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      • KCI등재

        Venous Thromboembolism in Children and Young Adults in Korea: Analysis of the Korean Health Insurance Review and Assessment Service Database

        박은실,최형수,이경수,김상원,이재민 대한의학회 2019 Journal of Korean medical science Vol.34 No.49

        Background: Venous thromboembolism (VTE) is very rare in childhood. Nevertheless, its incidence has increased recently. This study aimed to identify risk factors for developing thrombosis in childhood cancers and other childhood diseases through the Korean Health Insurance Review and Assessment Service database. Methods: Data were extracted from the Korean Health Insurance Review and Assessment Service database. Children and young adults from 1 month to 29 years of age were eligible, and 21,747 cases of VTE between January 2008 and December 2016 were identified. Results: The VTE incidence was high in children younger than 1 year of age. After 1 year of age, its incidence decreased rapidly and gradually increased. The VTE incidence for children between 0 and 1 year of age was 10.23-fold higher than that for those between 1 and 5 years of age. Annual VTE incidence increased by year. The age-standardized annual incidence rates were 9.98 per 100,000 population in 2008 and 22.53 per 100,000 population in 2016. The age-standardized annual incidence rate increased 2.25-fold during the 8 years. The lower extremity was the most common site of venous thrombosis. Conclusion: The incidence of VTE in a population younger than 30 years was 13.11 per 100,000 persons in Korea. We found a bimodal age distribution of the VTE incidence with peaks at infancy and again after 16 years. The incidence of portal vein thrombosis was high in infants, and infection and malignancy were the most common comorbidities in patients with VTE.

      • KCI등재

        Limonoid derivatives and its pesticidal activities

        박은실,배인경,전황주,이성은 한국곤충학회 2014 Entomological Research Vol.44 No.4

        Diverse pesticidal activities of anthothecol derived from Khaya anthotheca (Meliaceae) and three limonoids (gedunin, limonin and obacunone) were determined using six phytopathogenic fungi and four insect pests. Anthothecol showed fungicidal activity to Puccinia recondita with control rates of 90, 76 and 53% at concentrations 0.5, 0.25 and 0.1 mg/mL, respectively, while the other limonoids exhibited little inhibitory effect on the fungal survival. The currently used fungicide mancozeb possessed potent fungicidal activity on P. recondite, with 92.3% controlling effect at a concentration of 0.005 mg/mL. Anthothecol exhibited larvicidal activity to Plutella xylostella with 80, 50 and 30% mortality at concentrations of 1.0, 0.5 and 0.25 mg/mL, respectively. Anthothecol showed selective pesticidal activity on P. recondita and P. xylostella. Structural re‐examination of anthothecol was conducted and is reported.

      • KCI등재

        페미니스트 기본소득 논의의 지평확장을 위하여: 고용, 노동 중심 논의에서 성적 주체성 실현 문제를 포함한 논의로

        박은실 한국여성연구소 2014 페미니즘 연구 Vol.14 No.1

        In this article, I examine the importance of income in realization of women’s sexual subjectivity and argue that basic income will play an important role in regard to that matter. For this, I look at the preceding paper on women and income, followed by feminist discussion of basic income. In so doing, I point out that feminist discussion of basic income has been dominantly focusing on its potential effect on gendered division of labor in general, domestic and care work in particular. I argue that there is a hetero-centrisim embedded in it and propose to include the issue of sexuality in general, with women’s sexual subjectivity in particular, in order to extend the framework of analysis of the effects of basic income. For that, I introduce the proposal and the analysis of Carole Pateman and Nancy Fraser in regard to basic income and women. 이 글은 여성의 성적 주체성 실현의 문제에서 소득이 갖는 중요성에 대해 검토하고 소득 보장 문제, 특히, 기본소득 보장이 여성의 성적 주체성 실현을 위해 왜 중요하게 검토되어야 하는지를 살펴본다. 이를 위해 우선, 소득과 여성에 대한 선행논문을 살펴보고, 이어 지금까지의 페미니스트 기본소득 논의를 몇 가지 문제제기와 함께 검토하였다. 필자는 지금까지의 페미니스트 기본소득 논의가 주로 고용과 노동, 특히, 성별노동분업을 중심으로 이뤄져 왔고 여기에는 기혼/이성애 중심성이 작동하고 있다고 지적한다. 필자는 페미니스트 기본소득 논의가 이를 넘어 페미니즘이 주요하게 다뤄왔던 또 하나의 중요한 영역인 섹슈얼리티 문제를 포괄할 수 있도록 논의의 틀을 확장시킬 것을 제안하며 그러한 기본소득 논지의 예로서 주요 페미니스트 기본소득 논자인 캐롤 페이트만과 낸시 프레이저의 논의를 소개한다.

      • KCI등재

        비혼 1인가구 여성의 비상품시장적 삶 생산은 가능할까?

