볏집 도초(稻草)이 DNCB로 유발된 생쥐의 알레르기성 접촉성 피부염에 미치는 영향

박젬마,채중원,Park, Jem Ma,Chae, Joong Won 대한한방소아과학회 2013 대한한방소아과학회지 Vol.27 No.4

Objectives In the theory of Korean medicine, rice straw (RS) has been used effectively as treatments for dyspepsia, diarrhea, enteritis, inflammatory epigastric diseases and various dermatitis. However, the theory has not been studied intensively yet about anti-inflammatory effects for human. This study was to investigate effects of RS for a treatment of allergic contact dermatitis (ACD) induced by 2,4-dinitrochlorobezene (DNCB) in mice. Methods In this experiment, effects of RS were investigated on changes in body weights, dorsum skin thickness, clinical aspects on the dorsum skin, spleen and body weight among these four groups; normal group (NOR), control group (CON), RS spread group (RSS) and RS spread and administer group (RSS+Adm). In addition, the effects on proliferations of splenocytes were also investigated in vitro and in vivo study. Results RSS group and RSS+Adm group showed increasing in body weights, diminished dorsum skin thickness and treated dermatitis on dorsum skin. In RSS+Adm group, spleen weights were lowered significantly compared to CON group. Conclusions In conclusion, these data suggest that RS can decrease symptoms of ACD significantly, and it shows the anti-inflammatory and immunosuppressant effect as well. Therefore, RS can be useful to treat patients with ACD.

소아 뇌전증 (전간(癲癎))에 소아 추나 동시 치료가 미치는 영향에 대한 중의학 연구 고찰

박젬마,Park, Jem Ma 대한한방소아과학회 2021 대한한방소아과학회지 Vol.35 No.4

Objectives The aim of this study is to examine the effects of Pediatric Tuina Massage (PTM) as a treatment of Chlidren's Epilepsy (CE) and to seek guidance for future follow-up studies and the use of Pediatric Tuina Massage (PTM) in clinical setting. Methods The articles were obtained from the China National Knowledge Infrastructure (CNKI) from 2000 to 2021 by key words 'epilepsy', '癲癎', '癲癎病', 'infantile spasm', '婴幼儿痉挛', '小儿发作', '婴幼儿痉挛' and '推拿', '按摩', 'Tuina', 'Chuna', 'massage' in cross combination way. Results Seven articles were selected and analyzed by authors, years published, characteristics, diagnostic criteria, treatment methods and contents, treatment periods, evaluation criteria and research results. Also, stability and side effects were reviewed, and the qualities of the randomized controlled trials (RCT) were evaluated according to Risks of Bias 2 (RoB 2). All studies using Pediatric Tuina Massage (PTM) treatment have achieved effective therapeutic results for treating Children's epilepsy (CE). Conclusion Pediatric Tuina Massage (PTM) is economical, safe without side effects and non-invasive, but still produce a good effect. Also, it is a good treatment option for children who feels anxious of ordinary Korean Medical treatment such as acupuncture, moxa, herbal medicine, which also results in good compliance with the treatment. In addition, it is possible to enhance therapeutic effect by combining it with pharmacological therapies in treating children's epilepsy (CE). Therefore, Pediatric Tuina Massage (PTM) provides an essential clinical basis in guiding further studies for the treatment of CE.

소아 수족다한증의 치험 1례

박젬마,최선욱,채중원,Park, Jem Ma,Choi, Seon Wook,Chae, Jung Won 대한한방소아과학회 2013 대한한방소아과학회지 Vol.27 No.4

Objectives The purpose of this study is to report the clinical effects of Korean medical treatment on the patient with hands and feet Hyperhidrosis. Methods A 9-year-old female patient, who was suffering from Hyperhidrosis on both hands and feet, was treated by Korean herbal medicine (Dangguisayuk-tang gami), acupuncture (Joksamri, Taegyue, Taechoong, Souboo hyul symmetricaly) and moxibustion on the abdomen (Joongwan). Also, VAS scales were used to check the improvement. Results About treating for two months, the patient's hyperhidrosis on both hands and feet were improved by Korean herbal medicine, acupuncture and moxibustion on the abdomen. Conclusions This study showed that Korean medical treatments can be an effective for the hands and feet Hyperhidrosis.

