청내 total cholerterol은 173.95±27.84mg/dl이고 임신말기에 229.40±38.14mg/dl로 중기에 비해 말기에 통계적으로 유의한 (p$lt;0.05)증가가 있었고, 양수내에서는 중기에 11.76±8.48mg/dl, 말기에 12.73±11.79mg/dl로 임부혈청에 비해 현저히 낮았다. 6. 임신중기 혈청 총단백은 6.65±1.07g/dl, 말기에 6.15±1.47g/dl로 통계적으로 유의한 차이는 없었고, 양수내 단백은 임신중기에 0.66±0.31g/dl, 말기에 0.52±0.66g/dl로 혈청단백에 비해 아주 낮은 수치였고, 양수내 수치는 임신말기에 감소하나 통계적으로 유의하지는 않았다. 7. 임신중기와 말기 혈청 albumin치는 3.73±0.29g/dl,3.58±0.27g/dl이었고, 양수내에는 0.33±0.24g/dl,0.26±0.31g/dl로 혈청내에서보다 현저히 낮았고, 임신말기에 감소하였으나 통계적으로 유의하지는 않았다. 8. 임부혈청내 bilirubin은 임신중기에 0.57±0.98mg/dl, 말기에 0.46±0.20mg/dl이었고, 양수내에서는 임신중기에 0.17±0.20mg/dl, 말기에 0.04±0.14mg/dl로 말기에 현저한 감소가 있었다. 9. 임신중기 임부혈청내 alkaline phosphatase는 53.24±17.07u/l이었고, 말기에 150.20±54.33u/l 로 현저한 증가가 있었고, 양수내에서도 중기에 32.14±16.80u/l, 말기에 86.54±68.06u/l로 말기에 현저한 증가가 있었다. 10. 혈청내 aspartate aminotransferase는 임신중기와 말기에 22.19±11.15u/l,24.31±5.31u/l로 차이가 없었고, 양수내에서도 12.38±7.45u/l,13.14±6.52u/l호 차이가 없었다. 11. Alanine aminotransferase는 임신중기와 말기혈청내에서 19.03±10.14u/l,16.94±4.40u/l로 통계적으로 유의한 차이가 없었고, 양수내에서도 중기와 말기에 8.78±3.55u/l,9.31±4.21u/l로 통계적으로 유의한 차이가 없었다. 12. 임부혈청내 sodium은 중기와 말기에 137.95±2.36mEq/l, 137.66±3.76mEq/l로 차이가 없었고, 양수내에서는 임신말기에 124.11±6.67mEq/l로 중기의 134.30±1.81mEq/l보다 통계적으로 유의한(p$lt;0.05)감소가 있었다. 13. 혈청내 postassium은 임신중기에 4.02±0.42mEq/l,말기에 4.04±0.27mEq/l로 차이가 없었고, 양수내에서는 임신말기에 4.29±0.51mEq/l로 중기의 3.83±0.21mEq/l보다 통계적으로 유의하게 (p$lt;0.05)높았다. 14. 혈청내 Chloride는 임신중기에 109.76±3.33mEq/l,말기에 111.00±3.09mEq/l로 통계적으로 유의한 차이가 없었고, 양수내에서는 말기에 110.40±5.04mEq/l로 중기의 113.51±4.56mEq/l보다 통계적으로 유의하게(p$lt;0.05)낮았다. 임신중기 양수내 수치는 임부혈청에서보다 통계적으로 유의하게(p$lt;0.05)높았다. 본 연구는 정상임신 15주 전후와 만삭에서 임부혈청 및 양수의 구성성분에 국한된 것이기에 향후 임신전기간에 걸친 연구가 필요하겠으며, 또한 합병증이 동반된 비정상임신에 대한 조사도 요구된다. 아울러 제대천자에 의한 태아혈액내 구성성분도 비교연구가 필요하다고 사료된다. The following paramenters in maternal serum and amniotic fluid were simultaneously estimated at about 15 weeks` gestation in 37 samples of genetic amniocentesis group and term in 35 samples of elective cesarean section group. The maternal serum glucose was 81.03±22.71mg/dl in midtrimester, 75.80±18.34mg/dl in term pregnancy and the amniotic fluid glucose was significantly lower in term(16.86±7.71mg/dl) than midtrimester(52.00±11.89mg/dl)(p$lt;0.05). The maternal serum urea nitrogen was 9.24± 2.15mg/dl in midtrimester, 9.23±3.20mg/dl in term pregnancy and the amniotic fluid urea nitrogen was significantly higher in term(15.60±4.74mg/dl) than midtrimester(10.92± 2.48mg/dl)(p$lt;0.05). The amniotic fluid creatinine was significantly higher in term(1.63± 0.50mg/dl) than midtrimester(0.82±0.29mg/dl)(p$lt;0.05) and significantly higher than maternal serum level in midtrimester and term pregnancy(p$lt;0.05). The maternal serum total cholesterol was significantly higher in term(229.40±38.14mg/dl) than midtrimester(173.95±27.84mg/dl)(p$lt;0.05) and the amniotic fluid level was significantly lower than maternal serum level in midtrimester and term pregnancy(p$lt;0.05). The amniotic fluid total protein was significantly lower than maternal serum level in midtrimester and term pregnancy(p$lt;0.05), and the amniotic fluid albumin level was same as like total protein. The amniotic fluid total bilirubin was significantly lower in term(0.04±0.14mg/dl) than midtrimester(0.17±0.20mg/dl)(p$lt;0.05) and maternal serum level was no difference in midtrimester and term pregnancy. The amniotic fluid alkaline phosphatase was significantly higher in term(86.54±68.06u/l) than midtrimester(32.14± 16.80u/l)(p$lt;0.05) and also maternal serum level was significantly higher in term(150.20± 54.33u/l) than midtrimester(53.24±17.07u/l)(p$lt;0.05). The amniotic fluid amniotransferases were significantly lower than maternal serum in midtrimester and term(p$lt;0.05), but no difference in midtrimester and the term of the amniotic fluid level. The amniotic fluid sodium was significantly lower in term(124.11±6.67mEq/l) than midtrimester(134.30±1.81mEq/l)(p$lt;0.05) and no difference of maternal serum level in midtrimester(137.95±2.36mEq/l) and term pregnancy(137.66±3.76mEq/l). The amniotic fluid potassium was significantly higher in term(4.29±0.51mEq/l) than midtrimester(3.83 ±0.21mEq/l)(p$lt;0.05) and no difference of maternal serum level in midtrimester(4.02± 0.42mEq/l) and term pregnancy(4.04±0.17mEq/l). The amniotic fluid chloride was significantly lower in term(110.40±5.04mEq/l) than midtrimester(113.51± 4.56mEq/l)(p$lt;0.05) and amniotic fluid level was significantly higher than maternal serum level(109.76±3.33mEq/l) in midtrimester pregnancy(p$lt;0.05).