        박은실 부산대학교 여성연구소 2023 여성학연구 Vol.33 No.2

        본 논문은 이윤 축적과 이를 위한 상품 생산을 중심 가치로 두는 자본주의 시장체제 하에서 생활에 필요한 거의 모든 것을 ‘상품’으로 구매해 소비해야 하고 구매력을 가지기 위해서는 인간 자신도 상품을 생산하는 데 쓰일 ‘노동력 상품’으로 판매해야만 하는 구조가 궁극적으로는 삶의 자율성을 파괴하고 질을 악화시킬 뿐이라는 관점에서 출발을 한다. ‘삶 생산’이란 ‘직접적으로 삶을 창조, 재창조, 유지하는 데 쓰이며 다른 목적을 갖지 않는 모든 일’을 가리킨다. 비혼 1인가구 여성들은 대체로 임금노동자이며 생활시간의 대부분을 임금노동에 할애해야 하는 구조에서는 시간 빈곤에 빠지기 쉽고 이로써 삶을 생산하는 일을 외주화, 즉, 상품구매를 통해 해결할 수밖에 없는 순환구조에 빠지기 쉽다. 본 연구는 이에 주목하여 1인가구 생활을 하는 비혼 여성이 이 악순환구조를 넘어 비상품시장적 삶 생산을 할 수 있는 가능성이 있는지, 가능하다면 어떤 조건에서 가능한지 살펴보았다. 이를 위해 1인가구생활을 자발적으로 선택해 대도시, 중도시, 농촌 등에 각각 거주하는 30~60대 비혼 1인가구 여성들을 만나 심층인터뷰하였다. 비혼1인가구생활과 비상품시장적 삶 생산은 현재도 제한적으로나마 공존 가능하지만 이를 위해서는 비상품시장적 삶 생산을 가능하게 하는 연결망에 적극적으로 접속되어 있을 필요가 있었다. 본 논문은 이 망을 ‘비상품시장적 삶 생산 연결망’이라 제시한다. This paper argues that under a capitalist market system that places profit accumulation and 'commodity production' as the central value, almost everything necessary for life must be purchased and consumed as 'commodities', and in order to have purchasing power, most of humans themselves must sell their 'labor power' to be used to produce goods. This paper bases on the perspective that the commodity oriented capitalism as for now ultimately destroys the autonomy of human life and only worsens its quality. ‘Life producing’ refers to ‘all work that is used directly to create, recreate, and maintain life and has no other purpose.’ Women in unmarried single-person households are generally wage workers, and in a structure where they have to devote most of their time to wage labor, it is easy for them to fall into time poverty and fall into a circular structure in which they have no choice but to outsource the work of producing life, that is, by purchasing products. Focusing on this, this study examined whether it was possible for unmarried women living in single-person households to overcome this vicious cycle and create a life outside the commodity market system, and if so, under what conditions. For this purpose, I conducted in-depth interviews with unmarried single-person household women in their 30s to 60s who voluntarily chose to live as a single-person household in large cities, mid-sized cities, and rural areas. I found that unmarried single-person household life and non-commodity market oriented life producing can coexist, albeit to a limited extent, but for this to happen, it was necessary to be actively connected to a social support network that practices the non-commodity market life producing. This network is presented as the ‘non-commodity market oriented life producing network’ in this paper.

      • KCI등재
      • KCI등재

        Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Young Children with Atypical Teratoid/ Rhabdoid Tumor of the Central Nervous System

        박은실,성기웅,백희조,경덕,현진,원성철,임도훈,김흥식,김지혜,구홍회,정유숙,유건희 대한의학회 2012 Journal of Korean medical science Vol.27 No.2

        The feasibility and effectiveness of tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/autoSCT) were evaluated in children younger than 3 yr of age with atypical teratoid/rhabdoid tumors (ATRT). Tandem HDCT/autoSCT was administered following six cycles of induction chemotherapy. Radiotherapy (RT) was administered if the tumor relapsed or progressed, otherwise, it was administered after 3 yr of age. Tumors relapsed or progressed during induction chemotherapy in 5 of 9 patients enrolled; 3 of these 5 received tandem HDCT/autoSCT as a salvage treatment. One patient died from sepsis during induction chemotherapy. The remaining 3 patients proceeded to tandem HDCT/autoSCT; however, 2 of these patients showed tumor relapse/progression after tandem HDCT/autoSCT. All 7 relapses/progressions occurred at primary sites even in patients with leptomeningeal seeding. Toxicities during tandem HDCT/autoSCT were manageable. A total of 5 patients were alive with a median follow-up of 20 (range 16-70)months from diagnosis. Four of 5 patients who received RT after relapse/progression are alive. The probability of overall survival at 3 yr from diagnosis was 53.3% ± 17.3%. Our tandem HDCT/autoSCT is feasible; however, early administration of RT prior to tandem HDCT/autoSCT should be considered to improve the outcome after tandem HDCT/autoSCT.

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