DNCB로 유발된 생쥐의 아토피 피부염에 대한 지실(枳實)의 효능

박젬마,채중원,Park, Jem Ma,Chae, Joong Won 대한한방소아과학회 2015 대한한방소아과학회지 Vol.29 No.1

Objectives The purpose of this study was to investigate the effects of AI on AD induced by DNCB in mice. AI has antiallergic property that is useful in treating allergy-related-diseases, such as asthma, anaphylactic shock, acute bronchitis and skin diseases, skin pruritus from gastrointestinal diseases. However, AI has not been studied intensively yet regarding anti-inflammatory effect on AD. Therefore, this study was conducted on 2,4-dinitrochlorobezene (DNCB)-induced mice to investigate effects of AI in AD. Methods In the experiment, we divided mice into four groups: a normal group (NOR), a control group (CON), an AI spread group (AI spread), and an AI spread and feeding group (AI spread & feeding). Then examined the changes in the body weight, weights of spleen and ear, thickness of dorsum skin and ear skin, clinical aspects on dorsum skin, historical assessments, proliferation of splenocytes in vitro and in vivo, and cytokine (TNF-${\alpha}$, IL-10). Results From the experiment, the ear weight of AI spread & feeding group was significantly dropped and the ear thickness of both AI spread and AI spread & feeding were decreased significantly. Dorsum skin thickness was also decreased significantly in both AI spread and AI spread & feeding group. Also, AI treatment improved the symptoms of AD, such as coloration, erythema and desquamation and had a better effect on AI spread & feeding group. In histopathological observation, thickened epidermis, hyperkeratosis, pigmentation, hypergranulosis, parakeratosis were diminished as well in both AI spread and AI spread & feeding group. In vitro, we could observe when AI was increased as proliferation rate of splenocytes were increased, too. Conclusions In conclusion, these data suggest that AI can decrease symptoms of AD and show AI can be useful herbal therapy for AD.

신경뿌리 병증, 경추부의 증례보고 1례

박젬마,유수향,채중원,Park, Jem Ma,Yu, Soo Hyang,Chae, Jung Won 대한한방소아과학회 2012 대한한방소아과학회지 Vol.26 No.4

Objectives: The purpose of this study is to report the clinical effects of Korean medical treatment on the patient with cervical radiculopathy. Methods: A 16-year-old female patient, who was suffering from the cervical radiculopathy on her Lt. shoulder: ROM limit, swelling and arthralgia, was treated by herbal medicine, physical therapy, acupuncture and pharmacupuncture. Results: As a result, the patient's left upper limb disability was improved by Korean herbal medicine (ssanghwatang hap gamiseokyungtang), hominis placenta (Ja-ha-geou) pharmacupuncture and physical therapy. Conclusions This study showed that Korean medical treatments can be an effective choice for cervical radiculopathy.

소아 자폐스펙트럼 장애의 추나 치료에 대한 중의학 임상 연구 고찰

박젬마,Park, Jem Ma 대한한방소아과학회 2021 대한한방소아과학회지 Vol.35 No.3

Objectives The purpose of this study is to investigate the effect of Tuina treatment for children with Autism Spectrum Disorder (ASD), and to propose guidance to future studies or application in clinical setting. Methods The articles published from year 2000 to May 2021 by China National Knowledge Infrastructure (CNKI) were searched by setting up field as '中醫學', '中藥', '中西醫結合' and by setting up keyword as '小儿自閉症', '儿童自閉症', '自閉症譜系障碍', 'Autism', 'Autism spectrum disorder' that corresponds to participant and '推拿', '導引', '按摩', 'Tuina', 'massage'. Results Nine selected articles were analyzed and summarized by authors and year published, characteristics, diagnostic criteria, treatment methods and contents, treatment duration, evaluation criteria and results of the study. The articles were also reviewed by reported side effects, and evaluated the quality of the study according to Cochrane Handbook's Risk of Bias 2 (RoB 2) assessment of the Randomized Control Trial (RCT) articles. All studies used Tuina treatment to achieve effective results for pediatric autism spectrum disorder. Conclusion Pediatric Tuina treatment (TM) is a non-invasive treatment that does not stimulate patients with unstable ASD but increase patient adherence, and can be safely and simply operated. Therefore, pediatric Tuina treatment is worth utilizing as a clinical basis for further development of ASD treatment.

추나 치료를 적용한 소아 틱장애에 대한 최신 중의학 임상 연구 고찰

박젬마(Jem Ma Park) 대한한의학회 2021 대한한의학회지 Vol.42 No.3

알레르기성 자반증 환아 치험 2례

김빛나래,박젬마,채중원,Kim, Bit Na Rae,Park, Jem Ma,Chae, Jung Won 대한한방소아과학회 2014 대한한방소아과학회지 Vol.28 No.4

Objectives The purpose of this study is to report the clinical effects of Korean herbal medicine and Chimsband treatment in patients with allergic purpura. Methods 4-year-old female patients, who were suffering from allergic purpura were treated by Korean herbal medicine (Samul-tang hap Yukmijihwang-tang gami) and Chimsband treatment. Also, photographs were used to check the improvement. Results After treating for 15 days, the patients' allergic purpura were improved by Korean herbal medicine and Chimsband treatment. Conclusions This study showed that Korean medical treatments could be an effective treatment option in treating allergic purpura.