Methotrexate근주로 치유한 자궁경관임신 1예

서영욱,박윤정,이태엽,공두식,배두진,홍순도 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.5

Cervical pregnancy is a rare form of ectopic gestation in which the blastocyst implants in the cervical mucosa below the histologic cervical os. Because of the serious vaginal bleeding, hysterectomy was usually done in the management of cervical pregnancy. Howerver, conservative treatment is desirable for women who want to be pregnancy in the future. Methotrexate has been utilized recently for conservative management of cervical pregnancy. We report a case of cervical pregnancy which was treated succesfully with intramuscular methotrexate injection.

자간전증에서 혈액응고 및 섬유소용해작용의 변동

서영욱,이재호,김택훈,김동석 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.1

To investigate the alterations of clotting and fibrinolytic activities in preeclampsia, the platelet, fibrinogen, D-dimer, plasminogen, antithrombin III activity, a2-plasmin inhibitor and protein C were assayed. The peripheral venous blood was sampled from 20 normal pregnant women as control group and 35 preeclamptic pregnant women as study group in the third trimester. The age and maternal body weight revealed no statistical difference between control and study group. The gestational age was statistically different(p$lt;0.001) between control (40.5+-0.6 weeks) and study group(35.8+-0.8 weeks), but all in the third trimester. The neonatal body weight was also statisticall different(p$lt;0.005) between control(3552.5+-176.4g) and study group(2472.9+-357.9g). There was no statistifical difference between normal pregnancy and preeclampsia in D-dimer, plasminogen and protein C. The platelet count was decreased in preeclampsia compared with normal pregnancy, but statistically not significant. There was a decreasing tendency(p$lt;0.1, p$gt;0.05) of a-plasmin inhibitor in preeclampsia(82.0+- 9.8%, n=25) compared with normal pregnancy(96.0+-7.2%). The fibrinogen showed statisticall siginificant decreases (p$lt;0.001) in preclampsia (359.8+-32.6mg/dl) compared with normal pregnancy(432.7+-28.0mg/dl) and antithrombin III activity showed also statistically significant decrease(p$lt;0.001) in preeclampsla (60.3+-6.1%) compared with normal pregnancy(70.52.2%). The platelet count(p$lt;0.05), antithrombin III activity(p$lt;0.05) and fibrinogen(p$lt;0.05) showed statistically significant discrimination by the stepwise discriminant analysis with platelet count, fibrinogen, D-dimer, plasminogen, antithorombin III activity and protein C as independent variables between normal pregnancy and preeclampsia. Normal pregnancy and preeclampsia could bu classified by the determination of platelets, fibrinogen and antithrombin III activity in 70.9% of the grouped cases. These was statistically significant discrimination between normal pregnancy and preeclampsia in the gestational age(p$lt;0.0001), fibrinogen(p$lt;0.0001) and antithrombin III activity(p$lt;0.0001) by the stepwise discriminant analysis with gestational age as covariable. Normal pregnancy and preeclampsia could be classified by the determination of gestational age, fibrinogen and antithrombin III activity in 83.9% of the goruped cases. The protein C was not changed, but antithrombin III activity was decreased in preeclampsia. It could be concluded that clotting activity was increased in preeclampsia. In the preeclampsia, A plasmin inhibitor showed a decreasing tendency and fibrinogen was significantly decreased, which meant that the fibrinoytic activity was increased with preeclampsia. There was no effect of preeclampsia upon clotting and fibrinolytic activities in the futus.